Top list · Portland
AI startups in Portland
18 AI startups in Portland have raised money in rounds we track. These are the 18 that have raised the most, $521M between them.
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PanthalassaPanthalassa is a public-benefit corporation based in Portland, Oregon, founded in 2016.Panthalassa is a public-benefit corporation based in Portland, Oregon, founded in 2016.
Founded 2021Portland, United States$365Mlast round Aug 2026 - 2
ConductorOneConductorOne integrates permission management for the web and modern infrastructure.ConductorOne integrates permission management for the web and modern infrastructure.
Founded 2020Portland, United States$79Mlast round Oct 2025 - 3
Oath SurgicalOath Surgical is a health technology startup founded in 2024 by Dr.Oath Surgical is a health technology startup founded in 2024 by Dr.
Founded 2024Portland, United States$24Mlast round Oct 2025 - 4
Little BirdLittle Bird analyzes social data to deliver insights for smarter enterprise marketing.Little Bird analyzes social data to deliver insights for smarter enterprise marketing.
Founded 2011Portland, United States$15Mlast round Mar 2026 - 5
Caravel BioCaravel Bio is a biotechnology and synthetic biology company based in Portland, Oregon, founded in 2022.Caravel Bio is a biotechnology and synthetic biology company based in Portland, Oregon, founded in 2022.
Founded 2022Portland, United States$9.0Mlast round Oct 2026 - 6
Amboss TechnologiesAmboss Technologies is a payments infrastructure company that focuses on providing businesses with instant payment solutions using stablecoins and Bitcoin.Amboss Technologies is a payments infrastructure company that focuses on providing businesses with instant payment solutions using stablecoins and Bitcoin.
Founded 2021Portland, United States$4.1Mlast round Jun 2026 - 7
Haystack RoboticsAt Haystack Robotics, our global team has united around one core purpose – to develop technologies that provide a cleaner, safer and happier world.At Haystack Robotics, our global team has united around one core purpose – to develop technologies that provide a cleaner, safer and happier world.
Founded 2021Portland, United States$4.0Mlast round Sept 2026 - 8
Reclaim.aiA smart friend for your calendar that automatically makes time for the things you want to get done.A smart friend for your calendar that automatically makes time for the things you want to get done.
Founded 2019Portland, United States$3.8Mlast round Jun 2023 - 9SightglassSightglass is an AI-powered investor relations platform serving both investment managers and capital allocators.
Sightglass is an AI-powered investor relations platform serving both investment managers and capital allocators.
Founded -Portland, United States$3.0Mlast round Dec 2024 - 10
ShelpfulShelpful, Inc.Shelpful, Inc.
Founded 2021Portland, United States$3.0Mlast round Dec 2023 - 11
Sixty AISixty AI is an AI-powered Personal Relationship Management (PRM) platform founded in 2022 and based in Portland, Oregon.Sixty AI is an AI-powered Personal Relationship Management (PRM) platform founded in 2022 and based in Portland, Oregon.
Founded 2020Portland, United States$3.0Mlast round Jun 2023 - 12
AntflySmart agents need needles, not haystacks.Smart agents need needles, not haystacks.
Founded -Portland, United States$2.0Mlast round Sept 2026 - 13
RegulateRegulate is an AI-driven SaaS company for market prediction, product validation, rapid formulation, and real-time regulatory compliance.Regulate is an AI-driven SaaS company for market prediction, product validation, rapid formulation, and real-time regulatory compliance.
Founded 2022Portland, United States$1.9Mlast round May 2026 - 14
CleanHausCleanHaus is an AI-powered operations platform designed for short-term rental hosts and cleaners to automate scheduling and payments.CleanHaus is an AI-powered operations platform designed for short-term rental hosts and cleaners to automate scheduling and payments.
Founded -Portland, United States$1.8Mlast round May 2026 - 15
Health Technology InnovationsHealth Technology Innovations accelerates biomedical imaging with machine learning.Health Technology Innovations accelerates biomedical imaging with machine learning.
Founded 2017Portland, United States$1.0Mlast round Jan 2022 - 16
Customer.ioCustomer.io is a customer engagement platform founded in 2012 and headquartered in Portland, Oregon.Customer.io is a customer engagement platform founded in 2012 and headquartered in Portland, Oregon.
Founded 2012Portland, United States$400Klast round Mar 2022 - 17
Rewire AIRewire AI is a private company founded in 2019 by Dr.Rewire AI is a private company founded in 2019 by Dr.
Founded 2019Portland, United States$276Klast round Aug 2023 - 18
Humans SofttechHumans Softtech is an AI-driven partnership firm focused on creative digital transformation.Humans Softtech is an AI-driven partnership firm focused on creative digital transformation.
Founded 2022Portland, United States$250Klast round Sept 2023
Portland, United StatesCompanies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.
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