Sector portfolio · Accelerator · United States

Y Combinator's Biotech portfolio

Y Combinator has backed 125 Biotech startups in rounds we track, $3.1B between them, shown by the stage each has reached. The best-funded is Ginkgo Bioworks.

125startups backed
5stages
$3.1Braised between them
Pre-seed and seedbiggest stage

Y Combinator's whole portfolioY Combinator's profile

Pre-seed and seed

48

+24 more

Stage not reported

45

+21 more

Series A

15

Series B

11

Series C and later

6

Segment by segment

Pre-seed and seed

48 startups · $328M raised

  1. OnwardOnward is a customer service automation platform that creates a range of automated customer service and sales tools for business usage.Netherlands$122M
  2. SeerSEER is a software company.United States$57M
  3. SAVASava is a multi-management platform that provides an unlimited number of virtual cards as well as automated accounting reconciliation.United Kingdom$21M
  4. Current FoodsCurrent Foods creates plant-based alternatives for people's seafood favorites.United States$18M
  5. iMicrobesiMicrobes, officially known as Industrial Microbes, Inc., is a synthetic biology company based in Alameda, California.United States$10M
  6. Abalone BioAbalone Bio is a preclinical-stage biotechnology company based in Emeryville, California, founded in 2017.United States$7.6M
  7. Pangea Therapeutics Ltd.Pangea Therapeutics Ltd.United States$7.0M
  8. PBPreDxion BioPreDxion Bio is revolutionizing testing and treatment through low-cost, user-friendly at-home diagnostics.-$6.3M

Stage not reported

45 startups · $812M raised

  1. BillionToOneBillionToOne is a precision diagnostics company that focuses on genetic testing for disease detection.United States$280M
  2. Pardes BiosciencesPardes Biosciences is a biotechnology company that develops and commercializes direct-acting antivirals for the treatment of coronavirus.United States$75M
  3. Science ExchangeScience Exchange, the R&D Services Management company, empowers research organizations to accelerate science and drive innovation United States$54M
  4. 54gene54gene is a healthcare startup that offers a genetics testing platform.United States$50M
  5. Alto PharmacyAlto is a digital pharmacy that makes the prescription experience easier.United States$50M
  6. Kernal BiologicsKernalbio creates mRNA therapies that instruct specific cells on how to make their own medicine.United States$48M
  7. Living CarbonLiving Carbon is a public benefit corporation based in Hayward, California, founded in 2019.United States$42M
  8. WWrenUnited Kingdom$21M

Series A

15 startups · $401M raised

  1. Samsara EcoSamsara Eco is an Australian biotechnology and environmental-tech company based in Sydney, specializing in enzymatic recycling technology.Australia$67M
  2. Sensible BiotechnologiesSensible Biotechnologies is a biotechnology company based in Boston, with additional locations in Oxford and Bratislava.Slovakia$51M
  3. SlopeSlope is a B2B financial platform that offers a variety of payment alternatives while being paid immediately.United States$50M
  4. Nabla BioNabla Bio is a biotechnology company founded in 2020 that focuses on developing selective and functional drugs for previously undrUnited States$37M
  5. Ochre BioOchre Bio is a biotechnology company based in Oxford, United Kingdom, founded in 2019.United Kingdom$30M
  6. drchronoThe essential platform for modern medical practices to make care more informed, more interactive, and more personalized.United States$28M
  7. TranscripticTranscriptic is a robotic cloud laboratory for life science.United States$28M
  8. Modern FertilityModern Fertility is a reproductive health company based in San Francisco, founded in 2017.United States$21M

Series B

11 startups · $627M raised

  1. SolugenDiscover the realm of digital intimacy where connections transcend physical boundaries.United States$246M
  2. ContralineContraline is a clinical-stage biotechnology company based in Charlottesville, Virginia, founded in 2015.United States$100M
  3. Lucira HealthLucira Health is a biotechnology company that offers disposable test kits to detect RNA and DNA of infectious diseases.United States$95M
  4. CurebaseCurebase is an AI-powered eClinical software platform that enhances clinical research through decentralized clinical trials (DCTs).United States$40M
  5. LygosLygos provides biotechnology solutions for today’s renewable chemical challenges.United States$35M
  6. Brave CareBrave Care is a pediatric healthcare company focused on providing modern primary and urgent care specifically for children.United States$30M
  7. CCall9United States$24M
  8. SScriptDashUnited States$23M

Series C and later

6 startups · $975M raised

  1. Ginkgo BioworksZymergen is now a part of Ginkgo Bioworks!United States$444M
  2. BenchlingBenchling is a cloud-based platform for biotechnology research and development and the only biology-first platform for scientific United States$162M
  3. Thrive GlobalThrive Global is a behavior change technology company founded in 2016 by Arianna Huffington.United States$123M
  4. uBiomeuBiome is a biotechnology company that offers smart gut tests and clinical microbiome testing services.United States$110M
  5. Carrot FertilityCarrot Fertility is a fertility healthcare company for employers and health plans.United States$90M
  6. CSComprehend SystemsComprehend provides a suite of cloud applications and consulting services that improve the clinical trial process.United States$46M

How this map is made. Every startup here works in Biotech and has raised money in a round we track that names Y Combinator as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026.

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