Sector portfolio · Government fund · United States

US Department of Energy's AI portfolio

US Department of Energy has backed 13 AI startups in rounds we track, $457M between them, shown by the stage each has reached. The best-funded is Mosaic.

13startups backed
2stages
$457Mraised between them
Stage not reportedbiggest stage

US Department of Energy's whole portfolioUS Department of Energy's profile

Segment by segment

Stage not reported

9 startups · $11M raised

  1. eXoZymeseXoZymes develops enzyme-based biomanufacturing solutions that use AI-enhanced, cell-free enzyme systems.United States$5.0M
  2. EquiwattEquiwatt is a digital platform enabling households to get paid for saving energy at peak times.United Kingdom$2.1M
  3. EnviTraceEnviTrace is a creation of cutting-edge machine learning and artificial intelligence (AI/ML) techniques and technologies.United States$1.1M
  4. BastazoBastazo is an AI-driven cybersecurity platform focused on operational technology (OT) security and vulnerability remediation for cUnited States$1.1M
  5. Wildlife Imaging SystemsWildlife Imaging Systems develops a machine vision platform to help the research community conserve wildlife through video capture.United States$1.1M
  6. FR8relayFR8relay is transforming supply-chain and logistics using relay and AIUnited States$300K
  7. Mizar ImagingMizar Imaging is a light sheet illumination system that is modular and designed for high-resolution imaging.United States$257K
  8. Zeus AIZeus AI Ltd is a technology company based in London that specializes in AI agents for sales engagement and customer conversation automation.United States$250K

Pre-seed and seed

4 startups · $446M raised

  1. MosaicAI Workforce Management SoftwareUnited States$341M
  2. EEdenUnited States$104M
  3. MagnefyAIoT Predictive Monitoring for Power InfrastructureUnited States$1.4M
  4. Iris Light TechnologiesIris Light Technologies is a Chicago-based company specializing in nanotechnology and silicon photonics.United States$120K

How this map is made. Every startup here works in AI and has raised money in a round we track that names US Department of Energy as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026.

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