Portfolio map · Private equity · United States
Safeguard Scientifics portfolio map
20 startups Safeguard Scientifics has backed in rounds we track, since 2006, grouped by their main sector. Together they have raised $1.4B. The biggest sector is Biotech, with 7 companies.
Funding by segment
- Biotech$317M7
- Healthtech$232M4
- Advertising & Adtech$636M3
- IT Services$88M3
- Fintech$169M3
Where they are based
- United States20$1.4B
United StatesFounded
1 without a founding year on record.
Total raised
- Under $1M0
- $1M to $10M0
- $10M to $50M11
- $50M to $250M8
- $250M to $1B1
- $1B and over0
Each dot is a startup: the year it was founded across, the total it has raised up (each line is ten times the one below). Pick a segment to pick it out.
19 of 20 startups shown; the rest have no founding year or amount on record.
- 1 to 2
- 3 to 7
- 8 to 24
- 25 to 99
- 100 and more
- United States20
Startups by country, 1 country in all.
Segment by segment
Biotech
7 startups · $317M raised
NuPatheNuPathe is a pharmaceutical company developing solutions for diseases of the CNS, including neurological and psychiatric disorders.United States$93M
Propeller HealthPropeller Health, now operating as Reciprocal Labs Corporation under ResMed, was a digital therapeutics company founded in 2010.United States$70M
Velano VascularVelano Vascular is a medical device innovator committed to enhancing both inpatient blood collection and vascular accessUnited States$58M
SyapseSyapse is a real-world evidence company dedicated to extinguishing the fear and burden of serious disease by advancing real-world United States$45M
Quinnova PharmaceuticalsQuinnova Pharmaceuticals is a biotech company engaged in the development and commercialization of prescription drug products.United States$31M- GBGarnet BiotherapeuticsGarnet BioTherapeutics is a cell therapy company specializing in dermal-based regenerative therapy.United States$10M
CellumenCellumen is an innovator in cellular systems biology solutions that provides an accurate predictions of drug efficacy and safety.United States$10M
Healthtech
4 startups · $232M raised
Sotera WirelessSotera Wireless is a medical device company developing wireless vital signs monitoring devices.United States$92M
Moxe HealthMoxe Health streamlines the bi-directional exchange of clinical data between health plans and provider systems.United States$61M
Trice MedicalTrice Medical specializes in providing solutions for orthopedic diagnostics.United States$60M
Advantedge Healthcare SolutionsAdvantedge Healthcare Solutions designs and develops software for the healthcare industry.United States$20M
Advertising & Adtech
3 startups · $636M raised
MediaMathCreated by MediaMath's industry veterans, the TerminalOneTM Marketing Operating System increases profits and efficiency in digitalUnited States$605M
SpongecellSpongecell helps brands connect with customers wherever they may be.United States$21M
SonobiSonobi is an advertising technology company founded in 2012 and based in Winter Park, Florida.United States$10M
IT Services
3 startups · $88M raised
ApprendaApprenda was a software company based in Troy, NY, founded in 2007.United States$55M
AppFirstAppFirst is redefining the possibilities afforded by next generation IT infrastructure and investments through unprecedented visibility.United States$20M
PneuronPneuron overcomes the time, cost, and complexity associated with traditional enterprise development, deployment and integration approaches.United States$13M
Fintech
3 startups · $169M raised
- CClutchUnited States$122M
TransactisTransactis provides banks and merchants with SaaS-based billing, payment, and loyalty products.United States$37M- TGT-Rex GroupUnited States$10M
How this map is made. Every startup here has raised money in a round we track that names Safeguard Scientifics as an investor, the first in 2006. Each sits under its main sector, read from its rounds, and each sector shows its best-funded first; sectors with fewer than three companies are left off. Rebuilt nightly; updated 15 November 2026.
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