Sector portfolio · VC firm · United States

Polaris Partners' Biotech portfolio

Polaris Partners has backed 75 Biotech startups in rounds we track, $9.1B between them, shown by the stage each has reached. The best-funded is Gossamer Bio.

75startups backed
6stages
$9.1Braised between them
Series C and laterbiggest stage

Polaris Partners's whole portfolioPolaris Partners's profile

Series C and later

23

Series B

20

Stage not reported

15

Series A

12

Growth

3

Pre-seed and seed

2

Segment by segment

Series C and later

23 startups · $3.3B raised

  1. EeGenesisUnited States$329M
  2. Ajax HealthAjax Health accelerates medical innovation through capital and capabilities.United States$320M
  3. AlectorAlector is a biopharmaceutical company that develops therapies for the treatment of neurodegeneration diseases.United States$215M
  4. aTyr PharmaaTyr Pharma (Nasdaq: LIFE) is a biotherapeutics company engaged in the discovery and development of innovative medicines based on United States$181M
  5. Triveni BioTriveni Bio is a clinical-stage biotechnology company based in Watertown, Massachusetts, founded in 2019 through the merger of AmaUnited States$180M
  6. MetacrineMetacrine is a clinical-stage bio pharmaceutical company focused on building an innovative pipeline of best-in-class drugs.United States$173M
  7. OOM1United States$171M
  8. KSQ TherapeuticsKSQ Therapeutics is using CRISPR technology within a powerful drug discovery engine to enable high-confidence drug development.United States$156M

Series B

20 startups · $2.7B raised

  1. Gossamer BioGossamer Bio is a biopharmaceutical company focused on the discovery and development of novel and differentiated therapeutic products.United States$567M
  2. Editas MedicineEditas Medicine is a clinical-stage genome editing company that develops genomic medicines for serious diseases.United States$335M
  3. Cardurion PharmaceuticalsCardurion Pharmaceuticals is a clinical-stage biotechnology company founded in 2017, focused on developing innovative therapeuticsUnited States$260M
  4. CTCapstan TherapeuticsCapstan Therapeutics is advancing cell engineering to develop therapeutics for a broad range of diseases.United States$175M
  5. FIRE1FIRE1, officially known as The Foundry Innovation and Research 1, Ltd., is a connected medical device company based in Dublin, Ireland.Ireland$170M
  6. Cardiac DimensionsCardiac Dimensions is a medical device company based in Kirkland, Washington, founded in 2001.United States$150M
  7. Noema PharmaNoema Pharma is a clinical-stage biotechnology company based in Basel, Switzerland, founded in 2019 by George Garibaldi and Luigi Costa.Switzerland$147M
  8. US HealthVestUS HealthVest is a behavioral healthcare firm that helps the development of psychiatric hospitals.United States$141M

Stage not reported

15 startups · $1.6B raised

  1. FreenomeFreenome is a biotechnology company with a comprehensive multiomics platform for cancer detection using a routine blood draw.United States$553M
  2. Vets First ChoiceVets First Choice provides veterinary practices with an online pharmacy and home delivery services.United States$227M
  3. Leyden LabsLeyden Labs, founded in June 2020 in Leiden, Netherlands, is a biotechnology company focused on developing innovative solutions foNetherlands$221M
  4. Tectonic TherapeuticTectonic Therapeutic is a biotechnology company which focuses on scientific research in biochemistry and molecular pharmacology.United States$185M
  5. BIND TherapeuticsBIND Therapeutics is a biotechnology company incorporated in 2006; Pfizer acquired substantially all of its assets in 2016.United States$138M
  6. InvivydInvivyd develops antibodies to transcend the limitations of the human immune system and fight against viral infections.United States$125M
  7. Arsenal MedicalArsenal Medical develops novel products that improve local therapy for injuries and diseases.United States$60M
  8. 4B480 Biomedical480 Biomedical focuses on the development of a bioresorbable scaffold for treating occlusive disease in the superficial femoral artery.United States$56M

Series A

12 startups · $1.0B raised

  1. Morphic TherapeuticMorphic Therapeutic is a biotechnology company that develops oral integrin therapies to treat serious chronic diseases.United States$328M
  2. Tome BiosciencesTome Biosciences is a biotechnology company based in Watertown, MA, focused on advancing programmable genomic integration (PGI) toUnited States$213M
  3. Kronos BioKronos Bio focuses on the research and development of first-in-class therapies that modulate historically recalcitrant cancer.United States$123M
  4. Paratus SciencesParatus Sciences is a biotechnology startup founded in 2021, based in New York, NY, with a subsidiary in Singapore.United States$100M
  5. IconOVir BioIconOVir Bio is a biotechnology company based in San Diego, California, founded in 2018.United States$77M
  6. Quentis TherapeuticsQuentis Therapeutics is a developer of immuno-therapeutics designed to address ER stress in multiple diseases.United States$49M
  7. Larkspur BiosciencesLarkspur Biosciences is a biotechnology company based in Cambridge and Watertown, founded in 2020.United States$36M
  8. Volastra TherapeuticsVolastra Therapeutics is a biotechnology company developing novel therapies for the treatment of metastatic cancers.United States$30M

Growth

3 startups · $392M raised

  1. GI DynamicsGI Dynamics is a medical device company developing therapies for the treatment of type 2 diabetes and related metabolic diseases.United States$156M
  2. Cerulean PharmaCerulean Pharma develops nanotechnology-based therapeutics for treating oncology, cardiovascular, autoimmune and inflammatory diseases.United States$152M
  3. TARIS BiomedicalTARIS Biomedical is a pharmaceutical company developing therapies for genitourinary system issues.United States$84M

Pre-seed and seed

2 startups · $36M raised

  1. IndomoIndomo is a clinical-stage therapeutics company based in San Francisco, California, focused on developing innovative treatments foUnited States$25M
  2. Cirrus TherapeuticsCirrus Therapeutics is a Biotechnology Research firm diganosing and treating eye diseases affecting ocular immune system.United States$11M

How this map is made. Every startup here works in Biotech and has raised money in a round we track that names Polaris Partners as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026.

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