Sector portfolio · VC firm · United States

Pappas Ventures' Biotech portfolio

Pappas Ventures has backed 13 Biotech startups in rounds we track, $784M between them, shown by the stage each has reached. The best-funded is Ultragenyx Pharmaceutical.

13startups backed
2stages
$784Mraised between them
Series Abiggest stage

Pappas Ventures's profile

Segment by segment

Series A

8 startups · $443M raised

  1. MTMirum TherapeuticsUnited States$120M
  2. RPReneo PharmaceuticalsReneo Pharmaceuticals is an operator of a pharmaceutical company used to develop therapies for patients with orphan metabolic diseases.United States$105M
  3. CCuraSenUnited States$55M
  4. Envisia TherapeuticsEnvisia Therapeutics is a biotechnology company based in Research Triangle Park, North Carolina, established in 2013 by Liquidia TUnited States$46M
  5. RibometrixRibometrix is a platform therapeutics company that discovers small molecule drugs to treat human diseases.United States$45M
  6. OptherionOptherion, Inc., a biotechnology company, develops diagnostic and disease-modifying therapeutics for the management and treatment United States$42M
  7. LTLEAD TherapeuticsLEAD Therapeutics is a drug discovery company developing small molecule IND candidates for the treatment of cancer and infectious diseases.United States$20M
  8. BBoragenUnited States$10M

Series B

5 startups · $342M raised

  1. Milestone PharmaceuticalsMilestone Pharmaceuticals is a drug development company developing small molecule therapeutics for the treatment of cardiovascular diseases.Canada$110M
  2. 4M4D MolecularUnited States$90M
  3. Lumena PharmaceuticalsLumena Pharmaceuticals develops oral therapeutics for rare liver diseases to improve liver function and relieve disease symptoms.United States$71M
  4. Rotation MedicalRotation Medical develops treatments for rotator cuff disease by reversing disease progression and restoring long-term shoulder function.United States$59M
  5. Cequent PharmaceuticalsCequent is a biopharmaceutical company pioneering the development of novel therapeutics to prevent and treat a wide range of human diseases.United States$12M

How this map is made. Every startup here works in Biotech and has raised money in a round we track that names Pappas Ventures as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026.

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