Sector portfolio · VC firm · United States

Essence VC's AI portfolio

Essence VC has backed 22 AI startups in rounds we track, $566M between them, shown by the stage each has reached. The best-funded is Kite.

22startups backed
4stages
$566Mraised between them
Series Abiggest stage

Essence VC's profile

Segment by segment

Series A

10 startups · $411M raised

  1. KiteKite augments coding environment with the use of internet’s programming knowledge and machine learning.United States$236M
  2. ClineCline is an open-source AI coding agent company based in San Francisco, California, founded in 2024 by Saoud Rizwan.United States$27M
  3. RestateRestate is a modern mortgage platform for mortgage loan officers and their clients.Germany$27M
  4. TTeleskopeUnited States$25M
  5. HumanSignalHumanSignal is a software development company based in San Francisco, founded in 2019 and formerly known as Heartex.United States$25M
  6. DistributionalDistributional is an enterprise technology company focused on creating a modern platform for safe and reliable AI.United States$19M
  7. NuonNuon Medical, founded in 2010 by Alain Dijkstra, is a technology partner that enhances conventional cosmetic packaging by integratUnited States$17M
  8. ClarifyClarify is an AI-native, autonomous CRM platform designed for modern revenue teams.United States$15M

Pre-seed and seed

7 startups · $56M raised

  1. SKStandard KernelUnited States$20M
  2. LettaLetta is a San Francisco-based AI startup founded in 2024, specializing in an operating system for building stateful AI agents.United States$10M
  3. OpenInferOpenInfer is an AI inference infrastructure company based in San Mateo, California, founded in 2024.United States$8.0M
  4. Log10Log10 is a food safety testing and quality services company.United States$7.2M
  5. FearnFearn was founded by leading patent professionals from top-tier law firms, and PhDs in artificial intelligence.United States$5.5M
  6. SuperframeSuperframe is an AI software company based in San Francisco, California, founded in 2023.United States$5.0M
  7. MixpeekMixpeek is a multimodal search and indexing platform that processes unstructured data, including videos, images, audio, documents, and text.United States$650K

Stage not reported

3 startups · $29M raised

  1. DevronDevron is a federated data science platform that helps teams build and train AI models on distributed and private data without theUnited States$14M
  2. GraftOur Modern AI platform enables anyone to build production-ready AI apps in a few clicks.United States$10M
  3. ElotlElotl is a San Francisco-based company that specializes in developing a nodeless Kubernetes platform and AI infrastructure engine.United States$5.0M

Series B

2 startups · $70M raised

  1. YYurtsUnited States$40M
  2. ComfyUIComfyUI is a San Francisco-based startup founded in 2023, focusing on an open-source, node-based AI creation engine.United States$30M

How this map is made. Every startup here works in AI and has raised money in a round we track that names Essence VC as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026.

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