Investments abroad · Accelerator · Canada

Creative Destruction Lab's investments in the United States

Creative Destruction Lab, based in Canada, has backed 72 startups in the United States in rounds we track, $1.3B between them, grouped by their main sector.

72startups backed
12sectors
$1.3Braised between them
AIbiggest sector

Creative Destruction Lab's whole portfolioCreative Destruction Lab's profile

AI

17

Biotech

12

Big Data & Analytics

10

Energy

7

Aerospace & Space

7

Advanced Manufacturing

5

Consumer Apps

4

Agtech

2

Healthtech

2

Pharma

2

Manufacturing

2

VR & AR

2

Segment by segment

AI

17 startups · $163M raised

  1. DADarwin AIUnited States$33M
  2. DeepCureDeepCure is a Boston-based company focused on immunology and therapeutics.United States$25M
  3. BBoonUnited States$22M
  4. KyndiKyndi's Natural Language Search solution helps organizations find answers in unstructured, text-based data at unmatched speed and precision.United States$21M
  5. VouchedVouched is a Seattle-based company founded in 2018 that specializes in AI-powered identity verification.United States$17M
  6. Everestlabs.AIEverestlabs.AI develops an AI-based robotics technology to recover valuable recyclables.United States$16M
  7. FiVerityIntelligent Solutions for Cyber Fraud Detection in Financial InstitutionsUnited States$8.5M
  8. GastrographGastrograph uses artificial intelligence to help companies predict and personalize flavor for new food products.United States$7.0M

Biotech

12 startups · $133M raised

  1. Nia TherapeuticsNia Therapeutics develops a precision neurostimulation therapy for the treatment of memory loss.United States$53M
  2. CellFECellFE is a biotechnology and life sciences tools company based in Alameda, California.United States$23M
  3. ECOncreteECOncrete technology provides sustainable solutions for construction of ecologically active infrastructures.United States$19M
  4. Redesign ScienceRedesign Science is a biotechnology company based in New York that specializes in computational drug discovery.United States$17M
  5. Mytide TherapeuticsMytide Therapeutics is a biotechnology company based in Boston, founded in 2018.United States$7.0M
  6. Unravel BiosciencesUnravel Biosciences is a clinical-stage therapeutics company based in Medford, Massachusetts, focused on advancing drug developmenUnited States$4.7M
  7. Obatala SciencesObatala Sciences is a biotechnology firm based in New Orleans, founded in 2017.United States$3.0M
  8. Altay TherapeuticsAltay Therapeutics is a biotechnology company dedicated to harnessing transcription factor (TF) inhibition to develop treatments fUnited States$3.0M

Big Data & Analytics

10 startups · $86M raised

  1. NectarNectar is a fintech platform and working capital marketplace founded in 2021 by Derrick Barker and Brittany Mosely.United States$35M
  2. Revelio LabsRevelio Labs provides an in-depth view into the workforces of companies around the world.United States$15M
  3. PngmePngme, they believe everyone deserves equal access to finance.United States$15M
  4. Strella BiotechnologyStrella Biotechnology offers a biosensing platform that predicts the ripeness of fruit which reduces food waste and improves quality.United States$7.4M
  5. TaplyticsTaplytics is a customer experience automation platform that helps product and development teams enhance the customer journey throuUnited States$5.0M
  6. RillaRilla is an AI coaching platform designed for in-person sales teams, focusing on enhancing offline commerce.United States$3.7M
  7. VyrillVyrill is an AI-powered video commerce and analytics platform founded in 2015 in Silicon Valley.United States$2.5M
  8. Cipher SkinCipher Skin is a Denver-based data company founded in 2017 that specializes in translating the physical world into actionable dataUnited States$1.2M

Energy

7 startups · $718M raised

  1. Antora EnergyAntora Energy is an American energy technology company founded in 2018, focused on developing modular thermal batteries that proviUnited States$565M
  2. Nth CycleNth Cycle is a metal processing technology company working with battery recyclers and miners to recover production-grade critical minerals.United States$137M
  3. Yotta EnergyYotta Energy is a renewable energy technology company based in Austin, Texas, founded in 2016.United States$8.0M
  4. Dynami Battery CorpDynami Battery Corp is a B2B company located in Binghamton, New York, specializing in lithium-ion battery manufacturing technology.United States$6.0M
  5. Element 16 TechnologiesElement 16 Technologies is a cleantech company based in Southern California, founded in April 2016.United States$1.4M
  6. XFlow EnergyXFlow Energy manufactures vertical-axis wind turbines (VAWTs) that reduce the cost of wind energy generation.United States$772K
  7. Capacitech EnergyCapacitech Energy is a technology company based in Orlando, Florida, specializing in advanced energy storage solutions.United States$100K

Aerospace & Space

7 startups · $18M raised

  1. Novo SpaceNovo Space is an aerospace and defense company focused on developing high-performance, radiation-tolerant, modular electronics forUnited States$6.8M
  2. CisLunar IndustriesCisLunar Industries is a Colorado-based space technology startup founded in 2017.United States$2.6M
  3. Kall Morris IncKMI is a space solutions company developing hardware and software technologies to rendezvous, retrieve, and relocate Resident Space Objects.United States$2.5M
  4. Benchmark Space SystemsBenchmark Space Systems is an aerospace company that offers propulsion solutions for small satellite applications.United States$2.4M
  5. Bluefield TechnologiesBluefield Technologies is a digital transformation services and software engineering company specializing in network technologies,United States$2.0M
  6. Precious PayloadPrecious Payload is a US/UAE space-tech startup founded in 2017 by Andrei Maksimov and Andrei Rebrov.United States$1.2M
  7. impossible SensingAt Impossible Sensing, we specialize in science and technology for measuring the scattering and absorption of light.United States$250K

Advanced Manufacturing

5 startups · $18M raised

  1. Red LeaderRed Leader is a technology company based in Mountain View, California, founded in 2018.United States$10M
  2. NANOCHONNanochon is a Washington, DC-based medical device and biotechnology company founded in 2016 by Dr.United States$4.1M
  3. MindTraceMindTrace is a neurosurgical software company based in Pittsburgh, Pennsylvania, founded in 2020 as a spin-off from Carnegie MelloUnited States$3.3M
  4. Build BeyondBuild Beyond is a space junk recycling company building devices that captures, harvest and creates metal structures autonomously in orbit.United States$875K
  5. Alpenglow BiosciencesAlpenglow Biosciences is an end-to-end 3D pathology platform that aims to accelerate drug development and improve clinical diagnostics.United States$250K

Consumer Apps

4 startups · $30M raised

  1. AlunaAluna is an award-winning healthcare technology company focused on improving the management of asthma and chronic respiratory diseases.United States$15M
  2. Reach PlatformReach Platform is a web3 development company focused on simplifying the creation of decentralized applications (DApps).United States$12M
  3. ArcturusArcturus is an AI-powered research and intelligence firm that combines advanced technology with human expertise to provide insightUnited States$2.3M
  4. CubtaleAI Coach for Personalized, Confident Baby CareUnited States$200K

Agtech

2 startups · $6.5M raised

  1. Blue Ocean GearBlue Ocean Gear is a California-based technology startup founded in 2015, focused on developing intelligent tracking solutions forUnited States$4.2M
  2. AdaVivAdaviv is an agriculture technology company based in Boston, Massachusetts, founded in 2018 as a spin-off from the Massachusetts IUnited States$2.3M

Healthtech

2 startups · $5.5M raised

  1. ProbiusDxProbiusDx is an electronic sensing company that provides a diagnostic technology for detecting and monitoring blood concentrations.United States$3.0M
  2. InnoVeinInnoVein develops a medical device designed to offer implants for valve replacement in the femoral vein.United States$2.5M

Pharma

2 startups · $69M raised

  1. Juvena TherapeuticsJuvena Therapeutics is a biopharmaceutical platform which is discovering novel protein-based therapeutics.United States$64M
  2. Navega TherapeuticsNavega Therapeutics is a preclinical stage company developing epigenetic gene therapies for neurological and ophthalmic diseases.United States$5.3M

Manufacturing

2 startups · $4.1M raised

  1. WEAV3DWEAV3D is a manufacturing technology company commercializing revolutionary composite manufacturing processes and processing equipment.United States$2.5M
  2. Leiden Measurement TechnologyLMT is a research and development company specializing in developing high-end scientific instrumentation.United States$1.6M

VR & AR

2 startups · $1.8M raised

  1. PlacenotePlacenote is a B2B software startup that develops a cloud-based Persistent Augmented Reality (AR) SDK.United States$1.0M
  2. TrustPointTrustPoint is developing GPS technology with performance and reliability for automation, infrastructure, and augmented reality.United States$790K

How this map is made. Every startup here has raised money in a round we track that names Creative Destruction Lab as an investor and is based in United States. Each sits under its main sector, read from its rounds, and each shows its best-funded first. Rebuilt nightly; updated 15 November 2026.

More portfolio maps

All portfolios
Investments abroadCreative Destruction Lab's investments in the United Kingdom19 startups · $360MPortfolio mapCreative Destruction Lab portfolio map216 startups · $3.5BCo-investorsWho invests with Creative Destruction Lab124 co-investorsSector portfolioCreative Destruction Lab's AI portfolio66 startups · $1.8BSector portfolioCreative Destruction Lab's Biotech portfolio30 startups · $315MSector portfolioCreative Destruction Lab's Big Data & Analytics portfolio20 startups · $117M

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