Founders · new episode 3 Dec 2025
Lightcone
Hosted by Y Combinator
Y Combinator's partners on what the startups they see are doing, and what works.
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Investors named as guests in the most episode titles on Lightcone.
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- 37What Founders Have To Unlearn To Become Great CEOs3 Dec 2025 · 44 minSpenser Skates▶Show page
About this episode
Spenser Skates has spent more than a decade building Amplitude from a YC startup into a public company, and in that time, he's had to reinvent himself just as much as the product.Joining the Lightcone pod, he talks through the shift from founder to large-company CEO, the skepticism his team initially had toward AI,…
- 36AI Is Eating Logistics14 Nov 2025 · 34 minRyan Petersen▶Show page
About this episode
Logistics is a multi-trillion-dollar industry that quietly powers the entire global economy, and it's shockingly manual.Ryan Petersen, founder & CEO of Flexport, joins the Lightcone to break down how AI is finally touching the physical world: making shipping cheaper, speeding up global trade, and automating work that…
- 35Inside The MIT AI Study Everyone Misunderstood (And What It Means For Startups)30 Oct 2025 · 22 min▶Show page
About this episode
MIT's new State of AI in Business report went viral for claiming that 95% of enterprise AI projects fail. But the real story isn't that AI doesn't work, it's just big companies can't build it.In this episode of the Lightcone, Garry, Harj, Diana, and Jared break down what the study really says, why in-house enterprise…
- 34Unpopular Ideas That Became Billion-Dollar Businesses17 Oct 2025 · 38 min▶Show page
About this episode
Nine out of ten people might tell you you're crazy. The tenth might see what you see.Garry, Harj, Jared, and Diana talk about contrarian bets, the ideas that look impossible until they work. From Uber and Coinbase to DoorDash and Flock Safety, they share how founders find opportunity where others see dead ends.
- 33The 7 Most Powerful Moats For AI Startups3 Oct 2025 · 45 min▶Show page
About this episode
In the early days, the only moat that startups have is speed. Once you make something people want, the question becomes what deeper moats can you build on to defend against the competition?Garry, Harj, Diana, and Jared dive into Hamilton Helmer’s Seven Powers framework to find out how these moats show up in practice…
- 32The FDE Playbook for AI Startups with Bob McGrew12 Sept 2025 · 51 min▶Show page
About this episode
Bob McGrew helped build some of the most influential technologies of the past two decades. Bob was an early engineer at PayPal, an early executive at Palantir, and was recently Chief Research Officer at OpenAI - where he led the development of ChatGPT, GPT-4 ,and the o1 reasoning model.During his time at Palantir, he…
- 31Anthropic Co-founder: Building Claude Code, Lessons From GPT-3 & LLM System Design21 Aug 2025 · 36 min▶Show page
About this episode
Tom Brown co-founded Anthropic after helping build GPT-3 at OpenAI. A self-taught engineer, he went from getting a B-minus in linear algebra to becoming one of the key people behind AI's scaling breakthroughs. And his work is paying off. Today, Anthropic's Claude is the go-to choice for developers, and his team is…
- 30How to Spend Your 20s in the AI Era8 Jul 2025 · 39 min▶Show page
About this episode
AI has upended the once "safe" CS career path. New grads are facing unemployment rates twice those of art history majors, and a CS degree is no longer a surefire ticket to wealth. At the same time, small, focused teams are scaling from zero to eight-figure revenue in months. In a special Lightcone Live at AI Startup…
- 29Alexandr Wang: Building Scale AI, Transforming Work with Agents & Competing With China18 Jun 2025 · 1h 1mAlexandr Wang▶Show page
About this episode
Alexandr Wang started Scale AI to help machine learning teams label data faster.It started as a simple API for human labor, but behind the scenes, he was tackling a much bigger problem: how to turn messy, real-world data into something AI could learn from. Today, that early idea powers a multi-hundred-million-dollar…
- 28State-Of-The-Art Prompting For AI Agents30 May 2025 · 31 min▶Show page
About this episode
At first, prompting seemed to be a temporary workaround for getting the most out of large language models. But over time, it's become critical to the way we interact with AI. On the Lightcone, Garry, Harj, Diana, and Jared break down what they've learned from working with hundreds of founders building with LLMs: why…
- 27Startups Ideas You Can Now Build With AI16 May 2025 · 41 min▶Show page
About this episode
There's never been a better time to start an AI company. Not just because there are new ideas, but because the tech finally makes old ones actually work.On the Lightcone, Garry, Harj, Diana, and Jared talk through the kinds of startups that are suddenly viable thanks to LLMs, from full-stack law firms to personalized…
- 26Windsurf CEO: Betting On AI Agents, Pivoting In 48 Hours, And The Future of Coding2 May 2025 · 53 minY Combinator▶Show page
About this episode
Varun Mohan didn't set out to build one of the fastest-growing AI developer tools. He just knew his company had to change, or die.After initially betting on GPU virtualization, he saw the writing on the wall: if there was a future for his company, it would be at the AI application layer, not infra. Over a single…
- 25How To Navigate Co-Founder Disputes21 Mar 2025 · 42 min▶Show page
About this episode
Technical skills build startups, but oftentimes, people skills can save them. So how do you navigate the disagreements and conflict that inevitably arise with a co-founder? In this episode of the Lightcone, our hosts share what they've learned for managing these critical, yet often overlooked challenges, offering…
- 24Vibe Coding Is The Future5 Mar 2025 · 32 minAndrej KarpathyY Combinator▶Show page
About this episode
Andrej Karpathy recently coined the term “vibe coding” to describe how LLMs are getting so good that devs can simply “give in to the vibes, embrace exponentials, and forget that the code even exists.” In this episode of the Lightcone, the hosts discuss this new method of programming and what it means for builders in…
- 23How AI Is Changing Enterprise19 Feb 2025 · 49 minAaron Levie▶Show page
About this episode
The Lightcone hosts sit down with Aaron Levie, the co-founder & CEO of Box, to hear reports from the front of how large enterprise and Fortune 500 companies are adapting to the AI age.
- 22How To Get AI Startup Ideas7 Feb 2025 · 44 minY Combinator▶Show page
About this episode
Apply to AI Startup School in SF: https://events.ycombinator.com/ai-sus There’s never been a better time to launch an AI startup, but many prospective founders find themselves stuck when it comes to thinking of a good idea. In this episode, the Lightcone hosts look at different ways breakthroughs can be discovered.…
- 21AI Revolution: Why This Is The Best Time To Start A Startup24 Jan 2025 · 39 minRevolutionPaul Buchheit▶Show page
About this episode
In this special episode of Lightcone, we’re joined by YC partner and creator of Gmail, Paul Buchheit, to dig into some of the latest trends in the world of AI and startups. We recorded our conversation at a recent retreat where 300 of the top AI founders in the world gathered to share expertise and make predictions…
- 20The Lightcone 2025 Forecast1 Jan 2025 · 7 min▶Show page
About this episode
Happy New Year! In this mini-episode, the Lightcone hosts ring in 2025 with their predictions for startups, AI, crypto, and more.
- 192024’s Biggest Startup Trends13 Dec 2024 · 38 min▶Show page
About this episode
2024 has been quite a year for AI and startups. As we head into the holidays and the new year, the Lightcone hosts reflect on this year’s biggest startup trends, moments, and breakthroughs.
- 18Vertical AI Agents Could Be 10X Bigger Than SaaS22 Nov 2024 · 42 min▶Show page
About this episode
As AI models continue to rapidly improve and compete with one another, a new business model is coming into view: vertical AI agents. In this episode of the Lightcone, the hosts consider what effect vertical AI agents will have on incumbent SaaS companies, what use cases make the most sense, and how there could be…
- 17Why The Next AI Breakthroughs Will Be In Reasoning, Not Scaling14 Nov 2024 · 35 min▶Show page
About this episode
There's an ongoing debate about whether AI scaling laws will hold or hit a wall in the near future. However, what's clear now is today's models already have the power to increase productivity in ways that would have been unimaginable even a few years ago. In this episode of the Lightcone, we dig into the results of…
- 16The 10 Trillion Parameter AI Model With 300 IQ1 Nov 2024 · 34 min▶Show page
About this episode
Earlier this month, OpenAI raised the largest venture round ever at $6.6 billion. The company’s CFO says AI is now at the point where orders of magnitude matter and the next generation of models will be capital intensive. In this episode of the Lightcone, the hosts consider what a world with ultra-intelligent models…
- 15Now Anyone Can Code: How AI Agents Can Build Your Whole App18 Oct 2024 · 37 minAmjad Masad▶Show page
About this episode
With rapid advancements in LLMs, AI can now follow prompts to generate code and build functional custom software. So, how does the tech landscape change when coding becomes accessible to everyone? In this episode of Lightcone, we sat down with Amjad Masad, CEO of Replit, an AI-powered platform for software development…
- 14Why Vertical LLM Agents Are The New $1 Billion SaaS Opportunities4 Oct 2024 · 37 minJake Heller▶Show page
About this episode
As LLMs continue to improve, it's clear that vertical AI agents are key to the next generation of billion-dollar SaaS opportunities. In this episode of the Lightcone, we sat down with Jake Heller, the co-founder and CEO of Castext, which sold to Thomson Reuters for $650 million in 2023, to discuss what it takes to…
- 13The Hunt for State of the Art (with Suhail Doshi)19 Sept 2024 · 56 min▶Show page
About this episode
Suhail Doshi, a YC alumni who previously founded Mixpanel and Mighty, has created a state-of-the-art (SOTA) AI image diffusion model with Playground. The app allows you to talk to it like a graphic designer and helps you create imagery and text for a wide variety of use cases. In this episode of Lightcone, Suhail sits…
- 12How YC Was Created With Jessica Livingston6 Sept 2024 · 59 minJessica LivingstonY Combinator▶Show page
About this episode
Familiar with the lore of Y Combinator? Then you'll know Jessica Livingston, one of the original co-founders who started YC back in 2005. On a recent visit to our SF headquarters, she shared with the Lightcone hosts the stories and decisions of the early days that would form the foundations of YC as we know it today.
- 11Are We In An AI Hype Cycle?22 Aug 2024 · 38 min▶Show page
About this episode
Is the latest excitement around AI just another round of dot-com or crypto-style hype? The Lightcone hosts discuss where AI might be if the hype cycle is real, and what may remain once the buzz wears off. Apply to YC's first-ever Fall batch at ycombinator.com/apply.
- 10Gmail Creator Paul Buchheit On AGI, Open Source Models, Freedom9 Aug 2024 · 49 minPaul BuchheitGoogle▶Show page
About this episode
It’s the first guest episode of Lightcone! The hosts sit down with Paul Buchheit, one of Google’s earliest employees, the creator of Gmail and current YC Group Partner. (He also came up with Google’s famous tagline “Don’t be evil.”) This discussion covers a wide range of topics including the future of AGI, the early…
- 910 People + AI = Billion Dollar Company?27 Jun 2024 · 38 min▶Show page
About this episode
As AI continues to evolve and advance, a line of thinking has emerged that humans will no longer need to learn how to write code in the future. If so, could this mean that a staff of ten or less could create a unicorn? The hosts of Lightcone analyze this prediction and discuss whether it has merit.
- 8Better AI Models, Better Startups6 Jun 2024 · 41 min▶Show page
About this episode
There's been a lot of news lately about the updates to some of the largest foundational AI models. But what does this mean for startups? How will future product releases from the AI giants effect the companies built on top of them? The hosts of Lightcone discuss how founders can take advantage of these developments…
Who the show talks about
Firms named in its episodes, and people named in descriptions: talked about, rather than on the show.
