Ecosystem map · San Mateo

San Mateo startup ecosystem map

195 startups based in San Mateo that have raised money in rounds we track, grouped by their main sector. Together they have raised $17B; AI is the biggest sector, with 47 companies.

195startups on the map
12sectors
$17Braised between them
AImost funded sector

AI

47

+23 more

IT Services

32

+8 more

Big Data & Analytics

21

Biotech

19

Software

17

Fintech

11

Healthtech

9

Cybersecurity

9

Edtech

9

Cloud

8

Internet

7

Gaming

6

Segment by segment

AI

47 startups · $10B raised

  1. SnowflakeSnowflake is a cloud data platform that provides a data warehouse as a service designed for the cloud.United States$4.6B
  2. Fireworks AIFireworks AI is a generative AI infrastructure platform that specializes in delivering fast inference and full-parameter training United States$1.7B
  3. VerkadaVerkada Inc.United States$1.6B
  4. SkydioSkydio is a leading U.S.United States$350M
  5. GeneralistGeneralist, also known as Generalist AI, is a robotics company based in San Mateo, California, with a mission to develop general-pUnited States$200M
  6. ObserveObserve offers an observability cloud solution to accelerate the transformation of troubleshooting applications and resolving incidents.United States$156M
  7. BigHat BiosciencesBigHat Biosciences is a biotechnology company founded in 2019 and based in San Mateo, California.United States$150M
  8. NotableNotable is an AI-powered health start-up that automates and digitizes every physician-patient interaction.United States$145M

IT Services

32 startups · $410M raised

  1. icixICIX enables real-time coordination across supply chain and trading partner networks to manage sourcing, sustainability, safety anUnited States$75M
  2. B-StockB-Stock is the largest B2B recommerce platform, providing a technology-driven marketplace for businesses to purchase returned, excUnited States$65M
  3. SatmetrixNICE Satmetrix is a global leader in Customer Experience Management (CEM) and Voice of the Customer (VOC) software.United States$51M
  4. CyenceCyence empowers the insurance industry to understand the economic impact of cyber risk.United States$40M
  5. PulsoraPulsora is a public benefit corporation based in San Mateo, California, specializing in enterprise sustainability management.United States$20M
  6. Argyle DataArgyle Data is a machine learning analytics company focused on detecting fraud and revenue threats in mobile carrier networks.United States$19M
  7. CorefinoCorefino Services provides outsourced online accounting solutions for businesses.United States$14M
  8. BBitPassUnited States$13M

Big Data & Analytics

21 startups · $1.2B raised

  1. CloudianCloudian is a file and object storage company that provides hybrid cloud data management software.United States$324M
  2. SnapLogicSnapLogic is a software company that provides a platform for enterprise cloud and big data integration.United States$171M
  3. TileTile, Inc.United States$126M
  4. ExploriumExplorium is a B2B data technology company founded in 2017, headquartered in Tel Aviv, Israel, with additional offices in San MateUnited States$94M
  5. Neo4jNeo4j is a global leader in graph intelligence, recognized for its Neo4j Graph Database, a native graph database management system.United States$80M
  6. RocksetRockset is a real-time indexing database that enables companies to build data applications for the cloud.United States$66M
  7. AlluxioAlluxio is a technology company focused on open-source data orchestration and acceleration for analytics and artificial intelligenUnited States$59M
  8. Jupiter IntelligenceJupiter Intelligence, based in San Mateo, California, is a leader in climate risk analytics, founded in 2017.United States$54M

Biotech

19 startups · $1.1B raised

  1. Bluejay TherapeuticsBluejay Therapeutics is a private biopharmaceutical company focused on the development of cures for infectious diseases.United States$182M
  2. Luma HealthLuma Health is a healthcare technology company founded in 2015 and based in San Mateo, California.United States$152M
  3. AusperBioAusperBio is a clinical-stage biopharmaceutical company dedicated to advancing treatments for hepatitis B virus (HBV) and developiUnited States$113M
  4. CARGO TherapeuticsCARGO Therapeutics develops an adoptive cell therapy to benefit patients from potentially curative treatment options.United States$110M
  5. EpiBiologicsEpiBiologics is a biotechnology company based in San Mateo, California, founded in 2022.United States$107M
  6. Kivu BioscienceAs a company focused on rapidly advancing next generation transformative assets, we leverage our expertise to efficiently progressUnited States$92M
  7. Vivace TherapeuticsVivace Therapeutics is a venture-backed start-up dedicated to discovering and developing cancer therapeutics by targeting a novel pathway.United States$75M
  8. Route 92 MedicalRoute 92 Medical is a medical device company developing a catheter to treat stroke.United States$63M

Software

17 startups · $501M raised

  1. TalendTalend specializes in cloud data integration and data integrity.United States$102M
  2. Lattice EnginesLattice Engines specializes in the fields of marketing, sales, data-driven business applications, and trigger events.United States$65M
  3. SugarSyncWith SugarSync you can backup, access, sync and share all of your documents, photos, music and movies so that you can access them United States$61M
  4. NComputingNComputing provides desktop virtualization software and hardware solutions.United States$58M
  5. Laszlo SystemsLaszlo Systems is an open-source platform providing user experience solutions for apps optimized for mobile and web-enabled devices.United States$50M
  6. newScalenewScale provides self-service portal, service catalogs, and lifecycle management software for enterprise IT and cloud computing.United States$42M
  7. VindiciaVindicia offers #1 payment recovery solution.United States$38M
  8. ApixioConnected Care Platform at the intersection of health plans and providersUnited States$26M

Fintech

11 startups · $2.6B raised

  1. UpstartUpstart connects millions of consumers to 100+ banks and credit unions who leverage Upstart's artificial intelligence models and cUnited States$1.6B
  2. AlpacaAlpaca is a brokerage infrastructure company based in San Mateo, California, that specializes in providing an API-first platform fUnited States$513M
  3. RealiReali was a real estate and fintech company that operated a digital platform to simplify the homeownership journey.United States$240M
  4. Motif InvestingMotif Investing was an online brokerage platform founded in June 2010 by Hardeep Walia and Tariq Hilaly, based in San Mateo, California.United States$127M
  5. Solid Financial Technologies, IncSolid is a California-based fintech platform that provides solutions such as digital banking and payment processing for individualUnited States$63M
  6. OpenEnvoyOpenEnvoy is a financial technology company founded in 2020, based in Las Vegas, Nevada, with additional operations in San Mateo, United States$15M
  7. PrizePoolPrizePool is a financial technology company based in the U.S., founded in 2019.United States$10M
  8. QualpayQualpay is a payment processing company that offers an integrated, cloud-based payments platform.United States$8.0M

Healthtech

9 startups · $365M raised

  1. Cala HealthCala Health is a bioelectronic medicine company based in San Mateo, California, founded in 2013.United States$150M
  2. Salma HealthSalma Health is a comprehensive brain health clinic combining advanced diagnostics, personalized treatment and continuous care undUnited States$80M
  3. Sonitus MedicalSonitus Medical provides clinically effective non-invasive and removable hearing solutions based on the bone conduction method.United States$68M
  4. Health FidelityHealth Fidelity offers risk adjustment and quality solutions for healthcare organizations participating in risk-based payment programs.United States$39M
  5. OpyaOpya is a healthcare technology company based in San Mateo, California, focused on early intervention autism therapy for children United States$15M
  6. Trek HealthTrek Health is an AI-powered healthcare software platform based in San Mateo, California, founded in 2021.United States$11M
  7. StoriiSoftware for Senior CareUnited States$1.7M
  8. Luminate HealthLuminate Health provides a SaaS-based solution that enables patients to access, manage, and understand their lab results.United States$1.0M

Cybersecurity

9 startups · $302M raised

  1. vArmourVArmour offers data defined perimeter security solutions for mobile, virtual, and cloud platforms.United States$144M
  2. Arkose LabsArkose Labs is a global leader in proactive fraud deterrence and account security, based in San Mateo, California.United States$76M
  3. QuSecureQuSecure is a cybersecurity company based in San Mateo, California, specializing in post-quantum cryptography and quantum-safe security.United States$28M
  4. DIDrawbridge Inc.Drawbridge is a cross-device technology firm that enables brands to communicate with individuals.United States$21M
  5. Symmetry SystemsThe Data+AI Security company.United States$18M
  6. DellferDellfer is an IoT and automotive cybersecurity startup that provides tools for devops to add endpoint protection.United States$8.0M
  7. DassanaDassana is a provider of security intelligence solutions focused on enhancing how organizations manage and analyze their cybersecuUnited States$5.0M
  8. LoginIDLoginID is a cybersecurity company that adds biometrics security features to websites, applications, and eCommerce platforms.United States$2.3M

Edtech

9 startups · $312M raised

  1. EdmodoEdmodo is a global education network that connects all learners with the people and resources they need to reach their full potential.United States$88M
  2. Wonder WorkshopWonder Workshop provides a platform that makes programming fun and accessible for children while they play.United States$78M
  3. Swing EducationSwing Education is a technology-driven substitute staffing platform founded in 2015.United States$73M
  4. Education.comEducation.com provides teachers and parents with the learning resources.United States$40M
  5. Tuition.ioTuition.io delivers student loan contributions as a benefit, allowing companies and governments of all sizes to recruit and retain talent.United States$15M
  6. StellicStellic is a degree management and academic planning platform designed for students, advisors, and higher education institutions.United States$14M
  7. RemotebaseRemotebase is a global technology platform and recruitment marketplace that connects companies with pre-vetted remote software engUnited States$2.1M
  8. GoalbookGoalbook empowers teachers to transform instruction so that aLL students succeed.United States$950K

Cloud

8 startups · $52M raised

  1. TernaryTernary is a multi-cloud FinOps platform based in San Mateo, California, founded in 2020.United States$12M
  2. BBitcasaBitcasa provides application program interface and solutions for cloud storage.United States$11M
  3. LightUpBuilding an augmented reality platform for the future of learningUnited States$10M
  4. ComposeCompose is a platform used by developers to deploy, host, and scale databases.United States$6.4M
  5. CirrentCirrent is a company based in San Mateo, California, specializing in software and cloud services for connected and Wi-Fi-enabled products.United States$5.0M
  6. Keen SystemsKeen Systems is a cloud-based platform that allows companies to build and deploy an e-commerce driven web presence.United States$3.4M
  7. CloudastructureCloudastructure provides cloud based infrastructure for building automation - providing VSaaS, ACaaS, and Custom IoT integration sUnited States$3.0M
  8. AngeeAngee is a smart home security company founded in 2015, based in San Mateo, California, with additional offices in London, Prague,United States$470K

Internet

7 startups · $118M raised

  1. NarvarNarvar, Inc.United States$64M
  2. Eightfold LogicEightfold Logic, provides a cloud-based content optimization application.United States$20M
  3. PBworksPBworks is a real-time collaborative editing software that enables businesses to interact with clients in a timely participative atmosphere.United States$17M
  4. FixyaFixya is a community-based trouble-shooting resource that allows individuals to ask and answer questions about tech consumer products.United States$8.0M
  5. greenRushGreenrush facilitates an online marketplace that enables consumers to connect with cannabis dispensary retailers.United States$3.6M
  6. Boom.tvBoom.tv is an eSports entertainment platform based in San Mateo, California, founded in 2015.United States$3.5M
  7. PersistIQPersistIQ is a sales outreach platform that automates prospecting, email outreach, calls, tasks, and social selling.United States$1.8M

Gaming

6 startups · $125M raised

  1. Super Evil Mega CorpSuper Evil Megacorp is an independent game development studio based in San Mateo, California, founded in 2012 by industry veteransUnited States$53M
  2. Manticore GamesManticore Games develops Core, a platform to build, share, and play online games.United States$45M
  3. Roboto GamesRoboto Games is a remote-first video game studio founded in 2013, focused on creating inclusive multiplayer games that enhance socUnited States$15M
  4. MYRMyr is a Delaware-based company specializing in Social VR and multiplayer VR games.United States$10M
  5. SecretBuildersSecret Builders offers online games for children, enabling them to share their ideas, activities and actions.United States$2.3M
  6. Real Life PlusEver wonder what it would look like if a Casual Games and Facebook got married and had a game love child?United States$125K

How this map is made. Every startup here is based in San Mateo and has raised money in rounds we track. Each sits under its main sector, read from its rounds; each sector shows its best-funded first. Rebuilt nightly; updated 15 November 2026.

More market maps

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Market mapMarketing tech market map1,963 startups · 7 segments · $41BMarket mapFintech market map1,633 startups · 8 segments · $139BMarket mapCrypto and Web3 market map1,297 startups · 8 segments · $33BMarket mapFood tech market map1,226 startups · 7 segments · $20BMarket mapEdtech market map1,014 startups · 7 segments · $15BMarket mapGaming market map914 startups · 6 segments · $18B

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