Ecosystem map · Minneapolis

Minneapolis startup ecosystem map

76 startups based in Minneapolis that have raised money in rounds we track, grouped by their main sector. Together they have raised $2.6B; Healthtech is the biggest sector, with 17 companies.

76startups on the map
7sectors
$2.6Braised between them
IT Servicesmost funded sector

Segment by segment

Healthtech

17 startups · $568M raised

  1. EndogenexEndogenex is a clinical-stage medical technology company based in Plymouth, Minnesota, founded in 2017 in partnership with Mayo Clinic.United States$270M
  2. Relievant MedsystemsRelievant Medsystems is a medical device company specializing in diagnosing and treating chronic low back pain.United States$211M
  3. Inbound HealthInbound Health was a healthcare technology and management services company based in Minneapolis, founded in 2022 as a spin-off froUnited States$30M
  4. Reema HealthReema Health is a Minneapolis-based care navigation company that partners with health plans to support members facing social and bUnited States$19M
  5. MD On-LineMDOL provides healthcare information solutions such as healthcare transaction EDI, practice management, EMR, and data analytics.United States$12M
  6. Gem HealthGEM HEALTH, also known as GEM Specialty Health, Inc., is a virtual specialty care company focused on improving the diagnosis and tUnited States$7.0M
  7. Nice HealthcareNice Healthcare provides primary care, physical therapy, and chronic-care management services.United States$6.6M
  8. The Wound CompanyThe Wound Company is a value-based wound care provider in America, established in June 2023.United States$4.3M

IT Services

16 startups · $751M raised

  1. ABILITY NetworkABILITY Network offers CMS-approved, secure Medicare and all-payer online access for claims processing and reimbursement.United States$583M
  2. Perfecto MobilePerfecto is a software system helping users strengthen their digital interaction with quality-first approach to create web and native apps.United States$84M
  3. Field NationField Nation is a leading labor marketplace for on-site IT field services, founded in 2008 and based in Minneapolis, Minnesota.United States$30M
  4. AppFirstAppFirst is redefining the possibilities afforded by next generation IT infrastructure and investments through unprecedented visibility.United States$20M
  5. VidkuVidku is a mobile video sharing application founded in 2012 and based in Minneapolis, Minnesota.United States$17M
  6. FieloFielo is a global enterprise software company based in Minneapolis, Minnesota, with significant operations in Rio de Janeiro, Brazil.United States$7.0M
  7. ColdCold Climate PBC is a Minneapolis-based public benefit corporation focused on simplifying Extended Producer Responsibility (EPR) cUnited States$2.6M
  8. ProsperStackProsperStack is a Minneapolis-based technology company founded in 2020, focusing on customer retention and acquisition software foUnited States$2.0M

Software

12 startups · $108M raised

  1. LeadPagesLeadpages is a tool that lets you create launch pages, sales pages, pop ups, and other conversion pages.United States$38M
  2. ConservisConservis is a software solutions provider developing and implementing compliance, tracking, traceability and performance management tools.United States$24M
  3. TamaracKModern, end-to-end software for wood processing businessesUnited States$17M
  4. MGmPay GatewaymPay Gateway is a PCI certified acquiring card processor that delivers bankcard solutions with integrated web-based management software.United States$9.2M
  5. DEDigital EvolutionDigital Evolution is a provider of Web services management products.United States$8.0M
  6. CalabrioCalabrio is a software company that provides an easy to use workforce optimization suite for contact centers.United States$8.0M
  7. Refr SportsRefr Sports is a Minneapolis-based software company founded in January 2022.United States$2.3M
  8. PreciouStatusPreciouStatus is a technology company based in Minneapolis, Minnesota, that focuses on enhancing communication between families anUnited States$1.2M

Biotech

11 startups · $423M raised

  1. CVRxCVRx is a medical device company developing implantable technology for the treatment of high blood pressure.United States$369M
  2. Sansoro HealthSansoro Health is a healthcare information technology companyUnited States$13M
  3. Silk TechnologiesSILKTECH focuses on innovating and developing silk-derived protein (SDP) products for ophthalmic applicationsUnited States$11M
  4. Aptitude Medical SystemsAptitude Medical Systems focuses on the potential of aptamers to solve the fundamental problems of antibodies.United States$10M
  5. RetraceHealthRetraceHealth was a healthcare startup based in Minneapolis that focused on providing accessible primary care through telemedicineUnited States$8.5M
  6. Evia BioEvia Bio is a life science innovation company based in Minneapolis, focused on the cell and gene therapy market.United States$5.5M
  7. FOXO TechnologiesFOXO Technologies transforms the global longevity insurance industry with a next-generation underwriting protocol.United States$1.5M
  8. Clinician NexusClinician Nexus is a healthcare technology company based in Minneapolis, founded in 2016.United States$1.5M

AI

9 startups · $35M raised

  1. OTTO SPORT AIOTTO SPORT AI is a youth sports technology company based in Minneapolis.United States$17M
  2. TamberTamber treats depression, anxiety, panic attacks, and bipolar disorders.United States$5.0M
  3. SpawningSpawning is an AI company dedicated to ensuring consent, provenance, and compliance in AI training data.United States$3.0M
  4. Blank MetalBlank Metal is an AI-native engineering company based in Minneapolis, specializing in AI-enabled software and engineering solutions.United States$3.0M
  5. LucyLucy®, an AI-Powered Knowledge Management AssistantUnited States$2.5M
  6. GwoopGwoop Inc.United States$1.9M
  7. NextGemAI-driven matchmaking platform for trading card collectors.United States$1.8M
  8. EXtranceEXtrance is a commercial real estate investment platform with notable AI, machine learning, and blockchain integrationUnited States$1.0M

Fintech

6 startups · $512M raised

  1. SezzleSezzle provides a buy now, pay later solution platform.United States$331M
  2. NeuehealthNeuehealth is a healthcare company that builds partnerships with health systems and care providers to create healthcare networks.United States$150M
  3. ClickSwitchClickSWITCH is an automated account switching solution for financial institutions and FinTechs.United States$17M
  4. OnsettoOnsetto is a financial technology company based in Minneapolis, founded in 2025.United States$9.0M
  5. ApruveApruve manages and finances B2B credit programs.United States$6.1M
  6. ActifiActiFi is a software and solutions company focused on advisor success in the financial services industry.United States$138K

Internet

5 startups · $163M raised

  1. Code42Code42 is a Minnesota-based cybersecurity firm that provides solutions such as risk detection and threat management for sectors inUnited States$138M
  2. FoodsbyFoodsby is a food-technology company and lunch delivery marketplace founded in May 2012 by Ben Cattoor and Parag Shah, based in MiUnited States$20M
  3. KidizenKidizen is the peer-to-peer marketplace for parents to shop and sell kids' clothing, shoes, accessories, and more.United States$4.8M
  4. OtterologyShopventory is a Colorado-based SaaS platform that offers solutions such as customized POS integration, inventory management, and United States$850K
  5. SESlice EngineSlice Engine is a user generated content platform that focuses on hyper-local, brand-sponsored social networks.United States$200K

How this map is made. Every startup here is based in Minneapolis and has raised money in rounds we track. Each sits under its main sector, read from its rounds; each sector shows its best-funded first. Rebuilt nightly; updated 15 November 2026.

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