Ecosystem map · Irvine

Irvine startup ecosystem map

103 startups based in Irvine that have raised money in rounds we track, grouped by their main sector. Together they have raised $4.0B; Biotech is the biggest sector, with 23 companies.

103startups on the map
9sectors
$4.0Braised between them
Biotechmost funded sector

Biotech

23

IT Services

18

Healthtech

16

Software

11

AI

8

Fintech

8

Medical Devices

7

Proptech

6

Big Data & Analytics

6

Segment by segment

Biotech

23 startups · $1.2B raised

  1. Beta BionicsBeta Bionics is a biotechnology company that develops an integrated bionic pancreas system called the iLet.United States$296M
  2. CG OncologyCG Oncology is a clinical-stage biopharmaceutical company focused on the development of oncolytic immunotherapies to combat cancer.United States$238M
  3. EvolusEvolus medical aesthetics focused on providing physicians and their patients with expanded choices in aesthetic procedures and treatments.United States$150M
  4. Cloudbreak TherapeuticsCloudbreak Therapeutics is a clinical stage biotechnology companyUnited States$130M
  5. Ambros TherapeuticsAmbros Therapeutics is a clinical-stage biotechnology company.United States$125M
  6. SilveradoSilverado Senior Living, based in Irvine, California, specializes in memory care and assisted living for individuals with memory iUnited States$51M
  7. Vascular DynamicsVascular Dynamics is a medical device company founded in 2008 and headquartered in Irvine, California.United States$46M
  8. AgendiaAgendia is a molecular diagnostics company focused on precision oncology, specifically for early-stage breast cancer.United States$35M

IT Services

18 startups · $116M raised

  1. Local.comLocal.com owns and operates a leading local search site and network in the United States.United States$43M
  2. Zadara StorageZadara Storage offers enterprise-class storage as a service for private and public clouds.United States$23M
  3. CirroCirro provides easy, high-performance solutions for today's most challenging database management issues spanning secure access, daUnited States$9.0M
  4. SpireonSpireon connects companies to their mobile assets and workforce.United States$7.7M
  5. ThumbThumb Technologies is an AI-powered company that specializes in conversational analytics.United States$7.2M
  6. Phoenix Energy TechnologiesPhoenix Energy Technologies is a property-technology company based in Irvine, California, founded in 2004.United States$5.0M
  7. Performa LabsPerforma Labs provides a software platform that allows faster, safer training for professionals with mission-critical careers.United States$4.6M
  8. Accenx TechnologiesAccenx Technologies provides health information exchange and interoperability solutions.United States$4.5M

Healthtech

16 startups · $323M raised

  1. Axonics Modulation TechnologiesAxonics Modulation Technologies is a pre-revenue company developing novel implantable neuromodulation.United States$144M
  2. lensgenLensGen creates adaptive intraocular lenses for the treatment of presbyopia.United States$34M
  3. TelesairTelesair is a medical device company developing respiratory care solutions.United States$25M
  4. MCMiCardia CorporationMiCardia is a privately held medical device company developing technology platforms to optimize mitral valve repair.United States$23M
  5. TheraheartTheraheart is a medical device company that offers innovative, minimally invasive solutions for heart failure.United States$21M
  6. Moving AnalyticsMoving Analytics is a telehealth service provider that specializes in cardiovascular prevention programs.United States$20M
  7. LifeMasters Supported SelfCareLifeMasters Supported SelfCare was a healthcare company based in Irvine, California, founded in 1994.United States$15M
  8. MeaCorMeacor is a healthtech startup focused on cardiovascular innovation and the development of minimally invasive medical devices.United States$15M

Software

11 startups · $201M raised

  1. BlueCavaBlueCava is a fast growing provider of cross screen reach, targeting and measurement products for brands, advertisers, data companUnited States$65M
  2. UplogixUplogix provides network monitoring and management solutions that improve control, connectivity and security.United States$45M
  3. NumecentNumecent develops a 'cloudpaging' technology that transmits pre-virtualized native software instructions in a transient manner.United States$31M
  4. SecureAuthSecureAuth is an identity and access management company that delivers a truly passwordless continuous experience to everyone, everywhere.United States$28M
  5. KofaxDigitally Transform Your Information-Intensive Workflows.United States$11M
  6. Arkeia SoftwareArkeia Software delivers enterprise-class solutions for data backup and disaster recovery.United States$7.0M
  7. Vangard Voice SystemsVangard Voice Systems is the provider of AccuSpeechMobile voice technology and mobile voice platform for enterprise-wide voice deployment.United States$5.0M
  8. Buy It Installed, Inc.Buy It Installed, Inc.United States$4.5M

AI

8 startups · $1.2B raised

  1. FieldAIFieldAI is the general-purpose brain making robots autonomous in complex, risky, real-world environments.United States$1.1B
  2. SyntiantSyntiant is a deep learning tech company providing AI voice and sensor solutions.United States$40M
  3. GATC HealthGATC Health Corp.United States$26M
  4. EphesoftIntelligent Document Processing PlatformUnited States$15M
  5. BitvoreBitvore is an AI-powered intelligence company based in Irvine, California.United States$14M
  6. Huckleberry LabsHuckleberry Labs is a data-driven company focused on pediatric sleep research and wellness solutions for families.United States$13M
  7. TTThumb TechnologiesThumb Technologies is a provider of virtual meeting assistant solutions for the future of work.United States$1.0M
  8. Target EagleTarget Eagle is a firearms education and training platform that integrates AI technology with physical shooting targets to enhanceUnited States$250K

Fintech

8 startups · $532M raised

  1. AcornsAcorns is a global financial wellness app that focuses on micro-investing, helping everyday people and families save and invest smUnited States$438M
  2. AlternativAlternativ is a financial firm that specializes in wealth advisory with a focus on alternative assets.United States$41M
  3. PatientFiPatientFi is a financial technology company based in Irvine, California, that focuses on modernizing healthcare financing.United States$38M
  4. New RangeNew Range is an AI-powered compliance and operations platform tailored for financial markets, specifically broker-dealers and fintUnited States$5.4M
  5. Veri-TaxVeri-Tax is a verification services company based in Irvine, California, specializing in income, employment, and identity verificaUnited States$5.0M
  6. LendAPILendAPI is a fintech infrastructure company based in Irvine, California, founded in 2024.United States$3.2M
  7. DocittDocitt makes the mortgage process simpler, smarter, and safer by eliminating the people, paper, and pain from the loan process.United States$500K
  8. Topflight AppsTopflight Apps is an AI and healthcare product development company based in Irvine, California, founded in 2015.United States$250K

Medical Devices

7 startups · $168M raised

  1. NeomendNeomend is a biomedical device company engaged in the development and commercialization of surgical wound healing products.United States$62M
  2. Breathe TechnologiesBreathe Technologies provide healthcare providers and patients with respiratory therapies that optimize breathing and mobility.United States$39M
  3. AcclarentAcclarent is a medical device company that develops new technologies to treat patients suffering from ENT disorders.United States$35M
  4. ClearFlowClearFlow is a medical device company developing technologies to solve clinical problems associated with obstructed catheters.United States$23M
  5. SurgiCount MedicalSurgiCount Medical offers Safety-Sponge, a solution to increase patient safety and reduce healthcare costs.United States$7.1M
  6. NeurOpticsNeurOptics manufactures devices that gather and process information from the human eye to support medical decision-making and researches.United States$1.7M
  7. AlignMedAlignMed® (Alignmed Inc.) is a California-based company focused on posture correction apparel and Evidence Based Apparel® technology.United States$450K

Proptech

6 startups · $178M raised

  1. Auction.comAuction.com is the largest online marketplace for foreclosure and bank-owned real estate auctions in the United States.United States$142M
  2. Granite Investment GroupGranite Investment Group is a real estate investment firm based in Anaheim Hills, California, active since 1995.United States$13M
  3. QmeritQmerit provides services for EV charger installation, electrification projects, and energy transition solutions.United States$12M
  4. BluonBluon, Inc.United States$6.6M
  5. HomeUnionHomeUnion provides real estate investment management.United States$5.5M
  6. CogniCrewAI virtual employees for commercial real estate, mortgage, and corporate admin, governed, compliant, and ready to work.United States$250K

Big Data & Analytics

6 startups · $62M raised

  1. NGD SystemsNGD Systems manufactures the world’s most advanced computational storage drives (CSDs) that allow customers to compute anywhere.United States$32M
  2. SetScheduleSetSchedule is a technology company that focuses on SAAS, consumer cloud communication, and real estate information products.United States$10M
  3. VisageVisage was a content-creation software company based in Irvine, California, founded around 2012 or 2013.United States$9.2M
  4. OombaOomba is a specialized digital media company bringing elegant organization to sports and games.United States$4.6M
  5. Ubix LabsUbix is an AI-on-demand service that helps users of all skill levels develop and deploy big, fast data architecture and AI pipelines.United States$4.0M
  6. SoteriaSoteria is the leading cloud-based smart retailer CRM company providing real-time analytics, security, and cloud storage service to market.United States$1.4M

How this map is made. Every startup here is based in Irvine and has raised money in rounds we track. Each sits under its main sector, read from its rounds; each sector shows its best-funded first. Rebuilt nightly; updated 15 November 2026.

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