Ecosystem map · Indianapolis

Indianapolis startup ecosystem map

58 startups based in Indianapolis that have raised money in rounds we track, grouped by their main sector. Together they have raised $777M; IT Services is the biggest sector, with 14 companies.

58startups on the map
7sectors
$777Mraised between them
IT Servicesmost funded sector

IT Services

14

Biotech

9

Software

9

Big Data & Analytics

8

Healthtech

7

AI

6

Advertising & Adtech

5

Segment by segment

IT Services

14 startups · $206M raised

  1. AppirioAppirio is an IT technology company providing mobile, social, crowdsourcing, and cloud technology services.United States$116M
  2. TangoeTangoe provides connection lifecycle management software and related services to enterprises and service providers worldwide.United States$26M
  3. KeraunoKerauno is a global Communications Software as a Service (SaaS) and workflow software company based in Indianapolis, Indiana.United States$25M
  4. MetaCXMetaCX provides an outcomes-based approach for managing the entire B2B customer lifecycle.United States$18M
  5. SalesvueSalesvue is a Salesforce-native sales engagement platform that enhances the productivity of sales and marketing teams.United States$6.0M
  6. E-SMARTE-SMART is a technology company that provides software solutions for a safer fleet.United States$4.5M
  7. Perpetual TechnologiesPTI provides infrastructure services, database services, remote DBA services, and other IT solutions for data-driven business entities.United States$4.1M
  8. VontooUtilizing the best in mobile technology: Vontoo offers solutions across various industries ranging from education, entertainment, United States$2.2M

Biotech

9 startups · $198M raised

  1. Syndeio BiosciencesSyndeio Biosciences (from the Ancient Greek word "to connect") is a clinical-stage biotechnology company developing therapies to rUnited States$90M
  2. WWellfountWellfount is a pharmacy offering tech-enabled dispensing to deliver pharmacy services at the point of patient care inside a facility.United States$32M
  3. Strand DiagnosticsStrand Diagnostics develops and markets the know error® system which utilizes bar coding and DNA testing to confirm surgical biopsy samples.United States$30M
  4. NICONICO develops medical devices for minimally invasive neurosurgery, as well as skull base and spinal surgical procedures.United States$29M
  5. hc1The leader in identifying real-time insights and risk signals in complex laboratory data.United States$6.5M
  6. Eskenazi HealthEskenazi Health provides exceptional and comprehensive healthcare to Central Indiana.United States$5.0M
  7. Adipo TherapeuticsAdipo Therapeutics is a biotechnology company located in Indianapolis, Indiana.United States$4.7M
  8. Grannus TherapeuticsGrannus Therapeutics is a biotechnology company that focuses on the development of small molecule inhibitors for specific isoforms of HSP90.United States$800K

Software

9 startups · $49M raised

  1. T2 SystemsT2 Systems provides parking management solutions and services for events.United States$31M
  2. WebLink InternationalWebLink International offers membership management software and web design solutions for associations and chambers of commerce.United States$4.9M
  3. RICS SoftwareRICS Software develops software solutions for the retail market worldwide.United States$4.1M
  4. Ascend IndianaAscend Indiana is a Central Indiana Corporate Partnership (CICP) initiative focused.United States$4.0M
  5. AirwaveAirwave is developer of a push-to-talk mobile application designed to connect people and reduce misinterpretation.United States$3.1M
  6. BloomerangBloomerang is a donor management software company based in Indianapolis, Indiana, dedicated to supporting small and mid-sized nonpUnited States$930K
  7. MMaaguziElectronic Patient Reported OutcomesUnited States$375K
  8. PeoplocityPeoplocity, LLC develops a mobile application that connects consumers in real time with businesses.United States$200K

Big Data & Analytics

8 startups · $110M raised

  1. ZyloZylo is a leading enterprise SaaS management and optimization platform based in Indianapolis, Indiana.United States$40M
  2. EncampEncamp is an enterprise technology company focused on environmental compliance for businesses.United States$30M
  3. AuthenticxAuthenticx is an AI-powered conversation intelligence platform tailored for the healthcare industry.United States$20M
  4. ConverSightConverSight is a privately held SaaS B2B technology company based in Indianapolis, Indiana.United States$9.0M
  5. EntegrataEntegrata is a legal technology company founded in 2023 and based in Carmel, Indiana.United States$4.5M
  6. Stamus NetworksStamus Networks is a provider of high-performance network-based threat detection and hunting systems.United States$3.4M
  7. RootNoteTrack your data, tell your story, and grow.United States$1.5M
  8. SmartFileSmartFile was originally focused on secure file transfer and file-sharing solutions for businesses.United States$1.1M

Healthtech

7 startups · $163M raised

  1. SpectronRxSpectronRx is a specialized radiopharmaceutical Contract Development and Manufacturing Organization (CDMO) founded in 2004, with hUnited States$85M
  2. RenoviaRenovia provides commercial painting, sealants, wood replacement, pressure washing, wet glazing, and tuckpointing services.United States$59M
  3. CORDANT HEALTH SOLUTIONSCordant Health Solutions is a national healthcare and toxicology company focused on monitoring patients in behavioral health, chroUnited States$13M
  4. ETEndGenitor TechnologiesFounded in 2005, EGT combined the pioneering science of Dr.United States$2.5M
  5. Early is GoodEarly is Good is a private healthcare diagnostics company based in Indianapolis, Indiana.United States$1.6M
  6. Plan ForwardPlan Forward is a dental technology company based in Indianapolis/Westfield, Indiana, specializing in membership software for dentUnited States$864K
  7. Compact Medical SolutionsCompact Medical Solutions is a developer of a medical bag-valve-mask used to assist patients with emergency breathing issues.United States$685K

AI

6 startups · $22M raised

  1. Arrive AIArrive AI is a smart Mailbox-as-a-Service infrastructure and platform for autonomous delivery networks.United States$15M
  2. LusterLuster is an AI-powered sales enablement platform based in Indianapolis, Indiana, founded in January 2024.United States$3.0M
  3. BackstrokeBackstroke is a generative AI marketing technology startup founded in 2024 and based in Indianapolis, Indiana.United States$2.8M
  4. BioReactBioReact is a B2B SaaS company based in Indianapolis, Indiana, founded in 2023 by Mitchell Castetter, Joanna Lipinski, and Andrew Chiappetta.United States$1.1M
  5. EkkobarEkkobar is an AI-powered platform based in Boston, Massachusetts, that specializes in Social Decision IntelligenceTM.United States$50K
  6. Invoke LearningInvoke Learning is a higher-education data analytics company that focuses on unifying data from campus systems into a comprehensivUnited States$50K

Advertising & Adtech

5 startups · $30M raised

  1. DemandJumpDemandJump is a customer acquisition software that shows marketers new sources of growth online.United States$14M
  2. PerqPERQ is a digital marketing and marketing automation platform focused on the multifamily rental industry.United States$10M
  3. 250okEmail analytics and deliverability platformUnited States$2.9M
  4. DemandWellDemandwell is a results-driven SEO growth platform tailored for B2B SaaS marketers.United States$1.6M
  5. TetherballTetherball is an advertising company focusing on digital relationship marketing.United States$666K

How this map is made. Every startup here is based in Indianapolis and has raised money in rounds we track. Each sits under its main sector, read from its rounds; each sector shows its best-funded first. Rebuilt nightly; updated 15 November 2026.

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