Ecosystem map · Durham

Durham startup ecosystem map

86 startups based in Durham that have raised money in rounds we track, grouped by their main sector. Together they have raised $1.7B; Biotech is the biggest sector, with 38 companies.

86startups on the map
6sectors
$1.7Braised between them
Biotechmost funded sector

Biotech

38

+14 more

Healthtech

19

IT Services

9

Agtech

8

AI

7

Big Data & Analytics

5

Segment by segment

Biotech

38 startups · $938M raised

  1. HumacyteHumacyte, Inc.United States$297M
  2. Atsena TherapeuticsAtsena Therapeutics is a clinical-stage gene therapy company based in Durham, North Carolina, focused on developing treatments forUnited States$150M
  3. Areteia TherapeuticsAreteia Therapeutics, Inc.United States$75M
  4. IPIdera PharmaceuticalsIdera Pharmaceuticals merged with Aceragen, Inc., a rare disease biopharmaceutical company, in September 2022.United States$54M
  5. RibometrixRibometrix is a platform therapeutics company that discovers small molecule drugs to treat human diseases.United States$45M
  6. SciodermScioderm, a clinical stage pharmaceutical company, develops topical products for the treatment of chronic skin diseases.United States$37M
  7. BiomasonBiomason, Inc.United States$37M
  8. VPVascular PharmaceuticalsVascular Pharmaceuticals engages in the development of therapeutics targeting the treatment of diabetes associated complications.United States$26M

Healthtech

19 startups · $586M raised

  1. BioventusBioventus delivers clinically proven, cost-effective products that help people heal quickly and safely.United States$412M
  2. BaebiesBaebies is a medical device company based in Durham, North Carolina, focused on improving newborn screening and pediatric testing United States$70M
  3. 410 Medical410 Medical is a medical device company dedicated to developing innovative products that enable frontline medical providers to improve care.United States$29M
  4. Bantam PharmaceuticalBantam Pharmaceutical, also known as Bantam Pharma, is a clinical-stage biopharmaceutical company founded in 2015 and based in DurUnited States$25M
  5. PolareanPolarean is manufacturer and service provider for noble gas polarizer devices and ancillary instruments.United States$15M
  6. RevianRevian is the manufacturer and supplier of medical-grade LED technology.United States$13M
  7. AlievioAlievio is an innovative glaucoma medical device company with the mission to alleviate and provide a sense of relief to patients sUnited States$5.7M
  8. ClineticClinetic is a provider of health software and technology services.United States$5.0M

IT Services

9 startups · $24M raised

  1. Automated InsightsAutomated Insights is the creator of Wordsmith, the world’s first public natural language generation platform.United States$12M
  2. ExtellisExtellis is a startup based in Durham, North Carolina, specializing in satellite imagery and Earth observation.United States$6.8M
  3. OperableWe believe that DevOps is a team sport and in order to win more often, we created Cog.United States$2.7M
  4. Resolved AnalyticsResolved Analytics is a product analytics company.United States$978K
  5. CellBreakerCellBreaker allows to easily switch cell phone carriers.United States$396K
  6. EyeQuantEyeQuant is a neuroscience-backed AI company founded in 2009, specializing in predicting user interactions with web and mobile designs.United States$328K
  7. SimpleRegistrySimpleRegistry is changing the way people register for gifts and what they register for!United States$300K
  8. TabSprintTabSprint was a member of The Start-up Factory Spring 2013 class officially incorporating in April 2013.United States$250K

Agtech

8 startups · $79M raised

  1. PairwisePairwise is an agricultural biotechnology company based in Durham, North Carolina, founded in 2017 by Dr.United States$25M
  2. BIOMILQBIOMILQ is a North Carolina-based biotechnology company focused on developing cell-cultured human milk to enhance infant nutrition.United States$21M
  3. Mendel BiotechnologyMendel Biotechnology is a plant biotechnology company that develops genetic and chemical solutions for a range of agricultural markets.United States$20M
  4. Hi Fidelity GeneticsHi Fidelity Genetics is a start up based in Durham, NC.United States$8.5M
  5. EnMass EnergyEnMass Energy is a digital software and procurement platform designed for waste-to-energy and waste-to-value projects.United States$2.2M
  6. De Novo FoodlabsDe Novo Foodlabs is a biotechnology startup founded in 2021, focused on developing animal-free, precision-fermented nutritional solutions.United States$1.5M
  7. Upstream BiotechnologyUpstream Biotechnology, Inc.United States$625K
  8. ScitoVationScitoVation is a biotechnology company that provides technical expertise and technology on pharmaceuticals and agricultural chemicals.United States$270K

AI

7 startups · $51M raised

  1. Keebler HealthKeebler Health is a healthcare technology company based in Durham, North Carolina, founded in 2023.United States$22M
  2. BotBuiltBotBuilt is a construction technology startup based in Durham, North Carolina, founded in 2020.United States$12M
  3. Gradient HealthGradient Health develops an open research platform that offers AI-based medical imaging diagnostics and infrastructure.United States$5.8M
  4. Vega HealthVega Health is a startup based in Durham, North Carolina, founded in October 2025.United States$5.0M
  5. RevelAi HealthRevelAi Health is a conversational and generative AI platform focused on enhancing musculoskeletal (MSK) and orthopedic care.United States$3.1M
  6. Sift MediaSift Media is leveraging advanced AI and machine learning algorithms to hyper-target app install ads for its clients.United States$2.2M
  7. CreoCREO is a management consulting and advisory firm based in Durham, North Carolina, founded in 2015.United States$528K

Big Data & Analytics

5 startups · $10M raised

  1. Resilient BioticsResilient Biotics utilizes big data analytics to design microbiome-based therapeutics and advanced screening methods.United States$7.2M
  2. Enlight ResearchEnlight Research OÜ is a financial research company based in Durham, North Carolina.United States$1.4M
  3. TITransCirrus Inc.Reducing the risk, cost and complexity of the journey to the cloud by leveraging an OpenStack cloud in a box appliance solution.United States$750K
  4. biospatialbiospatial is a platform that analyzes healthcare data to support the missions of public sector and commercial healthcare entities.United States$710K
  5. Geometric Data AnalyticsGeometric Data Analytics is a research, development and consulting company.United States$200K

How this map is made. Every startup here is based in Durham and has raised money in rounds we track. Each sits under its main sector, read from its rounds; each sector shows its best-funded first. Rebuilt nightly; updated 15 November 2026.

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