Ecosystem map · Chicago

Chicago startup ecosystem map

352 startups based in Chicago that have raised money in rounds we track, grouped by their main sector. Together they have raised $15B; Healthtech is the biggest sector, with 47 companies.

352startups on the map
12sectors
$15Braised between them
Healthtechmost funded sector

Healthtech

47

+23 more

IT Services

47

+23 more

AI

44

+20 more

Fintech

43

+19 more

Advertising & Adtech

29

+5 more

Biotech

27

+3 more

Software

21

Foodtech

21

Big Data & Analytics

21

Edtech

19

Web3 & Crypto

17

Internet

16

Segment by segment

Healthtech

47 startups · $7.8B raised

  1. VillageMDVillageMD is a national primary care platform based in Chicago, Illinois, founded in 2013.United States$6.9B
  2. Oak Street HealthOak Street Health is a network of primary care centers for adults on Medicare.United States$340M
  3. Zing HealthZing Health offers Medicare advantage plans that enhances healthcare access and include supplemental benefits.United States$140M
  4. DxTx Pain and SpineDxTx Pain and Spine is a healthcare practice management firm that operates a network of around 60 interventional pain and spine prUnited States$50M
  5. ArtisightArtisight is a healthcare technology company based in Chicago, Illinois, founded in 2017 by clinician Andrew Gostine and technologUnited States$42M
  6. KalderosKalderos provides a SaaS based drug discount management solution, which identifies, checks, and resolves non-compliance.United States$33M
  7. CylinderCylinder is a digital health company that offers personalized care for people with digestive conditions.United States$31M
  8. Atraverse MedicalAtraverse Medical offers a product development for left-heart access technology to simplify workflows and improve patient outcomes.United States$29M

IT Services

47 startups · $935M raised

  1. NerdioNerdio is a Microsoft ISV with deep expertise in its cloud technologies such as Azure Virtual Desktop, Windows 365 and Intune.United States$500M
  2. RightpointRightpoint is an independent customer experience agency with technology at our core.United States$55M
  3. ShiftgigShiftgig is a workforce technology company based in Chicago, Illinois, that specializes in software solutions for staffing agencieUnited States$55M
  4. HireologyHireology is a talent acquisition and hiring technology company based in Chicago, Illinois.United States$53M
  5. Bswiftbswift LLC offers cloud-based technology and services that transform the way employees perceive and engage with their benefits.United States$51M
  6. CatalyticCatalytic is a Chicago-based company that specializes in no-code workflow and intelligent automation software.United States$36M
  7. PartsTrader LLCPartsTrader LLC is a cloud-based parts procurement platform designed for the collision repair industry.United States$30M
  8. JellyvisionJellyvision, officially known as The Jellyvision Lab, Inc., is a Chicago-based SaaS company that specializes in interactive employUnited States$25M

AI

44 startups · $883M raised

  1. OcientOcient is a data analytics software solutions company based in Chicago, Illinois, founded in 2016.United States$200M
  2. ChowbusChowbus is a full-stack restaurant technology company and food delivery platform based in Chicago, Illinois.United States$105M
  3. EvozyneEvozyne is a biotechnology company based in Chicago, Illinois, focused on designing and developing innovative protein therapeuticsUnited States$81M
  4. HealthJoyHealthJoy is a healthcare technology company based in Chicago, founded in 2014.United States$73M
  5. ThreekitThreekit is an AI-powered Visual Commerce Platform based in Chicago, Illinois.United States$65M
  6. Narrative ScienceNarrative Science creates software that writes stories from enterprise data to drive understanding and results.United States$49M
  7. Letter AILetter AI is an innovative revenue enablement platform founded in 2023 by Ali Akhtar and Armen Forget, based in Chicago, Illinois.United States$43M
  8. Empirical SecurityEmpirical builds mathematical models for security data.United States$37M

Fintech

43 startups · $2.7B raised

  1. OnDeckOndeck is a technology-enabled financial platform that provides loan financing to small and medium-sized businesses.United States$538M
  2. Kin InsuranceKin Insurance is an insurtech company that offers personalized home insurance policies.United States$513M
  3. Aequum CapitalAequum is a commercial business that integrates an Environmental, Social, and Governance investment ethos.United States$250M
  4. HighTower AdvisorsHightower Advisors is an independent wealth management and financial planning firm based in Chicago, Illinois.United States$200M
  5. AmountAmount is a digital technology company that accelerates digital transformation for financial institutions.United States$159M
  6. Braviant HoldingsA leading provider of tech-enabled credit products and services for underbanked consumersUnited States$150M
  7. BonsideBonside is a capital provider specializing in non-dilutive, revenue-based financing for brick-and-mortar businesses with three or United States$100M
  8. Halo InvestingHalo Investing is a financial technology platform based in Chicago, co-founded in 2015 by Biju Kulathakal and Jason Barsema.United States$100M

Advertising & Adtech

29 startups · $255M raised

  1. DialogTechDialogTech provides actionable marketing analytics for businesses that value phone calls.United States$77M
  2. Leapfrog OnlineLeapfrog Online is a digital direct marketing firm and performance marketing agency based in Evanston, Illinois.United States$30M
  3. UPshowUPshow is transforming what people experience on the shared televisions of the worldUnited States$18M
  4. ChowlyChowly provides innovative tech solutions to connect restaurant POS platforms with third-party online ordering solutions.United States$16M
  5. BzzAgentBzzAgent helps the world’s largest brands engage everyday influencers to drive sales.United States$15M
  6. Popular PaysPopular Pays is a platform that connects brands with creators who make content worth sharing.United States$13M
  7. CMDTYCMDTY specializes in delivering data, analytical tools and workflow solutions that drive sustainability in the area of agriculture markets.United States$10M
  8. YesmailYes Lifecycle Marketing provides solutions that orchestrate cross-channel marketing communications to drive results and revenue.United States$9.0M

Biotech

27 startups · $1.4B raised

  1. Outcome HealthOutcome Health is a prominent healthcare technology company based in Chicago, Illinois, focused on enhancing patient care through United States$600M
  2. Nature's FyndNature's Fynd is a Chicago-based food-tech company that specializes in creating animal-free meat and dairy alternatives.United States$350M
  3. Vanqua BioVanqua Bio is a biopharmaceutical company based in Chicago, founded in 2019.United States$130M
  4. NPNeuroTherapeutics PharmaNeuroTherapeutics Pharma is a biopharmaceutical company developing new therapies to treat pain, epilepsy, and other nervous system disorder.United States$58M
  5. EviveEvive seamlessly integrates benefits into the lives of more than 4 million people every day.United States$47M
  6. Meitheal PharmaceuticalsMeitheal Pharmaceuticals specializes in research, manufacturing, and supply of injection medicine.United States$35M
  7. MAIA BiotechnologyMAIA Biotechnology is a clinical-stage biopharmaceutical company developing cancer therapies that target telomeres through immunotherapy.United States$30M
  8. EmmausEMMAUS is an NGO that fights to end trafficking, prevent exploitation and empower male survivors of the sex trade to rebuild their lives.United States$30M

Software

21 startups · $259M raised

  1. SpringCMSpringCM is a secure document and contract management platform used to solve critical business needs.United States$105M
  2. SittercitySittercity's mission is to make child care finally work.United States$48M
  3. InContext SolutionsInContext Solutions is the global leader in enterprise mixed reality (MR) solutions for total retail optimization and shopper engagement.United States$21M
  4. MediaflyMediafly offers a revenue enablement platform for enterprise B2B teams.United States$20M
  5. EvedGlobal AP & Payments Platform for Events, Media and Entertainment.United States$11M
  6. INXPOINXPO helps brands interact with employees, customers, prospects and partners in a social environment by creating a two-way dialogue.United States$10M
  7. RocketmilesRocketmiles is a startup that lets travelers earn frequent flier miles in major airline programs when booking hotel stays through its site.United States$8.5M
  8. Conduit LabsDevelopment tools platform for connected devicesUnited States$8.5M

Foodtech

21 startups · $170M raised

  1. FeastablesFeastables is a snacking brand founded by YouTuber Jimmy Donaldson, known as MrBeast, in 2021.United States$60M
  2. CannCann is a developer of data analytics and digital menu solutions mainly created for businesses in the cannabis industry.United States$27M
  3. 86 Repairs86 Repairs is a subscription service platform that manages end-to-end equipment repair and maintenance for restaurants.United States$19M
  4. Heaven's DoorHeaven's Door Spirits is a premium American whiskey brand co-founded by musician Bob Dylan and the Chicago-based Spirits InvestmenUnited States$14M
  5. TovalaTovala is a Chicago-based food-tech company that combines a smart countertop oven with a meal delivery service.United States$9.2M
  6. KadeyaKadeya is a closed-loop water vending business that utilizes digitally connected reusable water bottles and tiny bottling equipment.United States$9.1M
  7. Pilot Project BrewingPilot Project Brewing is a brewery incubator and tasting room located in Chicago, Illinois, with an additional facility in MilwaukUnited States$7.7M
  8. Aisle50Aisle50 came out of the summer 2011 class at Y Combinator, the Silicon Valley accelerator.United States$5.2M

Big Data & Analytics

21 startups · $238M raised

  1. Civis AnalyticsCivis Analytics is a data science software and consultancy company based in Chicago, founded in 2013 by Dan Wagner.United States$53M
  2. PriceLabsPriceLabs is a provider of dynamic pricing and revenue management solutions for the short-term rental industry.United States$30M
  3. Grove BiopharmaGrove Biopharma is a preclinical biotechnology company based in Chicago, Illinois, founded in 2020 as a spinout from Northwestern University.United States$30M
  4. Label InsightLabel Insight is a SaaS company that provides insights on food label data to government, retailers, manufacturers and app developers.United States$21M
  5. DataForgeDataForge is a Chicago-based software company founded in 2023, specializing in a declarative data management platform.United States$20M
  6. Network PerceptionNetwork Perception provides a network device configuration analysis software to visualize and verify their network architecture.United States$13M
  7. definityDefinity is an AI-powered data engineering platform that specializes in observability, remediation, and optimization for LakehouseUnited States$12M
  8. ModelOpModelOp is an enterprise software company that specializes in Model Operations (ModelOps), AI governance, and lifecycle managementUnited States$10M

Edtech

19 startups · $192M raised

  1. BenchPrepBenchPrep is a Chicago-based technology company that specializes in cloud-based educational software and adaptive learning platforms.United States$30M
  2. CodeacademyCode Academy is an immersive three-month program for passionate people who want to learn how to build web applications.United States$30M
  3. WayUpWayUp connects students with jobs during and after college -- from summer internships to part-time gigs to full-time jobs after graduation.United States$27M
  4. Elevate K-12Elevate K-12 is an instructional services company that provides live streaming instruction to K-12 classrooms.United States$25M
  5. ThinkCERCAThinkCERCA is a Chicago-based education technology company that specializes in a personalized, AI-enabled literacy platform for K-United States$15M
  6. CertiverseCertiverse is an AI-powered certification platform based in Chicago, Illinois, founded in 2019.United States$11M
  7. HaparaHapara provides visible and differentiated instructional management tools for educators using Goole Workspace and Google ClassroomUnited States$11M
  8. CodeverseCodeverse is a kids' coding education company that provides an engaging platform for children aged 6 to 13 to learn coding.United States$10M

Web3 & Crypto

17 startups · $135M raised

  1. PortalPortal helps you impress your clients by turning around comprehensive.United States$48M
  2. BitnomialBitnomial offers improved derivatives exchange technology coupled with new digital asset settlement systems.United States$25M
  3. Pi SquaredPi Squared enables trustless remote computing, AI, and interoperable smart contracts for any blockchain or dApp.United States$13M
  4. Yield ProtocolYield Protocol is a decentralized finance (DeFi) platform that focuses on fixed-rate, fixed-term borrowing and lending for digital assets.United States$10M
  5. GigaStarGigaStar is a fintech platform based in Wilmette, Illinois, founded in 2022.United States$6.0M
  6. TapiocaDAOTapiocaDAO is a decentralized autonomous organization (DAO) focused on the development of full-link decentralized financial (DeFi) products.United States$6.0M
  7. Meme.comMeme.com is a technology and Web3 company founded in 2021, focused on a platform dedicated to memes.United States$5.0M
  8. Ion ProtocolIon Protocol is a lending protocol that accepts pledged and re-pledged assets, allowing users to deposit any validator-backed asset.United States$4.8M

Internet

16 startups · $125M raised

  1. PowerReviewsPowerReviews is a provider of ratings, reviews and question and answer technology for brands and retailers.United States$75M
  2. SSidewalkSidewalk assists small businesses with internet data collection to allow them to target their core audience.United States$24M
  3. BridesideBrideside is a manufacturer and online retailer of bridesmaid gowns and swatches for women.United States$12M
  4. WWhittlWhittl is an online platform to book appointments with salons, spas, dentists, barber shops and other local businesses.United States$4.6M
  5. WinestyrWinestyr is a direct-to-consumer wine marketplace that connects consumers with artisanal wineries across America.United States$3.0M
  6. OfficeLuvOfficeLuv creates happier and more productive workplaces by centralizing office ordering through one platform.United States$2.5M
  7. LOLocal Offer NetworkLocal Offer Network connects data sources to present the right content for visitors.United States$1.5M
  8. DDishableThink about how many times you’ve had this conversation: “Where do you want to eat tonight?” “I don’t know.United States$1.1M

How this map is made. Every startup here is based in Chicago and has raised money in rounds we track. Each sits under its main sector, read from its rounds; each sector shows its best-funded first. Rebuilt nightly; updated 15 November 2026.

More market maps

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Market map · ChicagoFood tech market map: Chicago17 startups · 3 segments · $583MMarket map · ChicagoFintech market map: Chicago13 startups · 3 segments · $1.2BMarket mapMarketing tech market map1,963 startups · 7 segments · $41BMarket mapFintech market map1,633 startups · 8 segments · $139BMarket mapCrypto and Web3 market map1,297 startups · 8 segments · $33BMarket mapFood tech market map1,226 startups · 7 segments · $20B

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