Market map · United States

AI drug discovery market map: United States

87 AI drug discovery startups based in the United States that have raised money in rounds we track, placed in 4 segments by what each says it does. Together they have raised $5.5B; the biggest segment is AI discovery platforms.

87startups on the map
4segments
$5.5Braised between them
AI discovery platformsmost funded segment

AI discovery platforms

51

+27 more

Small molecules

17

Protein design

12

Antibodies and biologics

7

Segment by segment

AI discovery platforms

51 startups · $2.7B raised

  1. Xaira TherapeuticsXaira Therapeutics is an integrated biotechnology company founded in 2023 and publicly launched in April 2024.United States$1.0B
  2. EnvedaEnveda Biosciences is a clinical-stage biotechnology company founded in 2019, focused on accelerating drug discovery through an AIUnited States$461M
  3. Recursion PharmaceuticalsRecursion Pharmaceuticals is a biotech company that develops a drug discovery platform and pipeline with machine learning.United States$339M
  4. Terray TherapeuticsTerray Therapeutics is a biotechnology company that propels drug discovery into the information age.United States$145M
  5. Zephyr AIZephyr AI is a precision medicine and healthcare technology company focused on enhancing drug discovery and clinical trials througUnited States$111M
  6. Jnana TherapeuticsJnana Therapeutics develops innovative therapies using a chemoproteomics drug discovery platform.United States$107M
  7. ValthosValthos is a New York-based biodefense startup founded in September 2024 by Kathleen McMahon and Tess van Stekelenburg.United States$57M
  8. Belharra TherapeuticsBelharra Therapeutics disrupts the drug discovery paradigm with its novel photoaffinity-based chemoproteomics platform.United States$50M

Small molecules

17 startups · $1.0B raised

  1. Terremoto BiosciencesTerremoto Biosciences is a clinical-stage biotechnology company founded in 2021, focused on covalent drug discovery and development.United States$283M
  2. AtomwiseAtomwise is a technology-enabled pharmaceutical company that focuses on small-molecule drug discovery using deep learning.United States$97M
  3. QuantX BiosciencesQuantX Biosciences is a biotechnology company that specializes in computational drug discovery and small-molecule therapeutic products.United States$85M
  4. Exo TherapeuticsExo Therapeutics, Inc.United States$78M
  5. Nimbus TherapeuticsNimbus Therapeutics is a clinical-stage biotechnology company based in Boston, Massachusetts, founded in 2009.United States$72M
  6. Excelsior SciencesExcelsior Sciences is a biotechnology company based in New York City, founded in 2024.United States$70M
  7. Light Horse TherapeuticsLight Horse Therapeutics, Inc.United States$62M
  8. Kimia TherapeuticsKimia Therapeutics, Inc.United States$55M

Protein design

12 startups · $1.5B raised

  1. Relay TherapeuticsRelay therapeutics is a developer of an allosteric drug-discovery platform intended to apply computational techniques to protein motion.United States$932M
  2. SepternaSepterna is a biotech firm unlocking diverse drug discovery potential in G protein-coupled receptors across various diseases.United States$150M
  3. Outpace BioOutpace Bio is a clinical-stage biotechnology company based in Seattle, Washington.United States$144M
  4. CellarityCellarity is a biotechnology therapeutics company based in Somerville, Massachusetts, founded in 2017 by Flagship Pioneering.United States$121M
  5. GRO BiosciencesGRO Biosciences, also known as GRObio, is a biotechnology company based in Cambridge, Massachusetts, founded in 2016.United States$87M
  6. ArzedaWe harness the power of Intelligent Protein Design TechnologyTM to create enzyme products solving industry's toughest challengesUnited States$65M
  7. X-37X-37 is a private drug discovery and development company based in South San Francisco, California.United States$15M
  8. Cyrus BiotechnologyCyrus Biotechnology is a Seattle-based biotechnology company founded in 2014, focusing on AI-driven protein design and screening tUnited States$10M

Antibodies and biologics

7 startups · $162M raised

  1. Enable MedicineEnable medicine is a biotechnology company that develops biological cartography tools to generate cellular maps that help in drug discovery.United States$60M
  2. Metaphore BiotechnologiesMetaphore Biotechnologies is a biotechnology company based in Cambridge, Massachusetts, founded in 2021 by Flagship Pioneering.United States$50M
  3. Tahoe TherapeuticsTahoe Therapeutics is a biotechnology company based in South San Francisco, California.United States$30M
  4. OwkinOwkin is a French-American TechBio company that focuses on advancing biopharma research and development through its innovative BioUnited States$11M
  5. Prellis BiologicsPrellis Biologics is a biotechnology company based in Berkeley, California, focused on advancing drug discovery.United States$8.7M
  6. Algorithmic BiologicsAlgorithmic Biologics is a Bengaluru-based startup founded in March 2021 by Dr.United States$2.5M
  7. Macromoltek IncMacromoltek Inc.United States$120K

How this map is made. Every startup here has raised money in rounds we track, and is based in United States. It joins the map when its sectors, read from its rounds, or the opening of its own description say it works in AI drug discovery, and goes to the first segment whose words it carries. Each segment shows its best-funded first. Rebuilt nightly; updated 15 November 2026.

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