United States · Funded startup

Who invested in Actuate Therapeutics

2 rounds we have observed, with the 4 investors named in them. Every figure came from a named source, and where the company reported a raise to the SEC itself, that is shown beside it.

BiotechHealthcare

Raised 12 months ago

Funding summaryUpdated 26 Oct 2026

$122Mraised across 2 rounds since 2019, from 2 sources

$22MSeries B$100MRound
Latest round
Round, $100MNov 2025
Step-upi
4.6×
Investors
4 (1 led)
See who backed them

The funding story

Each circle is a round, placed by date and sized by amount. The line above is the running total.

2019202020212022202320242025
$22MSeries B$100MRound
First round
Series B, $22M
May 2019
Biggest round
$100M
Round · Nov 2025
Between rounds
6.5 years
from the last two

The rounds

  1. Nov 2025
    Round$100M1 returning

    Source recordedSEC filing: $4.7M sold, first sale Jun 2025

  2. May 2019
    Series B$22M4 new

    Reported by FinSMEsSEC filing: $22M sold, first sale Apr 2019

Founders and team

From Actuate Therapeutics's own website: 9 on the team.

  • Daniel M. SchmittPresident & Chief Executive Officer
  • Chris SeifarthVice President, Operations and Quality Assurance
  • Paul LytleChief Financial Officer
  • Amy RonnebergDirector
  • Carrie KellingerSenior Director, Operations
  • Jason KeyesDirector
  • Roger SawhneyDirector
  • Sarah MajkaSenior Manager, Clinical Operations
  • Todd ThomsonDirector

Who was in which round

The busiest backers across the latest rounds. A filled square is a round they joined; a dark one, a round they led.

Everyone who backed them

Tech Coast AngelsVC firm2rounds
Kairos VenturesVC firm1round, led 1
DEFTA PartnersVC firm1round
Bios PartnersPrivate equity1round

Missing a round, or an investor who was in one? Tell us.

Also claim to have backed them

These 2 firms list Actuate Therapeutics as a portfolio company on their own websites, but no report of a round names them. They are the firms' own claims, kept apart from the rounds above.

Illinois VenturesGovernmentPer its own site
SeedFolioVC firmPer its own site

Quick answers about Actuate Therapeutics

Who invested in Actuate Therapeutics?

Actuate Therapeutics's investors include Tech Coast Angels, Kairos Ventures, DEFTA Partners and Bios Partners.

How much has Actuate Therapeutics raised?

Actuate Therapeutics has raised $122M across 2 rounds since 2019.

When did Actuate Therapeutics last raise?

Actuate Therapeutics's most recent round was an Undisclosed round of $100M in Nov 2025.

What was Actuate Therapeutics's biggest round?

Its most recent round, $100M in Nov 2025, is also its largest on record.

Who backed Actuate Therapeutics first?

Actuate Therapeutics's first round on record, in May 2019, was backed by Kairos Ventures, Tech Coast Angels and DEFTA Partners and 1 others.

What stage is Actuate Therapeutics at?

Actuate Therapeutics's latest named round is an Undisclosed round, in Nov 2025.

Where is Actuate Therapeutics based?

Actuate Therapeutics is based in the United States.

Who led Actuate Therapeutics's rounds?

Kairos Ventures led the Series B in 2019.

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