# Top 50 Startups in Waltham by Funding (2026) > The 50 best-funded startups in Waltham, ranked by total funding raised: $12B combined. With founding year, headquarters and each company's rounds. Source: https://millionrounds.com/top-lists/startups-waltham (Millionrounds; every figure on the page links to its filing or article) - 1 [**Devoted Health** Devoted Health is a technology-driven healthcare company founded in 2017 by brothers Todd and Ed Park.](https://millionrounds.com/company/devoted-health) Devoted Health is a technology-driven healthcare company founded in 2017 by brothers Todd and Ed Park. *Founded* 2017 Waltham, United States **$2.1B** last round Nov 2026 - 2 [**Oruka Therapeutics** Oruka Therapeutics is advancing innovative biologics to redefine patient care standards in chronic skin diseases.](https://millionrounds.com/company/oruka-therapeutics) Oruka Therapeutics is advancing innovative biologics to redefine patient care standards in chronic skin diseases. *Founded* - Waltham, United States **$880M** last round Apr 2026 - 3 [**Dyne Therapeutics** Dyne Therapeutics is a developer of targeted therapies intended for serious muscle diseases.](https://millionrounds.com/company/dyne-therapeutics) Dyne Therapeutics is a developer of targeted therapies intended for serious muscle diseases. *Founded* 2018 Waltham, United States **$828M** last round Jul 2026 - 4 [**Dianthus Therapeutics** Dianthus Therapeutics is a biotech company developing new treatments for serious autoimmune diseases using a more targeted approach.](https://millionrounds.com/company/dianthus-therapeutics) Dianthus Therapeutics is a biotech company developing new treatments for serious autoimmune diseases using a more targeted approach. *Founded* 2019 Waltham, United States **$719M** last round Mar 2026 - 5 [**Next Insurance** Next Insurance is a digital insurance company specializing in coverage for entrepreneurs and small businesses.](https://millionrounds.com/company/next-insurance) Next Insurance is a digital insurance company specializing in coverage for entrepreneurs and small businesses. *Founded* 2016 Waltham, United States **$627M** last round Nov 2023 - 6 [**Kailera Therapeutics** Kailera Therapeutics develops next-generation injectable and oral therapies for chronic weight management.](https://millionrounds.com/company/kailera-therapeutics) Kailera Therapeutics develops next-generation injectable and oral therapies for chronic weight management. *Founded* - Waltham, United States **$600M** last round Oct 2025 - 7 [**ElevateBio** ElevateBio is a biotechnology company based in Waltham, Massachusetts, founded in 2017.](https://millionrounds.com/company/elevatebio) ElevateBio is a biotechnology company based in Waltham, Massachusetts, founded in 2017. *Founded* 2017 Waltham, United States **$551M** last round May 2023 - 8 [**Korsana Biosciences** Korsana Biosciences develops THETA-enabled antibody therapies for neurodegenerative diseases including Alzheimer’s.](https://millionrounds.com/company/korsana-biosciences) Korsana Biosciences develops THETA-enabled antibody therapies for neurodegenerative diseases including Alzheimer’s. *Founded* - Waltham, United States **$530M** last round Sept 2026 - 9 [**Zenas BioPharma** Zenas BioPharma is a biopharmaceutical company that focuses on developing immune-based therapies for patients.](https://millionrounds.com/company/zenas-biopharma) Zenas BioPharma is a biopharmaceutical company that focuses on developing immune-based therapies for patients. *Founded* 2023 Waltham, United States **$420M** last round Mar 2026 - 10 [**Morphic Therapeutic** Morphic Therapeutic is a biotechnology company that develops oral integrin therapies to treat serious chronic diseases.](https://millionrounds.com/company/morphic-therapeutic) Morphic Therapeutic is a biotechnology company that develops oral integrin therapies to treat serious chronic diseases. *Founded* 2015 Waltham, United States **$328M** last round May 2023 - 11 [**Markforged** Markforged is a manufacturing company that invents a new 3D printing process to build parts with the strength of Continuous Carbon Fiber.](https://millionrounds.com/company/markforged) Markforged is a manufacturing company that invents a new 3D printing process to build parts with the strength of Continuous Carbon Fiber. *Founded* 2013 Waltham, United States **$323M** last round Jul 2021 - 12 [**Actifio** Actifio delivers enterprise data-as-a-service to global enterprise customers and service provider partners.](https://millionrounds.com/company/actifio) Actifio delivers enterprise data-as-a-service to global enterprise customers and service provider partners. *Founded* 2009 Waltham, United States **$308M** last round Aug 2018 - 13 [**Upstream Bio** Upstream Bio focuses on developing an antibody therapy for the treatment of severe asthma.](https://millionrounds.com/company/upstream-bio) Upstream Bio focuses on developing an antibody therapy for the treatment of severe asthma. *Founded* 2021 Waltham, United States **$200M** last round Jun 2023 - 14 [**BostonGene** BostonGene is a biotechnology company based in Waltham, Massachusetts, founded in 2015.](https://millionrounds.com/company/bostongene) BostonGene is a biotechnology company based in Waltham, Massachusetts, founded in 2015. *Founded* 2015 Waltham, United States **$200M** last round Apr 2022 - 15 [**Cogent Biosciences** Cogent Biosciences is a biotechnology company that develops therapies for solid cancer tumors.](https://millionrounds.com/company/cogent-biosciences) Cogent Biosciences is a biotechnology company that develops therapies for solid cancer tumors. *Founded* 2014 Waltham, United States **$200M** last round Nov 2025 - 16 [**Jade Biosciences** Jade Biosciences is developing transformative therapies to redefine the standard of care for inflammation and immunology indications.](https://millionrounds.com/company/jade-biosciences) Jade Biosciences is developing transformative therapies to redefine the standard of care for inflammation and immunology indications. *Founded* - Waltham, United States **$195M** last round Jun 2026 - 17 [**CallMiner** CallMiner provides solutions for analyzing and extracting insights from customer interactions, particularly in call centers.](https://millionrounds.com/company/callminer) CallMiner provides solutions for analyzing and extracting insights from customer interactions, particularly in call centers. *Founded* 2002 Waltham, United States **$155M** last round Jun 2025 - 18 [**Skyhawk Therapeutics** Skyhawk Therapeutics is a clinical-stage biotechnology company located in Waltham, Massachusetts.](https://millionrounds.com/company/skyhawk-therapeutics) Skyhawk Therapeutics is a clinical-stage biotechnology company located in Waltham, Massachusetts. *Founded* 2016 Waltham, United States **$133M** last round Sept 2021 - 19 [**Deciphera Pharmaceuticals** Deciphera Pharmaceuticals focuses on improving kinase inhibitor treatments.](https://millionrounds.com/company/deciphera-pharmaceuticals) Deciphera Pharmaceuticals focuses on improving kinase inhibitor treatments. *Founded* 2003 Waltham, United States **$127M** last round Jun 2017 - 20 [**Invivyd** Invivyd develops antibodies to transcend the limitations of the human immune system and fight against viral infections.](https://millionrounds.com/company/invivyd) Invivyd develops antibodies to transcend the limitations of the human immune system and fight against viral infections. *Founded* 2020 Waltham, United States **$125M** last round Nov 2025 - 21 [**Visterra** Visterra researches on and develops therapeutic and diagnostic products for the treatment of infectious diseases.](https://millionrounds.com/company/visterra) Visterra researches on and develops therapeutic and diagnostic products for the treatment of infectious diseases. *Founded* 2007 Waltham, United States **$120M** last round Oct 2017 - 22 [**Scipher Medicine** Scipher Medicine develops a healthcare platform designed to determine which drug will work best for each patient.](https://millionrounds.com/company/scipher-medicine) Scipher Medicine develops a healthcare platform designed to determine which drug will work best for each patient. *Founded* 2014 Waltham, United States **$110M** last round Feb 2022 - 23 [**Koura** Koura is a global leader in the development, manufacture, and supply of fluoro products.](https://millionrounds.com/company/koura) Koura is a global leader in the development, manufacture, and supply of fluoro products. *Founded* 2011 Waltham, United States **$100M** last round Oct 2022 - 24 [**Palleon Pharmaceuticals** Palleon Pharmaceuticals is a clinical-stage biotechnology company based in Waltham, Massachusetts.](https://millionrounds.com/company/palleon-pharmaceuticals) Palleon Pharmaceuticals is a clinical-stage biotechnology company based in Waltham, Massachusetts. *Founded* 2016 Waltham, United States **$100M** last round Sept 2020 - 25 [**CounterTack** CounterTack is a cybersecurity company based in Waltham, Massachusetts, with additional offices in California and Singapore.](https://millionrounds.com/company/countertack) CounterTack is a cybersecurity company based in Waltham, Massachusetts, with additional offices in California and Singapore. *Founded* 2011 Waltham, United States **$97M** last round May 2017 - 26 [**Infinidat** Infinidat's portfolio of primary and secondary storage platforms provides best-in-class performance with guaranteed 100% availability, built in InfiniSafe®️ cyb](https://millionrounds.com/company/infinidat) Infinidat's portfolio of primary and secondary storage platforms provides best-in-class performance with guaranteed 100% availability, built in InfiniSafe®️ cyb *Founded* 2011 Waltham, United States **$95M** last round Oct 2017 - 27 [**Evolv Technology** Evolv Technology an AI-enabled touchless security screening system that uses digital sensors and artificial intelligence to detect threats.](https://millionrounds.com/company/evolv-technology) Evolv Technology an AI-enabled touchless security screening system that uses digital sensors and artificial intelligence to detect threats. *Founded* 2013 Waltham, United States **$93M** last round Jul 2025 - 28 [**Rocket Software** Rocket Software is a software development firm that offers enterprise infrastructure products and various related services.](https://millionrounds.com/company/rocket-software) Rocket Software is a software development firm that offers enterprise infrastructure products and various related services. *Founded* 1990 Waltham, United States **$92M** last round Oct 2009 - 29 [**Artisan Pharma** Artisan Pharma is a Hospital and Health Care company located in 230 Third Avenue, Waltham, MA, United States.](https://millionrounds.com/company/artisan-pharma) Artisan Pharma is a Hospital and Health Care company located in 230 Third Avenue, Waltham, MA, United States. *Founded* 2006 Waltham, United States **$85M** last round Jul 2010 - 30 [**Incipient** Incipient software allows for: * Non-Disruptive, On-Line Data Migration * Network Volume Management * Storage Provisioning * Copy Services With Incipient softwa](https://millionrounds.com/company/incipient) Incipient software allows for: * Non-Disruptive, On-Line Data Migration * Network Volume Management * Storage Provisioning * Copy Services With Incipient softwa *Founded* 2001 Waltham, United States **$85M** last round Feb 2008 - 31 [**TScan Therapeutics** TScan Therapeutics is a biopharmaceutical company focused on the development of immunotherapy treatments for cancer.](https://millionrounds.com/company/tscan-therapeutics) TScan Therapeutics is a biopharmaceutical company focused on the development of immunotherapy treatments for cancer. *Founded* 2018 Waltham, United States **$78M** last round Dec 2024 - 32 [**Exosome Diagnostics** Exosome Diagnostics develops and commercializes blood-based cancer molecular diagnostics for patient stratification and disease monitoring.](https://millionrounds.com/company/exosome-diagnostics) Exosome Diagnostics develops and commercializes blood-based cancer molecular diagnostics for patient stratification and disease monitoring. *Founded* 2008 Waltham, United States **$76M** last round Sept 2015 - 33 [**Photys Therapeutics** Photys Therapeutics is a biotechnology and pharmaceutical research company founded in 2021 and based in Waltham, Massachusetts.](https://millionrounds.com/company/photys-therapeutics) Photys Therapeutics is a biotechnology and pharmaceutical research company founded in 2021 and based in Waltham, Massachusetts. *Founded* 2021 Waltham, United States **$75M** last round Sept 2022 - 34 [**Eloxx** Eloxx Pharmaceuticals is a clinical-stage biopharmaceutical company developing novel RNA-modulating drug candidates.](https://millionrounds.com/company/eloxx) Eloxx Pharmaceuticals is a clinical-stage biopharmaceutical company developing novel RNA-modulating drug candidates. *Founded* 2013 Waltham, United States **$66M** last round Jun 2026 - 35 [**Yottaa** Yottaa is a cloud-based eCommerce performance and security company based in Waltham, Massachusetts.](https://millionrounds.com/company/yottaa) Yottaa is a cloud-based eCommerce performance and security company based in Waltham, Massachusetts. *Founded* 2009 Waltham, United States **$63M** last round Oct 2018 - 36 [**Orionis Biosciences** Orionis Biosciences is a clinical-stage life sciences company based in Waltham, Massachusetts, with a research facility in Ghent, Belgium.](https://millionrounds.com/company/orionis-biosciences) Orionis Biosciences is a clinical-stage life sciences company based in Waltham, Massachusetts, with a research facility in Ghent, Belgium. *Founded* 2015 Waltham, United States **$59M** last round Oct 2022 - 37 [**Immunitas Therapeutics** Immunitas Therapeutics is a clinical-stage biopharmaceutical company founded in 2019, focused on discovering and developing novel antibody-based therapeutics fo](https://millionrounds.com/company/immunitas-therapeutics) Immunitas Therapeutics is a clinical-stage biopharmaceutical company founded in 2019, focused on discovering and developing novel antibody-based therapeutics fo *Founded* 2019 Waltham, United States **$58M** last round Aug 2021 - 38 [**Instylla** Instylla is a medical equipment supplier that provides liquid embolics of the next generation for interventional radiology.](https://millionrounds.com/company/instylla) Instylla is a medical equipment supplier that provides liquid embolics of the next generation for interventional radiology. *Founded* 2017 Waltham, United States **$56M** last round Jul 2026 - 39 [**Linus Health** Linus Health is a digital health company focused on improving mental health and brain health by using screening technology.](https://millionrounds.com/company/linus-health) Linus Health is a digital health company focused on improving mental health and brain health by using screening technology. *Founded* 2019 Waltham, United States **$55M** last round Jul 2021 - 40 [**Convergent Dental** Convergent Dental develops a computer-guided, laser-based drilling, and cutting system for dentists.](https://millionrounds.com/company/convergent-dental) Convergent Dental develops a computer-guided, laser-based drilling, and cutting system for dentists. *Founded* 2011 Waltham, United States **$52M** last round Apr 2023 - 41 [**Great Elm Capital** Great Elm Capital is a business development company that invests in the debt instruments of middle-market companies.](https://millionrounds.com/company/great-elm-capital) Great Elm Capital is a business development company that invests in the debt instruments of middle-market companies. *Founded* - Waltham, United States **$50M** last round Sept 2025 - 42 [**Humatics** Humatics is a technology company based in Waltham, Massachusetts, founded in 2015.](https://millionrounds.com/company/humatics) Humatics is a technology company based in Waltham, Massachusetts, founded in 2015. *Founded* 2015 Waltham, United States **$46M** last round Jun 2023 - 43 [**Vecna Robotics** Vecna Robotics, Inc.](https://millionrounds.com/company/vecna-robotics) Vecna Robotics, Inc. *Founded* 1998 Waltham, United States **$46M** last round Sept 2026 - 44 [**Sojournix** Sojournix is a clinical-stage pharmaceutical company that researches and develops novel therapeutics for the treatment of neuroendocrine disorders.](https://millionrounds.com/company/sojournix) Sojournix is a clinical-stage pharmaceutical company that researches and develops novel therapeutics for the treatment of neuroendocrine disorders. *Founded* 2016 Waltham, United States **$44M** last round Jan 2019 - 45 [**NanoMosaic** NanoMosaic provides solutions for early illness detection, prognostic monitoring, and biomarker identification.](https://millionrounds.com/company/nanomosaic) NanoMosaic provides solutions for early illness detection, prognostic monitoring, and biomarker identification. *Founded* 2018 Waltham, United States **$44M** last round Nov 2025 - 46 [**Xilio Therapeutics** Xilio Therapeutics is a biotechnology company that develops tumor-activated immuno-oncology therapies.](https://millionrounds.com/company/xilio-therapeutics) Xilio Therapeutics is a biotechnology company that develops tumor-activated immuno-oncology therapies. *Founded* 2020 Waltham, United States **$40M** last round Feb 2026 - 47 [**Affinia Therapeutics** Affinia Therapeutics is a preclinical-stage biotechnology company based in Waltham, Massachusetts, founded in 2019.](https://millionrounds.com/company/affinia-therapeutics) Affinia Therapeutics is a preclinical-stage biotechnology company based in Waltham, Massachusetts, founded in 2019. *Founded* 2019 Waltham, United States **$40M** last round Oct 2025 - 48 [**Cazena** Cazena, Inc is a Massachusetts based company delivering fully-managed Big Data as a Service](https://millionrounds.com/company/cazena) Cazena, Inc is a Massachusetts based company delivering fully-managed Big Data as a Service *Founded* 2014 Waltham, United States **$38M** last round Jul 2020 - 49 [**Boston Dynamics** Boston Dynamics builds advanced mobile manipulation robots with remarkable mobility, dexterity perception and agility.](https://millionrounds.com/company/boston-dynamics) Boston Dynamics builds advanced mobile manipulation robots with remarkable mobility, dexterity perception and agility. *Founded* 1992 Waltham, United States **$37M** last round Feb 2019 - 50 [**Augmenix** SpaceOAR designs, develops and commercializes hydrogel based medical devices for radiation oncology, urology and cancer surgery.](https://millionrounds.com/company/augmenix) SpaceOAR designs, develops and commercializes hydrogel based medical devices for radiation oncology, urology and cancer surgery. *Founded* 2007 Waltham, United States **$36M** last round Jul 2014 **Total funding** how the list is ranked **15 November 2026** updated nightly **Rounds we track** source: Millionrounds Every startup we hold in Waltham, ranked by the total it has raised in rounds we hold. Nobody pays to be on a list. ## Who backed them? Open any company for its rounds and investors, or search the investors who back startups in Waltham in the app, with filters, lists and exports. [Find their investors](https://millionrounds.com/login?join=1&next=/app/investors)[All top lists](https://millionrounds.com/top-lists) ## More startup lists [See all](https://millionrounds.com/top-lists?t=All%20startups) [*O* *A* *X* **Startups in the United States** 42,176 companies · $870B](https://millionrounds.com/top-lists/startups-united-states)[*SC* *N* *F* **Startups in the United Kingdom** 8,355 companies · $79B](https://millionrounds.com/top-lists/startups-united-kingdom)[*O* *D* *TM* **Startups in San Francisco** 4,251 companies · $350B](https://millionrounds.com/top-lists/startups-san-francisco)[*W* *K* *P* **Startups in New York** 3,729 companies · $67B](https://millionrounds.com/top-lists/startups-new-york)[*F* *IL* *PD* **Startups in London** 3,521 companies · $51B](https://millionrounds.com/top-lists/startups-london)[*MA* *M* *TE* **Startups in France** 3,025 companies · $32B](https://millionrounds.com/top-lists/startups-france)[*C* *H8* *AP* **Startups in Canada** 2,950 companies · $38B](https://millionrounds.com/top-lists/startups-canada)[*B* *D* *AF* **Startups in China** 2,168 companies · $163B](https://millionrounds.com/top-lists/startups-china) ## More lists for Waltham [See all](https://millionrounds.com/top-lists?r=Waltham) [*OT* *DT* *KT* **Biotech startups in Waltham** 37 companies · $5.6B](https://millionrounds.com/top-lists/biotech-startups-waltham)[*DH* *DT* *KT* **Healthcare startups in Waltham** 17 companies · $5.2B](https://millionrounds.com/top-lists/healthcare-startups-waltham)[*RS* *I* *Y* **IT Services startups in Waltham** 13 companies · $360M](https://millionrounds.com/top-lists/it-services-startups-waltham)