# Top 50 Startups in South San Francisco by Funding (2026) > The 50 best-funded startups in South San Francisco, ranked by total funding raised: $14B combined. With founding year, headquarters and each company's rounds. Source: https://millionrounds.com/top-lists/startups-south-san-francisco (Millionrounds; every figure on the page links to its filing or article) - 1 [**Verily** Learn how Verily's AI-native data platform unifies complex health data with robust governance, accelerating research and care to deliver real-world impact for p](https://millionrounds.com/company/verily) Learn how Verily's AI-native data platform unifies complex health data with robust governance, accelerating research and care to deliver real-world impact for p *Founded* - South San Francisco, United States **$1.3B** last round Mar 2026 - 2 [**Xaira Therapeutics** Xaira Therapeutics is an integrated biotechnology company founded in 2023 and publicly launched in April 2024.](https://millionrounds.com/company/xaira-therapeutics) Xaira Therapeutics is an integrated biotechnology company founded in 2023 and publicly launched in April 2024. *Founded* 2023 South San Francisco, United States **$1.0B** last round Apr 2024 - 3 [**Structure Therapeutics** Structure Therapeutics specializes in the discovery and development of drugs against a type of targets called GPCR.](https://millionrounds.com/company/structure-therapeutics) Structure Therapeutics specializes in the discovery and development of drugs against a type of targets called GPCR. *Founded* 2016 South San Francisco, United States **$748M** last round Dec 2025 - 4 [**NewLimit** NewLimit is a biotechnology company based in South San Francisco, California, focused on extending human healthspan through innovative medicines that restore yo](https://millionrounds.com/company/newlimit) NewLimit is a biotechnology company based in South San Francisco, California, focused on extending human healthspan through innovative medicines that restore yo *Founded* 2022 South San Francisco, United States **$610M** last round Jun 2026 - 5 [**IDEAYA Biosciences** IDEAYA Biosciences is an oncology-focused biotechnology company that develops therapeutics for patients with genetically-defined cancers.](https://millionrounds.com/company/ideaya-biosciences) IDEAYA Biosciences is an oncology-focused biotechnology company that develops therapeutics for patients with genetically-defined cancers. *Founded* 2015 South San Francisco, United States **$608M** last round Jun 2026 - 6 [**Freenome** Freenome is a biotechnology company with a comprehensive multiomics platform for cancer detection using a routine blood draw.](https://millionrounds.com/company/freenome) Freenome is a biotechnology company with a comprehensive multiomics platform for cancer detection using a routine blood draw. *Founded* 2014 South San Francisco, United States **$553M** last round Jul 2026 - 7 [**ArsenalBio** ArsenalBio is a programmable cell therapy company that offers advanced CAR T-cell therapies for solid tumors.](https://millionrounds.com/company/arsenalbio) ArsenalBio is a programmable cell therapy company that offers advanced CAR T-cell therapies for solid tumors. *Founded* 2019 South San Francisco, United States **$410M** last round Sept 2024 - 8 [**Global Blood Therapeutics** GBT is a clinical-stage biopharmaceutical company developing a therapy for sickle cell disease.](https://millionrounds.com/company/global-blood-therapeutics) GBT is a clinical-stage biopharmaceutical company developing a therapy for sickle cell disease. *Founded* 2011 South San Francisco, United States **$389M** last round Dec 2021 - 9 [**Encoded Therapeutics** Encoded Therapeutics is a Harnessing the regulatory genome to create next-generation molecular therapies.](https://millionrounds.com/company/encoded-therapeutics) Encoded Therapeutics is a Harnessing the regulatory genome to create next-generation molecular therapies. *Founded* 2014 South San Francisco, United States **$379M** last round Sept 2026 - 10 [**Pliant Therapeutics** Pliant Therapeutics focuses on discovering, developing, and commercializing breakthrough treatments for fibrotic diseases.](https://millionrounds.com/company/pliant-therapeutics) Pliant Therapeutics focuses on discovering, developing, and commercializing breakthrough treatments for fibrotic diseases. *Founded* 2015 South San Francisco, United States **$350M** last round Jan 2023 - 11 [**NGM Biopharmaceuticals** NGM Biopharmaceuticals Inc.](https://millionrounds.com/company/ngm-biopharmaceuticals) NGM Biopharmaceuticals Inc. *Founded* 2008 South San Francisco, United States **$333M** last round Mar 2015 - 12 [**Tricida** Tricida operates in the healthcare industry focusing on pharmaceutical business.](https://millionrounds.com/company/tricida) Tricida operates in the healthcare industry focusing on pharmaceutical business. *Founded* 2013 South San Francisco, United States **$327M** last round Oct 2022 - 13 [**Star Therapeutics** Star Therapeutics is a clinical-stage biotechnology company based in South San Francisco, California, founded in 2018.](https://millionrounds.com/company/star-therapeutics) Star Therapeutics is a clinical-stage biotechnology company based in South San Francisco, California, founded in 2018. *Founded* 2018 South San Francisco, United States **$325M** last round Oct 2026 - 14 [**Allogene Therapeutics** Allogene Therapeutics is a biotechnology company catalyzing cancer treatment through the development of CAR T therapy.](https://millionrounds.com/company/allogene-therapeutics) Allogene Therapeutics is a biotechnology company catalyzing cancer treatment through the development of CAR T therapy. *Founded* 2017 South San Francisco, United States **$310M** last round Apr 2026 - 15 [**Maze Therapeutics** Maze Therapeutics is an operator of a biotechnology firm used to focus on translating genetic insights into new medicines.](https://millionrounds.com/company/maze-therapeutics) Maze Therapeutics is an operator of a biotechnology firm used to focus on translating genetic insights into new medicines. *Founded* 2018 South San Francisco, United States **$300M** last round Apr 2026 - 16 [**Terremoto Biosciences** Terremoto Biosciences is a clinical-stage biotechnology company founded in 2021, focused on covalent drug discovery and development.](https://millionrounds.com/company/terremoto-biosciences) Terremoto Biosciences is a clinical-stage biotechnology company founded in 2021, focused on covalent drug discovery and development. *Founded* 2021 South San Francisco, United States **$283M** last round Apr 2026 - 17 [**Glydways** Glydways, Inc.](https://millionrounds.com/company/glydways) Glydways, Inc. *Founded* 2016 South San Francisco, United States **$271M** last round Apr 2026 - 18 [**Vera Therapeutics** Vera Therapeutics is a biotechnology company developing innovative biologic therapeutics with transformative clinical potential.](https://millionrounds.com/company/vera-therapeutics) Vera Therapeutics is a biotechnology company developing innovative biologic therapeutics with transformative clinical potential. *Founded* 2016 South San Francisco, United States **$261M** last round Dec 2025 - 19 [**Surrozen** Surrozen is a biopharmaceutical that focuses on unlocking the body’s regenerative power to treat injury and disease.](https://millionrounds.com/company/surrozen) Surrozen is a biopharmaceutical that focuses on unlocking the body’s regenerative power to treat injury and disease. *Founded* 2015 South San Francisco, United States **$258M** last round Mar 2025 - 20 [**Cellares** Cellares is a biotechnology company based in South San Francisco, California, and is recognized as the world’s first Integrated Development and Manufacturing Or](https://millionrounds.com/company/cellares) Cellares is a biotechnology company based in South San Francisco, California, and is recognized as the world’s first Integrated Development and Manufacturing Or *Founded* 2019 South San Francisco, United States **$257M** last round Jan 2026 - 21 [**Rapt Therapeutics** Rapt is focused on the discovery and development of novel small-molecule agents to activate the immune system to eradicate cancer.](https://millionrounds.com/company/rapt-therapeutics) Rapt is focused on the discovery and development of novel small-molecule agents to activate the immune system to eradicate cancer. *Founded* 2015 South San Francisco, United States **$250M** last round Oct 2025 - 22 [**ORIC Pharmaceuticals** ORIC Pharmaceuticals is a biopharmaceutical company that develops treatments that target the causes of therapeutic resistance.](https://millionrounds.com/company/oric-pharmaceuticals) ORIC Pharmaceuticals is a biopharmaceutical company that develops treatments that target the causes of therapeutic resistance. *Founded* 2014 South San Francisco, United States **$248M** last round May 2025 - 23 [**Nkarta Therapeutics** Nkarta Therapeutics is a developer of cell engineering platform created to build the next generation of cell therapies.](https://millionrounds.com/company/nkarta-therapeutics) Nkarta Therapeutics is a developer of cell engineering platform created to build the next generation of cell therapies. *Founded* 2015 South San Francisco, United States **$240M** last round Mar 2024 - 24 [**Plenty** Plenty® is an American farming technology company specializing in indoor vertical farming.](https://millionrounds.com/company/plenty) Plenty® is an American farming technology company specializing in indoor vertical farming. *Founded* 2013 South San Francisco, United States **$225M** last round May 2024 - 25 [**InterVenn** InterVenn unlocks the glycoproteome using artificial intelligence for the development of transformational healthcare solutions in DX and Rx.](https://millionrounds.com/company/intervenn) InterVenn unlocks the glycoproteome using artificial intelligence for the development of transformational healthcare solutions in DX and Rx. *Founded* 2017 South San Francisco, United States **$210M** last round Aug 2021 - 26 [**Soley Therapeutics** Soley Therapeutics is a biotechnology company based in South San Francisco, California, focused on drug discovery and development.](https://millionrounds.com/company/soley-therapeutics) Soley Therapeutics is a biotechnology company based in South San Francisco, California, focused on drug discovery and development. *Founded* 2020 South San Francisco, United States **$200M** last round Jan 2026 - 27 [**Circle Pharma** Circle Pharma is a provider of a macrocycle development platform intended to provide macrocyclic peptides.](https://millionrounds.com/company/circle-pharma) Circle Pharma is a provider of a macrocycle development platform intended to provide macrocyclic peptides. *Founded* 2012 South San Francisco, United States **$187M** last round Sept 2026 - 28 [**Electra Therapeutics** Electra Therapeutics is a clinical-stage biotechnology company based in South San Francisco, California, founded in 2018.](https://millionrounds.com/company/electra-therapeutics) Electra Therapeutics is a clinical-stage biotechnology company based in South San Francisco, California, founded in 2018. *Founded* 2018 South San Francisco, United States **$183M** last round Oct 2025 - 29 [**Lycia Therapeutics** Lycia Therapeutics is a clinical-stage biotechnology company based in South San Francisco, California.](https://millionrounds.com/company/lycia-therapeutics) Lycia Therapeutics is a clinical-stage biotechnology company based in South San Francisco, California. *Founded* 2020 South San Francisco, United States **$182M** last round Jun 2026 - 30 [**Annexon Biosciences** Annexon Biosciences is a biotech company, discovering and developing novel therapeutics for neurodegenerative and autoimmune disorders.](https://millionrounds.com/company/annexon-biosciences) Annexon Biosciences is a biotech company, discovering and developing novel therapeutics for neurodegenerative and autoimmune disorders. *Founded* - South San Francisco, United States **$180M** last round Jul 2026 - 31 [**Day One Biopharmaceuticals** Day One Biopharmaceuticals develops targeted therapies to treat people with life-threatening diseases.](https://millionrounds.com/company/day-one-biopharmaceuticals) Day One Biopharmaceuticals develops targeted therapies to treat people with life-threatening diseases. *Founded* 2018 South San Francisco, United States **$175M** last round Jul 2024 - 32 [**Senti Biosciences** Senti Biosciences is a biotechnology company that focuses on synthetic biology and gene circuit engineering for therapeutic applications.](https://millionrounds.com/company/senti-biosciences) Senti Biosciences is a biotechnology company that focuses on synthetic biology and gene circuit engineering for therapeutic applications. *Founded* 2016 South San Francisco, United States **$169M** last round May 2026 - 33 [**Solazyme** Solazyme is a synthetic biology company converting algal biomass into biofuels for the transportation, cosmetic and food industries.](https://millionrounds.com/company/solazyme) Solazyme is a synthetic biology company converting algal biomass into biofuels for the transportation, cosmetic and food industries. *Founded* 2003 South San Francisco, United States **$146M** last round Aug 2010 - 34 [**Harpoon Therapeutics** Harpoon Therapeutics is a clinical-stage immunotherapy company focused on the development of novel T-cell recruiting biologic therapies.](https://millionrounds.com/company/harpoon-therapeutics) Harpoon Therapeutics is a clinical-stage immunotherapy company focused on the development of novel T-cell recruiting biologic therapies. *Founded* 2015 South San Francisco, United States **$145M** last round Oct 2023 - 35 [**True North Therapeutics** True North Therapeutics is a pioneering biotechnology company selectively inhibiting the Complement pathway for diseases.](https://millionrounds.com/company/true-north-therapeutics) True North Therapeutics is a pioneering biotechnology company selectively inhibiting the Complement pathway for diseases. *Founded* 2013 South San Francisco, United States **$142M** last round Jan 2018 - 36 [**Nura Bio** Nura Bio is a clinical-stage biopharmaceutical company based in South San Francisco, California.](https://millionrounds.com/company/nura-bio) Nura Bio is a clinical-stage biopharmaceutical company based in South San Francisco, California. *Founded* 2018 South San Francisco, United States **$142M** last round Jun 2026 - 37 [**Quince Therapeutics** Quince Therapeutics is developing treatments for Alzheimer's and other degenerative disorders.](https://millionrounds.com/company/quince-therapeutics) Quince Therapeutics is developing treatments for Alzheimer's and other degenerative disorders. *Founded* 2012 South San Francisco, United States **$137M** last round May 2026 - 38 [**Moonwalk Biosciences** Moonwalk Biosciences is an early-stage, pre-clinical therapeutics company based in South San Francisco, California, with an additional office in San Diego.](https://millionrounds.com/company/moonwalk-biosciences) Moonwalk Biosciences is an early-stage, pre-clinical therapeutics company based in South San Francisco, California, with an additional office in San Diego. *Founded* 2022 South San Francisco, United States **$127M** last round Sept 2026 - 39 [**Quanta Therapeutics** Quanta Therapeutics, Inc.](https://millionrounds.com/company/quanta-therapeutics) Quanta Therapeutics, Inc. *Founded* 2018 South San Francisco, United States **$127M** last round Jun 2026 - 40 [**SonoThera** SonoThera is a biotechnology company based in South San Francisco that focuses on developing ultrasound-guided, nonviral gene therapies.](https://millionrounds.com/company/sonothera) SonoThera is a biotechnology company based in South San Francisco that focuses on developing ultrasound-guided, nonviral gene therapies. *Founded* 2021 South San Francisco, United States **$125M** last round Jun 2026 - 41 [**AKASA** AKASA is a HealthTech company that specializes in generative AI-powered automation solutions for the healthcare revenue cycle.](https://millionrounds.com/company/akasa) AKASA is a HealthTech company that specializes in generative AI-powered automation solutions for the healthcare revenue cycle. *Founded* 2019 South San Francisco, United States **$120M** last round Jun 2024 - 42 [**Hana Biosciences** Talon Therapeutics is a biopharmaceutical company develops and commercializes new and differentiated cancer therapies.](https://millionrounds.com/company/hana-biosciences) Talon Therapeutics is a biopharmaceutical company develops and commercializes new and differentiated cancer therapies. *Founded* 2002 South San Francisco, United States **$116M** last round Jun 2010 - 43 [**Calithera Biosciences** Calithera Biosciences is a pharmaceutical company developing novel small molecule therapeutics for the treatment of cancer.](https://millionrounds.com/company/calithera-biosciences) Calithera Biosciences is a pharmaceutical company developing novel small molecule therapeutics for the treatment of cancer. *Founded* 2010 South San Francisco, United States **$115M** last round Mar 2022 - 44 [**Trace Neuroscience** Launched in 2024, Trace Neuroscience is a biopharmaceutical company on a mission to expand the promise of genomic medicine for people living with neurodegenerat](https://millionrounds.com/company/trace-neuroscience) Launched in 2024, Trace Neuroscience is a biopharmaceutical company on a mission to expand the promise of genomic medicine for people living with neurodegenerat *Founded* 2024 South San Francisco, United States **$101M** last round Nov 2024 - 45 [**Addition Therapeutics** Addition Therapeutics develops RNA-only therapeutics using PRINT technology for genetic medicine.](https://millionrounds.com/company/addition-therapeutics) Addition Therapeutics develops RNA-only therapeutics using PRINT technology for genetic medicine. *Founded* - South San Francisco, United States **$100M** last round Dec 2025 - 46 [**Lyell Immunopharma** Lyell Immunopharma is an operator of a biotechnology company that develops cellular therapies to cure cancer.](https://millionrounds.com/company/lyell-immunopharma) Lyell Immunopharma is an operator of a biotechnology company that develops cellular therapies to cure cancer. *Founded* 2018 South San Francisco, United States **$100M** last round Jul 2025 - 47 [**Genome Medical** Genome Medical is a telegenomics technology and services company allowing access to genomic-based medicine.](https://millionrounds.com/company/genome-medical) Genome Medical is a telegenomics technology and services company allowing access to genomic-based medicine. *Founded* 2016 South San Francisco, United States **$98M** last round Sept 2024 - 48 [**Epicrispr Biotechnologies** Epicrispr Biotechnologies is a clinical-stage biotechnology company based in South San Francisco, California.](https://millionrounds.com/company/epicrispr-biotechnologies) Epicrispr Biotechnologies is a clinical-stage biotechnology company based in South San Francisco, California. *Founded* 2018 South San Francisco, United States **$90M** last round Aug 2026 - 49 [**Principia BioPharma** Principia Biopharma is dedicated to bringing oral therapies to patients with significant unmet medical needs in immunology & oncology.](https://millionrounds.com/company/principia-biopharma) Principia Biopharma is dedicated to bringing oral therapies to patients with significant unmet medical needs in immunology & oncology. *Founded* 2008 South San Francisco, United States **$90M** last round Aug 2015 - 50 [**Kezar Life Sciences** Kezar Life Sciences company focused on the discovery and development of drugs targeting protein homeostasis for autoimmune disorders](https://millionrounds.com/company/kezar-life-sciences) Kezar Life Sciences company focused on the discovery and development of drugs targeting protein homeostasis for autoimmune disorders *Founded* 2015 South San Francisco, United States **$85M** last round Oct 2022 **Total funding** how the list is ranked **15 November 2026** updated nightly **Rounds we track** source: Millionrounds Every startup we hold in South San Francisco, ranked by the total it has raised in rounds we hold. Nobody pays to be on a list. ## Who backed them? Open any company for its rounds and investors, or search the investors who back startups in South San Francisco in the app, with filters, lists and exports. [Find their investors](https://millionrounds.com/login?join=1&next=/app/investors)[All top lists](https://millionrounds.com/top-lists) ## More startup lists [See all](https://millionrounds.com/top-lists?t=All%20startups) [*O* *A* *X* **Startups in the United States** 42,176 companies · $870B](https://millionrounds.com/top-lists/startups-united-states)[*SC* *N* *F* **Startups in the United Kingdom** 8,355 companies · $79B](https://millionrounds.com/top-lists/startups-united-kingdom)[*O* *D* *TM* **Startups in San Francisco** 4,251 companies · $350B](https://millionrounds.com/top-lists/startups-san-francisco)[*W* *K* *P* **Startups in New York** 3,729 companies · $67B](https://millionrounds.com/top-lists/startups-new-york)[*F* *IL* *PD* **Startups in London** 3,521 companies · $51B](https://millionrounds.com/top-lists/startups-london)[*MA* *M* *TE* **Startups in France** 3,025 companies · $32B](https://millionrounds.com/top-lists/startups-france)[*C* *H8* *AP* **Startups in Canada** 2,950 companies · $38B](https://millionrounds.com/top-lists/startups-canada)[*B* *D* *AF* **Startups in China** 2,168 companies · $163B](https://millionrounds.com/top-lists/startups-china) ## More lists for South San Francisco [See all](https://millionrounds.com/top-lists?r=South%20San%20Francisco) [*V* *ST* *N* **Biotech startups in South San Francisco** 81 companies · $12B](https://millionrounds.com/top-lists/biotech-startups-south-san-francisco)[*V* *F* *A* **Healthcare startups in South San Francisco** 31 companies · $5.9B](https://millionrounds.com/top-lists/healthcare-startups-south-san-francisco)[*V* *XT* *I* **AI startups in South San Francisco** 16 companies · $2.9B](https://millionrounds.com/top-lists/ai-startups-south-san-francisco)[*NB* *MT* *OP* **Pharma startups in South San Francisco** 10 companies · $1.3B](https://millionrounds.com/top-lists/pharma-startups-south-san-francisco)