# Top 50 Startups in San Diego by Funding (2026) > The 50 best-funded startups in San Diego, ranked by total funding raised: $20B combined. With founding year, headquarters and each company's rounds. Source: https://millionrounds.com/top-lists/startups-san-diego (Millionrounds; every figure on the page links to its filing or article) - 1 [**Shield AI** Shield AI is an artificial intelligence company that aims to protect service members and civilians with intelligent systems.](https://millionrounds.com/company/shield-ai) Shield AI is an artificial intelligence company that aims to protect service members and civilians with intelligent systems. *Founded* 2015 San Diego, United States **$7.0B** last round Nov 2026 - 2 [**Candid Therapeutics** Candid Therapeutics was a clinical-stage biotechnology company based in San Diego, California, founded in 2024.](https://millionrounds.com/company/candid-therapeutics) Candid Therapeutics was a clinical-stage biotechnology company based in San Diego, California, founded in 2024. *Founded* 2024 San Diego, United States **$875M** last round Mar 2026 - 3 [**Avidity Biosciences** Synapse Energy Economics is a consulting firm providing economic and policy analysis for the electric power sector.](https://millionrounds.com/company/avidity-biosciences) Synapse Energy Economics is a consulting firm providing economic and policy analysis for the electric power sector. *Founded* 2012 San Diego, United States **$790M** last round Sept 2025 - 4 [**Maxwell Power** Maxwell Power is a renewable energy company that installs solar panels.](https://millionrounds.com/company/maxwell-power) Maxwell Power is a renewable energy company that installs solar panels. *Founded* - San Diego, United States **$750M** last round Jun 2026 - 5 [**Erasca** Erasca is a developer of oncology drugs intended to provide precision oncology options.](https://millionrounds.com/company/erasca) Erasca is a developer of oncology drugs intended to provide precision oncology options. *Founded* 2018 San Diego, United States **$739M** last round Jul 2026 - 6 [**Lytx** Lytx develops video-based driver safety and fleet management solutions.](https://millionrounds.com/company/lytx) Lytx develops video-based driver safety and fleet management solutions. *Founded* 1998 San Diego, United States **$700M** last round Apr 2018 - 7 [**Viking Therapeutics** Viking Therapeutics is developing novel therapeutics for patients suffering from metabolic and endocrine disorders.](https://millionrounds.com/company/viking-therapeutics) Viking Therapeutics is developing novel therapeutics for patients suffering from metabolic and endocrine disorders. *Founded* 2012 San Diego, United States **$635M** last round Feb 2024 - 8 [**Gossamer Bio** Gossamer Bio is a biopharmaceutical company focused on the discovery and development of novel and differentiated therapeutic products.](https://millionrounds.com/company/gossamer-bio) Gossamer Bio is a biopharmaceutical company focused on the discovery and development of novel and differentiated therapeutic products. *Founded* 2015 San Diego, United States **$567M** last round Sept 2026 - 9 [**Applied Data Finance** ADF has been purpose-built to be the optimal link between the underestimated underbanked consumer and capital markets.](https://millionrounds.com/company/applied-data-finance) ADF has been purpose-built to be the optimal link between the underestimated underbanked consumer and capital markets. *Founded* 2014 San Diego, United States **$539M** last round Mar 2026 - 10 [**ClickUp** ClickUp is a productivity and work management platform that consolidates various tools into a single workspace.](https://millionrounds.com/company/clickup) ClickUp is a productivity and work management platform that consolidates various tools into a single workspace. *Founded* 2017 San Diego, United States **$525M** last round Jul 2025 - 11 [**Cybereason** Cybereason is an endpoint detection and response platform that identifies cyber attacks for effective response.](https://millionrounds.com/company/cybereason) Cybereason is an endpoint detection and response platform that identifies cyber attacks for effective response. *Founded* 2012 San Diego, United States **$509M** last round Mar 2025 - 12 [**Cidara Therapeutics** Cidara Therapeutics is a biotechnology company that specializes in the fields of healthcare and therapeutics.](https://millionrounds.com/company/cidara-therapeutics) Cidara Therapeutics is a biotechnology company that specializes in the fields of healthcare and therapeutics. *Founded* 2012 San Diego, United States **$463M** last round Oct 2025 - 13 [**Artiva Biotherapeutics** Artiva Biotherapeutics is a biotech company focused on developing and commercializing allogeneic natural killer (NK) cell therapies.](https://millionrounds.com/company/artiva-biotherapeutics) Artiva Biotherapeutics is a biotech company focused on developing and commercializing allogeneic natural killer (NK) cell therapies. *Founded* 2019 San Diego, United States **$420M** last round May 2026 - 14 [**Belite Bio** Belite Bio is a clinical stage biopharmaceutical drug development company.](https://millionrounds.com/company/belite-bio) Belite Bio is a clinical stage biopharmaceutical drug development company. *Founded* 2018 San Diego, United States **$350M** last round Dec 2025 - 15 [**Kyriba** Kyriba is a leader in liquidity performance and SaaS treasury solutions, helping CFOs, Treasurers, and IT leaders manage and optimize their liquidity in complex](https://millionrounds.com/company/kyriba) Kyriba is a leader in liquidity performance and SaaS treasury solutions, helping CFOs, Treasurers, and IT leaders manage and optimize their liquidity in complex *Founded* 2000 San Diego, United States **$251M** last round Mar 2019 - 16 [**Mirador Therapeutics** Mirador Therapeutics is a clinical-stage precision medicine company based in San Diego, California.](https://millionrounds.com/company/mirador-therapeutics) Mirador Therapeutics is a clinical-stage precision medicine company based in San Diego, California. *Founded* 2024 San Diego, United States **$250M** last round Jan 2026 - 17 [**Wiliot** Wiliot is a startup based in Caesarea, Israel, with a business development presence in San Diego, US.](https://millionrounds.com/company/wiliot) Wiliot is a startup based in Caesarea, Israel, with a business development presence in San Diego, US. *Founded* 2017 San Diego, United States **$235M** last round Jul 2021 - 18 [**Poseida Therapeutics** Poseida Therapeutics is a biopharmaceutical company utilizing gene engineering capabilities to develop targeted therapeutics.](https://millionrounds.com/company/poseida-therapeutics) Poseida Therapeutics is a biopharmaceutical company utilizing gene engineering capabilities to develop targeted therapeutics. *Founded* 2014 San Diego, United States **$217M** last round Aug 2023 - 19 [**Genomatica** Genomatica manufactures sustainable chemicals from renewable feedstocks.](https://millionrounds.com/company/genomatica) Genomatica manufactures sustainable chemicals from renewable feedstocks. *Founded* 2000 San Diego, United States **$203M** last round Oct 2018 - 20 [**Drata** Drata is a compliance and security SaaS platform that automates the compliance workflows on a company's security controls.](https://millionrounds.com/company/drata) Drata is a compliance and security SaaS platform that automates the compliance workflows on a company's security controls. *Founded* 2020 San Diego, United States **$200M** last round Dec 2022 - 21 [**Element Biosciences** Element Biosciences is a biotechnology company based in San Diego, founded in 2017 by former Illumina scientists.](https://millionrounds.com/company/element-biosciences) Element Biosciences is a biotechnology company based in San Diego, founded in 2017 by former Illumina scientists. *Founded* 2017 San Diego, United States **$190M** last round Jun 2026 - 22 [**ViaCyte** ViaCyte is a cellular therapy and regenerative medicine company based in San Diego, California.](https://millionrounds.com/company/viacyte) ViaCyte is a cellular therapy and regenerative medicine company based in San Diego, California. *Founded* - San Diego, United States **$188M** last round Nov 2018 - 23 [**aTyr Pharma** aTyr Pharma (Nasdaq: LIFE) is a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel biological pathways.](https://millionrounds.com/company/atyr-pharma) aTyr Pharma (Nasdaq: LIFE) is a biotherapeutics company engaged in the discovery and development of innovative medicines based on novel biological pathways. *Founded* - San Diego, United States **$181M** last round Mar 2015 - 24 [**Capstan Therapeutics** Capstan Therapeutics is advancing cell engineering to develop therapeutics for a broad range of diseases.](https://millionrounds.com/company/capstan-therapeutics) Capstan Therapeutics is advancing cell engineering to develop therapeutics for a broad range of diseases. *Founded* 2021 San Diego, United States **$175M** last round Mar 2024 - 25 [**IQHQ** IQHQ is a commercial real estate developer that specializes in creating and developing effective environments and innovative homes.](https://millionrounds.com/company/iqhq) IQHQ is a commercial real estate developer that specializes in creating and developing effective environments and innovative homes. *Founded* 2019 San Diego, United States **$170M** last round Aug 2025 - 26 [**Epic Sciences** Epic Sciences is a diagnostics company improving cancer management by providing real-time biopsy material to guide personalized medicine.](https://millionrounds.com/company/epic-sciences) Epic Sciences is a diagnostics company improving cancer management by providing real-time biopsy material to guide personalized medicine. *Founded* 2008 San Diego, United States **$165M** last round Apr 2023 - 27 [**Cloudbeds** Cloudbeds is a cloud-based hospitality management system (HMS) and property management system (PMS) that streamlines hotel operations, guest experiences, and re](https://millionrounds.com/company/cloudbeds) Cloudbeds is a cloud-based hospitality management system (HMS) and property management system (PMS) that streamlines hotel operations, guest experiences, and re *Founded* 2012 San Diego, United States **$162M** last round Nov 2021 - 28 [**RayzeBio** RayzeBio is a pharmaceuticals company that develops targeted radiopharmaceutical drugs for cancer.](https://millionrounds.com/company/rayzebio) RayzeBio is a pharmaceuticals company that develops targeted radiopharmaceutical drugs for cancer. *Founded* 2018 San Diego, United States **$160M** last round Sept 2022 - 29 [**Engrail Therapeutics** Engrail Therapeutics is a clinical-stage pharmaceutical company based in San Diego, California, founded in 2019.](https://millionrounds.com/company/engrail-therapeutics) Engrail Therapeutics is a clinical-stage pharmaceutical company based in San Diego, California, founded in 2019. *Founded* 2019 San Diego, United States **$157M** last round Mar 2024 - 30 [**Suneva Medical** Suneva Medical, Inc.](https://millionrounds.com/company/suneva-medical) Suneva Medical, Inc. *Founded* 2009 San Diego, United States **$155M** last round Jun 2016 - 31 [**3D Robotics** 3DR makes advanced drone technology easily accessible to the construction, mining, and surveying industries for use in data analysis.](https://millionrounds.com/company/3d-robotics) 3DR makes advanced drone technology easily accessible to the construction, mining, and surveying industries for use in data analysis. *Founded* 2009 San Diego, United States **$152M** last round Apr 2017 - 32 [**Cerulean Pharma** Cerulean Pharma develops nanotechnology-based therapeutics for treating oncology, cardiovascular, autoimmune and inflammatory diseases.](https://millionrounds.com/company/cerulean-pharma) Cerulean Pharma develops nanotechnology-based therapeutics for treating oncology, cardiovascular, autoimmune and inflammatory diseases. *Founded* 2006 San Diego, United States **$152M** last round Apr 2015 - 33 [**SDRE Homebuyers** SDRE Homebuyers is a real estate investment firm providing property development, property management, and real estate services.](https://millionrounds.com/company/sdre-homebuyers) SDRE Homebuyers is a real estate investment firm providing property development, property management, and real estate services. *Founded* 2020 San Diego, United States **$150M** last round Jul 2025 - 34 [**Pathway Power** Pathway Power is a utility-scale solar and battery storage developer building a renewable energy value chain.](https://millionrounds.com/company/pathway-power) Pathway Power is a utility-scale solar and battery storage developer building a renewable energy value chain. *Founded* 2022 San Diego, United States **$150M** last round Jun 2026 - 35 [**Sidewinder Therapeutics** Sidewinder Therapeutics is a biotechnology company that offers life-saving therapies for cancer and rare diseases.](https://millionrounds.com/company/sidewinder-therapeutics) Sidewinder Therapeutics is a biotechnology company that offers life-saving therapies for cancer and rare diseases. *Founded* 2023 San Diego, United States **$137M** last round Apr 2026 - 36 [**Tealium** Tealium is a provider of customer data orchestration tools aimed to address challenges in online search, marketing, and segment targeting.](https://millionrounds.com/company/tealium) Tealium is a provider of customer data orchestration tools aimed to address challenges in online search, marketing, and segment targeting. *Founded* 2008 San Diego, United States **$133M** last round May 2019 - 37 [**Endeavor BioMedicines** Endeavor BioMedicines is a clinical-stage biotechnology company based in San Diego, California, founded in 2019.](https://millionrounds.com/company/endeavor-biomedicines) Endeavor BioMedicines is a clinical-stage biotechnology company based in San Diego, California, founded in 2019. *Founded* 2018 San Diego, United States **$133M** last round Apr 2024 - 38 [**Aptera** Aptera Motors is an electric vehicle manufacturer that designs and develops aerodynamic electric vehicles.](https://millionrounds.com/company/aptera) Aptera Motors is an electric vehicle manufacturer that designs and develops aerodynamic electric vehicles. *Founded* 2006 San Diego, United States **$131M** last round Oct 2025 - 39 [**Protego Biopharma** Protego Biopharma is a California-based biotechnology company that researches and develops small-molecule therapeutics for the treatment of protein misfolding diseases.](https://millionrounds.com/company/protego-biopharma) Protego Biopharma is a California-based biotechnology company that researches and develops small-molecule therapeutics for the treatment of protein misfolding diseases. *Founded* 2018 San Diego, United States **$130M** last round Dec 2025 - 40 [**Netradyne** Netradyne is a technology company based in San Diego, California, specializing in artificial intelligence, computer vision, and edge computing to enhance fleet](https://millionrounds.com/company/netradyne) Netradyne is a technology company based in San Diego, California, specializing in artificial intelligence, computer vision, and edge computing to enhance fleet *Founded* 2015 San Diego, United States **$127M** last round Jan 2025 - 41 [**Platform Science** Platform Science is a technology company based in San Diego, founded in 2015.](https://millionrounds.com/company/platform-science) Platform Science is a technology company based in San Diego, founded in 2015. *Founded* 2015 San Diego, United States **$125M** last round Apr 2024 - 42 [**Measurabl** Measurabl develops an ESG data management platform for commercial real estate.](https://millionrounds.com/company/measurabl) Measurabl develops an ESG data management platform for commercial real estate. *Founded* 2013 San Diego, United States **$122M** last round May 2023 - 43 [**Aspen Neuroscience** Aspen Neuroscience is a biotechnology company that specializes in personalized cell therapies.](https://millionrounds.com/company/aspen-neuroscience) Aspen Neuroscience is a biotechnology company that specializes in personalized cell therapies. *Founded* 2018 San Diego, United States **$122M** last round Nov 2025 - 44 [**Escient Pharmaceuticals** Escient Pharmaceuticals is a privately-held biotechnology company focusing on the advancement of G Protein-Coupled Receptor targeted drugs.](https://millionrounds.com/company/escient-pharmaceuticals) Escient Pharmaceuticals is a privately-held biotechnology company focusing on the advancement of G Protein-Coupled Receptor targeted drugs. *Founded* 2018 San Diego, United States **$120M** last round Nov 2022 - 45 [**Elcelyx Therapeutics** Elcelyx Therapeutics is developing nutrient sensing-based products for weight management and obesity-related metabolic disorders.](https://millionrounds.com/company/elcelyx-therapeutics) Elcelyx Therapeutics is developing nutrient sensing-based products for weight management and obesity-related metabolic disorders. *Founded* 2010 San Diego, United States **$117M** last round Oct 2015 - 46 [**Biolinq** Biolinq is a private healthcare technology company based in San Diego, California, founded in 2012.](https://millionrounds.com/company/biolinq) Biolinq is a private healthcare technology company based in San Diego, California, founded in 2012. *Founded* 2012 San Diego, United States **$115M** last round Mar 2025 - 47 [**Brain Corp** Brain Corp is a San Diego-based company founded in 2009, specializing in autonomous technology and robotic AI software.](https://millionrounds.com/company/brain-corp) Brain Corp is a San Diego-based company founded in 2009, specializing in autonomous technology and robotic AI software. *Founded* 2009 San Diego, United States **$114M** last round Jul 2016 - 48 [**Accumetrics** Accumetrics develops, manufactures, and markets the VerifyNow System, a suite of assays for the assessment of platelet function](https://millionrounds.com/company/accumetrics) Accumetrics develops, manufactures, and markets the VerifyNow System, a suite of assays for the assessment of platelet function *Founded* 1996 San Diego, United States **$111M** last round Aug 2013 - 49 [**RayThera** RayThera is dedicated to developing small molecule therapies specifically targeting unmet needs in immunology.](https://millionrounds.com/company/raythera) RayThera is dedicated to developing small molecule therapies specifically targeting unmet needs in immunology. *Founded* - San Diego, United States **$110M** last round Apr 2025 - 50 [**Human Longevity** Human Longevity is a genomic-based, health intelligence company empowering proactive healthcare and enabling a life better lived.](https://millionrounds.com/company/human-longevity) Human Longevity is a genomic-based, health intelligence company empowering proactive healthcare and enabling a life better lived. *Founded* 2013 San Diego, United States **$110M** last round Aug 2024 **Total funding** how the list is ranked **15 November 2026** updated nightly **Rounds we track** source: Millionrounds Every startup we hold in San Diego, ranked by the total it has raised in rounds we hold. Nobody pays to be on a list. ## Who backed them? Open any company for its rounds and investors, or search the investors who back startups in San Diego in the app, with filters, lists and exports. [Find their investors](https://millionrounds.com/login?join=1&next=/app/investors)[All top lists](https://millionrounds.com/top-lists) ## More startup lists [See all](https://millionrounds.com/top-lists?t=All%20startups) [*O* *A* *X* **Startups in the United States** 42,176 companies · $870B](https://millionrounds.com/top-lists/startups-united-states)[*SC* *N* *F* **Startups in the United Kingdom** 8,355 companies · $79B](https://millionrounds.com/top-lists/startups-united-kingdom)[*O* *D* *TM* **Startups in San Francisco** 4,251 companies · $350B](https://millionrounds.com/top-lists/startups-san-francisco)[*W* *K* *P* **Startups in New York** 3,729 companies · $67B](https://millionrounds.com/top-lists/startups-new-york)[*F* *IL* *PD* **Startups in London** 3,521 companies · $51B](https://millionrounds.com/top-lists/startups-london)[*MA* *M* *TE* **Startups in France** 3,025 companies · $32B](https://millionrounds.com/top-lists/startups-france)[*C* *H8* *AP* **Startups in Canada** 2,950 companies · $38B](https://millionrounds.com/top-lists/startups-canada)[*B* *D* *AF* **Startups in China** 2,168 companies · $163B](https://millionrounds.com/top-lists/startups-china) ## More lists for San Diego [See all](https://millionrounds.com/top-lists?r=San%20Diego) [*CT* *AB* *E* **Biotech startups in San Diego** 154 companies · $9.3B](https://millionrounds.com/top-lists/biotech-startups-san-diego)[*AB* *E* *VT* **Healthcare startups in San Diego** 81 companies · $6.5B](https://millionrounds.com/top-lists/healthcare-startups-san-diego)[*A* *T* *IA* **IT Services startups in San Diego** 39 companies · $396M](https://millionrounds.com/top-lists/it-services-startups-san-diego)[*SA* *N* *BC* **AI startups in San Diego** 31 companies · $7.6B](https://millionrounds.com/top-lists/ai-startups-san-diego)[*PT* *ST* *PB* **Pharma startups in San Diego** 22 companies · $904M](https://millionrounds.com/top-lists/pharma-startups-san-diego)[*M* *C* *C* **Big Data & Analytics startups in San Diego** 19 companies · $381M](https://millionrounds.com/top-lists/big-data-startups-san-diego)[*L* *T* *W* **Software startups in San Diego** 14 companies · $811M](https://millionrounds.com/top-lists/software-startups-san-diego)[*AP* *P* *G* **Internet startups in San Diego** 10 companies · $126M](https://millionrounds.com/top-lists/internet-startups-san-diego)