# Top 50 Startups in Irvine by Funding (2026)

> The 50 best-funded startups in Irvine, ranked by total funding raised: $16B combined. With founding year, headquarters and each company's rounds.

Source: https://millionrounds.com/top-lists/startups-irvine (Millionrounds; every figure on the page links to its filing or article)

- 1 [**Rivian** Rivian is an automotive technology company that develops products and services to advance the shift to sustainable mobility.](https://millionrounds.com/company/rivian) Rivian is an automotive technology company that develops products and services to advance the shift to sustainable mobility. *Founded* 2009 Irvine, United States **$9.2B** last round Jul 2025
- 2 [**American Healthcare REIT** American Healthcare REIT provides and offers financial support and assistance on buildings.](https://millionrounds.com/company/american-healthcare-reit) American Healthcare REIT provides and offers financial support and assistance on buildings. *Founded* 2011 Irvine, United States **$1.2B** last round May 2026
- 3 [**FieldAI** FieldAI is the general-purpose brain making robots autonomous in complex, risky, real-world environments.](https://millionrounds.com/company/fieldai) FieldAI is the general-purpose brain making robots autonomous in complex, risky, real-world environments. *Founded* - Irvine, United States **$1.1B** last round Oct 2026
- 4 [**Acorns** Acorns is a global financial wellness app that focuses on micro-investing, helping everyday people and families save and invest small amounts of money for long-](https://millionrounds.com/company/acorns) Acorns is a global financial wellness app that focuses on micro-investing, helping everyday people and families save and invest small amounts of money for long- *Founded* 2012 Irvine, United States **$438M** last round Mar 2022
- 5 [**Celero Communications** Celero Communications is a semiconductor company founded in 2024, based in Irvine, California, with design centers in Canada and Argentina.](https://millionrounds.com/company/celero-communications) Celero Communications is a semiconductor company founded in 2024, based in Irvine, California, with design centers in Canada and Argentina. *Founded* 2024 Irvine, United States **$375M** last round Sept 2026
- 6 [**Beta Bionics** Beta Bionics is a biotechnology company that develops an integrated bionic pancreas system called the iLet.](https://millionrounds.com/company/beta-bionics) Beta Bionics is a biotechnology company that develops an integrated bionic pancreas system called the iLet. *Founded* 2015 Irvine, United States **$296M** last round Sept 2026
- 7 [**Solarflare Communications** Solarflare Communications is a technology company based in Irvine, California, founded in 2001.](https://millionrounds.com/company/solarflare-communications) Solarflare Communications is a technology company based in Irvine, California, founded in 2001. *Founded* 2001 Irvine, United States **$243M** last round Jan 2015
- 8 [**CG Oncology** CG Oncology is a clinical-stage biopharmaceutical company focused on the development of oncolytic immunotherapies to combat cancer.](https://millionrounds.com/company/cg-oncology) CG Oncology is a clinical-stage biopharmaceutical company focused on the development of oncolytic immunotherapies to combat cancer. *Founded* 2010 Irvine, United States **$238M** last round Dec 2024
- 9 [**Menlo Micro** Menlo Micro is a semiconductor technology company based in Irvine, California, founded in December 2016 as a spin-out from General Electric.](https://millionrounds.com/company/menlo-micro) Menlo Micro is a semiconductor technology company based in Irvine, California, founded in December 2016 as a spin-out from General Electric. *Founded* 2016 Irvine, United States **$213M** last round Mar 2022
- 10 [**Restaurant365** Restaurant365 is an enterprise management software for restaurants that provides accounting, inventory, scheduling, and payroll solutions.](https://millionrounds.com/company/restaurant365) Restaurant365 is an enterprise management software for restaurants that provides accounting, inventory, scheduling, and payroll solutions. *Founded* 2011 Irvine, United States **$195M** last round May 2024
- 11 [**Evolus** Evolus medical aesthetics focused on providing physicians and their patients with expanded choices in aesthetic procedures and treatments.](https://millionrounds.com/company/evolus) Evolus medical aesthetics focused on providing physicians and their patients with expanded choices in aesthetic procedures and treatments. *Founded* 2012 Irvine, United States **$150M** last round May 2025
- 12 [**Axonics Modulation Technologies** Axonics Modulation Technologies is a pre-revenue company developing novel implantable neuromodulation.](https://millionrounds.com/company/axonics-modulation-technologies) Axonics Modulation Technologies is a pre-revenue company developing novel implantable neuromodulation. *Founded* 2012 Irvine, United States **$144M** last round Aug 2022
- 13 [**Auction.com** Auction.com is the largest online marketplace for foreclosure and bank-owned real estate auctions in the United States.](https://millionrounds.com/company/auction-com) Auction.com is the largest online marketplace for foreclosure and bank-owned real estate auctions in the United States. *Founded* 2007 Irvine, United States **$142M** last round Mar 2014
- 14 [**Cloudbreak Therapeutics** Cloudbreak Therapeutics is a clinical stage biotechnology company](https://millionrounds.com/company/cloudbreak-therapeutics) Cloudbreak Therapeutics is a clinical stage biotechnology company *Founded* 2015 Irvine, United States **$130M** last round Jan 2022
- 15 [**Ambros Therapeutics** Ambros Therapeutics is a clinical-stage biotechnology company.](https://millionrounds.com/company/ambros-therapeutics) Ambros Therapeutics is a clinical-stage biotechnology company. *Founded* - Irvine, United States **$125M** last round Dec 2025
- 16 [**Tarsus Pharmaceuticals** Tarsus Pharmaceuticals is a clinical-stage biopharmaceutical company that develops treatments for diseases with high unmet need.](https://millionrounds.com/company/tarsus-pharmaceuticals) Tarsus Pharmaceuticals is a clinical-stage biopharmaceutical company that develops treatments for diseases with high unmet need. *Founded* 2017 Irvine, United States **$125M** last round Mar 2025
- 17 [**Turion Space** Turion Space is an aerospace and defense company based in Irvine, California, founded in 2021 by a team from SpaceX.](https://millionrounds.com/company/turion-space) Turion Space is an aerospace and defense company based in Irvine, California, founded in 2021 by a team from SpaceX. *Founded* 2021 Irvine, United States **$115M** last round Apr 2026
- 18 [**Spot Runner** Spot Runner, Inc - The world's first TV advertising platform for local advertisers.](https://millionrounds.com/company/spot-runner) Spot Runner, Inc - The world's first TV advertising platform for local advertisers. *Founded* 2003 Irvine, United States **$101M** last round May 2008
- 19 [**Hyperice** Our mission is simple - to help everyone on Earth move better, live better and be better.](https://millionrounds.com/company/hyperice) Our mission is simple - to help everyone on Earth move better, live better and be better. *Founded* 2011 Irvine, United States **$100M** last round Jul 2023
- 20 [**WiSpry** WiSpry, a fabless semiconductor company, develops RF silicon integrated circuits and components for wireless communication products.](https://millionrounds.com/company/wispry) WiSpry, a fabless semiconductor company, develops RF silicon integrated circuits and components for wireless communication products. *Founded* 2002 Irvine, United States **$71M** last round Jul 2014
- 21 [**Terran Orbital** Terran Orbital is a leading manufacturer of small satellites primarily serving the United States and Allied aerospace and defense industries.](https://millionrounds.com/company/terran-orbital) Terran Orbital is a leading manufacturer of small satellites primarily serving the United States and Allied aerospace and defense industries. *Founded* 2013 Irvine, United States **$69M** last round Sept 2023
- 22 [**BlueCava** BlueCava is a fast growing provider of cross screen reach, targeting and measurement products for brands, advertisers, data companies and adtech players.](https://millionrounds.com/company/bluecava) BlueCava is a fast growing provider of cross screen reach, targeting and measurement products for brands, advertisers, data companies and adtech players. *Founded* 2010 Irvine, United States **$65M** last round Sept 2015
- 23 [**Neomend** Neomend is a biomedical device company engaged in the development and commercialization of surgical wound healing products.](https://millionrounds.com/company/neomend) Neomend is a biomedical device company engaged in the development and commercialization of surgical wound healing products. *Founded* 1999 Irvine, United States **$62M** last round Aug 2011
- 24 [**Greenwave Systems** Greenwave Systems is a software and services company that leverages Internet of Things technologies to help clients deploy managed services.](https://millionrounds.com/company/greenwave-systems) Greenwave Systems is a software and services company that leverages Internet of Things technologies to help clients deploy managed services. *Founded* 2008 Irvine, United States **$60M** last round May 2016
- 25 [**Casa Azul Spirits** Casa Azul Spirits specializes in the production of alcoholic beverages, particularly tequila.](https://millionrounds.com/company/casa-azul-spirits) Casa Azul Spirits specializes in the production of alcoholic beverages, particularly tequila. *Founded* 2021 Irvine, United States **$58M** last round Aug 2021
- 26 [**Silverado** Silverado Senior Living, based in Irvine, California, specializes in memory care and assisted living for individuals with memory impairments, such as Alzheimer’](https://millionrounds.com/company/silverado) Silverado Senior Living, based in Irvine, California, specializes in memory care and assisted living for individuals with memory impairments, such as Alzheimer’ *Founded* 1996 Irvine, United States **$51M** last round Jun 2018
- 27 [**Drybar** Drybar is a retail chain exclusively for blow-drying hair for a reduced price compared to traditional salons.](https://millionrounds.com/company/drybar) Drybar is a retail chain exclusively for blow-drying hair for a reduced price compared to traditional salons. *Founded* 2009 Irvine, United States **$51M** last round Jun 2014
- 28 [**In-Charge Energy** In-Charge Energy is an energy solutions company that is accelerating electrification of the transportation industry.](https://millionrounds.com/company/in-charge-energy) In-Charge Energy is an energy solutions company that is accelerating electrification of the transportation industry. *Founded* - Irvine, United States **$46M** last round Jun 2026
- 29 [**Vascular Dynamics** Vascular Dynamics is a medical device company founded in 2008 and headquartered in Irvine, California.](https://millionrounds.com/company/vascular-dynamics) Vascular Dynamics is a medical device company founded in 2008 and headquartered in Irvine, California. *Founded* 2008 Irvine, United States **$46M** last round Mar 2017
- 30 [**Uplogix** Uplogix provides network monitoring and management solutions that improve control, connectivity and security.](https://millionrounds.com/company/uplogix) Uplogix provides network monitoring and management solutions that improve control, connectivity and security. *Founded* 2003 Irvine, United States **$45M** last round Feb 2014
- 31 [**INBRACE** Swift Health Systems is a stealth stage start-up medical device company, developing INBRACE.](https://millionrounds.com/company/inbrace) Swift Health Systems is a stealth stage start-up medical device company, developing INBRACE. *Founded* 2014 Irvine, United States **$45M** last round Jul 2022
- 32 [**Local.com** Local.com owns and operates a leading local search site and network in the United States.](https://millionrounds.com/company/local-com) Local.com owns and operates a leading local search site and network in the United States. *Founded* 2015 Irvine, United States **$43M** last round Jan 2024
- 33 [**Irvine Sensors Corporation** Irvine Sensors Corporation is a California-based company specializing in sensor systems, particularly in advanced imaging, video analytics, and intelligent sens](https://millionrounds.com/company/irvine-sensors-corporation) Irvine Sensors Corporation is a California-based company specializing in sensor systems, particularly in advanced imaging, video analytics, and intelligent sens *Founded* 2013 Irvine, United States **$42M** last round Nov 2013
- 34 [**Red 5 Studios** Red 5 Studios was an American video game development company founded in 2005-2006 by former Blizzard Entertainment employees, including Mark E.](https://millionrounds.com/company/red-5-studios) Red 5 Studios was an American video game development company founded in 2005-2006 by former Blizzard Entertainment employees, including Mark E. *Founded* 2006 Irvine, United States **$42M** last round Mar 2010
- 35 [**Alternativ** Alternativ is a financial firm that specializes in wealth advisory with a focus on alternative assets.](https://millionrounds.com/company/alternativ) Alternativ is a financial firm that specializes in wealth advisory with a focus on alternative assets. *Founded* 2021 Irvine, United States **$41M** last round Sept 2023
- 36 [**Movandi** Movandi is a semiconductor and systems innovator focused on next-generation wireless communications, particularly in 5G millimeter-wave (mmWave) technology.](https://millionrounds.com/company/movandi) Movandi is a semiconductor and systems innovator focused on next-generation wireless communications, particularly in 5G millimeter-wave (mmWave) technology. *Founded* 2016 Irvine, United States **$40M** last round Oct 2025
- 37 [**Syntiant** Syntiant is a deep learning tech company providing AI voice and sensor solutions.](https://millionrounds.com/company/syntiant) Syntiant is a deep learning tech company providing AI voice and sensor solutions. *Founded* 2017 Irvine, United States **$40M** last round Mar 2026
- 38 [**Fugoo** Fugoo has a long history in strategic product design of hardware and software.](https://millionrounds.com/company/fugoo) Fugoo has a long history in strategic product design of hardware and software. *Founded* 2009 Irvine, United States **$40M** last round Oct 2009
- 39 [**Breathe Technologies** Breathe Technologies provide healthcare providers and patients with respiratory therapies that optimize breathing and mobility.](https://millionrounds.com/company/breathe-technologies) Breathe Technologies provide healthcare providers and patients with respiratory therapies that optimize breathing and mobility. *Founded* 2005 Irvine, United States **$39M** last round Jan 2015
- 40 [**PatientFi** PatientFi is a financial technology company based in Irvine, California, that focuses on modernizing healthcare financing.](https://millionrounds.com/company/patientfi) PatientFi is a financial technology company based in Irvine, California, that focuses on modernizing healthcare financing. *Founded* 2017 Irvine, United States **$38M** last round Jun 2026
- 41 [**WebVisible** WebVisible, Inc.](https://millionrounds.com/company/webvisible) WebVisible, Inc. *Founded* 2001 Irvine, United States **$37M** last round Feb 2010
- 42 [**Agendia** Agendia is a molecular diagnostics company focused on precision oncology, specifically for early-stage breast cancer.](https://millionrounds.com/company/agendia) Agendia is a molecular diagnostics company focused on precision oncology, specifically for early-stage breast cancer. *Founded* 2003 Irvine, United States **$35M** last round Jul 2018
- 43 [**Acclarent** Acclarent is a medical device company that develops new technologies to treat patients suffering from ENT disorders.](https://millionrounds.com/company/acclarent) Acclarent is a medical device company that develops new technologies to treat patients suffering from ENT disorders. *Founded* 2004 Irvine, United States **$35M** last round Apr 2007
- 44 [**lensgen** LensGen creates adaptive intraocular lenses for the treatment of presbyopia.](https://millionrounds.com/company/lensgen) LensGen creates adaptive intraocular lenses for the treatment of presbyopia. *Founded* 2011 Irvine, United States **$34M** last round Aug 2020
- 45 [**NGD Systems** NGD Systems manufactures the world’s most advanced computational storage drives (CSDs) that allow customers to compute anywhere.](https://millionrounds.com/company/ngd-systems) NGD Systems manufactures the world’s most advanced computational storage drives (CSDs) that allow customers to compute anywhere. *Founded* 2013 Irvine, United States **$32M** last round Feb 2020
- 46 [**Numecent** Numecent develops a 'cloudpaging' technology that transmits pre-virtualized native software instructions in a transient manner.](https://millionrounds.com/company/numecent) Numecent develops a 'cloudpaging' technology that transmits pre-virtualized native software instructions in a transient manner. *Founded* 2012 Irvine, United States **$31M** last round Nov 2015
- 47 [**TAE Life Sciences** TAE Life Sciences is a biotechnology company founded in 2017 and based in Irvine, California.](https://millionrounds.com/company/tae-life-sciences) TAE Life Sciences is a biotechnology company founded in 2017 and based in Irvine, California. *Founded* 2017 Irvine, United States **$30M** last round Jun 2020
- 48 [**Seragon Pharmaceuticals** Seragon Pharmaceuticals is a research-based company dedicated to improving human and animal health through innovative science.](https://millionrounds.com/company/seragon-pharmaceuticals) Seragon Pharmaceuticals is a research-based company dedicated to improving human and animal health through innovative science. *Founded* 2013 Irvine, United States **$30M** last round Oct 2013
- 49 [**Water Health International** WaterHealth International provides de-centralized, scalable, safe, and affordable water solutions.](https://millionrounds.com/company/water-health-international) WaterHealth International provides de-centralized, scalable, safe, and affordable water solutions. *Founded* 1995 Irvine, United States **$29M** last round Sept 2014
- 50 [**SecureAuth** SecureAuth is an identity and access management company that delivers a truly passwordless continuous experience to everyone, everywhere.](https://millionrounds.com/company/secureauth) SecureAuth is an identity and access management company that delivers a truly passwordless continuous experience to everyone, everywhere. *Founded* 2005 Irvine, United States **$28M** last round Aug 2014

**Total funding** how the list is ranked

**15 November 2026** updated nightly

**Rounds we track** source: Millionrounds

Every startup we hold in Irvine, ranked by the total it has raised in rounds we hold. Nobody pays to be on a list.

## Who backed them?

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## More startup lists

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[*O* *A* *X* **Startups in the United States** 42,176 companies · $870B](https://millionrounds.com/top-lists/startups-united-states)[*SC* *N* *F* **Startups in the United Kingdom** 8,355 companies · $79B](https://millionrounds.com/top-lists/startups-united-kingdom)[*O* *D* *TM* **Startups in San Francisco** 4,251 companies · $350B](https://millionrounds.com/top-lists/startups-san-francisco)[*W* *K* *P* **Startups in New York** 3,729 companies · $67B](https://millionrounds.com/top-lists/startups-new-york)[*F* *IL* *PD* **Startups in London** 3,521 companies · $51B](https://millionrounds.com/top-lists/startups-london)[*MA* *M* *TE* **Startups in France** 3,025 companies · $32B](https://millionrounds.com/top-lists/startups-france)[*C* *H8* *AP* **Startups in Canada** 2,950 companies · $38B](https://millionrounds.com/top-lists/startups-canada)[*B* *D* *AF* **Startups in China** 2,168 companies · $163B](https://millionrounds.com/top-lists/startups-china)

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[*BB* *AM* *S* **Healthcare startups in Irvine** 25 companies · $807M](https://millionrounds.com/top-lists/healthcare-startups-irvine)[*BB* *CO* *E* **Biotech startups in Irvine** 24 companies · $1.3B](https://millionrounds.com/top-lists/biotech-startups-irvine)[*L* *ZS* *C* **IT Services startups in Irvine** 18 companies · $116M](https://millionrounds.com/top-lists/it-services-startups-irvine)[*B* *U* *N* **Software startups in Irvine** 12 companies · $205M](https://millionrounds.com/top-lists/software-startups-irvine)[*F* *CC* *S* **AI startups in Irvine** 10 companies · $1.6B](https://millionrounds.com/top-lists/ai-startups-irvine)
