# Top 50 RNA Therapeutics Startups Worldwide by Funding (2026)

> The 50 best-funded RNA therapeutics startups worldwide, ranked by total funding raised: $3.7B combined.

Source: https://millionrounds.com/top-lists/rna-therapeutics-startups (Millionrounds; every figure on the page links to its filing or article)

- 1 [**STORM Therapeutics** Targeting pathways that modify RNA to deliver novel cancer therapeutics](https://millionrounds.com/company/storm-therapeutics) Targeting pathways that modify RNA to deliver novel cancer therapeutics *Founded* 2015 Cambridge, United Kingdom **$317M** last round Apr 2026
- 2 [**ReNAgade Therapeutics** ReNAgade Therapeutics focuses on the boundless potential of RNA therapeutics to treat disease.](https://millionrounds.com/company/renagade-therapeutics) ReNAgade Therapeutics focuses on the boundless potential of RNA therapeutics to treat disease. *Founded* 2021 Cambridge, United States **$300M** last round May 2023
- 3 [**Orbital Therapeutics** Orbital Therapeutics is a biotechnology company that develops RNA-based medicines to treat disease in humans.](https://millionrounds.com/company/orbital-therapeutics) Orbital Therapeutics is a biotechnology company that develops RNA-based medicines to treat disease in humans. *Founded* 2022 New York, United States **$270M** last round Apr 2023
- 4 [**Strand Therapeutics** Strand Therapeutics is a biopharmaceutical company applying synthetic biology to RNA therapeutics to develop single dose mRNA treatments.](https://millionrounds.com/company/strand-therapeutics) Strand Therapeutics is a biopharmaceutical company applying synthetic biology to RNA therapeutics to develop single dose mRNA treatments. *Founded* 2017 Cambridge, United States **$267M** last round Mar 2026
- 5 [**Shape Therapeutics** A biotechnology company developing RNA technologies to shape the future of gene therapy](https://millionrounds.com/company/shape-therapeutics) A biotechnology company developing RNA technologies to shape the future of gene therapy *Founded* 2018 Seattle, United States **$260M** last round Jul 2026
- 6 [**Stoke Therapeutics** Stoke is developing antisense oligonucleotide medicines that target RNA splicing to increase gene expression for treatment.](https://millionrounds.com/company/stoke-therapeutics) Stoke is developing antisense oligonucleotide medicines that target RNA splicing to increase gene expression for treatment. *Founded* 2014 Bedford, United States **$255M** last round Mar 2024
- 7 [**Orna Therapeutics** Orna Therapeutics is a biotechnology company that specializes in fully engineered circular RNA therapeutics to treat various diseases.](https://millionrounds.com/company/orna-therapeutics) Orna Therapeutics is a biotechnology company that specializes in fully engineered circular RNA therapeutics to treat various diseases. *Founded* 2019 Cambridge, United States **$221M** last round Aug 2022
- 8 [**Nutcracker Therapeutics** Nutcracker Therapeutics is a biotechnology company based in Emeryville, California, specializing in mRNA therapeutics and a unique GMP manufacturing platform.](https://millionrounds.com/company/nutcracker-therapeutics) Nutcracker Therapeutics is a biotechnology company based in Emeryville, California, specializing in mRNA therapeutics and a unique GMP manufacturing platform. *Founded* 2018 Emeryville, United States **$167M** last round Mar 2022
- 9 [**AIRNA** AIRNA is a biotechnology company founded in 2021, focused on discovering and developing RNA editing therapeutics.](https://millionrounds.com/company/airna) AIRNA is a biotechnology company founded in 2021, focused on discovering and developing RNA editing therapeutics. *Founded* 2021 Cambridge, United States **$155M** last round Apr 2025
- 10 [**Skyhawk Therapeutics** Skyhawk Therapeutics is a clinical-stage biotechnology company located in Waltham, Massachusetts.](https://millionrounds.com/company/skyhawk-therapeutics) Skyhawk Therapeutics is a clinical-stage biotechnology company located in Waltham, Massachusetts. *Founded* 2016 Waltham, United States **$133M** last round Sept 2021
- 11 [**Addition Therapeutics** Addition Therapeutics develops RNA-only therapeutics using PRINT technology for genetic medicine.](https://millionrounds.com/company/addition-therapeutics) Addition Therapeutics develops RNA-only therapeutics using PRINT technology for genetic medicine. *Founded* - South San Francisco, United States **$100M** last round Dec 2025
- 12 [**DTx Pharma** DTx Pharma is a biotechnology company creating novel RNA-based therapeutics to treat the genetic drivers of disease.](https://millionrounds.com/company/dtx-pharma) DTx Pharma is a biotechnology company creating novel RNA-based therapeutics to treat the genetic drivers of disease. *Founded* 2017 San Diego **$100M** last round Mar 2021
- 13 [**Atalanta Therapeutics** Atalanta Therapeutics is a biotechnology company based in Boston, Massachusetts, focused on developing innovative therapies for central nervous system (CNS) diseases.](https://millionrounds.com/company/atalanta-therapeutics) Atalanta Therapeutics is a biotechnology company based in Boston, Massachusetts, focused on developing innovative therapies for central nervous system (CNS) diseases. *Founded* 2018 Boston, United States **$97M** last round Jan 2025
- 14 [**ProQR Therapeutics** Changing lives is what drives us at ProQR Therapeutics.](https://millionrounds.com/company/proqr-therapeutics) Changing lives is what drives us at ProQR Therapeutics. *Founded* 2012 Leiden, Netherlands **$68M** last round Jun 2026
- 15 [**Vivatides Therapeutics** Vivatides Therapeutics develops RNA treatments to help improve patients' lives using biotechnology research.](https://millionrounds.com/company/vivatides-therapeutics) Vivatides Therapeutics develops RNA treatments to help improve patients' lives using biotechnology research. *Founded* - Woburn, United States **$64M** last round May 2026
- 16 [**Redona Therapeutics** Redona Therapeutics specializes in the modulation of functional non-coding RNA to treat cancer and other human diseases.](https://millionrounds.com/company/redona-therapeutics) Redona Therapeutics specializes in the modulation of functional non-coding RNA to treat cancer and other human diseases. *Founded* 2016 Watertown, United States **$61M** last round Jul 2023
- 17 [**Switch Therapeutics** Switch Therapeutics is a preclinical-stage biotechnology company founded in 2020, focused on developing innovative RNA interference (RNAi) therapies for central](https://millionrounds.com/company/switch-therapeutics) Switch Therapeutics is a preclinical-stage biotechnology company founded in 2020, focused on developing innovative RNA interference (RNAi) therapies for central *Founded* 2020 San Francisco, United States **$52M** last round Mar 2023
- 18 [**Arnatar Therapeutics** Arnatar Therapeutics is a biotechnology company founded in 2022, based in San Diego, California, with operations in Shanghai, China.](https://millionrounds.com/company/arnatar-therapeutics) Arnatar Therapeutics is a biotechnology company founded in 2022, based in San Diego, California, with operations in Shanghai, China. *Founded* 2022 San Diego, United States **$52M** last round Apr 2024
- 19 [**Nucleonics** Nucleonics is a biotechnology company focused on RNA interference-based therapeutics.](https://millionrounds.com/company/nucleonics) Nucleonics is a biotechnology company focused on RNA interference-based therapeutics. *Founded* 2001 United States **$49M** last round Jun 2004
- 20 [**Aerska** Aerska is a biotechnology company focused on developing targeted RNA medicines to treat brain diseases.](https://millionrounds.com/company/aerska) Aerska is a biotechnology company focused on developing targeted RNA medicines to treat brain diseases. *Founded* - Dublin, Ireland **$49M** last round May 2026
- 21 [**Aptadir Therapeutics** Aptadir Therapeutics is a biotechnology startup based in Milan, focused on developing RNA inhibitor-based therapies for cancer and genetic disorders.](https://millionrounds.com/company/aptadir-therapeutics) Aptadir Therapeutics is a biotechnology startup based in Milan, focused on developing RNA inhibitor-based therapies for cancer and genetic disorders. *Founded* - Milano, United Kingdom **$47M** last round Sept 2026
- 22 [**NextRNA Therapeutics** NextRNA Therapeutics is a biotechnology company based in Boston, Massachusetts, focused on developing innovative therapies that target long non-coding RNAs (lncRNAs).](https://millionrounds.com/company/nextrna-therapeutics) NextRNA Therapeutics is a biotechnology company based in Boston, Massachusetts, focused on developing innovative therapies that target long non-coding RNAs (lncRNAs). *Founded* 2020 Boston, United States **$47M** last round Mar 2022
- 23 [**Starna Therapeutics** Starna Therapeutics is a biotechnology company based in Suzhou, China, founded in August 2021.](https://millionrounds.com/company/starna-therapeutics) Starna Therapeutics is a biotechnology company based in Suzhou, China, founded in August 2021. *Founded* 2021 Suzhou, China **$42M** last round Oct 2025
- 24 [**Argo Biopharma** Argo Biopharma is a clinical-stage biotechnology company based in Shanghai, China, founded in 2021.](https://millionrounds.com/company/argo-biopharma) Argo Biopharma is a clinical-stage biotechnology company based in Shanghai, China, founded in 2021. *Founded* 2021 Shanghai, China **$41M** last round Nov 2023
- 25 [**ARTHEx Biotech** ARTHEx Biotech is a clinical-stage biotechnology company based in Paterna, Valencia, Spain.](https://millionrounds.com/company/arthex-biotech) ARTHEx Biotech is a clinical-stage biotechnology company based in Paterna, Valencia, Spain. *Founded* 2019 Paterna, Spain **$41M** last round Sept 2025
- 26 [**SRTD Biotech** SRTD Biotech GmbH is a biotechnology company based in Jülich, Germany, specializing in the development of RNA-based therapeutics.](https://millionrounds.com/company/srtd-biotech) SRTD Biotech GmbH is a biotechnology company based in Jülich, Germany, specializing in the development of RNA-based therapeutics. *Founded* - Juelich, Germany **$35M** last round Nov 2026
- 27 [**Avidity** Avidity is a RNA therapeutics software solutions provider company.](https://millionrounds.com/company/avidity) Avidity is a RNA therapeutics software solutions provider company. *Founded* 1996 Aurora, United States **$32M** last round Oct 2018
- 28 [**Ractigen Therapeutics** Ractigen Therapeutics is a clinical-stage biopharmaceutical company based in Suzhou, Jiangsu, China, founded in 2016.](https://millionrounds.com/company/ractigen-therapeutics) Ractigen Therapeutics is a clinical-stage biopharmaceutical company based in Suzhou, Jiangsu, China, founded in 2016. *Founded* 2017 Suzhou, China **$30M** last round Jan 2022
- 29 [**CAMP4 Therapeutics** CAMP4 Therapeutics is a biotechnology company that uses RNA to restore healthy gene expression.](https://millionrounds.com/company/camp4-therapeutics) CAMP4 Therapeutics is a biotechnology company that uses RNA to restore healthy gene expression. *Founded* 2016 Cambridge, United States **$30M** last round Dec 2025
- 30 [**OncXerna Therapeutics** OncXerna Therapeutics offers precision medicine using an innovative RNA-based biomarker platform.](https://millionrounds.com/company/oncxerna-therapeutics) OncXerna Therapeutics offers precision medicine using an innovative RNA-based biomarker platform. *Founded* 2018 Waltham, United States **$30M** last round Mar 2022
- 31 [**Envisagenics** Envisagenics is an AI-driven biotechnology company founded in 2014, focusing on the discovery and development of novel RNA splicing therapeutics for oncology an](https://millionrounds.com/company/envisagenics) Envisagenics is an AI-driven biotechnology company founded in 2014, focusing on the discovery and development of novel RNA splicing therapeutics for oncology an *Founded* 2014 New York, United States **$27M** last round Jun 2024
- 32 [**Transcode Therapeutics** TransCode Therapeutics is an RNA oncology company that develops and commercializes drugs for the treatment of metastatic cancer.](https://millionrounds.com/company/transcode-therapeutics) TransCode Therapeutics is an RNA oncology company that develops and commercializes drugs for the treatment of metastatic cancer. *Founded* 2016 Newton, United States **$26M** last round Apr 2026
- 33 [**Rona Therapeutics** Rona Therapeutics is a biotechnology company based in Shanghai, China, founded in 2021.](https://millionrounds.com/company/rona-therapeutics) Rona Therapeutics is a biotechnology company based in Shanghai, China, founded in 2021. *Founded* 2021 Shanghai, China **$25M** last round Mar 2025
- 34 [**Eleven Therapeutics** Eleven Therapeutics is a biotechnology company founded in 2020, specializing in next-generation RNA therapeutics.](https://millionrounds.com/company/eleven-therapeutics) Eleven Therapeutics is a biotechnology company founded in 2020, specializing in next-generation RNA therapeutics. *Founded* 2020 Cambridge, United Kingdom **$22M** last round Aug 2022
- 35 [**Tacit Therapeutics** Tacit Therapeutics created RNA-targeting treatments for devastating diseases.](https://millionrounds.com/company/tacit-therapeutics) Tacit Therapeutics created RNA-targeting treatments for devastating diseases. *Founded* 2021 South San Francisco, United States **$19M** last round Mar 2026
- 36 [**Innovac Therapeutics** Innovac Therapeutics is a biotechnology company based in Cambridge, Massachusetts, founded in 2022.](https://millionrounds.com/company/innovac-therapeutics) Innovac Therapeutics is a biotechnology company based in Cambridge, Massachusetts, founded in 2022. *Founded* - Cambridge, United States **$18M** last round Sept 2023
- 37 [**Oligon** Oligon Therapeutics Inc.](https://millionrounds.com/company/oligon) Oligon Therapeutics Inc. *Founded* - Montreal, United States **$14M** last round Sept 2025
- 38 [**Stemirna** Stemirna Therapeutics is a RNA technology based drug development company designed to maximize the potential of RNA science.](https://millionrounds.com/company/stemirna) Stemirna Therapeutics is a RNA technology based drug development company designed to maximize the potential of RNA science. *Founded* - China **$14M** last round May 2023
- 39 [**Vico Therapeutics** Vico Therapeutics is a clinical-stage genetic medicines company based in Leiden, the Netherlands.](https://millionrounds.com/company/vico-therapeutics) Vico Therapeutics is a clinical-stage genetic medicines company based in Leiden, the Netherlands. *Founded* 2019 Leiden, Netherlands **$12M** last round Jun 2024
- 40 [**Therna Biosciences** Therna Biosciences is a biotechnology company based in San Francisco, founded in 2023.](https://millionrounds.com/company/therna-biosciences) Therna Biosciences is a biotechnology company based in San Francisco, founded in 2023. *Founded* 2025 San Francisco, United States **$10M** last round Aug 2025
- 41 [**Amaroq Therapeutics** Amaroq Therapeutics is a biotechnology company based in New Zealand that focuses on developing innovative cancer therapeutics targeting long non-coding RNAs (lncRNAs).](https://millionrounds.com/company/amaroq-therapeutics) Amaroq Therapeutics is a biotechnology company based in New Zealand that focuses on developing innovative cancer therapeutics targeting long non-coding RNAs (lncRNAs). *Founded* 2021 Auckland, New Zealand **$9.7M** last round Jul 2021
- 42 [**Terrain Bio** Terrain BioSciences accelerates RNA-based therapeutics and vaccine development using AI and proprietary platforms.](https://millionrounds.com/company/terrain-bio) Terrain BioSciences accelerates RNA-based therapeutics and vaccine development using AI and proprietary platforms. *Founded* - Cambridge, United States **$9.0M** last round Feb 2025
- 43 [**Heqet Therapeutics** Heqet Therapeutics is a pre-clinical stage biotechnology company based in Turin, Italy.](https://millionrounds.com/company/heqet-therapeutics) Heqet Therapeutics is a pre-clinical stage biotechnology company based in Turin, Italy. *Founded* - Deerfield, United Kingdom **$8.8M** last round Mar 2022
- 44 [**Expansion Therapeutics** Expansion Therapeutics is a biotechnology company based in Boston, focused on developing oral medicines for severe RNA-mediated diseases, particularly neurodege](https://millionrounds.com/company/expansion-therapeutics) Expansion Therapeutics is a biotechnology company based in Boston, focused on developing oral medicines for severe RNA-mediated diseases, particularly neurodege *Founded* 2016 Jupiter, United States **$6.9M** last round Jan 2023
- 45 [**Crucible Therapeutics** Crucible Therapeutics is a biotechnology company based in Sheffield, England, founded in 2023.](https://millionrounds.com/company/crucible-therapeutics) Crucible Therapeutics is a biotechnology company based in Sheffield, England, founded in 2023. *Founded* 2023 United Kingdom **$6.3M** last round Mar 2025
- 46 [**pHion Therapeutics** pHion Therapeutics is a biopharmaceutical company based in Belfast, Northern Ireland, focused on developing therapeutic and prophylactic mRNA vaccines.](https://millionrounds.com/company/phion-therapeutics) pHion Therapeutics is a biopharmaceutical company based in Belfast, Northern Ireland, focused on developing therapeutic and prophylactic mRNA vaccines. *Founded* 2017 Belfast, United Kingdom **$6.2M** last round Jun 2023
- 47 [**HDT Bio** HDT Bio is a developer of RNA vaccines and therapeutics based on LION formulation technology.](https://millionrounds.com/company/hdt-bio) HDT Bio is a developer of RNA vaccines and therapeutics based on LION formulation technology. *Founded* 2018 Seattle, United States **$6.2M** last round Sept 2026
- 48 [**XFOREST Therapeutics** XFOREST Therapeutics is a biotech company focused on drug discovery using RNA structures.](https://millionrounds.com/company/xforest-therapeutics) XFOREST Therapeutics is a biotech company focused on drug discovery using RNA structures. *Founded* - Kyoto, Japan **$6.1M** last round Jan 2025
- 49 [**CamGene Therapeutics** CamGene Therapeutics is a biotechnology company based in Cambridge, UK, focused on developing RNA-based gene medicines specifically for hearing loss.](https://millionrounds.com/company/camgene-therapeutics) CamGene Therapeutics is a biotechnology company based in Cambridge, UK, focused on developing RNA-based gene medicines specifically for hearing loss. *Founded* 2024 Cambridge, United Kingdom **$5.4M** last round May 2026
- 50 [**ReviR Therapeutics** ReviR Therapeutics is a genomics-based platform that develops novel medicines targeting human RNAs.](https://millionrounds.com/company/revir-therapeutics) ReviR Therapeutics is a genomics-based platform that develops novel medicines targeting human RNAs. *Founded* 2021 Brisbane, United States **$4.6M** last round Apr 2026

**Total funding** how the list is ranked

**15 November 2026** updated nightly

**Rounds we track** source: Millionrounds

Companies whose own description names this theme, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.

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