# Top 50 Pharma Startups in the United States by Funding (2026) > The 50 best-funded pharma startups in the United States, ranked by total funding raised: $23B combined. Source: https://millionrounds.com/top-lists/pharma-startups-united-states (Millionrounds; every figure on the page links to its filing or article) - 1 [**Altos Labs** Altos Labs focuses on cellular rejuvenation programming to restore cell health and resilience, to reverse disease to transform medicine.](https://millionrounds.com/company/altos-labs) Altos Labs focuses on cellular rejuvenation programming to restore cell health and resilience, to reverse disease to transform medicine. *Founded* 2021 San Francisco, United States **$3.0B** last round Sept 2021 - 2 [**National Resilience**](https://millionrounds.com/company/national-resilience) *Founded* 2020 United States **$1.6B** last round Jul 2026 - 3 [**Retro Biosciences** Retro Biosciences is a biotechnology company based in Redwood City, California, founded in May 2021.](https://millionrounds.com/company/retro-biosciences) Retro Biosciences is a biotechnology company based in Redwood City, California, founded in May 2021. *Founded* 2021 Redwood City, United States **$1.2B** last round May 2026 - 4 [**Resilience** Resilience is a cyber risk company based in San Francisco, founded in 2016 by experts from military intelligence, insurance, and technology.](https://millionrounds.com/company/resilience) Resilience is a cyber risk company based in San Francisco, founded in 2016 by experts from military intelligence, insurance, and technology. *Founded* 2016 New York, United States **$860M** last round Oct 2025 - 5 [**Mineralys Therapeutics** Mineralys Therapeutics is a clinical-stage biopharmaceutical company committed to developing therapy for the treatment of hypertension.](https://millionrounds.com/company/mineralys-therapeutics) Mineralys Therapeutics is a clinical-stage biopharmaceutical company committed to developing therapy for the treatment of hypertension. *Founded* 2019 Radnor, United States **$788M** last round Jun 2026 - 6 [**Dianthus Therapeutics** Dianthus Therapeutics is a biotech company developing new treatments for serious autoimmune diseases using a more targeted approach.](https://millionrounds.com/company/dianthus-therapeutics) Dianthus Therapeutics is a biotech company developing new treatments for serious autoimmune diseases using a more targeted approach. *Founded* 2019 Waltham, United States **$719M** last round Mar 2026 - 7 [**Vaxcyte** Vaxcyte focuses on developing vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide.](https://millionrounds.com/company/vaxcyte) Vaxcyte focuses on developing vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide. *Founded* 2013 San Carlos, United States **$633M** last round Jan 2026 - 8 [**Axsome Therapeutics** Axsome Therapeutics is a biopharmaceutical company that develops therapies for the management and treatment of neurological disorders.](https://millionrounds.com/company/axsome-therapeutics) Axsome Therapeutics is a biopharmaceutical company that develops therapies for the management and treatment of neurological disorders. *Founded* 2012 New York, United States **$577M** last round May 2025 - 9 [**CRISPR THERAPEUTICS** CRISPR Therapeutics is focused on the development of transformative medicines using its proprietary CRISPR/Cas9 gene-editing platform.](https://millionrounds.com/company/crispr-therapeutics) CRISPR Therapeutics is focused on the development of transformative medicines using its proprietary CRISPR/Cas9 gene-editing platform. *Founded* 2014 United States **$550M** last round Mar 2026 - 10 [**Immunovant** Immunovant is a clinical-stage biopharmaceutical company focused on enabling normal lives for patients with autoimmune diseases.](https://millionrounds.com/company/immunovant) Immunovant is a clinical-stage biopharmaceutical company focused on enabling normal lives for patients with autoimmune diseases. *Founded* 2018 New York, United States **$550M** last round Dec 2025 - 11 [**Korsana Biosciences** Korsana Biosciences develops THETA-enabled antibody therapies for neurodegenerative diseases including Alzheimer’s.](https://millionrounds.com/company/korsana-biosciences) Korsana Biosciences develops THETA-enabled antibody therapies for neurodegenerative diseases including Alzheimer’s. *Founded* - Waltham, United States **$530M** last round Sept 2026 - 12 [**MapLight Therapeutics** MapLight Therapeutics is a biopharma company that offers a platform designed to discover and develop therapeutics for brain disorders.](https://millionrounds.com/company/maplight-therapeutics) MapLight Therapeutics is a biopharma company that offers a platform designed to discover and develop therapeutics for brain disorders. *Founded* 2018 Palo Alto, United States **$523M** last round Aug 2026 - 13 [**Ollin Biosciences** Ollin Biosciences is a clinical-stage biopharmaceutical company based in Austin, Texas, founded in 2023.](https://millionrounds.com/company/ollin-biosciences) Ollin Biosciences is a clinical-stage biopharmaceutical company based in Austin, Texas, founded in 2023. *Founded* - Austin, United States **$430M** last round Jun 2026 - 14 [**Remedi SeniorCare** Remedi SeniorCare provides pharmacy services by offering automatic therapeutic interchange education and consulting and transition services.](https://millionrounds.com/company/remedi-seniorcare) Remedi SeniorCare provides pharmacy services by offering automatic therapeutic interchange education and consulting and transition services. *Founded* 1954 Baltimore, United States **$430M** last round Aug 2013 - 15 [**Arcus Biosciences** Arcus Biosciences is a biopharmaceutical company that discovers, develops, and commercializes novel therapies for the treatment of cancer.](https://millionrounds.com/company/arcus-biosciences) Arcus Biosciences is a biopharmaceutical company that discovers, develops, and commercializes novel therapies for the treatment of cancer. *Founded* 2015 Hayward, United States **$427M** last round Oct 2025 - 16 [**Zenas BioPharma** Zenas BioPharma is a biopharmaceutical company that focuses on developing immune-based therapies for patients.](https://millionrounds.com/company/zenas-biopharma) Zenas BioPharma is a biopharmaceutical company that focuses on developing immune-based therapies for patients. *Founded* 2023 Waltham, United States **$420M** last round Mar 2026 - 17 [**SpringWorks Therapeutics** SpringWorks Therapeutics is a biopharmaceutical company that develops medicines for patients with severe rare diseases and cancer.](https://millionrounds.com/company/springworks-therapeutics) SpringWorks Therapeutics is a biopharmaceutical company that develops medicines for patients with severe rare diseases and cancer. *Founded* 2017 Stamford, United States **$400M** last round Dec 2023 - 18 [**Parabilis Medicines** Parabilis Medicines is a Grupo Bugio is a biopharmaceutical firm that specializes in creating medicines.](https://millionrounds.com/company/parabilis-medicines) Parabilis Medicines is a Grupo Bugio is a biopharmaceutical firm that specializes in creating medicines. *Founded* - Cambridge, United States **$380M** last round Jun 2026 - 19 [**Madrigal Pharmaceuticals** Madrigal Pharmaceuticals is a biopharmaceutical company developing therapeutics for the treatment of cardiovascular-metabolic diseases.](https://millionrounds.com/company/madrigal-pharmaceuticals) Madrigal Pharmaceuticals is a biopharmaceutical company developing therapeutics for the treatment of cardiovascular-metabolic diseases. *Founded* 2011 Conshohocken, United States **$350M** last round Jul 2025 - 20 [**89Bio** 89bio is a biopharmaceutical company that develops clinical-stage therapies for liver and cardiometabolic diseases.](https://millionrounds.com/company/89bio) 89bio is a biopharmaceutical company that develops clinical-stage therapies for liver and cardiometabolic diseases. *Founded* 2018 San Francisco, United States **$348M** last round Jan 2025 - 21 [**Crystalys Therapeutics**](https://millionrounds.com/company/crystalys-therapeutics) *Founded* - United States **$335M** last round Jul 2026 - 22 [**NGM Biopharmaceuticals** NGM Biopharmaceuticals Inc.](https://millionrounds.com/company/ngm-biopharmaceuticals) NGM Biopharmaceuticals Inc. *Founded* 2008 South San Francisco, United States **$333M** last round Mar 2015 - 23 [**eGenesis**](https://millionrounds.com/company/egenesis) *Founded* - United States **$329M** last round Sept 2024 - 24 [**Corvus Pharmaceuticals** Corvus Pharmaceuticals is a clinical-stage biopharmaceutical company.](https://millionrounds.com/company/corvus-pharmaceuticals) Corvus Pharmaceuticals is a clinical-stage biopharmaceutical company. *Founded* 2014 Burlingame, United States **$310M** last round Jan 2026 - 25 [**Maze Therapeutics** Maze Therapeutics is an operator of a biotechnology firm used to focus on translating genetic insights into new medicines.](https://millionrounds.com/company/maze-therapeutics) Maze Therapeutics is an operator of a biotechnology firm used to focus on translating genetic insights into new medicines. *Founded* 2018 South San Francisco, United States **$300M** last round Apr 2026 - 26 [**Beeline Medicines** Beeline Medicines is a clinical-stage biotechnology company based in Boston, Massachusetts, focused on developing precision therapies for autoimmune and inflamm](https://millionrounds.com/company/beeline-medicines) Beeline Medicines is a clinical-stage biotechnology company based in Boston, Massachusetts, focused on developing precision therapies for autoimmune and inflamm *Founded* 2025 Stamford, United States **$300M** last round Apr 2026 - 27 [**ACELYRIN** ACELYRIN is a biopharma company that identifies, acquires, and accelerates the development and commercialization of life-changing therapies.](https://millionrounds.com/company/acelyrin) ACELYRIN is a biopharma company that identifies, acquires, and accelerates the development and commercialization of life-changing therapies. *Founded* 2020 Los Angeles, United States **$300M** last round Sept 2022 - 28 [**Allakos** Allakos is a biotechnology company developing therapeutic antibodies targeting allergy, inflammatory and proliferative diseases.](https://millionrounds.com/company/allakos) Allakos is a biotechnology company developing therapeutic antibodies targeting allergy, inflammatory and proliferative diseases. *Founded* 2012 Redwood City, United States **$294M** last round Sept 2022 - 29 [**Arcellx** Arcellx is a clinical-stage biotechnology company focused on developing innovative immunotherapies for cancer and other incurable diseases.](https://millionrounds.com/company/arcellx) Arcellx is a clinical-stage biotechnology company focused on developing innovative immunotherapies for cancer and other incurable diseases. *Founded* 2015 Redwood City, United States **$285M** last round Nov 2023 - 30 [**Cullinan Therapeutics** Cullinan Therapeutics is a developer of an externally sourced cancer therapeutics used to end a drug program quickly.](https://millionrounds.com/company/cullinan-therapeutics) Cullinan Therapeutics is a developer of an externally sourced cancer therapeutics used to end a drug program quickly. *Founded* - Cambridge, United States **$280M** last round Apr 2024 - 31 [**Emalex Biosciences** Emalex Biosciences is a biotech startup that develops new treatments for central nervous system disorders.](https://millionrounds.com/company/emalex-biosciences) Emalex Biosciences is a biotech startup that develops new treatments for central nervous system disorders. *Founded* 2018 Chicago, United States **$270M** last round Nov 2022 - 32 [**Inhibrx**](https://millionrounds.com/company/inhibrx) *Founded* 2017 United States **$265M** last round Mar 2026 - 33 [**Capital Rx** Capital Rx, now rebranded as Judi Health, is a prominent enterprise health technology company specializing in pharmacy benefits management (PBM).](https://millionrounds.com/company/capital-rx) Capital Rx, now rebranded as Judi Health, is a prominent enterprise health technology company specializing in pharmacy benefits management (PBM). *Founded* 2017 New York, United States **$264M** last round Sept 2025 - 34 [**Compass Therapeutics** Compass Therapeutics is a biopharmaceutical company that focuses on drugging the immune system to treat human diseases.](https://millionrounds.com/company/compass-therapeutics) Compass Therapeutics is a biopharmaceutical company that focuses on drugging the immune system to treat human diseases. *Founded* 2014 Boston, United States **$257M** last round Aug 2025 - 35 [**Kardigan** Kardigan is a heart health company developing drugs designed to make cardiovascular disease curable, preventable, and no longer the leading cause of death.](https://millionrounds.com/company/kardigan) Kardigan is a heart health company developing drugs designed to make cardiovascular disease curable, preventable, and no longer the leading cause of death. *Founded* 2023 Princeton, United States **$254M** last round Oct 2025 - 36 [**LB Pharmaceuticals** LB Pharmaceuticals specializes in developing a treatment for schizophrenia.](https://millionrounds.com/company/lb-pharmaceuticals) LB Pharmaceuticals specializes in developing a treatment for schizophrenia. *Founded* 2015 Menlo Park, United States **$250M** last round Jul 2026 - 37 [**ORIC Pharmaceuticals** ORIC Pharmaceuticals is a biopharmaceutical company that develops treatments that target the causes of therapeutic resistance.](https://millionrounds.com/company/oric-pharmaceuticals) ORIC Pharmaceuticals is a biopharmaceutical company that develops treatments that target the causes of therapeutic resistance. *Founded* 2014 South San Francisco, United States **$248M** last round May 2025 - 38 [**Harmony Biosciences** Harmony Biosciences is a pharmaceutical company that develops and commercializes novel therapies for rare neurological disorders.](https://millionrounds.com/company/harmony-biosciences) Harmony Biosciences is a pharmaceutical company that develops and commercializes novel therapies for rare neurological disorders. *Founded* 2017 Plymouth Meeting, United States **$248M** last round Oct 2024 - 39 [**Arcutis Biotherapeutics** Arcutis Biotherapeutics is a clinical-stage biopharmaceutical company focused on developing medical dermatology for unmet needs.](https://millionrounds.com/company/arcutis-biotherapeutics) Arcutis Biotherapeutics is a clinical-stage biopharmaceutical company focused on developing medical dermatology for unmet needs. *Founded* 2016 Westlake Village, United States **$245M** last round Feb 2024 - 40 [**Aiolos Bio** Aiolos Bio is a biotech company developing innovative therapies for respiratory diseases and immune conditions.](https://millionrounds.com/company/aiolos-bio) Aiolos Bio is a biotech company developing innovative therapies for respiratory diseases and immune conditions. *Founded* 2023 London, United States **$245M** last round Oct 2023 - 41 [**Omni** Omni Metalcraft provides conveyors, replacement rollers, and components to manufacturing industries.](https://millionrounds.com/company/omni) Omni Metalcraft provides conveyors, replacement rollers, and components to manufacturing industries. *Founded* 1976 Alpena, United States **$244M** last round Nov 2026 - 42 [**Seaport Therapeutics** Seaport Therapeutics operates as a clinical stage biopharmaceutical company.](https://millionrounds.com/company/seaport-therapeutics) Seaport Therapeutics operates as a clinical stage biopharmaceutical company. *Founded* 2024 Boston, United States **$240M** last round Mar 2026 - 43 [**Zentalis Pharmaceuticals** Zentalis is a pharmaceutical company focused on developing clinical therapeutics for cancer patients.](https://millionrounds.com/company/zentalis-pharmaceuticals) Zentalis is a pharmaceutical company focused on developing clinical therapeutics for cancer patients. *Founded* - New York, United States **$236M** last round Jun 2023 - 44 [**City Therapeutics**](https://millionrounds.com/company/city-therapeutics) *Founded* - United States **$235M** last round Jun 2026 - 45 [**Roivant Sciences** Roivant aims to improve health by rapidly delivering innovative medicines and technologies to patients.](https://millionrounds.com/company/roivant-sciences) Roivant aims to improve health by rapidly delivering innovative medicines and technologies to patients. *Founded* - United States **$230M** last round Feb 2023 - 46 [**Solstice Oncology** Solstice Oncology develops immuno-oncology therapies focused on treating and preventing cancer through targeted approaches.](https://millionrounds.com/company/solstice-oncology) Solstice Oncology develops immuno-oncology therapies focused on treating and preventing cancer through targeted approaches. *Founded* - Boston, United States **$225M** last round Sept 2026 - 47 [**moksha8 Pharmaceuticals** Moksha8 is a pharmaceutical company providing therapeutics for the treatment of central nervous system and mental health disorders.](https://millionrounds.com/company/moksha8-pharmaceuticals) Moksha8 is a pharmaceutical company providing therapeutics for the treatment of central nervous system and mental health disorders. *Founded* 2007 Berwyn, United States **$224M** last round Oct 2012 - 48 [**Matchpoint Therapeutics** Matchpoint Therapeutics is a biotechnology company based in Cambridge, Massachusetts, founded in 2021.](https://millionrounds.com/company/matchpoint-therapeutics) Matchpoint Therapeutics is a biotechnology company based in Cambridge, Massachusetts, founded in 2021. *Founded* 2021 Cambridge, United States **$220M** last round Oct 2026 - 49 [**Poseida Therapeutics** Poseida Therapeutics is a biopharmaceutical company utilizing gene engineering capabilities to develop targeted therapeutics.](https://millionrounds.com/company/poseida-therapeutics) Poseida Therapeutics is a biopharmaceutical company utilizing gene engineering capabilities to develop targeted therapeutics. *Founded* 2014 San Diego, United States **$217M** last round Aug 2023 - 50 [**Metsera** Metsera operates as a clinical-stage biopharmaceutical company.](https://millionrounds.com/company/metsera) Metsera operates as a clinical-stage biopharmaceutical company. *Founded* 2022 New York City, United States **$215M** last round Nov 2024 **Total funding** how the list is ranked **15 November 2026** updated nightly **Rounds we track** source: Millionrounds Companies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list. ## Who backed them? Open any company for its rounds and investors, or search the investors who back pharma startups in the United States in the app, with filters, lists and exports. [Find their investors](https://millionrounds.com/login?join=1&next=/app/investors)[All top lists](https://millionrounds.com/top-lists) ## More pharma lists [See all](https://millionrounds.com/top-lists?t=Pharma) [*NR* *DT* *V* **Pharma startups that raised in 2026** 198 companies · $10B in 2026](https://millionrounds.com/top-lists/pharma-startups-raised-2026)[*C* *OT* *A* **Pharma startups in the United Kingdom** 76 companies · $4.0B](https://millionrounds.com/top-lists/pharma-startups-united-kingdom)[*MT* *DT* *QP* **Pharma startups founded in 2019** 63 companies · $3.5B](https://millionrounds.com/top-lists/pharma-startups-founded-2019)[*AL* *RB* *MT* **Pharma startups founded in 2021** 60 companies · $6.3B](https://millionrounds.com/top-lists/pharma-startups-founded-2021)[*I* *MT* *8* **Pharma startups founded in 2018** 58 companies · $4.5B](https://millionrounds.com/top-lists/pharma-startups-founded-2018)[*NR* *A* *BT* **Pharma startups founded in 2020** 57 companies · $3.5B](https://millionrounds.com/top-lists/pharma-startups-founded-2020)[*IP* *IT* *VT* **Pharma startups in France** 40 companies · $803M](https://millionrounds.com/top-lists/pharma-startups-france)[*M* *LB* *DT* **Pharma startups founded in 2022** 30 companies · $1.0B](https://millionrounds.com/top-lists/pharma-startups-founded-2022) ## More lists for United States [See all](https://millionrounds.com/top-lists?r=United%20States) [*O* *A* *X* **Startups in the United States** 42,176 companies · $870B](https://millionrounds.com/top-lists/startups-united-states)[*GV* *V* *RP* **Health startups in the United States** 7,411 companies · $71B](https://millionrounds.com/top-lists/health-startups-united-states)[*O* *A* *X* **AI startups in the United States** 5,656 companies · $718B](https://millionrounds.com/top-lists/ai-startups-united-states)[*V* *RP* *DH* **Healthcare startups in the United States** 4,148 companies · $51B](https://millionrounds.com/top-lists/healthcare-startups-united-states)[*S* *P* *I* **IT Services startups in the United States** 3,482 companies · $27B](https://millionrounds.com/top-lists/it-services-startups-united-states)[*D* *CE* *AD* **Big Data & Analytics startups in the United States** 2,107 companies · $132B](https://millionrounds.com/top-lists/big-data-startups-united-states)[*O* *A* *W* **AI startups in the United States that raised in 2026** 1,648 companies · $431B in 2026](https://millionrounds.com/top-lists/ai-startups-united-states-raised-2026)[*D* *P* *A* **Software startups in the United States** 1,638 companies · $77B](https://millionrounds.com/top-lists/software-startups-united-states)