# Top 10 Pharma Startups in South San Francisco by Funding (2026)

> The 10 best-funded pharma startups in South San Francisco, ranked by total funding raised: $1.3B combined.

Source: https://millionrounds.com/top-lists/pharma-startups-south-san-francisco (Millionrounds; every figure on the page links to its filing or article)

- 1 [**NGM Biopharmaceuticals** NGM Biopharmaceuticals Inc.](https://millionrounds.com/company/ngm-biopharmaceuticals) NGM Biopharmaceuticals Inc. *Founded* 2008 South San Francisco, United States **$333M** last round Mar 2015
- 2 [**Maze Therapeutics** Maze Therapeutics is an operator of a biotechnology firm used to focus on translating genetic insights into new medicines.](https://millionrounds.com/company/maze-therapeutics) Maze Therapeutics is an operator of a biotechnology firm used to focus on translating genetic insights into new medicines. *Founded* 2018 South San Francisco, United States **$300M** last round Apr 2026
- 3 [**ORIC Pharmaceuticals** ORIC Pharmaceuticals is a biopharmaceutical company that develops treatments that target the causes of therapeutic resistance.](https://millionrounds.com/company/oric-pharmaceuticals) ORIC Pharmaceuticals is a biopharmaceutical company that develops treatments that target the causes of therapeutic resistance. *Founded* 2014 South San Francisco, United States **$248M** last round May 2025
- 4 [**Day One Biopharmaceuticals** Day One Biopharmaceuticals develops targeted therapies to treat people with life-threatening diseases.](https://millionrounds.com/company/day-one-biopharmaceuticals) Day One Biopharmaceuticals develops targeted therapies to treat people with life-threatening diseases. *Founded* 2018 South San Francisco, United States **$175M** last round Jul 2024
- 5 [**Cartography Biosciences** Cartography Biosciences is a biotechnology company based in South San Francisco, CA, focused on precision immunotherapy and therapeutics.](https://millionrounds.com/company/cartography-biosciences) Cartography Biosciences is a biotechnology company based in South San Francisco, CA, focused on precision immunotherapy and therapeutics. *Founded* 2020 South San Francisco, United States **$67M** last round May 2026
- 6 [**Spruce Biosciences** Spruce Biosciences is a biopharmaceutical company developing therapies for rare diseases that target the endocrine system.](https://millionrounds.com/company/spruce-biosciences) Spruce Biosciences is a biopharmaceutical company developing therapies for rare diseases that target the endocrine system. *Founded* 2016 South San Francisco, United States **$60M** last round Apr 2026
- 7 [**Novome Biotechnologies** Novome Biotechnologies is a clinical-stage biotechnology company located in South San Francisco, California.](https://millionrounds.com/company/novome-biotechnologies) Novome Biotechnologies is a clinical-stage biotechnology company located in South San Francisco, California. *Founded* 2016 South San Francisco, United States **$44M** last round Sept 2022
- 8 [**Noetik** Noetik is an AI-native biotechnology company based in South San Francisco, California, founded in 2022.](https://millionrounds.com/company/noetik) Noetik is an AI-native biotechnology company based in South San Francisco, California, founded in 2022. *Founded* 2022 South San Francisco, United States **$41M** last round Sept 2024
- 9 [**3T Biosciences** 3T Biosciences is an immunotherapy company based in South San Francisco, California, founded in 2017.](https://millionrounds.com/company/3t-biosciences) 3T Biosciences is an immunotherapy company based in South San Francisco, California, founded in 2017. *Founded* 2017 South San Francisco, United States **$40M** last round Aug 2022
- 10 [**Validfor** Validfor is an AI-native digital validation platform designed for regulated life sciences, particularly serving pharmaceutical, biotechnology, and medical devic](https://millionrounds.com/company/validfor) Validfor is an AI-native digital validation platform designed for regulated life sciences, particularly serving pharmaceutical, biotechnology, and medical devic *Founded* 2025 South San Francisco, United States **$1.2M** last round Feb 2026

**Total funding** how the list is ranked

**15 November 2026** updated nightly

**Rounds we track** source: Millionrounds

Companies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.

## Who backed them?

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[Find their investors](https://millionrounds.com/login?join=1&next=/app/investors)[All top lists](https://millionrounds.com/top-lists)

## More pharma lists

[See all](https://millionrounds.com/top-lists?t=Pharma)

[*AL* *NR* *RB* **Pharma startups in the United States** 540 companies · $23B](https://millionrounds.com/top-lists/pharma-startups-united-states)[*NR* *DT* *V* **Pharma startups that raised in 2026** 198 companies · $10B in 2026](https://millionrounds.com/top-lists/pharma-startups-raised-2026)[*C* *OT* *A* **Pharma startups in the United Kingdom** 76 companies · $4.0B](https://millionrounds.com/top-lists/pharma-startups-united-kingdom)[*MT* *DT* *QP* **Pharma startups founded in 2019** 63 companies · $3.5B](https://millionrounds.com/top-lists/pharma-startups-founded-2019)[*AL* *RB* *MT* **Pharma startups founded in 2021** 60 companies · $6.3B](https://millionrounds.com/top-lists/pharma-startups-founded-2021)[*I* *MT* *8* **Pharma startups founded in 2018** 58 companies · $4.5B](https://millionrounds.com/top-lists/pharma-startups-founded-2018)[*NR* *A* *BT* **Pharma startups founded in 2020** 57 companies · $3.5B](https://millionrounds.com/top-lists/pharma-startups-founded-2020)[*IP* *IT* *VT* **Pharma startups in France** 40 companies · $803M](https://millionrounds.com/top-lists/pharma-startups-france)

## More lists for South San Francisco

[See all](https://millionrounds.com/top-lists?r=South%20San%20Francisco)

[*V* *XT* *ST* **Startups in South San Francisco** 126 companies · $14B](https://millionrounds.com/top-lists/startups-south-san-francisco)[*V* *ST* *N* **Biotech startups in South San Francisco** 81 companies · $12B](https://millionrounds.com/top-lists/biotech-startups-south-san-francisco)[*V* *F* *A* **Healthcare startups in South San Francisco** 31 companies · $5.9B](https://millionrounds.com/top-lists/healthcare-startups-south-san-francisco)[*V* *XT* *I* **AI startups in South San Francisco** 16 companies · $2.9B](https://millionrounds.com/top-lists/ai-startups-south-san-francisco)