# Top 50 Medical Devices Startups in the United States by Funding (2026)

> The 50 best-funded medical Devices startups in the United States, ranked by total funding raised: $11B combined.

Source: https://millionrounds.com/top-lists/medical-device-startups-united-states (Millionrounds; every figure on the page links to its filing or article)

- 1 [**Grail**](https://millionrounds.com/company/grail) *Founded* - United States **$1.6B** last round Jun 2026
- 2 [**Neuralink** Neuralink develops a brain machine interface that provides solutions for those with paralysis.](https://millionrounds.com/company/neuralink) Neuralink develops a brain machine interface that provides solutions for those with paralysis. *Founded* 2016 Fremont, United States **$882M** last round May 2026
- 3 [**Mevion Medical Systems** Mevion Medical Systems develops radiation therapies for the treatment of cancer.](https://millionrounds.com/company/mevion-medical-systems) Mevion Medical Systems develops radiation therapies for the treatment of cancer. *Founded* 2004 Littleton, United States **$435M** last round Aug 2015
- 4 [**Sharps Technology** Sharps Technology is an innovative medical device company.](https://millionrounds.com/company/sharps-technology) Sharps Technology is an innovative medical device company. *Founded* 2017 United States **$411M** last round Nov 2025
- 5 [**Cleerly** Cleerly is a digital healthcare technology company based in Denver, founded in 2017.](https://millionrounds.com/company/cleerly) Cleerly is a digital healthcare technology company based in Denver, founded in 2017. *Founded* 2017 Denver, United States **$372M** last round Dec 2024
- 6 [**CVRx** CVRx is a medical device company developing implantable technology for the treatment of high blood pressure.](https://millionrounds.com/company/cvrx) CVRx is a medical device company developing implantable technology for the treatment of high blood pressure. *Founded* 2001 Minneapolis, United States **$369M** last round Jul 2020
- 7 [**Precision Neuroscience** Precision Neuroscience is a neurotechnology startup based in New York City, founded in 2021.](https://millionrounds.com/company/precision-neuroscience) Precision Neuroscience is a neurotechnology startup based in New York City, founded in 2021. *Founded* 2021 New York, United States **$352M** last round Sept 2026
- 8 [**ConforMIS** ConforMIS develops personalized, patient-specific implants, and instrumentation for knee-related therapeutics.](https://millionrounds.com/company/conformis) ConforMIS develops personalized, patient-specific implants, and instrumentation for knee-related therapeutics. *Founded* 2004 Billerica, United States **$319M** last round Aug 2013
- 9 [**Synchron** Synchron is a neurotechnology company located in Brooklyn, New York.](https://millionrounds.com/company/synchron) Synchron is a neurotechnology company located in Brooklyn, New York. *Founded* 2016 New York, United States **$310M** last round Nov 2025
- 10 [**BillionToOne** BillionToOne is a precision diagnostics company that focuses on genetic testing for disease detection.](https://millionrounds.com/company/billiontoone) BillionToOne is a precision diagnostics company that focuses on genetic testing for disease detection. *Founded* - Menlo Park, United States **$280M** last round Sept 2024
- 11 [**Endogenex** Endogenex is a clinical-stage medical technology company based in Plymouth, Minnesota, founded in 2017 in partnership with Mayo Clinic.](https://millionrounds.com/company/endogenex) Endogenex is a clinical-stage medical technology company based in Plymouth, Minnesota, founded in 2017 in partnership with Mayo Clinic. *Founded* 2017 Minneapolis, United States **$270M** last round Nov 2026
- 12 [**TriVascular** TriVascular develops new medical devices providing optimal solutions for endovascular aortic repair (EVAR).](https://millionrounds.com/company/trivascular) TriVascular develops new medical devices providing optimal solutions for endovascular aortic repair (EVAR). *Founded* 1998 Santa Rosa, United States **$267M** last round Aug 2015
- 13 [**SetPoint Medical** SetPoint Medical is a commercial-stage medical technology company founded in 2007, focused on developing bioelectronic therapies for chronic autoimmune conditions.](https://millionrounds.com/company/setpoint-medical) SetPoint Medical is a commercial-stage medical technology company founded in 2007, focused on developing bioelectronic therapies for chronic autoimmune conditions. *Founded* 2007 Santa Clarita, United States **$256M** last round Aug 2025
- 14 [**HistoSonics, Inc.** HistoSonics, Inc.](https://millionrounds.com/company/histosonics-inc) HistoSonics, Inc. *Founded* 2009 Plymouth, United States **$250M** last round Oct 2025
- 15 [**Relievant Medsystems** Relievant Medsystems is a medical device company specializing in diagnosing and treating chronic low back pain.](https://millionrounds.com/company/relievant-medsystems) Relievant Medsystems is a medical device company specializing in diagnosing and treating chronic low back pain. *Founded* 2006 Minneapolis, United States **$211M** last round Apr 2023
- 16 [**AxoGen** Axogen is the leading company focused specifically on the science, development and commercialization of technologies for peripheral nerve regeneration and repair.](https://millionrounds.com/company/axogen) Axogen is the leading company focused specifically on the science, development and commercialization of technologies for peripheral nerve regeneration and repair. *Founded* 2002 Alachua, United States **$198M** last round Jan 2026
- 17 [**HistoSonics** HistoSonics specializes in developing non-invasive medical devices, interventional radiology, and surgical robotics.](https://millionrounds.com/company/histosonics) HistoSonics specializes in developing non-invasive medical devices, interventional radiology, and surgical robotics. *Founded* 2009 Plymouth, United States **$197M** last round Jun 2026
- 18 [**TearScience** TearScience develops devices that provide significant clinical identification and treatment of evaporative dry eye.](https://millionrounds.com/company/tearscience) TearScience develops devices that provide significant clinical identification and treatment of evaporative dry eye. *Founded* 2005 Morrisville, United States **$185M** last round Feb 2013
- 19 [**Alleviant Medical** Alleviant Medical is a medical device company based in Austin, Texas, founded in 2017.](https://millionrounds.com/company/alleviant-medical) Alleviant Medical is a medical device company based in Austin, Texas, founded in 2017. *Founded* 2017 Austin, United States **$165M** last round Jan 2025
- 20 [**Epic Sciences** Epic Sciences is a diagnostics company improving cancer management by providing real-time biopsy material to guide personalized medicine.](https://millionrounds.com/company/epic-sciences) Epic Sciences is a diagnostics company improving cancer management by providing real-time biopsy material to guide personalized medicine. *Founded* 2008 San Diego, United States **$165M** last round Apr 2023
- 21 [**Laza Medical** Laza Medical is a healthcare technology company focused on enhancing cardiac procedures through advanced imaging solutions.](https://millionrounds.com/company/laza-medical) Laza Medical is a healthcare technology company focused on enhancing cardiac procedures through advanced imaging solutions. *Founded* 2020 Los Gatos, United States **$160M** last round Nov 2026
- 22 [**CereVasc** CereVasc is a clinical-stage medical device company based in Boston, Massachusetts, focused on developing innovative, minimally invasive treatments for neurolog](https://millionrounds.com/company/cerevasc) CereVasc is a clinical-stage medical device company based in Boston, Massachusetts, focused on developing innovative, minimally invasive treatments for neurolog *Founded* 2013 Boston, United States **$155M** last round Jun 2026
- 23 [**Medical Microinstruments**](https://millionrounds.com/company/medical-microinstruments) *Founded* - United States **$150M** last round Nov 2026
- 24 [**Personal Genome Diagnostics** Personal Genome Diagnostics develops a patient-specific analysis of the cancer genome by using advanced tools and technologies.](https://millionrounds.com/company/personal-genome-diagnostics) Personal Genome Diagnostics develops a patient-specific analysis of the cancer genome by using advanced tools and technologies. *Founded* 2010 Salinas, United States **$145M** last round Feb 2021
- 25 [**Axonics Modulation Technologies** Axonics Modulation Technologies is a pre-revenue company developing novel implantable neuromodulation.](https://millionrounds.com/company/axonics-modulation-technologies) Axonics Modulation Technologies is a pre-revenue company developing novel implantable neuromodulation. *Founded* 2012 Irvine, United States **$144M** last round Aug 2022
- 26 [**CardioKinetix** Cardiokinetix is a medical device company based in Menlo Park, California, focused on improving cardiac function for patients with ischemic heart failure.](https://millionrounds.com/company/cardiokinetix) Cardiokinetix is a medical device company based in Menlo Park, California, focused on improving cardiac function for patients with ischemic heart failure. *Founded* 2002 Menlo Park, United States **$136M** last round Dec 2014
- 27 [**Augury** Augury is an Industrial AI and Machine Health company that offers AI-driven solutions for manufacturers and industrial firms.](https://millionrounds.com/company/augury) Augury is an Industrial AI and Machine Health company that offers AI-driven solutions for manufacturers and industrial firms. *Founded* 2011 New York, United States **$134M** last round Feb 2025
- 28 [**Apreo Health** Apreo Health is a clinical-stage medical device company based in Menlo Park, California, founded in 2021.](https://millionrounds.com/company/apreo-health) Apreo Health is a clinical-stage medical device company based in Menlo Park, California, founded in 2021. *Founded* - Menlo Park, United States **$130M** last round May 2026
- 29 [**Hansen Medical** Hansen Medical focuses on robotic-assisted bronchoscopy for minimally invasive lung procedures.](https://millionrounds.com/company/hansen-medical) Hansen Medical focuses on robotic-assisted bronchoscopy for minimally invasive lung procedures. *Founded* 2002 Mountain View, United States **$116M** last round Mar 2015
- 30 [**GT Medical Technologies** GT Medical Technologies provides surgically targeted radiation therapy to individuals with operable brain tumors.](https://millionrounds.com/company/gt-medical-technologies) GT Medical Technologies provides surgically targeted radiation therapy to individuals with operable brain tumors. *Founded* 2017 Tempe, United States **$110M** last round Jun 2026
- 31 [**Promaxo** Promaxo is a medical technology company based in Oakland, California, founded in 2016.](https://millionrounds.com/company/promaxo) Promaxo is a medical technology company based in Oakland, California, founded in 2016. *Founded* 2016 Oakland, United States **$106M** last round Oct 2026
- 32 [**Xoft** Xoft develops electronic brachytherapy (eBx) systems for radiation oncology applications.](https://millionrounds.com/company/xoft) Xoft develops electronic brachytherapy (eBx) systems for radiation oncology applications. *Founded* 1998 San Jose, United States **$100M** last round Jul 2010
- 33 [**Active Implants** Active Implants develops cushion-bearing orthopedic implant solutions.](https://millionrounds.com/company/active-implants) Active Implants develops cushion-bearing orthopedic implant solutions. *Founded* 2004 Memphis, United States **$100M** last round Aug 2013
- 34 [**LightForce Orthodontics** Lightforce Orthodontics is a fully customized 3D-printed bracket system developer based on the anatomy and tooth morphology of each patient.](https://millionrounds.com/company/lightforce-orthodontics) Lightforce Orthodontics is a fully customized 3D-printed bracket system developer based on the anatomy and tooth morphology of each patient. *Founded* 2015 Burlington, United States **$94M** last round Aug 2023
- 35 [**Elucid** Elucid enables precision medicine for cardiovascular disease by applying A.I to medical image analysis validated against true biology.](https://millionrounds.com/company/elucid) Elucid enables precision medicine for cardiovascular disease by applying A.I to medical image analysis validated against true biology. *Founded* 2013 Boston, United States **$92M** last round Sept 2026
- 36 [**GT Medical Technologies, Inc.** GT Medical Technologies, Inc.](https://millionrounds.com/company/gt-medical-technologies-inc) GT Medical Technologies, Inc. *Founded* 2017 Tempe, United States **$82M** last round Jan 2025
- 37 [**NinePoint Medical** NinePoint Medical is a transformational medical device company developing innovative, real-time, in vivo pathology devices.](https://millionrounds.com/company/ninepoint-medical) NinePoint Medical is a transformational medical device company developing innovative, real-time, in vivo pathology devices. *Founded* 2008 Bedford, United States **$82M** last round Feb 2015
- 38 [**Spiration** Spiration is a developer of therapeutic medical devices for the treatment of air leaks and lung diseases.](https://millionrounds.com/company/spiration) Spiration is a developer of therapeutic medical devices for the treatment of air leaks and lung diseases. *Founded* 1999 Center Valley, United States **$81M** last round Apr 2010
- 39 [**OmniGuide** OmniGuide is a medical device company developing and commercializing minimally-invasive surgical tools.](https://millionrounds.com/company/omniguide) OmniGuide is a medical device company developing and commercializing minimally-invasive surgical tools. *Founded* 2000 Billerica, United States **$81M** last round Sept 2013
- 40 [**Transcend Medical** Transcend Medical focuses on the research and development of novel devices for the treatment of glaucoma.](https://millionrounds.com/company/transcend-medical) Transcend Medical focuses on the research and development of novel devices for the treatment of glaucoma. *Founded* 2005 Menlo Park, United States **$80M** last round Apr 2014
- 41 [**Endovascular Engineering, Inc. (“E2”)**](https://millionrounds.com/company/endovascular-engineering-inc-e2) *Founded* - United States **$80M** last round Apr 2026
- 42 [**Okami Medical** Okami Medical develops and commercializes new devices for the treatment of heart disease.](https://millionrounds.com/company/okami-medical) Okami Medical develops and commercializes new devices for the treatment of heart disease. *Founded* 2011 Boston, United States **$78M** last round Nov 2025
- 43 [**OrthoSensor** OrthoSensor is a medical device company developing devices and data services for the orthopedic sector.](https://millionrounds.com/company/orthosensor) OrthoSensor is a medical device company developing devices and data services for the orthopedic sector. *Founded* 2006 Dania, United States **$76M** last round Mar 2015
- 44 [**GreatCall** Lively, formerly known as GreatCall, is a prominent provider of connected health and personal emergency response services aimed at older adults and vulnerable individuals.](https://millionrounds.com/company/greatcall) Lively, formerly known as GreatCall, is a prominent provider of connected health and personal emergency response services aimed at older adults and vulnerable individuals. *Founded* 2006 San Diego, United States **$75M** last round Jun 2012
- 45 [**Cagent Vascular** Cagent Vascular is a medical device company based in Wayne, Pennsylvania, focused on advancing treatment for Peripheral Artery Disease (PAD) and Chronic Limb-Th](https://millionrounds.com/company/cagent-vascular) Cagent Vascular is a medical device company based in Wayne, Pennsylvania, focused on advancing treatment for Peripheral Artery Disease (PAD) and Chronic Limb-Th *Founded* 2014 Wayne, United States **$68M** last round May 2026
- 46 [**MC10** MC10 develops virtually invisible, conformal electronics that reshape rigid conventional electronics into thin flexible devices.](https://millionrounds.com/company/mc10) MC10 develops virtually invisible, conformal electronics that reshape rigid conventional electronics into thin flexible devices. *Founded* 2008 Boston, United States **$67M** last round Jan 2014
- 47 [**SurgiQuest** SurgiQuest is a surgical device company in the field of minimally-invasive access technology.](https://millionrounds.com/company/surgiquest) SurgiQuest is a surgical device company in the field of minimally-invasive access technology. *Founded* 2006 Milford, United States **$65M** last round Mar 2015
- 48 [**Sequent Medical** Sequent Medical is a medical device company based in Aliso Viejo, California, founded in 2007.](https://millionrounds.com/company/sequent-medical) Sequent Medical is a medical device company based in Aliso Viejo, California, founded in 2007. *Founded* 2007 Aliso Viejo, United States **$65M** last round Apr 2014
- 49 [**Ardian** Ardian is a developer of catheter-based therapies for hypertension treatment.](https://millionrounds.com/company/ardian) Ardian is a developer of catheter-based therapies for hypertension treatment. *Founded* - Mountain View, United States **$64M** last round Mar 2009
- 50 [**Route 92 Medical** Route 92 Medical is a medical device company developing a catheter to treat stroke.](https://millionrounds.com/company/route-92-medical) Route 92 Medical is a medical device company developing a catheter to treat stroke. *Founded* 2015 San Mateo, United States **$63M** last round Apr 2026

**Total funding** how the list is ranked

**15 November 2026** updated nightly

**Rounds we track** source: Millionrounds

Companies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.

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## More medical devices lists

[See all](https://millionrounds.com/top-lists?t=Medical%20Devices)

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