# Top 19 Healthcare Startups in San Mateo by Funding (2026)

> The 19 best-funded healthcare startups in San Mateo, ranked by total funding raised: $939M combined. With founding year, headquarters and each company's rounds.

Source: https://millionrounds.com/top-lists/healthcare-startups-san-mateo (Millionrounds; every figure on the page links to its filing or article)

- 1 [**Luma Health** Luma Health is a healthcare technology company founded in 2015 and based in San Mateo, California.](https://millionrounds.com/company/luma-health) Luma Health is a healthcare technology company founded in 2015 and based in San Mateo, California. *Founded* 2015 San Mateo, United States **$152M** last round Nov 2021
- 2 [**Cala Health** Cala Health is a bioelectronic medicine company based in San Mateo, California, founded in 2013.](https://millionrounds.com/company/cala-health) Cala Health is a bioelectronic medicine company based in San Mateo, California, founded in 2013. *Founded* 2014 San Mateo, United States **$150M** last round Apr 2026
- 3 [**Notable** Notable is an AI-powered health start-up that automates and digitizes every physician-patient interaction.](https://millionrounds.com/company/notable) Notable is an AI-powered health start-up that automates and digitizes every physician-patient interaction. *Founded* 2017 San Mateo, United States **$145M** last round Jul 2026
- 4 [**Salma Health** Salma Health is a comprehensive brain health clinic combining advanced diagnostics, personalized treatment and continuous care under one roof.](https://millionrounds.com/company/salma-health) Salma Health is a comprehensive brain health clinic combining advanced diagnostics, personalized treatment and continuous care under one roof. *Founded* 2016 San Mateo, United States **$80M** last round Feb 2026
- 5 [**Vivace Therapeutics** Vivace Therapeutics is a venture-backed start-up dedicated to discovering and developing cancer therapeutics by targeting a novel pathway.](https://millionrounds.com/company/vivace-therapeutics) Vivace Therapeutics is a venture-backed start-up dedicated to discovering and developing cancer therapeutics by targeting a novel pathway. *Founded* 2014 San Mateo, United States **$75M** last round Mar 2025
- 6 [**Sonitus Medical** Sonitus Medical provides clinically effective non-invasive and removable hearing solutions based on the bone conduction method.](https://millionrounds.com/company/sonitus-medical) Sonitus Medical provides clinically effective non-invasive and removable hearing solutions based on the bone conduction method. *Founded* 2006 San Mateo, United States **$68M** last round Apr 2014
- 7 [**Route 92 Medical** Route 92 Medical is a medical device company developing a catheter to treat stroke.](https://millionrounds.com/company/route-92-medical) Route 92 Medical is a medical device company developing a catheter to treat stroke. *Founded* 2015 San Mateo, United States **$63M** last round Apr 2026
- 8 [**Evidation Health** We enable and empower everyone to participate in better health outcomes.](https://millionrounds.com/company/evidation-health) We enable and empower everyone to participate in better health outcomes. *Founded* 2012 San Mateo, United States **$61M** last round Aug 2018
- 9 [**Health Fidelity** Health Fidelity offers risk adjustment and quality solutions for healthcare organizations participating in risk-based payment programs.](https://millionrounds.com/company/health-fidelity) Health Fidelity offers risk adjustment and quality solutions for healthcare organizations participating in risk-based payment programs. *Founded* 2011 San Mateo, United States **$39M** last round Jan 2015
- 10 [**Sagimet Biosciences** Sagimet Biosciences is a biotechnology company that focuses on developing novel therapeutics to treat important diseases.](https://millionrounds.com/company/sagimet-biosciences) Sagimet Biosciences is a biotechnology company that focuses on developing novel therapeutics to treat important diseases. *Founded* 2007 San Mateo, United States **$25M** last round Aug 2019
- 11 [**Lumiata** Lumiata was a healthcare-focused artificial intelligence company founded in 2013 in San Mateo, California.](https://millionrounds.com/company/lumiata) Lumiata was a healthcare-focused artificial intelligence company founded in 2013 in San Mateo, California. *Founded* 2013 San Mateo, United States **$21M** last round Jul 2018
- 12 [**Opya** Opya is a healthcare technology company based in San Mateo, California, focused on early intervention autism therapy for children aged 18 months to 6 years who](https://millionrounds.com/company/opya) Opya is a healthcare technology company based in San Mateo, California, focused on early intervention autism therapy for children aged 18 months to 6 years who *Founded* 2015 San Mateo, United States **$15M** last round Aug 2021
- 13 [**SonoMotion** Sonomotion is a medical device manufacturing company that specializes in providing medical solutions for kidney stones disease.](https://millionrounds.com/company/sonomotion) Sonomotion is a medical device manufacturing company that specializes in providing medical solutions for kidney stones disease. *Founded* 2014 San Mateo, United States **$12M** last round Feb 2025
- 14 [**Trek Health** Trek Health is an AI-powered healthcare software platform based in San Mateo, California, founded in 2021.](https://millionrounds.com/company/trek-health) Trek Health is an AI-powered healthcare software platform based in San Mateo, California, founded in 2021. *Founded* 2022 San Mateo, United States **$11M** last round Apr 2025
- 15 [**Vynca** Vynca, also known as VyncaCare, is a healthcare technology company based in San Mateo, California.](https://millionrounds.com/company/vynca) Vynca, also known as VyncaCare, is a healthcare technology company based in San Mateo, California. *Founded* 2014 San Mateo, United States **$10M** last round Jun 2019
- 16 [**Frame** Frame has merged with Dizzion!](https://millionrounds.com/company/frame) Frame has merged with Dizzion! *Founded* 2012 San Mateo, United States **$8.8M** last round Sept 2026
- 17 [**Storii** Software for Senior Care](https://millionrounds.com/company/storii) Software for Senior Care *Founded* 2016 San Mateo, United States **$1.7M** last round Nov 2025
- 18 [**Luminate Health** Luminate Health provides a SaaS-based solution that enables patients to access, manage, and understand their lab results.](https://millionrounds.com/company/luminate-health) Luminate Health provides a SaaS-based solution that enables patients to access, manage, and understand their lab results. *Founded* 2013 San Mateo, United States **$1.0M** last round Oct 2013
- 19 [**Globevestor** Globevestor is a cross-border venture capital firm and online investment platform founded in 2013, based in San Mateo, California.](https://millionrounds.com/company/globevestor) Globevestor is a cross-border venture capital firm and online investment platform founded in 2013, based in San Mateo, California. *Founded* 2013 San Mateo, United States **$25K** last round Feb 2014

**Total funding** how the list is ranked

**15 November 2026** updated nightly

**Rounds we track** source: Millionrounds

Companies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.

## Who backed them?

Open any company for its rounds and investors, or search the investors who back healthcare startups in San Mateo in the app, with filters, lists and exports.

[Find their investors](https://millionrounds.com/login?join=1&next=/app/investors)[All top lists](https://millionrounds.com/top-lists)

## More healthcare lists

[See all](https://millionrounds.com/top-lists?t=Healthcare)

[*V* *RP* *DH* **Healthcare startups in the United States** 4,148 companies · $51B](https://millionrounds.com/top-lists/healthcare-startups-united-states)[*IL* *RM* *NH* **Healthcare startups that raised in 2026** 879 companies · $25B in 2026](https://millionrounds.com/top-lists/healthcare-startups-raised-2026)[*IL* *CS* *ON* **Healthcare startups in the United Kingdom** 608 companies · $14B](https://millionrounds.com/top-lists/healthcare-startups-united-kingdom)[*RM* *AH* *B* **Healthcare startups in the United States that raised in 2026** 503 companies · $18B in 2026](https://millionrounds.com/top-lists/healthcare-startups-united-states-raised-2026)[*NH* *DT* *E* **Healthcare startups founded in 2018** 400 companies · $12B](https://millionrounds.com/top-lists/healthcare-startups-founded-2018)[*AH* *TC* *LL* **Healthcare startups founded in 2020** 385 companies · $3.8B](https://millionrounds.com/top-lists/healthcare-startups-founded-2020)[*AH* *CR* *V* **Healthcare startups founded in 2019** 380 companies · $11B](https://millionrounds.com/top-lists/healthcare-startups-founded-2019)[*IL* *E* *O* **Healthcare startups founded in 2021** 304 companies · $10B](https://millionrounds.com/top-lists/healthcare-startups-founded-2021)

## More lists for San Mateo

[See all](https://millionrounds.com/top-lists?r=San%20Mateo)

[*S* *FA* *U* **Startups in San Mateo** 254 companies · $16B](https://millionrounds.com/top-lists/startups-san-mateo)[*S* *FA* *U* **AI startups in San Mateo** 48 companies · $12B](https://millionrounds.com/top-lists/ai-startups-san-mateo)[*I* *B* *S* **IT Services startups in San Mateo** 32 companies · $410M](https://millionrounds.com/top-lists/it-services-startups-san-mateo)[*S* *C* *S* **Big Data & Analytics startups in San Mateo** 29 companies · $6.1B](https://millionrounds.com/top-lists/big-data-startups-san-mateo)[*BT* *LH* *BB* **Biotech startups in San Mateo** 22 companies · $1.5B](https://millionrounds.com/top-lists/biotech-startups-san-mateo)[*FA* *O* *T* **Software startups in San Mateo** 22 companies · $2.4B](https://millionrounds.com/top-lists/software-startups-san-mateo)[*R* *T* *N* **Internet startups in San Mateo** 11 companies · $504M](https://millionrounds.com/top-lists/internet-startups-san-mateo)[*V* *V* *AL* **Cybersecurity startups in San Mateo** 10 companies · $1.9B](https://millionrounds.com/top-lists/cybersecurity-startups-san-mateo)