# Top 10 Healthcare Startups in Cleveland by Funding (2026)

> The 10 best-funded healthcare startups in Cleveland, ranked by total funding raised: $150M combined. With founding year, headquarters and each company's rounds.

Source: https://millionrounds.com/top-lists/healthcare-startups-cleveland (Millionrounds; every figure on the page links to its filing or article)

- 1 [**SPR Therapeutics** SPR Therapeutics is a medical device company.](https://millionrounds.com/company/spr-therapeutics) SPR Therapeutics is a medical device company. *Founded* 2010 Cleveland, United States **$101M** last round Feb 2024
- 2 [**Checkpoint Surgical** Checkpoint Surgical provides physicians with medical devices to locate, evaluate, and protect nerves and muscles in surgical procedures.](https://millionrounds.com/company/checkpoint-surgical) Checkpoint Surgical provides physicians with medical devices to locate, evaluate, and protect nerves and muscles in surgical procedures. *Founded* 2009 Cleveland, United States **$23M** last round Jun 2024
- 3 [**Complion** Complion is a clinical research software company based in Cleveland, Ohio, founded in 2013.](https://millionrounds.com/company/complion) Complion is a clinical research software company based in Cleveland, Ohio, founded in 2013. *Founded* 2013 Cleveland, United States **$8.7M** last round Feb 2019
- 4 [**TandemStride** TandemStride is a trauma recovery support company focused on helping individuals recover from traumatic injuries.](https://millionrounds.com/company/tandemstride) TandemStride is a trauma recovery support company focused on helping individuals recover from traumatic injuries. *Founded* 2023 Cleveland, United States **$5.5M** last round Sept 2025
- 5 [**S4 Medical** S4 Medical Corp is a Cleveland-based medical device company founded in 2017.](https://millionrounds.com/company/s4-medical) S4 Medical Corp is a Cleveland-based medical device company founded in 2017. *Founded* 2017 Cleveland, United States **$5.0M** last round Jul 2023
- 6 [**Great Lakes NeuroTechnologies Inc.** Pioneering innovative biomedical technologies](https://millionrounds.com/company/great-lakes-neurotechnologies-inc) Pioneering innovative biomedical technologies *Founded* 2010 Cleveland, United States **$2.1M** last round Aug 2025
- 7 [**KeborMed** KeborMed is a healthcare technology company based in Cleveland, Ohio.](https://millionrounds.com/company/kebormed) KeborMed is a healthcare technology company based in Cleveland, Ohio. *Founded* 2017 Cleveland, United States **$1.9M** last round May 2022
- 8 [**TPA Stream** TPA Stream is a SaaS company that delivers cloud-based claims data and software for next generation benefits.](https://millionrounds.com/company/tpa-stream) TPA Stream is a SaaS company that delivers cloud-based claims data and software for next generation benefits. *Founded* 2014 Cleveland, United States **$1.4M** last round Sept 2019
- 9 [**CollaMedix** CollaMedix develops medical devices for treating urinary incontinence in women.](https://millionrounds.com/company/collamedix) CollaMedix develops medical devices for treating urinary incontinence in women. *Founded* 2018 Cleveland, United States **$988K** last round Aug 2021
- 10 [**Renalis** Renalis is a digital health company that develop platforms to improve experiences and outcomes for people with pelvic health conditions.](https://millionrounds.com/company/renalis) Renalis is a digital health company that develop platforms to improve experiences and outcomes for people with pelvic health conditions. *Founded* 2017 Cleveland, United States **$100K** last round Dec 2022

**Total funding** how the list is ranked

**15 November 2026** updated nightly

**Rounds we track** source: Millionrounds

Companies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.

## Who backed them?

Open any company for its rounds and investors, or search the investors who back healthcare startups in Cleveland in the app, with filters, lists and exports.

[Find their investors](https://millionrounds.com/login?join=1&next=/app/investors)[All top lists](https://millionrounds.com/top-lists)

## More healthcare lists

[See all](https://millionrounds.com/top-lists?t=Healthcare)

[*V* *RP* *DH* **Healthcare startups in the United States** 4,148 companies · $51B](https://millionrounds.com/top-lists/healthcare-startups-united-states)[*IL* *RM* *NH* **Healthcare startups that raised in 2026** 879 companies · $25B in 2026](https://millionrounds.com/top-lists/healthcare-startups-raised-2026)[*IL* *CS* *ON* **Healthcare startups in the United Kingdom** 608 companies · $14B](https://millionrounds.com/top-lists/healthcare-startups-united-kingdom)[*RM* *AH* *B* **Healthcare startups in the United States that raised in 2026** 503 companies · $18B in 2026](https://millionrounds.com/top-lists/healthcare-startups-united-states-raised-2026)[*NH* *DT* *E* **Healthcare startups founded in 2018** 400 companies · $12B](https://millionrounds.com/top-lists/healthcare-startups-founded-2018)[*AH* *TC* *LL* **Healthcare startups founded in 2020** 385 companies · $3.8B](https://millionrounds.com/top-lists/healthcare-startups-founded-2020)[*AH* *CR* *V* **Healthcare startups founded in 2019** 380 companies · $11B](https://millionrounds.com/top-lists/healthcare-startups-founded-2019)[*IL* *E* *O* **Healthcare startups founded in 2021** 304 companies · $10B](https://millionrounds.com/top-lists/healthcare-startups-founded-2021)

## More lists for Cleveland

[See all](https://millionrounds.com/top-lists?r=Cleveland)

[*F* *E* *ST* **Startups in Cleveland** 81 companies · $1.6B](https://millionrounds.com/top-lists/startups-cleveland)[*ST* *JT* *CS* **Biotech startups in Cleveland** 14 companies · $225M](https://millionrounds.com/top-lists/biotech-startups-cleveland)