# Top 50 Health Startups in Chicago by Funding (2026)

> The 50 best-funded health startups in Chicago, ranked by total funding raised: $9.6B combined. With founding year, headquarters and each company's rounds.

Source: https://millionrounds.com/top-lists/health-startups-chicago (Millionrounds; every figure on the page links to its filing or article)

- 1 [**VillageMD** VillageMD is a national primary care platform based in Chicago, Illinois, founded in 2013.](https://millionrounds.com/company/villagemd) VillageMD is a national primary care platform based in Chicago, Illinois, founded in 2013. *Founded* 2013 Chicago, United States **$6.9B** last round Jan 2023
- 2 [**Outcome Health** Outcome Health is a prominent healthcare technology company based in Chicago, Illinois, focused on enhancing patient care through innovative digital solutions.](https://millionrounds.com/company/outcome-health) Outcome Health is a prominent healthcare technology company based in Chicago, Illinois, focused on enhancing patient care through innovative digital solutions. *Founded* 2006 Chicago, United States **$600M** last round May 2017
- 3 [**Nature's Fynd** Nature's Fynd is a Chicago-based food-tech company that specializes in creating animal-free meat and dairy alternatives.](https://millionrounds.com/company/nature-s-fynd) Nature's Fynd is a Chicago-based food-tech company that specializes in creating animal-free meat and dairy alternatives. *Founded* 2012 Chicago, United States **$350M** last round Jul 2021
- 4 [**Oak Street Health** Oak Street Health is a network of primary care centers for adults on Medicare.](https://millionrounds.com/company/oak-street-health) Oak Street Health is a network of primary care centers for adults on Medicare. *Founded* 2012 Chicago, United States **$340M** last round Nov 2022
- 5 [**Emalex Biosciences** Emalex Biosciences is a biotech startup that develops new treatments for central nervous system disorders.](https://millionrounds.com/company/emalex-biosciences) Emalex Biosciences is a biotech startup that develops new treatments for central nervous system disorders. *Founded* 2018 Chicago, United States **$270M** last round Nov 2022
- 6 [**Zing Health** Zing Health offers Medicare advantage plans that enhances healthcare access and include supplemental benefits.](https://millionrounds.com/company/zing-health) Zing Health offers Medicare advantage plans that enhances healthcare access and include supplemental benefits. *Founded* 2019 Chicago, United States **$140M** last round Sept 2024
- 7 [**Vanqua Bio** Vanqua Bio is a biopharmaceutical company based in Chicago, founded in 2019.](https://millionrounds.com/company/vanqua-bio) Vanqua Bio is a biopharmaceutical company based in Chicago, founded in 2019. *Founded* 2019 Chicago, United States **$130M** last round Jul 2024
- 8 [**HealthJoy** HealthJoy is a healthcare technology company based in Chicago, founded in 2014.](https://millionrounds.com/company/healthjoy) HealthJoy is a healthcare technology company based in Chicago, founded in 2014. *Founded* 2014 Chicago, United States **$73M** last round Oct 2022
- 9 [**NeuroTherapeutics Pharma** NeuroTherapeutics Pharma is a biopharmaceutical company developing new therapies to treat pain, epilepsy, and other nervous system disorder.](https://millionrounds.com/company/neurotherapeutics-pharma) NeuroTherapeutics Pharma is a biopharmaceutical company developing new therapies to treat pain, epilepsy, and other nervous system disorder. *Founded* 2006 Chicago, United States **$58M** last round Dec 2011
- 10 [**DxTx Pain and Spine** DxTx Pain and Spine is a healthcare practice management firm that operates a network of around 60 interventional pain and spine practices and ambulatory surgery](https://millionrounds.com/company/dxtx-pain-and-spine) DxTx Pain and Spine is a healthcare practice management firm that operates a network of around 60 interventional pain and spine practices and ambulatory surgery *Founded* 2019 Chicago, United States **$50M** last round Jul 2023
- 11 [**Evive** Evive seamlessly integrates benefits into the lives of more than 4 million people every day.](https://millionrounds.com/company/evive) Evive seamlessly integrates benefits into the lives of more than 4 million people every day. *Founded* 2007 Chicago, United States **$47M** last round Jun 2020
- 12 [**Artisight** Artisight is a healthcare technology company based in Chicago, Illinois, founded in 2017 by clinician Andrew Gostine and technology executive Garrett Larance.](https://millionrounds.com/company/artisight) Artisight is a healthcare technology company based in Chicago, Illinois, founded in 2017 by clinician Andrew Gostine and technology executive Garrett Larance. *Founded* 2017 Chicago, United States **$42M** last round Jan 2024
- 13 [**Meitheal Pharmaceuticals** Meitheal Pharmaceuticals specializes in research, manufacturing, and supply of injection medicine.](https://millionrounds.com/company/meitheal-pharmaceuticals) Meitheal Pharmaceuticals specializes in research, manufacturing, and supply of injection medicine. *Founded* 2017 Chicago, United States **$35M** last round Aug 2023
- 14 [**Kalderos** Kalderos provides a SaaS based drug discount management solution, which identifies, checks, and resolves non-compliance.](https://millionrounds.com/company/kalderos) Kalderos provides a SaaS based drug discount management solution, which identifies, checks, and resolves non-compliance. *Founded* 2016 Chicago, United States **$33M** last round Jan 2025
- 15 [**Cylinder** Cylinder is a digital health company that offers personalized care for people with digestive conditions.](https://millionrounds.com/company/cylinder) Cylinder is a digital health company that offers personalized care for people with digestive conditions. *Founded* 2021 Chicago, United States **$31M** last round Sept 2023
- 16 [**Novian Health** Novian Health is a medical device company transforming healthcare through innovation such as Novilase laser ablation for breast tumors.](https://millionrounds.com/company/novian-health) Novian Health is a medical device company transforming healthcare through innovation such as Novilase laser ablation for breast tumors. *Founded* 1991 Chicago, United States **$30M** last round Mar 2026
- 17 [**Emmaus** EMMAUS is an NGO that fights to end trafficking, prevent exploitation and empower male survivors of the sex trade to rebuild their lives.](https://millionrounds.com/company/emmaus) EMMAUS is an NGO that fights to end trafficking, prevent exploitation and empower male survivors of the sex trade to rebuild their lives. *Founded* 1990 Chicago, United States **$30M** last round Jan 2018
- 18 [**MAIA Biotechnology** MAIA Biotechnology is a clinical-stage biopharmaceutical company developing cancer therapies that target telomeres through immunotherapy.](https://millionrounds.com/company/maia-biotechnology) MAIA Biotechnology is a clinical-stage biopharmaceutical company developing cancer therapies that target telomeres through immunotherapy. *Founded* 2018 Chicago, United States **$30M** last round Mar 2026
- 19 [**PatientIQ** PatientIQ is a healthcare technology company based in Chicago, founded in 2016.](https://millionrounds.com/company/patientiq) PatientIQ is a healthcare technology company based in Chicago, founded in 2016. *Founded* 2016 Chicago, United States **$30M** last round Sept 2026
- 20 [**Atraverse Medical** Atraverse Medical offers a product development for left-heart access technology to simplify workflows and improve patient outcomes.](https://millionrounds.com/company/atraverse-medical) Atraverse Medical offers a product development for left-heart access technology to simplify workflows and improve patient outcomes. *Founded* 2022 Chicago, United States **$29M** last round Jun 2025
- 21 [**KeyCare** KeyCare is a virtual care platform that enhances telehealth solutions for health systems using Epic's infrastructure.](https://millionrounds.com/company/keycare) KeyCare is a virtual care platform that enhances telehealth solutions for health systems using Epic's infrastructure. *Founded* 2022 Chicago, United States **$29M** last round Sept 2026
- 22 [**Cardiosense** Cardiosense is a Chicago-based digital health company focused on precision cardiac care through AI-enabled solutions.](https://millionrounds.com/company/cardiosense) Cardiosense is a Chicago-based digital health company focused on precision cardiac care through AI-enabled solutions. *Founded* 2020 Chicago, United States **$26M** last round Aug 2026
- 23 [**Synapticure** Synapticure is a virtual clinical care company founded in 2019 and based in Chicago, IL.](https://millionrounds.com/company/synapticure) Synapticure is a virtual clinical care company founded in 2019 and based in Chicago, IL. *Founded* 2019 Chicago, United States **$25M** last round Nov 2024
- 24 [**higi** Higi's platform enables & empowers users to self-screen their biometrics & share that data with a trusted health professional.](https://millionrounds.com/company/higi) Higi's platform enables & empowers users to self-screen their biometrics & share that data with a trusted health professional. *Founded* 2012 Chicago, United States **$21M** last round Jul 2018
- 25 [**Caremerge** Caremerge is a provider of Senior Living Electronic Health Record (EHR) and Resident Engagement Solutions, aimed at enhancing the experience for Assisted Living](https://millionrounds.com/company/caremerge) Caremerge is a provider of Senior Living Electronic Health Record (EHR) and Resident Engagement Solutions, aimed at enhancing the experience for Assisted Living *Founded* 2012 Chicago, United States **$20M** last round Jul 2016
- 26 [**Homethrive** Homethrive is a technology-enabled healthcare service company founded in 2018, headquartered in Northbrook, Illinois.](https://millionrounds.com/company/homethrive) Homethrive is a technology-enabled healthcare service company founded in 2018, headquartered in Northbrook, Illinois. *Founded* 2018 Chicago, United States **$20M** last round Nov 2024
- 27 [**Praia Health** Praia Health is a digital health growth platform focused on enhancing patient experiences for health systems.](https://millionrounds.com/company/praia-health) Praia Health is a digital health growth platform focused on enhancing patient experiences for health systems. *Founded* 2024 Chicago, United States **$20M** last round Nov 2024
- 28 [**Surgical Innovation Associates** Surgical Innovation Associates is a developer of implantable polymeric surgical devices for plastic, reconstructive, and general surgery.](https://millionrounds.com/company/surgical-innovation-associates) Surgical Innovation Associates is a developer of implantable polymeric surgical devices for plastic, reconstructive, and general surgery. *Founded* 2016 Chicago, United States **$19M** last round Dec 2021
- 29 [**IMIO** IMIO's natural, microbe-based fertilizers outperform chemicals, increasing yields and improving soil health for regenerative agriculture.](https://millionrounds.com/company/imio) IMIO's natural, microbe-based fertilizers outperform chemicals, increasing yields and improving soil health for regenerative agriculture. *Founded* - Chicago, United States **$19M** last round Oct 2026
- 30 [**SyntaxBio** Syntax Bio is a Chicago-based synthetic biology and biotechnology company that specializes in programming stem cells to enhance the development and manufacturin](https://millionrounds.com/company/syntax-bio) Syntax Bio is a Chicago-based synthetic biology and biotechnology company that specializes in programming stem cells to enhance the development and manufacturin *Founded* 2021 Chicago, United States **$15M** last round Jul 2026
- 31 [**SimBioSys** SimBioSys is developing a Computational Microscope to provide new insight into the behavior of cancers.](https://millionrounds.com/company/simbiosys) SimBioSys is developing a Computational Microscope to provide new insight into the behavior of cancers. *Founded* 2016 Chicago, United States **$15M** last round Oct 2021
- 32 [**SonarMD** SonarMD provides care management for chronic conditions that use drugs.](https://millionrounds.com/company/sonarmd) SonarMD provides care management for chronic conditions that use drugs. *Founded* 2015 Chicago, United States **$13M** last round Mar 2026
- 33 [**Amphix Bio** Amphix Bio is a biotechnology company that develops regenerative medicine therapies using a platform of supramolecular therapeutic peptides.](https://millionrounds.com/company/amphix-bio) Amphix Bio is a biotechnology company that develops regenerative medicine therapies using a platform of supramolecular therapeutic peptides. *Founded* - Chicago, United States **$13M** last round Dec 2025
- 34 [**Stately Bio** Stately Bio is a biotechnology company based in Palo Alto, founded in 2022.](https://millionrounds.com/company/stately-bio) Stately Bio is a biotechnology company based in Palo Alto, founded in 2022. *Founded* - Chicago, United States **$12M** last round May 2025
- 35 [**PinpointCare** PinpointCare is a healthcare software company based in Chicago that offers a cloud-based SaaS platform for coordinating patient care.](https://millionrounds.com/company/pinpointcare) PinpointCare is a healthcare software company based in Chicago that offers a cloud-based SaaS platform for coordinating patient care. *Founded* 2009 Chicago, United States **$11M** last round Sept 2015
- 36 [**Senior Lifestyle** Senior Lifestyle is a family-owned senior living specialist based in Chicago, Illinois, founded in 1985 by Bill Kaplan.](https://millionrounds.com/company/senior-lifestyle) Senior Lifestyle is a family-owned senior living specialist based in Chicago, Illinois, founded in 1985 by Bill Kaplan. *Founded* 1985 Chicago, United States **$10M** last round Dec 2014
- 37 [**Attune Medical** Now part of Haemonetics!](https://millionrounds.com/company/attune-medical) Now part of Haemonetics! *Founded* 2009 Chicago, United States **$10M** last round Oct 2017
- 38 [**Healthbox** Healthbox is a healthcare advisory firm that helps an organization develop their strategies and programs.](https://millionrounds.com/company/healthbox) Healthbox is a healthcare advisory firm that helps an organization develop their strategies and programs. *Founded* 2010 Chicago, United States **$9.0M** last round Apr 2014
- 39 [**BiomeSense** BiomeSense is a life sciences and biotechnology startup based in Chicago, Illinois, founded in 2018.](https://millionrounds.com/company/biomesense) BiomeSense is a life sciences and biotechnology startup based in Chicago, Illinois, founded in 2018. *Founded* 2018 Chicago, United States **$8.2M** last round Aug 2025
- 40 [**First Stop Health** First Stop Health is a virtual-first healthcare company that offers connected telemedicine and mental health care services to employers, employees, and their fa](https://millionrounds.com/company/first-stop-health) First Stop Health is a virtual-first healthcare company that offers connected telemedicine and mental health care services to employers, employees, and their fa *Founded* 2011 Chicago, United States **$8.1M** last round Jan 2019
- 41 [**Auxira Health** Auxira Health is a telehealth staffing and virtual care company that specializes in cardiology.](https://millionrounds.com/company/auxira-health) Auxira Health is a telehealth staffing and virtual care company that specializes in cardiology. *Founded* - Chicago, United States **$7.8M** last round Dec 2025
- 42 [**Third Eye Health** Third Eye Health is a leading virtual care provider based in Chicago, IL, specializing in post-acute and long-term care since its founding in 2014.](https://millionrounds.com/company/third-eye-health) Third Eye Health is a leading virtual care provider based in Chicago, IL, specializing in post-acute and long-term care since its founding in 2014. *Founded* 2014 Chicago, United States **$6.0M** last round Sept 2023
- 43 [**Sword Diagnostics** Sword Diagnostics is a life sciences company addressing the needs of the research, pharmaceutical, and clinical communities.](https://millionrounds.com/company/sword-diagnostics) Sword Diagnostics is a life sciences company addressing the needs of the research, pharmaceutical, and clinical communities. *Founded* 2004 Chicago, United States **$5.5M** last round May 2015
- 44 [**Dentologie** Dentologie is a dental clinic that offers services like general dentistry, Invisalign, oral surgeries, and cosmetic dentistry.](https://millionrounds.com/company/dentologie) Dentologie is a dental clinic that offers services like general dentistry, Invisalign, oral surgeries, and cosmetic dentistry. *Founded* 2012 Chicago, United States **$5.2M** last round Dec 2024
- 45 [**WellRight** WellRight is a provider of cloud-based corporate wellness software, catering to mid-sized and large enterprises.](https://millionrounds.com/company/wellright) WellRight is a provider of cloud-based corporate wellness software, catering to mid-sized and large enterprises. *Founded* 2013 Chicago, United States **$4.6M** last round Oct 2014
- 46 [**Maia Oncology** Maia Oncology is an onco-primary care clinic for cancer patients and survivors.](https://millionrounds.com/company/maia-oncology) Maia Oncology is an onco-primary care clinic for cancer patients and survivors. *Founded* 2023 Chicago, United States **$4.3M** last round Nov 2023
- 47 [**Tonic Health** Tonic was founded by a collaboration of scientists, consumer marketing experts, user interface designers and software programmers to](https://millionrounds.com/company/tonic-health) Tonic was founded by a collaboration of scientists, consumer marketing experts, user interface designers and software programmers to *Founded* 2010 Chicago, United States **$4.1M** last round Jul 2025
- 48 [**OrisDX** OrisDX is a biotechnology company based in Chicago, Illinois, focused on early disease detection through innovative salivary diagnostics.](https://millionrounds.com/company/orisdx) OrisDX is a biotechnology company based in Chicago, Illinois, focused on early disease detection through innovative salivary diagnostics. *Founded* 2021 Chicago, United States **$4.0M** last round Jun 2025
- 49 [**EDGe Surgical** EDGe Surgical is a medical device company that offers innovative precision measurement solutions for orthopedic surgery.](https://millionrounds.com/company/edge-surgical) EDGe Surgical is a medical device company that offers innovative precision measurement solutions for orthopedic surgery. *Founded* 2015 Chicago, United States **$4.0M** last round Dec 2018
- 50 [**Novascan** NovaScan is a clinical-stage oncology company based in Chicago, Illinois, focused on AI-enhanced, low-cost point-of-care technology for real-time cancer detecti](https://millionrounds.com/company/novascan) NovaScan is a clinical-stage oncology company based in Chicago, Illinois, focused on AI-enhanced, low-cost point-of-care technology for real-time cancer detecti *Founded* 2003 Chicago, United States **$3.8M** last round Aug 2026

**Total funding** how the list is ranked

**15 November 2026** updated nightly

**Rounds we track** source: Millionrounds

Companies whose funding rounds we classed as any of these sectors, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.

## Who backed them?

Open any company for its rounds and investors, or search the investors who back health startups in Chicago in the app, with filters, lists and exports.

[Find their investors](https://millionrounds.com/login?join=1&next=/app/investors)[All top lists](https://millionrounds.com/top-lists)

## More health lists

[See all](https://millionrounds.com/top-lists?t=Health)

[*GV* *V* *RP* **Health startups worldwide** 12,811 companies · $81B](https://millionrounds.com/top-lists/health-startups)[*GV* *V* *RP* **Health startups in the United States** 7,411 companies · $71B](https://millionrounds.com/top-lists/health-startups-united-states)[*IL* *O* *NH* **Health startups in Europe** 3,025 companies · $29B](https://millionrounds.com/top-lists/health-startups-europe)[*IL* *CS* *ON* **Health startups in the United Kingdom** 1,094 companies · $17B](https://millionrounds.com/top-lists/health-startups-united-kingdom)[*AL* *RM* *F* **Health startups in Bay Area** 959 companies · $33B](https://millionrounds.com/top-lists/health-startups-bay-area)[*DH* *BM* *W* **Health startups in Boston** 617 companies · $27B](https://millionrounds.com/top-lists/health-startups-boston)[*NH* *OH* *R* **Health startups in New York** 406 companies · $14B](https://millionrounds.com/top-lists/health-startups-new-york)[*A* *T* *AP* **Health startups in Canada** 386 companies · $5.7B](https://millionrounds.com/top-lists/health-startups-canada)

## More lists for Chicago

[See all](https://millionrounds.com/top-lists?r=Chicago)

[*V* *OH* *O* **Startups in Chicago** 617 companies · $16B](https://millionrounds.com/top-lists/startups-chicago)[*V* *OH* *OS* **Healthcare startups in Chicago** 62 companies · $8.7B](https://millionrounds.com/top-lists/healthcare-startups-chicago)[*N* *R* *S* **IT Services startups in Chicago** 48 companies · $948M](https://millionrounds.com/top-lists/it-services-startups-chicago)[*O* *C* *E* **AI startups in Chicago** 45 companies · $912M](https://millionrounds.com/top-lists/ai-startups-chicago)[*V* *OH* *NF* **Biotech startups in Chicago** 34 companies · $8.5B](https://millionrounds.com/top-lists/biotech-startups-chicago)[*O* *P* *CA* **Big Data & Analytics startups in Chicago** 32 companies · $771M](https://millionrounds.com/top-lists/big-data-startups-chicago)[*D* *T* *LO* **Advertising & Adtech startups in Chicago** 30 companies · $320M](https://millionrounds.com/top-lists/adtech-startups-chicago)[*SA* *A* *S* **Software startups in Chicago** 28 companies · $845M](https://millionrounds.com/top-lists/software-startups-chicago)