# Top 50 Chronic Disease Startups Worldwide by Funding (2026)

> The 50 best-funded chronic disease startups worldwide, ranked by total funding raised: $7.3B combined.

Source: https://millionrounds.com/top-lists/chronic-disease-startups (Millionrounds; every figure on the page links to its filing or article)

- 1 [**Intarcia Therapeutics** Intarcia Therapeutics develops therapies for diseases that require long-term chronic treatment.](https://millionrounds.com/company/intarcia-therapeutics) Intarcia Therapeutics develops therapies for diseases that require long-term chronic treatment. *Founded* 1997 Boston, United States **$1.1B** last round Sept 2016
- 2 [**Oruka Therapeutics** Oruka Therapeutics is advancing innovative biologics to redefine patient care standards in chronic skin diseases.](https://millionrounds.com/company/oruka-therapeutics) Oruka Therapeutics is advancing innovative biologics to redefine patient care standards in chronic skin diseases. *Founded* - Waltham, United States **$880M** last round Apr 2026
- 3 [**Strive Health** Strive Health is a healthcare technology company based in Denver, Colorado, focused on value-based kidney care.](https://millionrounds.com/company/strive-health) Strive Health is a healthcare technology company based in Denver, Colorado, focused on value-based kidney care. *Founded* 2018 Denver, United States **$440M** last round Sept 2025
- 4 [**Tubulis** Tubulis is a chemotherapeutic medication developer specializing in cancer and chronic disease treatment.](https://millionrounds.com/company/tubulis) Tubulis is a chemotherapeutic medication developer specializing in cancer and chronic disease treatment. *Founded* 2012 Munich, Germany **$401M** last round Oct 2025
- 5 [**Dice Therapeutics** Dice Therapeutics is a clinical-stage biopharmaceutical company that makes medicines for chronic autoimmune and inflammatory diseases.](https://millionrounds.com/company/dice-therapeutics) Dice Therapeutics is a clinical-stage biopharmaceutical company that makes medicines for chronic autoimmune and inflammatory diseases. *Founded* 2013 San Francisco, United States **$345M** last round Oct 2022
- 6 [**Liberty Dialysis** Liberty Dialysis affiliates, develops and operates dialysis clinics and offers chronic kidney disease outreach and home dialysis programs.](https://millionrounds.com/company/liberty-dialysis) Liberty Dialysis affiliates, develops and operates dialysis clinics and offers chronic kidney disease outreach and home dialysis programs. *Founded* 2002 Mercer Island, United States **$340M** last round Jul 2010
- 7 [**Morphic Therapeutic** Morphic Therapeutic is a biotechnology company that develops oral integrin therapies to treat serious chronic diseases.](https://millionrounds.com/company/morphic-therapeutic) Morphic Therapeutic is a biotechnology company that develops oral integrin therapies to treat serious chronic diseases. *Founded* 2015 Waltham, United States **$328M** last round May 2023
- 8 [**Expedition Therapeutics** Expedition Therapeutics is a biotechnology company based in San Francisco, founded in 2024.](https://millionrounds.com/company/expedition-therapeutics) Expedition Therapeutics is a biotechnology company based in San Francisco, founded in 2024. *Founded* 2024 San Francisco, United States **$280M** last round Aug 2026
- 9 [**Samay** Samay Health, founded in 2018 by Dr.](https://millionrounds.com/company/samay) Samay Health, founded in 2018 by Dr. *Founded* 2019 Mountain View, United States **$250M** last round May 2026
- 10 [**Aviceda Therapeutics** Aviceda Therapeutics is a clinical-stage biotechnology company based in Cambridge, Massachusetts, founded in 2018.](https://millionrounds.com/company/aviceda-therapeutics) Aviceda Therapeutics is a clinical-stage biotechnology company based in Cambridge, Massachusetts, founded in 2018. *Founded* 2018 Cambridge, United States **$208M** last round Jan 2025
- 11 [**AirNexis Therapeutics** AirNexis Therapeutics develops clinical-stage therapies for chronic obstructive pulmonary disease and other pulmonary conditions.](https://millionrounds.com/company/airnexis-therapeutics) AirNexis Therapeutics develops clinical-stage therapies for chronic obstructive pulmonary disease and other pulmonary conditions. *Founded* - Palo Alto, United States **$200M** last round Jan 2026
- 12 [**Resolution Therapeutics** Resolution Therapeutics is a biopharmaceutical company developing macrophage cell therapy to treat chronic diseases.](https://millionrounds.com/company/resolution-therapeutics) Resolution Therapeutics is a biopharmaceutical company developing macrophage cell therapy to treat chronic diseases. *Founded* 2017 London, United Kingdom **$159M** last round May 2026
- 13 [**Cala Health** Cala Health is a bioelectronic medicine company based in San Mateo, California, founded in 2013.](https://millionrounds.com/company/cala-health) Cala Health is a bioelectronic medicine company based in San Mateo, California, founded in 2013. *Founded* 2014 San Mateo, United States **$150M** last round Apr 2026
- 14 [**Prokidney** Prokidney provide specialized treatment for chronic kidney disease.](https://millionrounds.com/company/prokidney) Prokidney provide specialized treatment for chronic kidney disease. *Founded* - Salem, United States **$140M** last round Jun 2024
- 15 [**Apreo Health** Apreo Health is a clinical-stage medical device company based in Menlo Park, California, founded in 2021.](https://millionrounds.com/company/apreo-health) Apreo Health is a clinical-stage medical device company based in Menlo Park, California, founded in 2021. *Founded* - Menlo Park, United States **$130M** last round May 2026
- 16 [**Galvanize** Galvanize Therapeutics is a commercial-stage medical technology company based in San Carlos, California.](https://millionrounds.com/company/galvanize) Galvanize Therapeutics is a commercial-stage medical technology company based in San Carlos, California. *Founded* 2015 Redwood City, United States **$125M** last round Jan 2019
- 17 [**Ouro Medicines** Ouro Medicines is a biotechnology company based in South San Francisco, established in 2025 by Monograph Capital in partnership with GSK.](https://millionrounds.com/company/ouro-medicines) Ouro Medicines is a biotechnology company based in South San Francisco, established in 2025 by Monograph Capital in partnership with GSK. *Founded* 2024 San Francisco, United States **$120M** last round Jan 2025
- 18 [**Pathalys Pharma** Pathalys Pharma is a private biopharmaceutical company based in Raleigh, North Carolina, founded in 2021.](https://millionrounds.com/company/pathalys-pharma) Pathalys Pharma is a private biopharmaceutical company based in Raleigh, North Carolina, founded in 2021. *Founded* 2021 Raleigh, United States **$105M** last round Aug 2024
- 19 [**Virtue Diagnostics** Virtue Diagnostics is a global in vitro diagnostics (IVD) company founded in 2019, with a focus on providing affordable and precise clinical solutions for infec](https://millionrounds.com/company/virtue-diagnostics) Virtue Diagnostics is a global in vitro diagnostics (IVD) company founded in 2019, with a focus on providing affordable and precise clinical solutions for infec *Founded* 2019 Singapore, Singapore **$100M** last round Jan 2022
- 20 [**Mironid** Mironid is a drug discovery company focused on therapeutics for degenerative kidney diseases, chronic inflammatory diseases, and cancer.](https://millionrounds.com/company/mironid) Mironid is a drug discovery company focused on therapeutics for degenerative kidney diseases, chronic inflammatory diseases, and cancer. *Founded* 2014 Glasgow, United Kingdom **$99M** last round Aug 2026
- 21 [**Calluna Pharma** Calluna Pharma is a clinical-stage biotechnology company based in Oslo, Norway.](https://millionrounds.com/company/calluna-pharma) Calluna Pharma is a clinical-stage biotechnology company based in Oslo, Norway. *Founded* 2024 Oslo, Norway **$81M** last round Jan 2024
- 22 [**Viome** Viome is a systems biology company founded in 2016, dedicated to analyzing individual biology at a molecular level.](https://millionrounds.com/company/viome) Viome is a systems biology company founded in 2016, dedicated to analyzing individual biology at a molecular level. *Founded* 2016 Bellevue, United States **$71M** last round Sept 2024
- 23 [**Propeller Health** Propeller Health, now operating as Reciprocal Labs Corporation under ResMed, was a digital therapeutics company founded in 2010.](https://millionrounds.com/company/propeller-health) Propeller Health, now operating as Reciprocal Labs Corporation under ResMed, was a digital therapeutics company founded in 2010. *Founded* 2010 San Diego, United States **$70M** last round May 2018
- 24 [**Cagent Vascular** Cagent Vascular is a medical device company based in Wayne, Pennsylvania, focused on advancing treatment for Peripheral Artery Disease (PAD) and Chronic Limb-Th](https://millionrounds.com/company/cagent-vascular) Cagent Vascular is a medical device company based in Wayne, Pennsylvania, focused on advancing treatment for Peripheral Artery Disease (PAD) and Chronic Limb-Th *Founded* 2014 Wayne, United States **$68M** last round May 2026
- 25 [**Inotrem** Inotrem is a French biotechnology company founded in 2013, based in Paris with a technology center in Nancy.](https://millionrounds.com/company/inotrem) Inotrem is a French biotechnology company founded in 2013, based in Paris with a technology center in Nancy. *Founded* 2013 Paris, France **$66M** last round Nov 2023
- 26 [**Imcyse** Developing disease specific immune therapies to treat severe, chronic auto-immune, inflammatory, allergic, infectious diseases and tumors.](https://millionrounds.com/company/imcyse) Developing disease specific immune therapies to treat severe, chronic auto-immune, inflammatory, allergic, infectious diseases and tumors. *Founded* 2010 Liege, Belgium **$65M** last round Feb 2021
- 27 [**Gold Kidney Health Plan** Gold Kidney Health Plan is a Medicare Advantage organization that specializes in Chronic Special Needs Plans (C-SNPs) for individuals with end-stage renal disea](https://millionrounds.com/company/gold-kidney-health-plan) Gold Kidney Health Plan is a Medicare Advantage organization that specializes in Chronic Special Needs Plans (C-SNPs) for individuals with end-stage renal disea *Founded* 2021 Portsmouth, United States **$60M** last round Dec 2022
- 28 [**Twin Health** Twin Health is a HealthTech company founded in 2018 and based in Mountain View, California, with operations in Chennai, India.](https://millionrounds.com/company/twin-health) Twin Health is a HealthTech company founded in 2018 and based in Mountain View, California, with operations in Chennai, India. *Founded* 2018 Menlo Park, United States **$59M** last round Sept 2026
- 29 [**Medopad** Medopad, now known as Huma, is a global health technology company founded in 2011 and based in London, with additional offices in the US and China.](https://millionrounds.com/company/medopad) Medopad, now known as Huma, is a global health technology company founded in 2011 and based in London, with additional offices in the US and China. *Founded* 2011 London, United Kingdom **$54M** last round Nov 2019
- 30 [**Endpoint Health** Endpoint Health is a precision-medicine therapeutics company based in Palo Alto, California, founded in 2018.](https://millionrounds.com/company/endpoint-health) Endpoint Health is a precision-medicine therapeutics company based in Palo Alto, California, founded in 2018. *Founded* 2018 Palo Alto, United States **$52M** last round Jun 2022
- 31 [**Montai Therapeutics** Montai Therapeutics is a biotechnology company based in Cambridge, MA, founded in 2022.](https://millionrounds.com/company/montai-therapeutics) Montai Therapeutics is a biotechnology company based in Cambridge, MA, founded in 2022. *Founded* 2022 Cambridge, United States **$50M** last round Dec 2022
- 32 [**HealthSnap** HealthSnap is a virtual care management platform for chronic disease management.](https://millionrounds.com/company/healthsnap) HealthSnap is a virtual care management platform for chronic disease management. *Founded* 2015 Miami, United States **$50M** last round Aug 2026
- 33 [**Novome Biotechnologies** Novome Biotechnologies is a clinical-stage biotechnology company located in South San Francisco, California.](https://millionrounds.com/company/novome-biotechnologies) Novome Biotechnologies is a clinical-stage biotechnology company located in South San Francisco, California. *Founded* 2016 South San Francisco, United States **$44M** last round Sept 2022
- 34 [**Arda Therapeutics** Arda Therapeutics is a biotechnology company based in the San Francisco Bay Area, founded in 2021.](https://millionrounds.com/company/arda-therapeutics) Arda Therapeutics is a biotechnology company based in the San Francisco Bay Area, founded in 2021. *Founded* 2021 San Carlos, United States **$43M** last round Oct 2024
- 35 [**Symic Bio** Symic Bio is a biopharmaceutical company based in San Francisco, California, founded in 2012.](https://millionrounds.com/company/symic-bio) Symic Bio is a biopharmaceutical company based in San Francisco, California, founded in 2012. *Founded* 2012 San Francisco, United States **$41M** last round Apr 2019
- 36 [**Juventas Therapeutics** Juventas is a biotechnology company that discovers and develops non-viral gene therapies for the treatment of chronic cardiovascular diseases.](https://millionrounds.com/company/juventas-therapeutics) Juventas is a biotechnology company that discovers and develops non-viral gene therapies for the treatment of chronic cardiovascular diseases. *Founded* 2007 Cleveland, United States **$41M** last round May 2015
- 37 [**Curve Biosciences** Curve Biosciences is a biotechnology company based in San Mateo, California, founded in 2021.](https://millionrounds.com/company/curve-biosciences) Curve Biosciences is a biotechnology company based in San Mateo, California, founded in 2021. *Founded* 2021 Dallas, United States **$40M** last round Oct 2025
- 38 [**Holmusk** Holmusk is a provider of healthcare data and technology solutions to support the treatment of mental health and chronic diseases.](https://millionrounds.com/company/holmusk) Holmusk is a provider of healthcare data and technology solutions to support the treatment of mental health and chronic diseases. *Founded* 2015 Singapore, Singapore **$40M** last round Oct 2023
- 39 [**HealthReveal** HealthReveal provides a cloud-based clinical analytics platform designed to preempt the avoidable consequences of chronic disease.](https://millionrounds.com/company/healthreveal) HealthReveal provides a cloud-based clinical analytics platform designed to preempt the avoidable consequences of chronic disease. *Founded* 2015 New York, United States **$37M** last round Dec 2019
- 40 [**Scioderm** Scioderm, a clinical stage pharmaceutical company, develops topical products for the treatment of chronic skin diseases.](https://millionrounds.com/company/scioderm) Scioderm, a clinical stage pharmaceutical company, develops topical products for the treatment of chronic skin diseases. *Founded* 2012 Durham, United States **$37M** last round Dec 2014
- 41 [**Virta Health** Virta Health is a technology-enabled telehealth company focused on reversing chronic metabolic diseases, particularly Type 2 diabetes and obesity, without medic](https://millionrounds.com/company/virta-health) Virta Health is a technology-enabled telehealth company focused on reversing chronic metabolic diseases, particularly Type 2 diabetes and obesity, without medic *Founded* 2014 Denver, United States **$37M** last round Mar 2017
- 42 [**mbiomics GmbH** mbiomics GmbH is a biotechnology company based in Munich, Germany, founded in 2020 by Laura Figulla, Markus Rinecker, and Johannes Wöhrstein.](https://millionrounds.com/company/mbiomics-gmbh) mbiomics GmbH is a biotechnology company based in Munich, Germany, founded in 2020 by Laura Figulla, Markus Rinecker, and Johannes Wöhrstein. *Founded* 2020 Neuried, Germany **$35M** last round May 2026
- 43 [**HepaRegeniX** HepaRegeniX is developing drugs for treating acute and chronic liver diseases.](https://millionrounds.com/company/heparegenix) HepaRegeniX is developing drugs for treating acute and chronic liver diseases. *Founded* 2015 Tuebingen, Germany **$34M** last round Apr 2025
- 44 [**Longeveron** Longeveron is a biotechnology company that focuses on developing cellular therapies for chronic aging-related and life-threatening diseases.](https://millionrounds.com/company/longeveron) Longeveron is a biotechnology company that focuses on developing cellular therapies for chronic aging-related and life-threatening diseases. *Founded* 2014 Miami, United States **$30M** last round Mar 2026
- 45 [**Ochre Bio** Ochre Bio is a biotechnology company based in Oxford, United Kingdom, founded in 2019.](https://millionrounds.com/company/ochre-bio) Ochre Bio is a biotechnology company based in Oxford, United Kingdom, founded in 2019. *Founded* 2019 Oxford, United Kingdom **$30M** last round Oct 2022
- 46 [**Alcresta** Alcresta develops enzyme-based nutritional products for infants and adults with acute and chronic diseases.](https://millionrounds.com/company/alcresta) Alcresta develops enzyme-based nutritional products for infants and adults with acute and chronic diseases. *Founded* 2011 Newton, United States **$30M** last round Feb 2020
- 47 [**Istesso** Istesso is a London-based biopharmaceutical company focused on immunometabolism drug discovery and development.](https://millionrounds.com/company/istesso) Istesso is a London-based biopharmaceutical company focused on immunometabolism drug discovery and development. *Founded* 2017 London, United Kingdom **$29M** last round Apr 2023
- 48 [**AbolerIS Pharma** AbolerIS Pharma is a Belgian clinical-stage biopharmaceutical company founded in November 2019.](https://millionrounds.com/company/aboleris-pharma) AbolerIS Pharma is a Belgian clinical-stage biopharmaceutical company founded in November 2019. *Founded* 2019 Charleroi, France **$29M** last round Sept 2023
- 49 [**Spyglass Ophthalmics** SpyGlass is a California-based ophthalmic therapeutics company that researches and develops novel treatments for chronic ophthalmic diseases.](https://millionrounds.com/company/spyglass-ophthalmics) SpyGlass is a California-based ophthalmic therapeutics company that researches and develops novel treatments for chronic ophthalmic diseases. *Founded* 2019 Mission Viejo, United States **$28M** last round Jan 2021
- 50 [**Wellinks** Wellinks is a digital health company based in New Haven, Connecticut, focused on enhancing cardiopulmonary care, particularly for individuals with Chronic Obstr](https://millionrounds.com/company/wellinks) Wellinks is a digital health company based in New Haven, Connecticut, focused on enhancing cardiopulmonary care, particularly for individuals with Chronic Obstr *Founded* 2014 New Haven, United States **$25M** last round Nov 2021

**Total funding** how the list is ranked

**15 November 2026** updated nightly

**Rounds we track** source: Millionrounds

Companies whose own description names this theme, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.

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## More lists worldwide

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