# Top 50 Biotech Startups in South San Francisco by Funding (2026) > The 50 best-funded biotech startups in South San Francisco, ranked by total funding raised: $12B combined. Source: https://millionrounds.com/top-lists/biotech-startups-south-san-francisco (Millionrounds; every figure on the page links to its filing or article) - 1 [**Verily** Learn how Verily's AI-native data platform unifies complex health data with robust governance, accelerating research and care to deliver real-world impact for p](https://millionrounds.com/company/verily) Learn how Verily's AI-native data platform unifies complex health data with robust governance, accelerating research and care to deliver real-world impact for p *Founded* - South San Francisco, United States **$1.3B** last round Mar 2026 - 2 [**Structure Therapeutics** Structure Therapeutics specializes in the discovery and development of drugs against a type of targets called GPCR.](https://millionrounds.com/company/structure-therapeutics) Structure Therapeutics specializes in the discovery and development of drugs against a type of targets called GPCR. *Founded* 2016 South San Francisco, United States **$748M** last round Dec 2025 - 3 [**NewLimit** NewLimit is a biotechnology company based in South San Francisco, California, focused on extending human healthspan through innovative medicines that restore yo](https://millionrounds.com/company/newlimit) NewLimit is a biotechnology company based in South San Francisco, California, focused on extending human healthspan through innovative medicines that restore yo *Founded* 2022 South San Francisco, United States **$610M** last round Jun 2026 - 4 [**IDEAYA Biosciences** IDEAYA Biosciences is an oncology-focused biotechnology company that develops therapeutics for patients with genetically-defined cancers.](https://millionrounds.com/company/ideaya-biosciences) IDEAYA Biosciences is an oncology-focused biotechnology company that develops therapeutics for patients with genetically-defined cancers. *Founded* 2015 South San Francisco, United States **$608M** last round Jun 2026 - 5 [**Freenome** Freenome is a biotechnology company with a comprehensive multiomics platform for cancer detection using a routine blood draw.](https://millionrounds.com/company/freenome) Freenome is a biotechnology company with a comprehensive multiomics platform for cancer detection using a routine blood draw. *Founded* 2014 South San Francisco, United States **$553M** last round Jul 2026 - 6 [**ArsenalBio** ArsenalBio is a programmable cell therapy company that offers advanced CAR T-cell therapies for solid tumors.](https://millionrounds.com/company/arsenalbio) ArsenalBio is a programmable cell therapy company that offers advanced CAR T-cell therapies for solid tumors. *Founded* 2019 South San Francisco, United States **$410M** last round Sept 2024 - 7 [**Global Blood Therapeutics** GBT is a clinical-stage biopharmaceutical company developing a therapy for sickle cell disease.](https://millionrounds.com/company/global-blood-therapeutics) GBT is a clinical-stage biopharmaceutical company developing a therapy for sickle cell disease. *Founded* 2011 South San Francisco, United States **$389M** last round Dec 2021 - 8 [**Encoded Therapeutics** Encoded Therapeutics is a Harnessing the regulatory genome to create next-generation molecular therapies.](https://millionrounds.com/company/encoded-therapeutics) Encoded Therapeutics is a Harnessing the regulatory genome to create next-generation molecular therapies. *Founded* 2014 South San Francisco, United States **$379M** last round Sept 2026 - 9 [**Pliant Therapeutics** Pliant Therapeutics focuses on discovering, developing, and commercializing breakthrough treatments for fibrotic diseases.](https://millionrounds.com/company/pliant-therapeutics) Pliant Therapeutics focuses on discovering, developing, and commercializing breakthrough treatments for fibrotic diseases. *Founded* 2015 South San Francisco, United States **$350M** last round Jan 2023 - 10 [**NGM Biopharmaceuticals** NGM Biopharmaceuticals Inc.](https://millionrounds.com/company/ngm-biopharmaceuticals) NGM Biopharmaceuticals Inc. *Founded* 2008 South San Francisco, United States **$333M** last round Mar 2015 - 11 [**Tricida** Tricida operates in the healthcare industry focusing on pharmaceutical business.](https://millionrounds.com/company/tricida) Tricida operates in the healthcare industry focusing on pharmaceutical business. *Founded* 2013 South San Francisco, United States **$327M** last round Oct 2022 - 12 [**Star Therapeutics** Star Therapeutics is a clinical-stage biotechnology company based in South San Francisco, California, founded in 2018.](https://millionrounds.com/company/star-therapeutics) Star Therapeutics is a clinical-stage biotechnology company based in South San Francisco, California, founded in 2018. *Founded* 2018 South San Francisco, United States **$325M** last round Oct 2026 - 13 [**Allogene Therapeutics** Allogene Therapeutics is a biotechnology company catalyzing cancer treatment through the development of CAR T therapy.](https://millionrounds.com/company/allogene-therapeutics) Allogene Therapeutics is a biotechnology company catalyzing cancer treatment through the development of CAR T therapy. *Founded* 2017 South San Francisco, United States **$310M** last round Apr 2026 - 14 [**Terremoto Biosciences** Terremoto Biosciences is a clinical-stage biotechnology company founded in 2021, focused on covalent drug discovery and development.](https://millionrounds.com/company/terremoto-biosciences) Terremoto Biosciences is a clinical-stage biotechnology company founded in 2021, focused on covalent drug discovery and development. *Founded* 2021 South San Francisco, United States **$283M** last round Apr 2026 - 15 [**Vera Therapeutics** Vera Therapeutics is a biotechnology company developing innovative biologic therapeutics with transformative clinical potential.](https://millionrounds.com/company/vera-therapeutics) Vera Therapeutics is a biotechnology company developing innovative biologic therapeutics with transformative clinical potential. *Founded* 2016 South San Francisco, United States **$261M** last round Dec 2025 - 16 [**Surrozen** Surrozen is a biopharmaceutical that focuses on unlocking the body’s regenerative power to treat injury and disease.](https://millionrounds.com/company/surrozen) Surrozen is a biopharmaceutical that focuses on unlocking the body’s regenerative power to treat injury and disease. *Founded* 2015 South San Francisco, United States **$258M** last round Mar 2025 - 17 [**Cellares** Cellares is a biotechnology company based in South San Francisco, California, and is recognized as the world’s first Integrated Development and Manufacturing Or](https://millionrounds.com/company/cellares) Cellares is a biotechnology company based in South San Francisco, California, and is recognized as the world’s first Integrated Development and Manufacturing Or *Founded* 2019 South San Francisco, United States **$257M** last round Jan 2026 - 18 [**Rapt Therapeutics** Rapt is focused on the discovery and development of novel small-molecule agents to activate the immune system to eradicate cancer.](https://millionrounds.com/company/rapt-therapeutics) Rapt is focused on the discovery and development of novel small-molecule agents to activate the immune system to eradicate cancer. *Founded* 2015 South San Francisco, United States **$250M** last round Oct 2025 - 19 [**ORIC Pharmaceuticals** ORIC Pharmaceuticals is a biopharmaceutical company that develops treatments that target the causes of therapeutic resistance.](https://millionrounds.com/company/oric-pharmaceuticals) ORIC Pharmaceuticals is a biopharmaceutical company that develops treatments that target the causes of therapeutic resistance. *Founded* 2014 South San Francisco, United States **$248M** last round May 2025 - 20 [**Nkarta Therapeutics** Nkarta Therapeutics is a developer of cell engineering platform created to build the next generation of cell therapies.](https://millionrounds.com/company/nkarta-therapeutics) Nkarta Therapeutics is a developer of cell engineering platform created to build the next generation of cell therapies. *Founded* 2015 South San Francisco, United States **$240M** last round Mar 2024 - 21 [**InterVenn** InterVenn unlocks the glycoproteome using artificial intelligence for the development of transformational healthcare solutions in DX and Rx.](https://millionrounds.com/company/intervenn) InterVenn unlocks the glycoproteome using artificial intelligence for the development of transformational healthcare solutions in DX and Rx. *Founded* 2017 South San Francisco, United States **$210M** last round Aug 2021 - 22 [**Soley Therapeutics** Soley Therapeutics is a biotechnology company based in South San Francisco, California, focused on drug discovery and development.](https://millionrounds.com/company/soley-therapeutics) Soley Therapeutics is a biotechnology company based in South San Francisco, California, focused on drug discovery and development. *Founded* 2020 South San Francisco, United States **$200M** last round Jan 2026 - 23 [**Circle Pharma** Circle Pharma is a provider of a macrocycle development platform intended to provide macrocyclic peptides.](https://millionrounds.com/company/circle-pharma) Circle Pharma is a provider of a macrocycle development platform intended to provide macrocyclic peptides. *Founded* 2012 South San Francisco, United States **$187M** last round Sept 2026 - 24 [**Electra Therapeutics** Electra Therapeutics is a clinical-stage biotechnology company based in South San Francisco, California, founded in 2018.](https://millionrounds.com/company/electra-therapeutics) Electra Therapeutics is a clinical-stage biotechnology company based in South San Francisco, California, founded in 2018. *Founded* 2018 South San Francisco, United States **$183M** last round Oct 2025 - 25 [**Lycia Therapeutics** Lycia Therapeutics is a clinical-stage biotechnology company based in South San Francisco, California.](https://millionrounds.com/company/lycia-therapeutics) Lycia Therapeutics is a clinical-stage biotechnology company based in South San Francisco, California. *Founded* 2020 South San Francisco, United States **$182M** last round Jun 2026 - 26 [**Annexon Biosciences** Annexon Biosciences is a biotech company, discovering and developing novel therapeutics for neurodegenerative and autoimmune disorders.](https://millionrounds.com/company/annexon-biosciences) Annexon Biosciences is a biotech company, discovering and developing novel therapeutics for neurodegenerative and autoimmune disorders. *Founded* - South San Francisco, United States **$180M** last round Jul 2026 - 27 [**Senti Biosciences** Senti Biosciences is a biotechnology company that focuses on synthetic biology and gene circuit engineering for therapeutic applications.](https://millionrounds.com/company/senti-biosciences) Senti Biosciences is a biotechnology company that focuses on synthetic biology and gene circuit engineering for therapeutic applications. *Founded* 2016 South San Francisco, United States **$169M** last round May 2026 - 28 [**Harpoon Therapeutics** Harpoon Therapeutics is a clinical-stage immunotherapy company focused on the development of novel T-cell recruiting biologic therapies.](https://millionrounds.com/company/harpoon-therapeutics) Harpoon Therapeutics is a clinical-stage immunotherapy company focused on the development of novel T-cell recruiting biologic therapies. *Founded* 2015 South San Francisco, United States **$145M** last round Oct 2023 - 29 [**True North Therapeutics** True North Therapeutics is a pioneering biotechnology company selectively inhibiting the Complement pathway for diseases.](https://millionrounds.com/company/true-north-therapeutics) True North Therapeutics is a pioneering biotechnology company selectively inhibiting the Complement pathway for diseases. *Founded* 2013 South San Francisco, United States **$142M** last round Jan 2018 - 30 [**Nura Bio** Nura Bio is a clinical-stage biopharmaceutical company based in South San Francisco, California.](https://millionrounds.com/company/nura-bio) Nura Bio is a clinical-stage biopharmaceutical company based in South San Francisco, California. *Founded* 2018 South San Francisco, United States **$142M** last round Jun 2026 - 31 [**Quince Therapeutics** Quince Therapeutics is developing treatments for Alzheimer's and other degenerative disorders.](https://millionrounds.com/company/quince-therapeutics) Quince Therapeutics is developing treatments for Alzheimer's and other degenerative disorders. *Founded* 2012 South San Francisco, United States **$137M** last round May 2026 - 32 [**Quanta Therapeutics** Quanta Therapeutics, Inc.](https://millionrounds.com/company/quanta-therapeutics) Quanta Therapeutics, Inc. *Founded* 2018 South San Francisco, United States **$127M** last round Jun 2026 - 33 [**SonoThera** SonoThera is a biotechnology company based in South San Francisco that focuses on developing ultrasound-guided, nonviral gene therapies.](https://millionrounds.com/company/sonothera) SonoThera is a biotechnology company based in South San Francisco that focuses on developing ultrasound-guided, nonviral gene therapies. *Founded* 2021 South San Francisco, United States **$125M** last round Jun 2026 - 34 [**Hana Biosciences** Talon Therapeutics is a biopharmaceutical company develops and commercializes new and differentiated cancer therapies.](https://millionrounds.com/company/hana-biosciences) Talon Therapeutics is a biopharmaceutical company develops and commercializes new and differentiated cancer therapies. *Founded* 2002 South San Francisco, United States **$116M** last round Jun 2010 - 35 [**Calithera Biosciences** Calithera Biosciences is a pharmaceutical company developing novel small molecule therapeutics for the treatment of cancer.](https://millionrounds.com/company/calithera-biosciences) Calithera Biosciences is a pharmaceutical company developing novel small molecule therapeutics for the treatment of cancer. *Founded* 2010 South San Francisco, United States **$115M** last round Mar 2022 - 36 [**Trace Neuroscience** Launched in 2024, Trace Neuroscience is a biopharmaceutical company on a mission to expand the promise of genomic medicine for people living with neurodegenerat](https://millionrounds.com/company/trace-neuroscience) Launched in 2024, Trace Neuroscience is a biopharmaceutical company on a mission to expand the promise of genomic medicine for people living with neurodegenerat *Founded* 2024 South San Francisco, United States **$101M** last round Nov 2024 - 37 [**Addition Therapeutics** Addition Therapeutics develops RNA-only therapeutics using PRINT technology for genetic medicine.](https://millionrounds.com/company/addition-therapeutics) Addition Therapeutics develops RNA-only therapeutics using PRINT technology for genetic medicine. *Founded* - South San Francisco, United States **$100M** last round Dec 2025 - 38 [**Lyell Immunopharma** Lyell Immunopharma is an operator of a biotechnology company that develops cellular therapies to cure cancer.](https://millionrounds.com/company/lyell-immunopharma) Lyell Immunopharma is an operator of a biotechnology company that develops cellular therapies to cure cancer. *Founded* 2018 South San Francisco, United States **$100M** last round Jul 2025 - 39 [**Genome Medical** Genome Medical is a telegenomics technology and services company allowing access to genomic-based medicine.](https://millionrounds.com/company/genome-medical) Genome Medical is a telegenomics technology and services company allowing access to genomic-based medicine. *Founded* 2016 South San Francisco, United States **$98M** last round Sept 2024 - 40 [**Epicrispr Biotechnologies** Epicrispr Biotechnologies is a clinical-stage biotechnology company based in South San Francisco, California.](https://millionrounds.com/company/epicrispr-biotechnologies) Epicrispr Biotechnologies is a clinical-stage biotechnology company based in South San Francisco, California. *Founded* 2018 South San Francisco, United States **$90M** last round Aug 2026 - 41 [**Principia BioPharma** Principia Biopharma is dedicated to bringing oral therapies to patients with significant unmet medical needs in immunology & oncology.](https://millionrounds.com/company/principia-biopharma) Principia Biopharma is dedicated to bringing oral therapies to patients with significant unmet medical needs in immunology & oncology. *Founded* 2008 South San Francisco, United States **$90M** last round Aug 2015 - 42 [**Kezar Life Sciences** Kezar Life Sciences company focused on the discovery and development of drugs targeting protein homeostasis for autoimmune disorders](https://millionrounds.com/company/kezar-life-sciences) Kezar Life Sciences company focused on the discovery and development of drugs targeting protein homeostasis for autoimmune disorders *Founded* 2015 South San Francisco, United States **$85M** last round Oct 2022 - 43 [**Antiva Biosciences** Antiva Biosciences is a biopharmaceutical company developing therapeutics for the treatment of diseases caused by HPV infection.](https://millionrounds.com/company/antiva-biosciences) Antiva Biosciences is a biopharmaceutical company developing therapeutics for the treatment of diseases caused by HPV infection. *Founded* 2012 South San Francisco, United States **$75M** last round Apr 2023 - 44 [**PACT Pharma** PACT Pharma is a clinical-stage biopharmaceutical company based in South San Francisco, California, founded in 2016.](https://millionrounds.com/company/pact-pharma) PACT Pharma is a clinical-stage biopharmaceutical company based in South San Francisco, California, founded in 2016. *Founded* 2016 South San Francisco, United States **$75M** last round Jan 2020 - 45 [**Centivax** Centivax, Inc.](https://millionrounds.com/company/centivax) Centivax, Inc. *Founded* 2019 South San Francisco, United States **$71M** last round Feb 2026 - 46 [**Atara Biotherapeutics** Atara Biotherapeutics (Nasdaq: ATRA) is an off-the-shelf, allogeneic T-cell immunotherapy company.](https://millionrounds.com/company/atara-biotherapeutics) Atara Biotherapeutics (Nasdaq: ATRA) is an off-the-shelf, allogeneic T-cell immunotherapy company. *Founded* - South San Francisco, United States **$69M** last round May 2026 - 47 [**Shinobi Therapeutics** Shinobi Therapeutics develops immune-evasive iPS cell therapies for cancer treatment.](https://millionrounds.com/company/shinobi-therapeutics) Shinobi Therapeutics develops immune-evasive iPS cell therapies for cancer treatment. *Founded* 2023 South San Francisco, United States **$68M** last round Aug 2024 - 48 [**Vicinitas Therapeutics** Vicinitas Therapeutics is a biotechnology company founded in 2022 and based in South San Francisco, California.](https://millionrounds.com/company/vicinitas-therapeutics) Vicinitas Therapeutics is a biotechnology company founded in 2022 and based in South San Francisco, California. *Founded* 2022 South San Francisco, United States **$65M** last round Jul 2022 - 49 [**Dualitas Therapeutics** Dualitas Therapeutics is a biotechnology company based in South San Francisco, CA, founded in 2023.](https://millionrounds.com/company/dualitas-therapeutics) Dualitas Therapeutics is a biotechnology company based in South San Francisco, CA, founded in 2023. *Founded* 2023 South San Francisco, United States **$65M** last round Sept 2025 - 50 [**Link Cell Therapies** Link Cell Therapies is a biotechnology company based in South San Francisco, founded in 2022 by Stanford physicians Robbie Majzner, MD, and Crystal Mackall, MD.](https://millionrounds.com/company/link-cell-therapies) Link Cell Therapies is a biotechnology company based in South San Francisco, founded in 2022 by Stanford physicians Robbie Majzner, MD, and Crystal Mackall, MD. *Founded* 2022 South San Francisco, United States **$60M** last round Dec 2025 **Total funding** how the list is ranked **15 November 2026** updated nightly **Rounds we track** source: Millionrounds Companies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list. ## Who backed them? Open any company for its rounds and investors, or search the investors who back biotech startups in South San Francisco in the app, with filters, lists and exports. [Find their investors](https://millionrounds.com/login?join=1&next=/app/investors)[All top lists](https://millionrounds.com/top-lists) ## More biotech lists [See all](https://millionrounds.com/top-lists?t=Biotech) [*IL* *NH* *CS* **Biotech startups in Europe** 1,665 companies · $22B](https://millionrounds.com/top-lists/biotech-startups-europe)[*GV* *IL* *RM* **Biotech startups that raised in 2026** 896 companies · $37B in 2026](https://millionrounds.com/top-lists/biotech-startups-raised-2026)[*IL* *CS* *ON* **Biotech startups in the United Kingdom** 588 companies · $15B](https://millionrounds.com/top-lists/biotech-startups-united-kingdom)[*GV* *RM* *M* **Biotech startups in the United States that raised in 2026** 498 companies · $32B in 2026](https://millionrounds.com/top-lists/biotech-startups-united-states-raised-2026)[*NH* *DT* *E* **Biotech startups founded in 2018** 368 companies · $14B](https://millionrounds.com/top-lists/biotech-startups-founded-2018)[*NR* *LL* *ST* **Biotech startups founded in 2020** 337 companies · $7.0B](https://millionrounds.com/top-lists/biotech-startups-founded-2020)[*E* *ET* *NA* **Biotech startups founded in 2019** 336 companies · $11B](https://millionrounds.com/top-lists/biotech-startups-founded-2019)[*IL* *RB* *VS* **Biotech startups founded in 2021** 275 companies · $12B](https://millionrounds.com/top-lists/biotech-startups-founded-2021) ## More lists for South San Francisco [See all](https://millionrounds.com/top-lists?r=South%20San%20Francisco) [*V* *XT* *ST* **Startups in South San Francisco** 126 companies · $14B](https://millionrounds.com/top-lists/startups-south-san-francisco)[*V* *F* *A* **Healthcare startups in South San Francisco** 31 companies · $5.9B](https://millionrounds.com/top-lists/healthcare-startups-south-san-francisco)[*V* *XT* *I* **AI startups in South San Francisco** 16 companies · $2.9B](https://millionrounds.com/top-lists/ai-startups-south-san-francisco)[*NB* *MT* *OP* **Pharma startups in South San Francisco** 10 companies · $1.3B](https://millionrounds.com/top-lists/pharma-startups-south-san-francisco)