# Top 22 Biotech Startups in San Mateo by Funding (2026)

> The 22 best-funded biotech startups in San Mateo, ranked by total funding raised: $1.5B combined. With founding year, headquarters and each company's rounds.

Source: https://millionrounds.com/top-lists/biotech-startups-san-mateo (Millionrounds; every figure on the page links to its filing or article)

- 1 [**Bluejay Therapeutics** Bluejay Therapeutics is a private biopharmaceutical company focused on the development of cures for infectious diseases.](https://millionrounds.com/company/bluejay-therapeutics) Bluejay Therapeutics is a private biopharmaceutical company focused on the development of cures for infectious diseases. *Founded* 2019 San Mateo, United States **$182M** last round May 2024
- 2 [**Luma Health** Luma Health is a healthcare technology company founded in 2015 and based in San Mateo, California.](https://millionrounds.com/company/luma-health) Luma Health is a healthcare technology company founded in 2015 and based in San Mateo, California. *Founded* 2015 San Mateo, United States **$152M** last round Nov 2021
- 3 [**BigHat Biosciences** BigHat Biosciences is a biotechnology company founded in 2019 and based in San Mateo, California.](https://millionrounds.com/company/bighat-biosciences) BigHat Biosciences is a biotechnology company founded in 2019 and based in San Mateo, California. *Founded* 2019 San Mateo, United States **$150M** last round Sept 2026
- 4 [**Cala Health** Cala Health is a bioelectronic medicine company based in San Mateo, California, founded in 2013.](https://millionrounds.com/company/cala-health) Cala Health is a bioelectronic medicine company based in San Mateo, California, founded in 2013. *Founded* 2014 San Mateo, United States **$150M** last round Apr 2026
- 5 [**Notable** Notable is an AI-powered health start-up that automates and digitizes every physician-patient interaction.](https://millionrounds.com/company/notable) Notable is an AI-powered health start-up that automates and digitizes every physician-patient interaction. *Founded* 2017 San Mateo, United States **$145M** last round Jul 2026
- 6 [**AusperBio** AusperBio is a clinical-stage biopharmaceutical company dedicated to advancing treatments for hepatitis B virus (HBV) and developing oligonucleotide therapeutics.](https://millionrounds.com/company/ausperbio) AusperBio is a clinical-stage biopharmaceutical company dedicated to advancing treatments for hepatitis B virus (HBV) and developing oligonucleotide therapeutics. *Founded* 2019 San Mateo, United States **$113M** last round Sept 2025
- 7 [**CARGO Therapeutics** CARGO Therapeutics develops an adoptive cell therapy to benefit patients from potentially curative treatment options.](https://millionrounds.com/company/cargo-therapeutics) CARGO Therapeutics develops an adoptive cell therapy to benefit patients from potentially curative treatment options. *Founded* 2019 San Mateo, United States **$110M** last round May 2024
- 8 [**EpiBiologics** EpiBiologics is a biotechnology company based in San Mateo, California, founded in 2022.](https://millionrounds.com/company/epibiologics) EpiBiologics is a biotechnology company based in San Mateo, California, founded in 2022. *Founded* 2022 San Mateo, United States **$107M** last round Jan 2026
- 9 [**Kivu Bioscience** As a company focused on rapidly advancing next generation transformative assets, we leverage our expertise to efficiently progress programs to clinical proof of concept.](https://millionrounds.com/company/kivu-bioscience) As a company focused on rapidly advancing next generation transformative assets, we leverage our expertise to efficiently progress programs to clinical proof of concept. *Founded* 2024 San Mateo, United States **$92M** last round Oct 2024
- 10 [**Vivace Therapeutics** Vivace Therapeutics is a venture-backed start-up dedicated to discovering and developing cancer therapeutics by targeting a novel pathway.](https://millionrounds.com/company/vivace-therapeutics) Vivace Therapeutics is a venture-backed start-up dedicated to discovering and developing cancer therapeutics by targeting a novel pathway. *Founded* 2014 San Mateo, United States **$75M** last round Mar 2025
- 11 [**Route 92 Medical** Route 92 Medical is a medical device company developing a catheter to treat stroke.](https://millionrounds.com/company/route-92-medical) Route 92 Medical is a medical device company developing a catheter to treat stroke. *Founded* 2015 San Mateo, United States **$63M** last round Apr 2026
- 12 [**Evidation Health** We enable and empower everyone to participate in better health outcomes.](https://millionrounds.com/company/evidation-health) We enable and empower everyone to participate in better health outcomes. *Founded* 2012 San Mateo, United States **$61M** last round Aug 2018
- 13 [**Sagimet Biosciences** Sagimet Biosciences is a biotechnology company that focuses on developing novel therapeutics to treat important diseases.](https://millionrounds.com/company/sagimet-biosciences) Sagimet Biosciences is a biotechnology company that focuses on developing novel therapeutics to treat important diseases. *Founded* 2007 San Mateo, United States **$25M** last round Aug 2019
- 14 [**Lumiata** Lumiata was a healthcare-focused artificial intelligence company founded in 2013 in San Mateo, California.](https://millionrounds.com/company/lumiata) Lumiata was a healthcare-focused artificial intelligence company founded in 2013 in San Mateo, California. *Founded* 2013 San Mateo, United States **$21M** last round Jul 2018
- 15 [**SonoMotion** Sonomotion is a medical device manufacturing company that specializes in providing medical solutions for kidney stones disease.](https://millionrounds.com/company/sonomotion) Sonomotion is a medical device manufacturing company that specializes in providing medical solutions for kidney stones disease. *Founded* 2014 San Mateo, United States **$12M** last round Feb 2025
- 16 [**Food In-Depth** We do not know enough about what is in our food.](https://millionrounds.com/company/food-in-depth) We do not know enough about what is in our food. *Founded* 2015 San Mateo, United States **$12M** last round Feb 2021
- 17 [**Vynca** Vynca, also known as VyncaCare, is a healthcare technology company based in San Mateo, California.](https://millionrounds.com/company/vynca) Vynca, also known as VyncaCare, is a healthcare technology company based in San Mateo, California. *Founded* 2014 San Mateo, United States **$10M** last round Jun 2019
- 18 [**uLink Labs** uLink Labs is a medical device company that specializes in next-generation medical devices innovations.](https://millionrounds.com/company/ulink-labs) uLink Labs is a medical device company that specializes in next-generation medical devices innovations. *Founded* 2019 San Mateo, United States **$8.6M** last round Nov 2025
- 19 [**Maverix Biomics** Maverix Biomics is a biotechnology and bioinformatics company based in San Mateo, California.](https://millionrounds.com/company/maverix-biomics) Maverix Biomics is a biotechnology and bioinformatics company based in San Mateo, California. *Founded* 2012 San Mateo, United States **$6.0M** last round Jan 2014
- 20 [**NuMedii** NuMedii, Inc.](https://millionrounds.com/company/numedii) NuMedii, Inc. *Founded* 2008 San Mateo, United States **$5.5M** last round Aug 2015
- 21 [**Bespoke Biotherapeutics** Bespoke Biotherapeutics is a biotechnology company that provides engineered B-cell therapeutics.](https://millionrounds.com/company/bespoke-biotherapeutics) Bespoke Biotherapeutics is a biotechnology company that provides engineered B-cell therapeutics. *Founded* 2021 San Mateo, United States **$256K** last round Jun 2022
- 22 [**Genobank.io** GenoBank.io is a pioneering company that offers the first anonymous, privacy-preserving DNA test kit utilizing blockchain technology.](https://millionrounds.com/company/genobank-io) GenoBank.io is a pioneering company that offers the first anonymous, privacy-preserving DNA test kit utilizing blockchain technology. *Founded* 2018 San Mateo, United States **$50K** last round Oct 2022

**Total funding** how the list is ranked

**15 November 2026** updated nightly

**Rounds we track** source: Millionrounds

Companies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.

## Who backed them?

Open any company for its rounds and investors, or search the investors who back biotech startups in San Mateo in the app, with filters, lists and exports.

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## More biotech lists

[See all](https://millionrounds.com/top-lists?t=Biotech)

[*IL* *NH* *CS* **Biotech startups in Europe** 1,665 companies · $22B](https://millionrounds.com/top-lists/biotech-startups-europe)[*GV* *IL* *RM* **Biotech startups that raised in 2026** 896 companies · $37B in 2026](https://millionrounds.com/top-lists/biotech-startups-raised-2026)[*IL* *CS* *ON* **Biotech startups in the United Kingdom** 588 companies · $15B](https://millionrounds.com/top-lists/biotech-startups-united-kingdom)[*GV* *RM* *M* **Biotech startups in the United States that raised in 2026** 498 companies · $32B in 2026](https://millionrounds.com/top-lists/biotech-startups-united-states-raised-2026)[*NH* *DT* *E* **Biotech startups founded in 2018** 368 companies · $14B](https://millionrounds.com/top-lists/biotech-startups-founded-2018)[*NR* *LL* *ST* **Biotech startups founded in 2020** 337 companies · $7.0B](https://millionrounds.com/top-lists/biotech-startups-founded-2020)[*E* *ET* *NA* **Biotech startups founded in 2019** 336 companies · $11B](https://millionrounds.com/top-lists/biotech-startups-founded-2019)[*IL* *RB* *VS* **Biotech startups founded in 2021** 275 companies · $12B](https://millionrounds.com/top-lists/biotech-startups-founded-2021)

## More lists for San Mateo

[See all](https://millionrounds.com/top-lists?r=San%20Mateo)

[*S* *FA* *U* **Startups in San Mateo** 254 companies · $16B](https://millionrounds.com/top-lists/startups-san-mateo)[*S* *FA* *U* **AI startups in San Mateo** 48 companies · $12B](https://millionrounds.com/top-lists/ai-startups-san-mateo)[*I* *B* *S* **IT Services startups in San Mateo** 32 companies · $410M](https://millionrounds.com/top-lists/it-services-startups-san-mateo)[*S* *C* *S* **Big Data & Analytics startups in San Mateo** 29 companies · $6.1B](https://millionrounds.com/top-lists/big-data-startups-san-mateo)[*FA* *O* *T* **Software startups in San Mateo** 22 companies · $2.4B](https://millionrounds.com/top-lists/software-startups-san-mateo)[*LH* *CH* *N* **Healthcare startups in San Mateo** 19 companies · $939M](https://millionrounds.com/top-lists/healthcare-startups-san-mateo)[*R* *T* *N* **Internet startups in San Mateo** 11 companies · $504M](https://millionrounds.com/top-lists/internet-startups-san-mateo)[*V* *T* *B* **Cloud startups in San Mateo** 10 companies · $1.6B](https://millionrounds.com/top-lists/cloud-startups-san-mateo)