# Top 21 Biotech Startups in Pittsburgh by Funding (2026)

> The 21 best-funded biotech startups in Pittsburgh, ranked by total funding raised: $274M combined. With founding year, headquarters and each company's rounds.

Source: https://millionrounds.com/top-lists/biotech-startups-pittsburgh (Millionrounds; every figure on the page links to its filing or article)

- 1 [**Helomics** Helomics provides comprehensive tumor profiling utilizing proprietary tissue-based live cell and fixed cell products and services.](https://millionrounds.com/company/helomics) Helomics provides comprehensive tumor profiling utilizing proprietary tissue-based live cell and fixed cell products and services. *Founded* 1995 Pittsburgh, United States **$93M** last round Nov 2014
- 2 [**Peptilogics** Peptilogics is a clinical-stage biotechnology company based in Pittsburgh, Pennsylvania, focused on developing innovative surgical therapeutics and anti-biofilm](https://millionrounds.com/company/peptilogics) Peptilogics is a clinical-stage biotechnology company based in Pittsburgh, Pennsylvania, focused on developing innovative surgical therapeutics and anti-biofilm *Founded* 2013 Pittsburgh, United States **$84M** last round Oct 2025
- 3 [**ai3Bio** ai3Bio develops treatments to transform the lives of patients with cancer.](https://millionrounds.com/company/ai3bio) ai3Bio develops treatments to transform the lives of patients with cancer. *Founded* - Pittsburgh, United States **$48M** last round Sept 2026
- 4 [**Noveome Biotherapeutics** Noveome Biotherapeutics focuses on breakthrough therapies for the regenerative repair of inflamed or damaged tissues.](https://millionrounds.com/company/noveome-biotherapeutics) Noveome Biotherapeutics focuses on breakthrough therapies for the regenerative repair of inflamed or damaged tissues. *Founded* 2000 Pittsburgh, United States **$15M** last round Apr 2019
- 5 [**Cernostics** Cernostics is a life science company developing new molecular diagnostic tests to treat cancer.](https://millionrounds.com/company/cernostics) Cernostics is a life science company developing new molecular diagnostic tests to treat cancer. *Founded* 2008 Pittsburgh, United States **$12M** last round Mar 2018
- 6 [**Tissue Analytics** Securely stream patient photographs and wound analysis directly to your desktop!](https://millionrounds.com/company/tissue-analytics) Securely stream patient photographs and wound analysis directly to your desktop! *Founded* 2014 Pittsburgh, United States **$5.8M** last round Jan 2018
- 7 [**Duo Oncology** Duo Oncology develops a new nanoparticle technology specially tailored to penetrate established tumors.](https://millionrounds.com/company/duo-oncology) Duo Oncology develops a new nanoparticle technology specially tailored to penetrate established tumors. *Founded* 2020 Pittsburgh, United States **$4.6M** last round Aug 2026
- 8 [**Forest Devices** Forest Devices is a medical device startup that develops a novel stroke screening device designed to detect early signs of stokes.](https://millionrounds.com/company/forest-devices) Forest Devices is a medical device startup that develops a novel stroke screening device designed to detect early signs of stokes. *Founded* 2015 Pittsburgh, United States **$2.3M** last round Sept 2024
- 9 [**CytoAgents** CytoAgents is a biotechnology company focused on the the treatment of COVID-19, Influenza, and other viral infectious diseases.](https://millionrounds.com/company/cytoagents) CytoAgents is a biotechnology company focused on the the treatment of COVID-19, Influenza, and other viral infectious diseases. *Founded* 2018 Pittsburgh, United States **$2.3M** last round Oct 2025
- 10 [**LifeX** LifeX helps early-stage life sciences companies align commercialization, capital, infrastructure, and resources.](https://millionrounds.com/company/lifex) LifeX helps early-stage life sciences companies align commercialization, capital, infrastructure, and resources. *Founded* 2017 Pittsburgh, United States **$2.0M** last round Nov 2023
- 11 [**Renerva** Renerva is a rapidly-growing and innovative medical device company.](https://millionrounds.com/company/renerva) Renerva is a rapidly-growing and innovative medical device company. *Founded* 2017 Pittsburgh, United States **$1.3M** last round Sept 2025
- 12 [**Sharp Therapeutics** Sharp Therapeutics is a preclinical-stage biopharmaceutical company based in Pittsburgh, Pennsylvania.](https://millionrounds.com/company/sharp-therapeutics) Sharp Therapeutics is a preclinical-stage biopharmaceutical company based in Pittsburgh, Pennsylvania. *Founded* 2010 Pittsburgh, United States **$972K** last round Jul 2026
- 13 [**Sharp Edge Labs** Sharp Edge Labs is engaged in the development of biosensors for cellular biology research and high-throughput screening.](https://millionrounds.com/company/sharp-edge-labs) Sharp Edge Labs is engaged in the development of biosensors for cellular biology research and high-throughput screening. *Founded* 2010 Pittsburgh, United States **$950K** last round Aug 2014
- 14 [**Globin Solutions** Biotechnology company inspired by globin chemistry and protein engineering focused on developing breakthrough antidotal therapies.](https://millionrounds.com/company/globin-solutions) Biotechnology company inspired by globin chemistry and protein engineering focused on developing breakthrough antidotal therapies. *Founded* 2017 Pittsburgh, United States **$750K** last round Nov 2021
- 15 [**Myris Therapeutics** Myris Therapeutics is a privately held biotechnology company based in Pittsburgh, Pennsylvania.](https://millionrounds.com/company/myris-therapeutics) Myris Therapeutics is a privately held biotechnology company based in Pittsburgh, Pennsylvania. *Founded* 2016 Pittsburgh, United States **$500K** last round Oct 2026
- 16 [**Quantitative Medicine** Quantitative Medicine is a medical platform that is used to construct, assess, validate, and deploy drug models.](https://millionrounds.com/company/quantitative-medicine) Quantitative Medicine is a medical platform that is used to construct, assess, validate, and deploy drug models. *Founded* 2012 Pittsburgh, United States **$325K** last round Feb 2013
- 17 [**Vivasc Therapeutics** Vivasc Therapeutics is a drug development company that specializes in proprietary cardiac targeting peptide platform technology.](https://millionrounds.com/company/vivasc-therapeutics) Vivasc Therapeutics is a drug development company that specializes in proprietary cardiac targeting peptide platform technology. *Founded* 2019 Pittsburgh, United States **$284K** last round Oct 2022
- 18 [**BioHybrid Solutions** BioHybrid Solutions is a transformational platform company that develops next-generation nanoarmored protein-polymer conjugates.](https://millionrounds.com/company/biohybrid-solutions) BioHybrid Solutions is a transformational platform company that develops next-generation nanoarmored protein-polymer conjugates. *Founded* - Pittsburgh, United States **$200K** last round Dec 2023
- 19 [**Immunetrics** Immunetrics is a biotechnology and biosimulation company based in Pittsburgh, founded in 2001.](https://millionrounds.com/company/immunetrics) Immunetrics is a biotechnology and biosimulation company based in Pittsburgh, founded in 2001. *Founded* 2001 Pittsburgh, United States **$150K** last round Apr 2006
- 20 [**Astria Biosciences** Biotechnology company focused on diagnostics and therapeutics for cerebrovascular disease](https://millionrounds.com/company/astria-biosciences) Biotechnology company focused on diagnostics and therapeutics for cerebrovascular disease *Founded* - Pittsburgh, United States **$100K** last round Feb 2025
- 21 [**Resilient Lifescience** Resilient Lifescience is a medical technology startup based in Pittsburgh, Pennsylvania, founded in 2021.](https://millionrounds.com/company/resilient-lifescience) Resilient Lifescience is a medical technology startup based in Pittsburgh, Pennsylvania, founded in 2021. *Founded* 2022 Pittsburgh, United States **$50K** last round Dec 2023

**Total funding** how the list is ranked

**15 November 2026** updated nightly

**Rounds we track** source: Millionrounds

Companies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.

## Who backed them?

Open any company for its rounds and investors, or search the investors who back biotech startups in Pittsburgh in the app, with filters, lists and exports.

[Find their investors](https://millionrounds.com/login?join=1&next=/app/investors)[All top lists](https://millionrounds.com/top-lists)

## More biotech lists

[See all](https://millionrounds.com/top-lists?t=Biotech)

[*IL* *NH* *CS* **Biotech startups in Europe** 1,665 companies · $22B](https://millionrounds.com/top-lists/biotech-startups-europe)[*GV* *IL* *RM* **Biotech startups that raised in 2026** 896 companies · $37B in 2026](https://millionrounds.com/top-lists/biotech-startups-raised-2026)[*IL* *CS* *ON* **Biotech startups in the United Kingdom** 588 companies · $15B](https://millionrounds.com/top-lists/biotech-startups-united-kingdom)[*GV* *RM* *M* **Biotech startups in the United States that raised in 2026** 498 companies · $32B in 2026](https://millionrounds.com/top-lists/biotech-startups-united-states-raised-2026)[*NH* *DT* *E* **Biotech startups founded in 2018** 368 companies · $14B](https://millionrounds.com/top-lists/biotech-startups-founded-2018)[*NR* *LL* *ST* **Biotech startups founded in 2020** 337 companies · $7.0B](https://millionrounds.com/top-lists/biotech-startups-founded-2020)[*E* *ET* *NA* **Biotech startups founded in 2019** 336 companies · $11B](https://millionrounds.com/top-lists/biotech-startups-founded-2019)[*IL* *RB* *VS* **Biotech startups founded in 2021** 275 companies · $12B](https://millionrounds.com/top-lists/biotech-startups-founded-2021)

## More lists for Pittsburgh

[See all](https://millionrounds.com/top-lists?r=Pittsburgh)

[*SA* *SA* *K* **Startups in Pittsburgh** 198 companies · $5.1B](https://millionrounds.com/top-lists/startups-pittsburgh)[*SA* *SA* *GR* **AI startups in Pittsburgh** 32 companies · $3.3B](https://millionrounds.com/top-lists/ai-startups-pittsburgh)[*EC* *P* *N* **IT Services startups in Pittsburgh** 22 companies · $293M](https://millionrounds.com/top-lists/it-services-startups-pittsburgh)[*P* *M* *FR* **Healthcare startups in Pittsburgh** 16 companies · $238M](https://millionrounds.com/top-lists/healthcare-startups-pittsburgh)[*AS* *B* *DK* **Big Data & Analytics startups in Pittsburgh** 14 companies · $140M](https://millionrounds.com/top-lists/big-data-startups-pittsburgh)