# Top 24 Biotech Startups in Irvine by Funding (2026)

> The 24 best-funded biotech startups in Irvine, ranked by total funding raised: $1.3B combined. With founding year, headquarters and each company's rounds.

Source: https://millionrounds.com/top-lists/biotech-startups-irvine (Millionrounds; every figure on the page links to its filing or article)

- 1 [**Beta Bionics** Beta Bionics is a biotechnology company that develops an integrated bionic pancreas system called the iLet.](https://millionrounds.com/company/beta-bionics) Beta Bionics is a biotechnology company that develops an integrated bionic pancreas system called the iLet. *Founded* 2015 Irvine, United States **$296M** last round Sept 2026
- 2 [**CG Oncology** CG Oncology is a clinical-stage biopharmaceutical company focused on the development of oncolytic immunotherapies to combat cancer.](https://millionrounds.com/company/cg-oncology) CG Oncology is a clinical-stage biopharmaceutical company focused on the development of oncolytic immunotherapies to combat cancer. *Founded* 2010 Irvine, United States **$238M** last round Dec 2024
- 3 [**Evolus** Evolus medical aesthetics focused on providing physicians and their patients with expanded choices in aesthetic procedures and treatments.](https://millionrounds.com/company/evolus) Evolus medical aesthetics focused on providing physicians and their patients with expanded choices in aesthetic procedures and treatments. *Founded* 2012 Irvine, United States **$150M** last round May 2025
- 4 [**Cloudbreak Therapeutics** Cloudbreak Therapeutics is a clinical stage biotechnology company](https://millionrounds.com/company/cloudbreak-therapeutics) Cloudbreak Therapeutics is a clinical stage biotechnology company *Founded* 2015 Irvine, United States **$130M** last round Jan 2022
- 5 [**Ambros Therapeutics** Ambros Therapeutics is a clinical-stage biotechnology company.](https://millionrounds.com/company/ambros-therapeutics) Ambros Therapeutics is a clinical-stage biotechnology company. *Founded* - Irvine, United States **$125M** last round Dec 2025
- 6 [**Silverado** Silverado Senior Living, based in Irvine, California, specializes in memory care and assisted living for individuals with memory impairments, such as Alzheimer’](https://millionrounds.com/company/silverado) Silverado Senior Living, based in Irvine, California, specializes in memory care and assisted living for individuals with memory impairments, such as Alzheimer’ *Founded* 1996 Irvine, United States **$51M** last round Jun 2018
- 7 [**Vascular Dynamics** Vascular Dynamics is a medical device company founded in 2008 and headquartered in Irvine, California.](https://millionrounds.com/company/vascular-dynamics) Vascular Dynamics is a medical device company founded in 2008 and headquartered in Irvine, California. *Founded* 2008 Irvine, United States **$46M** last round Mar 2017
- 8 [**Agendia** Agendia is a molecular diagnostics company focused on precision oncology, specifically for early-stage breast cancer.](https://millionrounds.com/company/agendia) Agendia is a molecular diagnostics company focused on precision oncology, specifically for early-stage breast cancer. *Founded* 2003 Irvine, United States **$35M** last round Jul 2018
- 9 [**lensgen** LensGen creates adaptive intraocular lenses for the treatment of presbyopia.](https://millionrounds.com/company/lensgen) LensGen creates adaptive intraocular lenses for the treatment of presbyopia. *Founded* 2011 Irvine, United States **$34M** last round Aug 2020
- 10 [**TAE Life Sciences** TAE Life Sciences is a biotechnology company founded in 2017 and based in Irvine, California.](https://millionrounds.com/company/tae-life-sciences) TAE Life Sciences is a biotechnology company founded in 2017 and based in Irvine, California. *Founded* 2017 Irvine, United States **$30M** last round Jun 2020
- 11 [**Seragon Pharmaceuticals** Seragon Pharmaceuticals is a research-based company dedicated to improving human and animal health through innovative science.](https://millionrounds.com/company/seragon-pharmaceuticals) Seragon Pharmaceuticals is a research-based company dedicated to improving human and animal health through innovative science. *Founded* 2013 Irvine, United States **$30M** last round Oct 2013
- 12 [**Immunis, Inc.** Immunis, Inc.](https://millionrounds.com/company/immunis-inc) Immunis, Inc. *Founded* 2019 Irvine, United States **$25M** last round Jan 2025
- 13 [**Amberstone Biosciences** Amberstone Biosciences is a biotechnology company based in Irvine and Laguna Hills, California, founded in 2018.](https://millionrounds.com/company/amberstone-biosciences) Amberstone Biosciences is a biotechnology company based in Irvine and Laguna Hills, California, founded in 2018. *Founded* 2018 Irvine, United States **$12M** last round Jan 2022
- 14 [**Diality** Diality is a medical device company based in Irvine, California, focused on improving the care of patients with kidney disease.](https://millionrounds.com/company/diality) Diality is a medical device company based in Irvine, California, focused on improving the care of patients with kidney disease. *Founded* 2015 Irvine, United States **$10M** last round Nov 2019
- 15 [**Harbor MedTech** Harbor MedTech develops and commercializes tissue regeneration products for the treatment of chronic skin wounds.](https://millionrounds.com/company/harbor-medtech) Harbor MedTech develops and commercializes tissue regeneration products for the treatment of chronic skin wounds. *Founded* 2010 Irvine, United States **$9.3M** last round Oct 2016
- 16 [**Predictive Health Diagnostics Company** Predictive Health Diagnostics is a technology company that develops, manufactures, and distributes specialty diagnostic tests.](https://millionrounds.com/company/predictive-health-diagnostics-company) Predictive Health Diagnostics is a technology company that develops, manufactures, and distributes specialty diagnostic tests. *Founded* 2017 Irvine, United States **$8.3M** last round Jul 2021
- 17 [**AIVITA Biomedical** AIVITA Biomedical is is a medicine company develops commercial and clinical stage programs utilizing curative and regenerative medicines.](https://millionrounds.com/company/aivita-biomedical) AIVITA Biomedical is is a medicine company develops commercial and clinical stage programs utilizing curative and regenerative medicines. *Founded* 2016 Irvine, United States **$8.0M** last round Aug 2022
- 18 [**Somanta Pharmaceuticals** Somanta Pharmaceuticals is a development-stage biopharmaceutical company manufacturing therapeutic drugs for the treatment of cancer.](https://millionrounds.com/company/somanta-pharmaceuticals) Somanta Pharmaceuticals is a development-stage biopharmaceutical company manufacturing therapeutic drugs for the treatment of cancer. *Founded* 2001 Irvine, United States **$4.9M** last round Jan 2006
- 19 [**Capillary Biomedical** Capillary Biomedical is a medical device startup developing technologies for diabetes management.](https://millionrounds.com/company/capillary-biomedical) Capillary Biomedical is a medical device startup developing technologies for diabetes management. *Founded* 2014 Irvine, United States **$4.4M** last round Oct 2020
- 20 [**Nuravax** Nuravax develops and researches on vaccines, preventive solutions and treatment for neurodegenerative disorders.](https://millionrounds.com/company/nuravax) Nuravax develops and researches on vaccines, preventive solutions and treatment for neurodegenerative disorders. *Founded* - Irvine, United States **$3.0M** last round May 2025
- 21 [**OvaGene Oncology** OvaGene is an in-revenue growth company that develops and commercializes Molecular Diagnostics for women.](https://millionrounds.com/company/ovagene-oncology) OvaGene is an in-revenue growth company that develops and commercializes Molecular Diagnostics for women. *Founded* 2010 Irvine, United States **$2.1M** last round Mar 2012
- 22 [**University Lab Partners** University Lab Partners is a non-profit wet lab facility that helps companies by providing access to research capabilities and resources.](https://millionrounds.com/company/university-lab-partners) University Lab Partners is a non-profit wet lab facility that helps companies by providing access to research capabilities and resources. *Founded* 2019 Irvine, United States **$2.0M** last round Nov 2023
- 23 [**Vulcan Biologics** Vulcan Biologics provides a biotechnology platform that offers stable and persistent modulation of microbiomes.](https://millionrounds.com/company/vulcan-biologics) Vulcan Biologics provides a biotechnology platform that offers stable and persistent modulation of microbiomes. *Founded* 2019 Irvine, United States **$990K** last round Dec 2021
- 24 [**Aracari Biosciences** Aracari is a Drug discovery company.](https://millionrounds.com/company/aracari-biosciences) Aracari is a Drug discovery company. *Founded* 2019 Irvine, United States **$988K** last round Sept 2021

**Total funding** how the list is ranked

**15 November 2026** updated nightly

**Rounds we track** source: Millionrounds

Companies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.

## Who backed them?

Open any company for its rounds and investors, or search the investors who back biotech startups in Irvine in the app, with filters, lists and exports.

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## More biotech lists

[See all](https://millionrounds.com/top-lists?t=Biotech)

[*IL* *NH* *CS* **Biotech startups in Europe** 1,665 companies · $22B](https://millionrounds.com/top-lists/biotech-startups-europe)[*GV* *IL* *RM* **Biotech startups that raised in 2026** 896 companies · $37B in 2026](https://millionrounds.com/top-lists/biotech-startups-raised-2026)[*IL* *CS* *ON* **Biotech startups in the United Kingdom** 588 companies · $15B](https://millionrounds.com/top-lists/biotech-startups-united-kingdom)[*GV* *RM* *M* **Biotech startups in the United States that raised in 2026** 498 companies · $32B in 2026](https://millionrounds.com/top-lists/biotech-startups-united-states-raised-2026)[*NH* *DT* *E* **Biotech startups founded in 2018** 368 companies · $14B](https://millionrounds.com/top-lists/biotech-startups-founded-2018)[*NR* *LL* *ST* **Biotech startups founded in 2020** 337 companies · $7.0B](https://millionrounds.com/top-lists/biotech-startups-founded-2020)[*E* *ET* *NA* **Biotech startups founded in 2019** 336 companies · $11B](https://millionrounds.com/top-lists/biotech-startups-founded-2019)[*IL* *RB* *VS* **Biotech startups founded in 2021** 275 companies · $12B](https://millionrounds.com/top-lists/biotech-startups-founded-2021)

## More lists for Irvine

[See all](https://millionrounds.com/top-lists?r=Irvine)

[*R* *AH* *F* **Startups in Irvine** 166 companies · $16B](https://millionrounds.com/top-lists/startups-irvine)[*BB* *AM* *S* **Healthcare startups in Irvine** 25 companies · $807M](https://millionrounds.com/top-lists/healthcare-startups-irvine)[*L* *ZS* *C* **IT Services startups in Irvine** 18 companies · $116M](https://millionrounds.com/top-lists/it-services-startups-irvine)[*B* *U* *N* **Software startups in Irvine** 12 companies · $205M](https://millionrounds.com/top-lists/software-startups-irvine)[*F* *CC* *S* **AI startups in Irvine** 10 companies · $1.6B](https://millionrounds.com/top-lists/ai-startups-irvine)