# Top 14 Biotech Startups in Cleveland by Funding (2026)

> The 14 best-funded biotech startups in Cleveland, ranked by total funding raised: $225M combined. With founding year, headquarters and each company's rounds.

Source: https://millionrounds.com/top-lists/biotech-startups-cleveland (Millionrounds; every figure on the page links to its filing or article)

- 1 [**SPR Therapeutics** SPR Therapeutics is a medical device company.](https://millionrounds.com/company/spr-therapeutics) SPR Therapeutics is a medical device company. *Founded* 2010 Cleveland, United States **$101M** last round Feb 2024
- 2 [**Juventas Therapeutics** Juventas is a biotechnology company that discovers and develops non-viral gene therapies for the treatment of chronic cardiovascular diseases.](https://millionrounds.com/company/juventas-therapeutics) Juventas is a biotechnology company that discovers and develops non-viral gene therapies for the treatment of chronic cardiovascular diseases. *Founded* 2007 Cleveland, United States **$41M** last round May 2015
- 3 [**Checkpoint Surgical** Checkpoint Surgical provides physicians with medical devices to locate, evaluate, and protect nerves and muscles in surgical procedures.](https://millionrounds.com/company/checkpoint-surgical) Checkpoint Surgical provides physicians with medical devices to locate, evaluate, and protect nerves and muscles in surgical procedures. *Founded* 2009 Cleveland, United States **$23M** last round Jun 2024
- 4 [**Cleveland Diagnostics** Cleveland Diagnostics is a precision oncology and cancer biotechnology company based in Cleveland, Ohio.](https://millionrounds.com/company/cleveland-diagnostics) Cleveland Diagnostics is a precision oncology and cancer biotechnology company based in Cleveland, Ohio. *Founded* 2013 Cleveland, United States **$16M** last round Oct 2025
- 5 [**Athersys** Athersys is a clinical stage biopharmaceutical company with a growing pipeline of highly differentiated, potential best in class therapeutics to treat significa](https://millionrounds.com/company/athersys) Athersys is a clinical stage biopharmaceutical company with a growing pipeline of highly differentiated, potential best in class therapeutics to treat significa *Founded* 1995 Cleveland, United States **$9.0M** last round Mar 2012
- 6 [**Diasome Pharmaceuticals** Diasome Pharmaceuticals is a clinical-stage diabetes therapeutics company that designs and develops insulin-based therapies.](https://millionrounds.com/company/diasome-pharmaceuticals) Diasome Pharmaceuticals is a clinical-stage diabetes therapeutics company that designs and develops insulin-based therapies. *Founded* 2004 Cleveland, United States **$9.0M** last round Jun 2023
- 7 [**Complion** Complion is a clinical research software company based in Cleveland, Ohio, founded in 2013.](https://millionrounds.com/company/complion) Complion is a clinical research software company based in Cleveland, Ohio, founded in 2013. *Founded* 2013 Cleveland, United States **$8.7M** last round Feb 2019
- 8 [**Securus Medical Group** Securus Medical Group develops clinical tools for monitoring core body temperature within body cavities.](https://millionrounds.com/company/securus-medical-group) Securus Medical Group develops clinical tools for monitoring core body temperature within body cavities. *Founded* 2011 Cleveland, United States **$7.5M** last round Oct 2013
- 9 [**Cell X Technologies** Cell X Technologies is a leader in cell processing, specializing in the commercialization of autologous and allogeneic cell therapies.](https://millionrounds.com/company/cell-x-technologies) Cell X Technologies is a leader in cell processing, specializing in the commercialization of autologous and allogeneic cell therapies. *Founded* 2019 Cleveland, United States **$6.0M** last round Aug 2024
- 10 [**TPA Stream** TPA Stream is a SaaS company that delivers cloud-based claims data and software for next generation benefits.](https://millionrounds.com/company/tpa-stream) TPA Stream is a SaaS company that delivers cloud-based claims data and software for next generation benefits. *Founded* 2014 Cleveland, United States **$1.4M** last round Sept 2019
- 11 [**Milo Biotechnology** Milo Biotechnology develops technologies and programs to improve the lives of patients with neuromuscular diseases.](https://millionrounds.com/company/milo-biotechnology) Milo Biotechnology develops technologies and programs to improve the lives of patients with neuromuscular diseases. *Founded* 2011 Cleveland, United States **$1.1M** last round Sept 2016
- 12 [**Analiza** Analiza, Inc.](https://millionrounds.com/company/analiza) Analiza, Inc. *Founded* 1996 Cleveland, United States **$600K** last round Sept 2008
- 13 [**Affinity Therapeutics** Affinity Therapeutics is a research-driven biotech company focusing on the design and delivery of life-enhancing medical applications.](https://millionrounds.com/company/affinity-therapeutics) Affinity Therapeutics is a research-driven biotech company focusing on the design and delivery of life-enhancing medical applications. *Founded* 2010 Cleveland, United States **$400K** last round Jan 2014
- 14 [**Biochip Labs** Biochip Labs provides blood disorder testing for conditions like sickle cell disease and thalassemia.](https://millionrounds.com/company/biochip-labs) Biochip Labs provides blood disorder testing for conditions like sickle cell disease and thalassemia. *Founded* - Cleveland, United States **$150K** last round Jul 2023

**Total funding** how the list is ranked

**15 November 2026** updated nightly

**Rounds we track** source: Millionrounds

Companies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.

## Who backed them?

Open any company for its rounds and investors, or search the investors who back biotech startups in Cleveland in the app, with filters, lists and exports.

[Find their investors](https://millionrounds.com/login?join=1&next=/app/investors)[All top lists](https://millionrounds.com/top-lists)

## More biotech lists

[See all](https://millionrounds.com/top-lists?t=Biotech)

[*IL* *NH* *CS* **Biotech startups in Europe** 1,665 companies · $22B](https://millionrounds.com/top-lists/biotech-startups-europe)[*GV* *IL* *RM* **Biotech startups that raised in 2026** 896 companies · $37B in 2026](https://millionrounds.com/top-lists/biotech-startups-raised-2026)[*IL* *CS* *ON* **Biotech startups in the United Kingdom** 588 companies · $15B](https://millionrounds.com/top-lists/biotech-startups-united-kingdom)[*GV* *RM* *M* **Biotech startups in the United States that raised in 2026** 498 companies · $32B in 2026](https://millionrounds.com/top-lists/biotech-startups-united-states-raised-2026)[*NH* *DT* *E* **Biotech startups founded in 2018** 368 companies · $14B](https://millionrounds.com/top-lists/biotech-startups-founded-2018)[*NR* *LL* *ST* **Biotech startups founded in 2020** 337 companies · $7.0B](https://millionrounds.com/top-lists/biotech-startups-founded-2020)[*E* *ET* *NA* **Biotech startups founded in 2019** 336 companies · $11B](https://millionrounds.com/top-lists/biotech-startups-founded-2019)[*IL* *RB* *VS* **Biotech startups founded in 2021** 275 companies · $12B](https://millionrounds.com/top-lists/biotech-startups-founded-2021)

## More lists for Cleveland

[See all](https://millionrounds.com/top-lists?r=Cleveland)

[*F* *E* *ST* **Startups in Cleveland** 81 companies · $1.6B](https://millionrounds.com/top-lists/startups-cleveland)[*ST* *CS* *C* **Healthcare startups in Cleveland** 10 companies · $150M](https://millionrounds.com/top-lists/healthcare-startups-cleveland)