# Top 50 Biotech Startups in Cambridge by Funding (2026)

> The 50 best-funded biotech startups in Cambridge, ranked by total funding raised: $16B combined. With founding year, headquarters and each company's rounds.

Source: https://millionrounds.com/top-lists/biotech-startups-cambridge (Millionrounds; every figure on the page links to its filing or article)

- 1 [**Blueprint Medicines** Blueprint Medicines is a global, fully integrated biopharmaceutical company that invents life-changing medicines.](https://millionrounds.com/company/blueprint-medicines) Blueprint Medicines is a global, fully integrated biopharmaceutical company that invents life-changing medicines. *Founded* 2011 Cambridge, United States **$1.4B** last round Jun 2022
- 2 [**EQRx** EQRx is a biotechnology company that focuses on re-engineering the process of drug discovery to make them affordable.](https://millionrounds.com/company/eqrx) EQRx is a biotechnology company that focuses on re-engineering the process of drug discovery to make them affordable. *Founded* 2019 Cambridge, United States **$1.2B** last round Dec 2021
- 3 [**Relay Therapeutics** Relay therapeutics is a developer of an allosteric drug-discovery platform intended to apply computational techniques to protein motion.](https://millionrounds.com/company/relay-therapeutics) Relay therapeutics is a developer of an allosteric drug-discovery platform intended to apply computational techniques to protein motion. *Founded* 2016 Cambridge, United States **$932M** last round May 2026
- 4 [**Tango Therapeutics** Tango Therapeutics is a biotechnology company that is developing next generation cancer therapies.](https://millionrounds.com/company/tango-therapeutics) Tango Therapeutics is a biotechnology company that is developing next generation cancer therapies. *Founded* 2017 Cambridge, United States **$852M** last round Jun 2026
- 5 [**Kymera Therapeutics** Kymera Therapeutics is a biotechnology company that specializes in the field of targeted protein degradation.](https://millionrounds.com/company/kymera-therapeutics) Kymera Therapeutics is a biotechnology company that specializes in the field of targeted protein degradation. *Founded* 2017 Cambridge, United States **$799M** last round Dec 2025
- 6 [**Moderna** Learn how we’re changing the world of medicine.](https://millionrounds.com/company/moderna) Learn how we’re changing the world of medicine. *Founded* 2013 Cambridge, United States **$675M** last round Jun 2026
- 7 [**Flagship Pioneering** Pioneering Medicines is a biotechnology research agency providing biotechnology to life sciences services.](https://millionrounds.com/company/flagship-pioneering) Pioneering Medicines is a biotechnology research agency providing biotechnology to life sciences services. *Founded* 2000 Cambridge, United States **$618M** last round Dec 2017
- 8 [**Lila Sciences** Lila Sciences is a biotechnology company based in Cambridge, Massachusetts, founded in 2023 through a merger of two projects from Flagship Pioneering.](https://millionrounds.com/company/lila-sciences) Lila Sciences is a biotechnology company based in Cambridge, Massachusetts, founded in 2023 through a merger of two projects from Flagship Pioneering. *Founded* - Cambridge, United States **$551M** last round Jan 2026
- 9 [**Akero Therapeutics** Akero Therapeutics is a biotechnology company focused on reversing the NASH epidemic by restoring the body’s metabolism to a balanced state.](https://millionrounds.com/company/akero-therapeutics) Akero Therapeutics is a biotechnology company focused on reversing the NASH epidemic by restoring the body’s metabolism to a balanced state. *Founded* 2017 Cambridge, United States **$502M** last round Mar 2024
- 10 [**Nuvalent** Nuvalent is a biopharmaceutical company that develops targeted therapies for cancer by designing small-molecule medicines.](https://millionrounds.com/company/nuvalent) Nuvalent is a biopharmaceutical company that develops targeted therapies for cancer by designing small-molecule medicines. *Founded* 2017 Cambridge, United States **$500M** last round Nov 2025
- 11 [**Intellia Therapeutics** Intellia Therapeutics is a genome editing company that develops curative gene-editing treatments.](https://millionrounds.com/company/intellia-therapeutics) Intellia Therapeutics is a genome editing company that develops curative gene-editing treatments. *Founded* 2014 Cambridge, United States **$485M** last round Sept 2026
- 12 [**Laronde** Laronde develops an eRNA-based therapeutic platform that is capable of indicating diverse proteins inside the body.](https://millionrounds.com/company/laronde) Laronde develops an eRNA-based therapeutic platform that is capable of indicating diverse proteins inside the body. *Founded* 2017 Cambridge, United States **$440M** last round Aug 2021
- 13 [**Editas Medicine** Editas Medicine is a clinical-stage genome editing company that develops genomic medicines for serious diseases.](https://millionrounds.com/company/editas-medicine) Editas Medicine is a clinical-stage genome editing company that develops genomic medicines for serious diseases. *Founded* 2013 Cambridge, United States **$335M** last round May 2026
- 14 [**Beam Therapeutics** Beam Therapeutics is a biotechnology company developing precision genetic medicines through the use of base editing technology.](https://millionrounds.com/company/beam-therapeutics) Beam Therapeutics is a biotechnology company developing precision genetic medicines through the use of base editing technology. *Founded* 2017 Cambridge, United States **$322M** last round Feb 2026
- 15 [**Fulcrum Therapeutics** Fulcrum Therapeutics is a biotechnology company that focuses on identifying and treating rare genetic diseases at their root cause.](https://millionrounds.com/company/fulcrum-therapeutics) Fulcrum Therapeutics is a biotechnology company that focuses on identifying and treating rare genetic diseases at their root cause. *Founded* 2016 Cambridge, United States **$310M** last round Dec 2025
- 16 [**Rubius Therapeutics** Rubius has developed the technology to grow, genetically engineer and mature long-circulating Red-Cell Therapeutics.](https://millionrounds.com/company/rubius-therapeutics) Rubius has developed the technology to grow, genetically engineer and mature long-circulating Red-Cell Therapeutics. *Founded* 2013 Cambridge, United States **$300M** last round Mar 2021
- 17 [**ReNAgade Therapeutics** ReNAgade Therapeutics focuses on the boundless potential of RNA therapeutics to treat disease.](https://millionrounds.com/company/renagade-therapeutics) ReNAgade Therapeutics focuses on the boundless potential of RNA therapeutics to treat disease. *Founded* 2021 Cambridge, United States **$300M** last round May 2023
- 18 [**Strand Therapeutics** Strand Therapeutics is a biopharmaceutical company applying synthetic biology to RNA therapeutics to develop single dose mRNA treatments.](https://millionrounds.com/company/strand-therapeutics) Strand Therapeutics is a biopharmaceutical company applying synthetic biology to RNA therapeutics to develop single dose mRNA treatments. *Founded* 2017 Cambridge, United States **$267M** last round Mar 2026
- 19 [**Centessa Pharmaceuticals** Centessa Pharmaceuticals is a pharmaceutical company that focuses on drug development to address significant medical needs.](https://millionrounds.com/company/centessa-pharmaceuticals) Centessa Pharmaceuticals is a pharmaceutical company that focuses on drug development to address significant medical needs. *Founded* 2021 Cambridge, United States **$250M** last round Nov 2025
- 20 [**TriNetX** TriNetX is a health research network that connects drug discovery and development from pharmaceutical companies.](https://millionrounds.com/company/trinetx) TriNetX is a health research network that connects drug discovery and development from pharmaceutical companies. *Founded* 2013 Cambridge, United States **$240M** last round Apr 2026
- 21 [**LifeMine Therapeutics** LifeMine Therapeutics combines genomics with AI and synthetic biology to discover and develop a pipeline of novel medicines.](https://millionrounds.com/company/lifemine-therapeutics) LifeMine Therapeutics combines genomics with AI and synthetic biology to discover and develop a pipeline of novel medicines. *Founded* 2016 Cambridge, United States **$230M** last round Mar 2022
- 22 [**Orna Therapeutics** Orna Therapeutics is a biotechnology company that specializes in fully engineered circular RNA therapeutics to treat various diseases.](https://millionrounds.com/company/orna-therapeutics) Orna Therapeutics is a biotechnology company that specializes in fully engineered circular RNA therapeutics to treat various diseases. *Founded* 2019 Cambridge, United States **$221M** last round Aug 2022
- 23 [**Matchpoint Therapeutics** Matchpoint Therapeutics is a biotechnology company based in Cambridge, Massachusetts, founded in 2021.](https://millionrounds.com/company/matchpoint-therapeutics) Matchpoint Therapeutics is a biotechnology company based in Cambridge, Massachusetts, founded in 2021. *Founded* 2021 Cambridge, United States **$220M** last round Oct 2026
- 24 [**Obsidian Therapeutics** Obsidian Therapeutics is a developer of a next-generation cell and gene therapies created to extend adoptive immunotherapy.](https://millionrounds.com/company/obsidian-therapeutics) Obsidian Therapeutics is a developer of a next-generation cell and gene therapies created to extend adoptive immunotherapy. *Founded* 2015 Cambridge, United States **$210M** last round Apr 2024
- 25 [**Aviceda Therapeutics** Aviceda Therapeutics is a clinical-stage biotechnology company based in Cambridge, Massachusetts, founded in 2018.](https://millionrounds.com/company/aviceda-therapeutics) Aviceda Therapeutics is a clinical-stage biotechnology company based in Cambridge, Massachusetts, founded in 2018. *Founded* 2018 Cambridge, United States **$208M** last round Jan 2025
- 26 [**Voyager Therapeutics** Voyager Therapeutics is a biotechnology company specializing in gene therapy and neurology.](https://millionrounds.com/company/voyager-therapeutics) Voyager Therapeutics is a biotechnology company specializing in gene therapy and neurology. *Founded* 2013 Cambridge, United States **$205M** last round Jan 2024
- 27 [**Q32 Bio** Q32 Bio is a biotechnology company that develops treatments for patients with severe autoimmune and inflammatory diseases.](https://millionrounds.com/company/q32-bio) Q32 Bio is a biotechnology company that develops treatments for patients with severe autoimmune and inflammatory diseases. *Founded* - Cambridge, United States **$200M** last round Jul 2026
- 28 [**Spero Therapeutics** Spero Therapeutics develops therapeutics for treatment of gram-negative infections.](https://millionrounds.com/company/spero-therapeutics) Spero Therapeutics develops therapeutics for treatment of gram-negative infections. *Founded* 2013 Cambridge, United States **$199M** last round Jul 2026
- 29 [**CREATE Medicines** CREATE Medicines is a clinical-stage biotechnology company based in Cambridge, Massachusetts.](https://millionrounds.com/company/create-medicines) CREATE Medicines is a clinical-stage biotechnology company based in Cambridge, Massachusetts. *Founded* 2019 Cambridge, United States **$195M** last round May 2026
- 30 [**X4 Pharmaceuticals** X4 Pharmaceuticals is a clinical-stage oncology company developing oral small molecule CXCR4 antagonists for the treatment.](https://millionrounds.com/company/x4-pharmaceuticals) X4 Pharmaceuticals is a clinical-stage oncology company developing oral small molecule CXCR4 antagonists for the treatment. *Founded* 2012 Cambridge, United States **$193M** last round Oct 2025
- 31 [**Generation Bio** Generation Bio is a biotechnology company that develops genetic medicines to treat genetic disorders.](https://millionrounds.com/company/generation-bio) Generation Bio is a biotechnology company that develops genetic medicines to treat genetic disorders. *Founded* 2016 Cambridge, United States **$176M** last round Mar 2023
- 32 [**Amylyx Pharmaceuticals** Amylyx Pharmaceuticals specializes in providing solutions for Alzheimer’s and other diseases of the brain.](https://millionrounds.com/company/amylyx-pharmaceuticals) Amylyx Pharmaceuticals specializes in providing solutions for Alzheimer’s and other diseases of the brain. *Founded* 2014 Cambridge, United States **$175M** last round Sept 2025
- 33 [**Scholar Rock** Scholar Rock is a biopharmaceutical company that develops and discovers new medicines and treatments for the serious diseases.](https://millionrounds.com/company/scholar-rock) Scholar Rock is a biopharmaceutical company that develops and discovers new medicines and treatments for the serious diseases. *Founded* 2012 Cambridge, United States **$167M** last round Mar 2026
- 34 [**Ethyreal Bio** Ethyreal Bio is a biotechnology startup developing precision therapies for autoimmune thyroid disorders.](https://millionrounds.com/company/ethyreal-bio) Ethyreal Bio is a biotechnology startup developing precision therapies for autoimmune thyroid disorders. *Founded* - Cambridge, United States **$161M** last round Jun 2026
- 35 [**Black Diamond Therapeutics** Black Diamond Therapeutics is a medical company focused on analyzing genetically defined cancers.](https://millionrounds.com/company/black-diamond-therapeutics) Black Diamond Therapeutics is a medical company focused on analyzing genetically defined cancers. *Founded* 2016 Cambridge, United States **$160M** last round Jun 2023
- 36 [**GentiBio** GentiBio is a clinical-stage biotherapeutics company founded in 2020, focused on developing engineered regulatory T-cell therapies (EngTregs) to address Type 1](https://millionrounds.com/company/gentibio) GentiBio is a clinical-stage biotherapeutics company founded in 2020, focused on developing engineered regulatory T-cell therapies (EngTregs) to address Type 1 *Founded* 2020 Cambridge, United States **$157M** last round Aug 2021
- 37 [**AIRNA** AIRNA is a biotechnology company founded in 2021, focused on discovering and developing RNA editing therapeutics.](https://millionrounds.com/company/airna) AIRNA is a biotechnology company founded in 2021, focused on discovering and developing RNA editing therapeutics. *Founded* 2021 Cambridge, United States **$155M** last round Apr 2025
- 38 [**Alkeus Pharmaceuticals** Alkeus Pharmaceuticals is a Boston-based startup focused on treatments for serious ophthalmic conditions.](https://millionrounds.com/company/alkeus-pharmaceuticals) Alkeus Pharmaceuticals is a Boston-based startup focused on treatments for serious ophthalmic conditions. *Founded* 2011 Cambridge, United States **$150M** last round Jun 2023
- 39 [**MOMA Therapeutics** MOMA Therapeutics is a clinical-stage biotechnology company based in Cambridge, Massachusetts, founded in 2020.](https://millionrounds.com/company/moma-therapeutics) MOMA Therapeutics is a clinical-stage biotechnology company based in Cambridge, Massachusetts, founded in 2020. *Founded* 2020 Cambridge, United States **$150M** last round May 2022
- 40 [**Mersana Therapeutics** Mersana Therapeutics develops a biodegradable polymer platform Fleximer® which creates new and better medicines.](https://millionrounds.com/company/mersana-therapeutics) Mersana Therapeutics develops a biodegradable polymer platform Fleximer® which creates new and better medicines. *Founded* 2005 Cambridge, United States **$148M** last round Jun 2016
- 41 [**Vedanta Biosciences** Vedanta Biosciences creates microbiome-derived therapies to address immune and infectious diseases by modulating the gut microbiota.](https://millionrounds.com/company/vedanta-biosciences) Vedanta Biosciences creates microbiome-derived therapies to address immune and infectious diseases by modulating the gut microbiota. *Founded* 2010 Cambridge, United States **$143M** last round Apr 2024
- 42 [**BIND Therapeutics** BIND Therapeutics is a biotechnology company incorporated in 2006; Pfizer acquired substantially all of its assets in 2016.](https://millionrounds.com/company/bind-therapeutics) BIND Therapeutics is a biotechnology company incorporated in 2006; Pfizer acquired substantially all of its assets in 2016. *Founded* 2006 Cambridge, United States **$138M** last round Sept 2013
- 43 [**Broad Institute** The Broad Institute brings together a diverse group of individuals from across its partner institutions to confront biomedical challenges.](https://millionrounds.com/company/broad-institute) The Broad Institute brings together a diverse group of individuals from across its partner institutions to confront biomedical challenges. *Founded* 2003 Cambridge, United States **$133M** last round Nov 2013
- 44 [**ARTBIO** ARTBIO is a clinical-stage biotechnology company founded in 2021, focused on developing alpha radioligand therapies for targeted cancer treatment.](https://millionrounds.com/company/artbio) ARTBIO is a clinical-stage biotechnology company founded in 2021, focused on developing alpha radioligand therapies for targeted cancer treatment. *Founded* 2021 Cambridge, United States **$132M** last round Jul 2025
- 45 [**Vigil Neuroscience** Vigil Neuroscience is a biotechnology company that develops novel therapeutics for neurodegenerative diseases.](https://millionrounds.com/company/vigil-neuroscience) Vigil Neuroscience is a biotechnology company that develops novel therapeutics for neurodegenerative diseases. *Founded* 2020 Cambridge, United States **$130M** last round Jun 2024
- 46 [**Acrivon Therapeutics** Acrivon Therapeutics is a precision oncology therapeutics company specializing in drug development through early clinical treatment success.](https://millionrounds.com/company/acrivon-therapeutics) Acrivon Therapeutics is a precision oncology therapeutics company specializing in drug development through early clinical treatment success. *Founded* 2018 Cambridge, United States **$130M** last round Apr 2024
- 47 [**C4 Therapeutics** C4 Therapeutics develops novel early stage therapies that eliminate disease-causing proteins.](https://millionrounds.com/company/c4-therapeutics) C4 Therapeutics develops novel early stage therapies that eliminate disease-causing proteins. *Founded* 2015 Cambridge, United States **$125M** last round Oct 2025
- 48 [**2seventy bio** 2seventy bio is an immuno-oncology cell therapy company that discovers and develops cancer therapies.](https://millionrounds.com/company/2seventy-bio) 2seventy bio is an immuno-oncology cell therapy company that discovers and develops cancer therapies. *Founded* 2021 Cambridge, United States **$125M** last round Feb 2023
- 49 [**Senda Biosciences** Senda Biosciences is a therapeutics platform company leveraging unprecedented insights into the molecular connections between humans.](https://millionrounds.com/company/senda-biosciences) Senda Biosciences is a therapeutics platform company leveraging unprecedented insights into the molecular connections between humans. *Founded* 2017 Cambridge, United States **$123M** last round Aug 2022
- 50 [**Merida Biosciences** Merida Biosciences is a biotechnology company based in Cambridge, Massachusetts, focused on developing precision medicines for autoimmune and allergic diseases.](https://millionrounds.com/company/merida-biosciences) Merida Biosciences is a biotechnology company based in Cambridge, Massachusetts, focused on developing precision medicines for autoimmune and allergic diseases. *Founded* 2022 Cambridge, United States **$121M** last round Apr 2025

**Total funding** how the list is ranked

**15 November 2026** updated nightly

**Rounds we track** source: Millionrounds

Companies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.

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