# Top 50 B2B Startups in San Francisco by Funding (2026)

> The 50 best-funded B2B startups in San Francisco, ranked by total funding raised: $1.2B combined. With founding year, headquarters and each company's rounds.

Source: https://millionrounds.com/top-lists/b2b-startups-san-francisco (Millionrounds; every figure on the page links to its filing or article)

- 1 [**Twist Bioscience** Twist Bioscience is a biotechnology company that offers synthetic DNA solutions, gene synthesis, and variant libraries.](https://millionrounds.com/company/twist-bioscience) Twist Bioscience is a biotechnology company that offers synthetic DNA solutions, gene synthesis, and variant libraries. *Founded* 2013 San Francisco, United States **$332M** last round Feb 2022
- 2 [**Lassie** We're building the operating system for independent doctors.](https://millionrounds.com/company/lassie) We're building the operating system for independent doctors. *Founded* - San Francisco, United States **$135M** last round Jun 2026
- 3 [**Sendoso** Sendoso is a leading B2B corporate gifting and direct mail platform, founded in 2016 and based in San Francisco, California.](https://millionrounds.com/company/sendoso) Sendoso is a leading B2B corporate gifting and direct mail platform, founded in 2016 and based in San Francisco, California. *Founded* 2016 San Francisco, United States **$111M** last round Sept 2021
- 4 [**Parafin** Growing small businesses through embedded financial services enabled on the very platforms on which SMBs sell & transact](https://millionrounds.com/company/parafin) Growing small businesses through embedded financial services enabled on the very platforms on which SMBs sell & transact *Founded* 2020 San Francisco, United States **$100M** last round May 2026
- 5 [**SideGuide** Building developer experience tools of the future](https://millionrounds.com/company/sideguide) Building developer experience tools of the future *Founded* 2022 San Francisco, United States **$83M** last round Sept 2026
- 6 [**MURAL** Mural is an AI-powered visual workspace platform that enhances team collaboration by connecting strategy to execution in a shared digital environment.](https://millionrounds.com/company/mural) Mural is an AI-powered visual workspace platform that enhances team collaboration by connecting strategy to execution in a shared digital environment. *Founded* 2011 San Francisco, United States **$67M** last round Oct 2026
- 7 [**Bravado** Bravado is a global music merchandise and brand management company, operating as a subsidiary of Universal Music Group.](https://millionrounds.com/company/bravado) Bravado is a global music merchandise and brand management company, operating as a subsidiary of Universal Music Group. *Founded* 2017 San Francisco, United States **$38M** last round May 2022
- 8 [**Demostack** Demostack is a cloud-based demo experience platform founded in 2020, headquartered in San Francisco, California.](https://millionrounds.com/company/demostack) Demostack is a cloud-based demo experience platform founded in 2020, headquartered in San Francisco, California. *Founded* 2020 San Francisco, United States **$34M** last round Apr 2022
- 9 [**UpCounsel** UpCounsel is a San Francisco-based online marketplace for legal services, founded in 2012.](https://millionrounds.com/company/upcounsel) UpCounsel is a San Francisco-based online marketplace for legal services, founded in 2012. *Founded* 2012 San Francisco, United States **$30M** last round Dec 2021
- 10 [**Rattle** Rattle Software Inc.](https://millionrounds.com/company/rattle) Rattle Software Inc. *Founded* 2020 San Francisco, United States **$26M** last round Apr 2022
- 11 [**Trendsi** Trendsi is a B2B dropshipping platform that specializes in fashion, allowing businesses to sell clothing and jewelry without the need to hold inventory.](https://millionrounds.com/company/trendsi) Trendsi is a B2B dropshipping platform that specializes in fashion, allowing businesses to sell clothing and jewelry without the need to hold inventory. *Founded* 2020 San Francisco, United States **$25M** last round Oct 2022
- 12 [**Recurrency** Recurrency is a technology company based in San Francisco that specializes in ERP (Enterprise Resource Planning) automation for growing wholesale distributors a](https://millionrounds.com/company/recurrency) Recurrency is a technology company based in San Francisco that specializes in ERP (Enterprise Resource Planning) automation for growing wholesale distributors a *Founded* 2019 San Francisco, United States **$22M** last round Feb 2023
- 13 [**PushPress** PushPress is a gym management software company founded in 2011, designed specifically for independent fitness businesses.](https://millionrounds.com/company/pushpress) PushPress is a gym management software company founded in 2011, designed specifically for independent fitness businesses. *Founded* 2011 San Francisco, United States **$20M** last round Oct 2024
- 14 [**Uiflow** Uiflow is a no-code platform that allows enterprises to quickly build production-ready applications without extensive coding.](https://millionrounds.com/company/uiflow) Uiflow is a no-code platform that allows enterprises to quickly build production-ready applications without extensive coding. *Founded* 2020 San Francisco, United States **$15M** last round Sept 2022
- 15 [**Suger** Suger is an API-first Software-as-a-Service (SaaS) platform that helps B2B software companies streamline their Cloud Go-to-Market (Cloud GTM) strategies.](https://millionrounds.com/company/suger) Suger is an API-first Software-as-a-Service (SaaS) platform that helps B2B software companies streamline their Cloud Go-to-Market (Cloud GTM) strategies. *Founded* 2022 San Francisco, United States **$15M** last round Feb 2025
- 16 [**Jiga** Jiga is an AI-powered sourcing platform founded in 2020 that connects engineers directly with vetted manufacturers.](https://millionrounds.com/company/jiga) Jiga is an AI-powered sourcing platform founded in 2020 that connects engineers directly with vetted manufacturers. *Founded* 2020 San Francisco, United States **$12M** last round Nov 2025
- 17 [**Triangle** Triangle is a software company that builds web3 wallet infrastructure for defi, NFTs, payments, social, and gaming.](https://millionrounds.com/company/triangle) Triangle is a software company that builds web3 wallet infrastructure for defi, NFTs, payments, social, and gaming. *Founded* 2022 San Francisco, United States **$12M** last round Aug 2026
- 18 [**Outbuild** Outbuild is a construction technology company based in San Francisco, founded in 2021.](https://millionrounds.com/company/outbuild) Outbuild is a construction technology company based in San Francisco, founded in 2021. *Founded* 2021 San Francisco, United States **$11M** last round Nov 2024
- 19 [**Wheel the World** Wheel the World is a technology-enabled travel platform dedicated to making travel accessible for individuals with disabilities, seniors, and their companions.](https://millionrounds.com/company/wheel-the-world) Wheel the World is a technology-enabled travel platform dedicated to making travel accessible for individuals with disabilities, seniors, and their companions. *Founded* 2018 San Francisco, United States **$11M** last round Feb 2026
- 20 [**ChangeEngine** ChangeEngine is a San Francisco-based SaaS technology company founded in September 2021.](https://millionrounds.com/company/changeengine) ChangeEngine is a San Francisco-based SaaS technology company founded in September 2021. *Founded* 2021 San Francisco, United States **$10M** last round May 2024
- 21 [**Foundation** Foundation, Inc.](https://millionrounds.com/company/foundation) Foundation, Inc. *Founded* 2023 San Francisco, United States **$9.4M** last round May 2026
- 22 [**ZeroPath** ZeroPath is an AI-native application security platform founded in 2024 by former security engineers from Tesla and Google.](https://millionrounds.com/company/zeropath) ZeroPath is an AI-native application security platform founded in 2024 by former security engineers from Tesla and Google. *Founded* 2024 San Francisco, United States **$5.0M** last round Sept 2025
- 23 [**Byteboard** Byteboard redesigns technical interviews to be more reflective of what engineers do on the job through.](https://millionrounds.com/company/byteboard) Byteboard redesigns technical interviews to be more reflective of what engineers do on the job through. *Founded* 2018 San Francisco, United States **$5.0M** last round Jan 2022
- 24 [**Enable Us** Enable Us is the most versatile buyer-centric enablement platform built to make the buying experience more efficient, transparent & personal](https://millionrounds.com/company/enable-us) Enable Us is the most versatile buyer-centric enablement platform built to make the buying experience more efficient, transparent & personal *Founded* 2020 San Francisco, United States **$4.5M** last round Dec 2021
- 25 [**Response** Response is a technology-driven company based in San Francisco, California, specializing in procurement management, indirect spend control, and supply chain optimization.](https://millionrounds.com/company/response) Response is a technology-driven company based in San Francisco, California, specializing in procurement management, indirect spend control, and supply chain optimization. *Founded* 2019 San Francisco, United States **$4.2M** last round Feb 2025
- 26 [**Alguna** Alguna is an AI-native revenue management platform founded in 2023 and headquartered in San Francisco.](https://millionrounds.com/company/alguna) Alguna is an AI-native revenue management platform founded in 2023 and headquartered in San Francisco. *Founded* 2023 San Francisco, United States **$4.0M** last round Sept 2025
- 27 [**PartnerSlate** PartnerSlate is a B2B marketplace and discovery platform tailored for consumer packaged goods (CPG) companies, particularly in the food and beverage sector.](https://millionrounds.com/company/partnerslate) PartnerSlate is a B2B marketplace and discovery platform tailored for consumer packaged goods (CPG) companies, particularly in the food and beverage sector. *Founded* 2015 San Francisco, United States **$4.0M** last round Jun 2023
- 28 [**Deltagen** DeltaGen is a private SaaS company founded in 2024, with headquarters in the United States and locations in San Francisco and Prague.](https://millionrounds.com/company/deltagen) DeltaGen is a private SaaS company founded in 2024, with headquarters in the United States and locations in San Francisco and Prague. *Founded* 2024 San Francisco, United States **$4.0M** last round Nov 2024
- 29 [**Astrada** Astrada is a software company that provides financial infrastructure, payments, and automation services.](https://millionrounds.com/company/astrada) Astrada is a software company that provides financial infrastructure, payments, and automation services. *Founded* - San Francisco, United States **$3.8M** last round May 2026
- 30 [**Builtfirst** Builtfirst is a developer of multi-use partner marketplace platform.](https://millionrounds.com/company/builtfirst) Builtfirst is a developer of multi-use partner marketplace platform. *Founded* 2020 San Francisco, United States **$3.8M** last round Dec 2021
- 31 [**BoomerangAI** BoomerangAI is a B2B SaaS platform founded in 2021, specializing in relationship-led revenue and go-to-market (GTM) data automation.](https://millionrounds.com/company/boomerangai) BoomerangAI is a B2B SaaS platform founded in 2021, specializing in relationship-led revenue and go-to-market (GTM) data automation. *Founded* 2023 San Francisco, United States **$3.7M** last round Mar 2022
- 32 [**Minoa** Minoa is a San Francisco-based B2B SaaS company founded in 2022.](https://millionrounds.com/company/minoa) Minoa is a San Francisco-based B2B SaaS company founded in 2022. *Founded* 2023 San Francisco, United States **$2.7M** last round May 2023
- 33 [**Bzaar** BZAAR is a B2B cross-border marketplace founded in 2020 by Nishant Verman and Prasanth Nair, both former Flipkart employees.](https://millionrounds.com/company/bzaar) BZAAR is a B2B cross-border marketplace founded in 2020 by Nishant Verman and Prasanth Nair, both former Flipkart employees. *Founded* 2020 San Francisco, United States **$2.7M** last round Aug 2023
- 34 [**Sendbloom** Sendbloom is a sales automation platform founded in 2013 and based in San Francisco, California.](https://millionrounds.com/company/sendbloom) Sendbloom is a sales automation platform founded in 2013 and based in San Francisco, California. *Founded* 2013 San Francisco, United States **$2.6M** last round Jan 2015
- 35 [**Voicepanel** Voicepanel is an AI-powered user research platform founded in 2023 and based in San Francisco, California.](https://millionrounds.com/company/voicepanel) Voicepanel is an AI-powered user research platform founded in 2023 and based in San Francisco, California. *Founded* 2023 San Francisco, United States **$2.4M** last round May 2024
- 36 [**Strategikon Pharma** Clinical MaestroTM by Strategikon Pharma is the only commercially available software platform for clinical trial business management.](https://millionrounds.com/company/strategikon-pharma) Clinical MaestroTM by Strategikon Pharma is the only commercially available software platform for clinical trial business management. *Founded* 2017 San Francisco, United States **$2.3M** last round Jun 2025
- 37 [**SlashExperts** SlashExperts is a B2B software company based in San Francisco, founded in 2024.](https://millionrounds.com/company/slashexperts) SlashExperts is a B2B software company based in San Francisco, founded in 2024. *Founded* 2024 San Francisco, United States **$2.0M** last round Apr 2025
- 38 [**Channel99** Channel99 is a B2B performance marketing platform founded in 2022.](https://millionrounds.com/company/channel99) Channel99 is a B2B performance marketing platform founded in 2022. *Founded* 2022 San Francisco, United States **$1.6M** last round Oct 2025
- 39 [**Ravacan** RAVACAN is a software company that specializes in direct sourcing and supply operations.](https://millionrounds.com/company/ravacan) RAVACAN is a software company that specializes in direct sourcing and supply operations. *Founded* 2019 San Francisco, United States **$1.6M** last round Oct 2020
- 40 [**Vently** Vently helps hosts engage, monetize, manage ticketing, and grow communities with end-to-end management tools.](https://millionrounds.com/company/vently) Vently helps hosts engage, monetize, manage ticketing, and grow communities with end-to-end management tools. *Founded* 2023 San Francisco, United States **$1.2M** last round Oct 2024
- 41 [**Vaero** Personalize writing styles of LLMs](https://millionrounds.com/company/vaero) Personalize writing styles of LLMs *Founded* 2023 San Francisco, United States **$1.2M** last round Apr 2023
- 42 [**Soptle** Soptle is a High growth financial technology company providing access to fair and low cost credit to SMBs](https://millionrounds.com/company/soptle) Soptle is a High growth financial technology company providing access to fair and low cost credit to SMBs *Founded* 2021 San Francisco, United States **$1.0M** last round May 2023
- 43 [**Durate** Durate is a healthcare technology company that specializes in automating physician scheduling for various healthcare settings, including hospitals, clinics, and](https://millionrounds.com/company/durate) Durate is a healthcare technology company that specializes in automating physician scheduling for various healthcare settings, including hospitals, clinics, and *Founded* 2024 San Francisco, United States **$500K** last round Dec 2024
- 44 [**CraftOS** At CraftOS, we understand the challenges faced by small craft beverage suppliers and buyers alike.](https://millionrounds.com/company/craftos) At CraftOS, we understand the challenges faced by small craft beverage suppliers and buyers alike. *Founded* 2023 San Francisco, United States **$500K** last round Sept 2023
- 45 [**Shor (YC S25)** Shor is a Y Combinator company founded in 2025, based in San Francisco.](https://millionrounds.com/company/shor-yc-s25) Shor is a Y Combinator company founded in 2025, based in San Francisco. *Founded* 2025 San Francisco, United States **$500K** last round Jul 2025
- 46 [**Cerulion** Cerulion is a robotics software company that develops an open-source, Rust-based middleware platform designed for robots and real-time systems.](https://millionrounds.com/company/cerulion) Cerulion is a robotics software company that develops an open-source, Rust-based middleware platform designed for robots and real-time systems. *Founded* - San Francisco, United States **$500K** last round Jan 2026
- 47 [**Vora AI** Vora supplies each hiring manager with an artificial intelligence-powered recruiting assistant.](https://millionrounds.com/company/vora-ai) Vora supplies each hiring manager with an artificial intelligence-powered recruiting assistant. *Founded* - San Francisco, United States **$500K** last round Mar 2025
- 48 [**Vovana** Vovana is an AI recruitment platform that allows users to automate the sourcing and screening of candidates.](https://millionrounds.com/company/vovana) Vovana is an AI recruitment platform that allows users to automate the sourcing and screening of candidates. *Founded* - San Francisco, United States **$500K** last round Mar 2025
- 49 [**Snowpilot** Snowpilot connects data from your SaaS tools, that allows run important workflows without needing an engineer.](https://millionrounds.com/company/snowpilot) Snowpilot connects data from your SaaS tools, that allows run important workflows without needing an engineer. *Founded* - San Francisco, United States **$500K** last round Sept 2024
- 50 [**Soff** Soff is an AI-powered supply chain operating system founded in 2024 and headquartered in San Francisco, California.](https://millionrounds.com/company/soff) Soff is an AI-powered supply chain operating system founded in 2024 and headquartered in San Francisco, California. *Founded* - San Francisco, United States **$500K** last round Sept 2024

**Total funding** how the list is ranked

**15 November 2026** updated nightly

**Rounds we track** source: Millionrounds

Companies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.

## Who backed them?

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## More b2b lists

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