# Top 31 AI Startups in San Diego by Funding (2026)

> The 31 best-funded AI startups in San Diego, ranked by total funding raised: $7.6B combined. With founding year, headquarters and each company's rounds.

Source: https://millionrounds.com/top-lists/ai-startups-san-diego (Millionrounds; every figure on the page links to its filing or article)

- 1 [**Shield AI** Shield AI is an artificial intelligence company that aims to protect service members and civilians with intelligent systems.](https://millionrounds.com/company/shield-ai) Shield AI is an artificial intelligence company that aims to protect service members and civilians with intelligent systems. *Founded* 2015 San Diego, United States **$7.0B** last round Nov 2026
- 2 [**Netradyne** Netradyne is a technology company based in San Diego, California, specializing in artificial intelligence, computer vision, and edge computing to enhance fleet](https://millionrounds.com/company/netradyne) Netradyne is a technology company based in San Diego, California, specializing in artificial intelligence, computer vision, and edge computing to enhance fleet *Founded* 2015 San Diego, United States **$127M** last round Jan 2025
- 3 [**Brain Corp** Brain Corp is a San Diego-based company founded in 2009, specializing in autonomous technology and robotic AI software.](https://millionrounds.com/company/brain-corp) Brain Corp is a San Diego-based company founded in 2009, specializing in autonomous technology and robotic AI software. *Founded* 2009 San Diego, United States **$114M** last round Jul 2016
- 4 [**KnuEdge** KnuEdge Inc.](https://millionrounds.com/company/knuedge) KnuEdge Inc. *Founded* 2005 San Diego, United States **$100M** last round Jun 2016
- 5 [**Cordial** Cordial is a San Diego-based enterprise cross-channel marketing platform founded in 2014.](https://millionrounds.com/company/cordial) Cordial is a San Diego-based enterprise cross-channel marketing platform founded in 2014. *Founded* 2014 San Diego, United States **$71M** last round Jul 2022
- 6 [**Liquid Instruments** Liquid Instruments is a technology company founded in 2014 and based in San Diego, California.](https://millionrounds.com/company/liquid-instruments) Liquid Instruments is a technology company founded in 2014 and based in San Diego, California. *Founded* 2014 San Diego, United States **$58M** last round Apr 2026
- 7 [**ClearNote Health** ClearNote Health is a biotechnology company focused on enhancing early detection and monitoring of high-mortality cancers.](https://millionrounds.com/company/clearnote-health) ClearNote Health is a biotechnology company focused on enhancing early detection and monitoring of high-mortality cancers. *Founded* 2016 San Diego, United States **$52M** last round May 2026
- 8 [**Seasats** Seasats designs and manufactures small uncrewed surface vehicles (sUSVs) designed for monitoring, data collection, and defense applications.](https://millionrounds.com/company/seasats) Seasats designs and manufactures small uncrewed surface vehicles (sUSVs) designed for monitoring, data collection, and defense applications. *Founded* 2020 San Diego, United States **$29M** last round Feb 2026
- 9 [**VIE Technologies** VIE Technologies is a San Diego-based company founded in 2017 that specializes in AI-powered, non-invasive predictive maintenance solutions for critical industr](https://millionrounds.com/company/vie-technologies) VIE Technologies is a San Diego-based company founded in 2017 that specializes in AI-powered, non-invasive predictive maintenance solutions for critical industr *Founded* 2017 San Diego, United States **$15M** last round Mar 2025
- 10 [**Persephone Biosciences** Persephone Biosciences uses artificial intelligence to rapidly develop microbial based immunotherapies to enable a lifetime without cancer.](https://millionrounds.com/company/persephone-biosciences) Persephone Biosciences uses artificial intelligence to rapidly develop microbial based immunotherapies to enable a lifetime without cancer. *Founded* 2017 San Diego, United States **$15M** last round Jul 2022
- 11 [**Self Inspection** Self Inspection is an AI-powered technology company based in San Diego, California, founded in 2021.](https://millionrounds.com/company/self-inspection) Self Inspection is an AI-powered technology company based in San Diego, California, founded in 2021. *Founded* 2021 San Diego, United States **$13M** last round Jul 2026
- 12 [**Ollie AI** Ollie is the world's first Family AI, built to lighten the mental load of parenthood.](https://millionrounds.com/company/ollie-ai) Ollie is the world's first Family AI, built to lighten the mental load of parenthood. *Founded* 2023 San Diego, United States **$7.5M** last round Sept 2026
- 13 [**HelloSky** HelloSky is an AI-powered Agentic Talent Intelligence Platform designed for executive search.](https://millionrounds.com/company/hellosky) HelloSky is an AI-powered Agentic Talent Intelligence Platform designed for executive search. *Founded* 2020 San Diego, United States **$5.5M** last round Apr 2025
- 14 [**XOKind** XOKind is a San Diego-based AI startup founded in 2019, focused on creating AI agents that enhance human planning and decision-making.](https://millionrounds.com/company/xokind) XOKind is a San Diego-based AI startup founded in 2019, focused on creating AI agents that enhance human planning and decision-making. *Founded* 2019 San Diego, United States **$5.3M** last round Dec 2019
- 15 [**Biosynch.ai** Pioneering the future of medicine through artificial intelligence and computational biology.](https://millionrounds.com/company/biosynch-ai) Pioneering the future of medicine through artificial intelligence and computational biology. *Founded* - San Diego, United States **$4.2M** last round Apr 2025
- 16 [**Acurion** Acurion develops AI-driven diagnostic solutions that extract actionable genomic biomarker insights from standard pathology images.](https://millionrounds.com/company/acurion) Acurion develops AI-driven diagnostic solutions that extract actionable genomic biomarker insights from standard pathology images. *Founded* - San Diego, United States **$4.1M** last round Apr 2026
- 17 [**Kantiv** The pursuit intelligence platform for AEC marketing teams](https://millionrounds.com/company/kantiv) The pursuit intelligence platform for AEC marketing teams *Founded* 2022 San Diego, United States **$4.0M** last round Jan 2025
- 18 [**Sinopia Biosciences** Sinopia Biosciences enables data-driven drug discovery by means of multi-omics data, machine learning, network analyses, and disease models.](https://millionrounds.com/company/sinopia-biosciences) Sinopia Biosciences enables data-driven drug discovery by means of multi-omics data, machine learning, network analyses, and disease models. *Founded* 2014 San Diego, United States **$3.6M** last round Jul 2026
- 19 [**Nome Bio** Nome is the Operating System for Personalized TherapiesTM, developing custom treatments for rare disease patients, families, and clinicians.](https://millionrounds.com/company/nome-bio) Nome is the Operating System for Personalized TherapiesTM, developing custom treatments for rare disease patients, families, and clinicians. *Founded* - San Diego, United States **$2.7M** last round Oct 2025
- 20 [**Informuta** Informuta is a biotechnology and infectious disease intelligence company based in San Diego, founded in 2023.](https://millionrounds.com/company/informuta) Informuta is a biotechnology and infectious disease intelligence company based in San Diego, founded in 2023. *Founded* 2023 San Diego, United States **$2.3M** last round Sept 2026
- 21 [**Mirrorva** Mirrorva builds real-time generative AI for video and interactive media.](https://millionrounds.com/company/mirrorva) Mirrorva builds real-time generative AI for video and interactive media. *Founded* - San Diego, United States **$2.0M** last round Sept 2025
- 22 [**lexonlegal** LexonLegal provides AI-powered solutions for contract automation, compliance analysis, and litigation support.](https://millionrounds.com/company/lexonlegal) LexonLegal provides AI-powered solutions for contract automation, compliance analysis, and litigation support. *Founded* - San Diego, United States **$1.2M** last round Sept 2025
- 23 [**Nanome** Nanome is a San Diego-based enterprise software company founded in 2015 by engineering students from the University of California, San Diego.](https://millionrounds.com/company/nanome) Nanome is a San Diego-based enterprise software company founded in 2015 by engineering students from the University of California, San Diego. *Founded* 2015 San Diego, United States **$1.2M** last round Jun 2024
- 24 [**Dynam.AI** Dynam.AI is a San Diego-based software firm specializing in artificial intelligence and machine learning, founded in 2019.](https://millionrounds.com/company/dynam-ai) Dynam.AI is a San Diego-based software firm specializing in artificial intelligence and machine learning, founded in 2019. *Founded* 2019 San Diego, United States **$1.0M** last round Jul 2022
- 25 [**Reliabl** Inclusive content moderation for community platforms.](https://millionrounds.com/company/reliabl) Inclusive content moderation for community platforms. *Founded* 2019 San Diego, United States **$370K** last round Jun 2024
- 26 [**IGNITEIQ** IgniteIQ provides AI transformation and automation services for home services companies in HVAC, plumbing, electrical, and garage doors.](https://millionrounds.com/company/igniteiq) IgniteIQ provides AI transformation and automation services for home services companies in HVAC, plumbing, electrical, and garage doors. *Founded* - San Diego, United States **$350K** last round Sept 2026
- 27 [**AthleteIQ** Athlete IQ connects athletes to the brands and events that celebrate them by helping brands maximize their sponsorship value and ROI at the event level.](https://millionrounds.com/company/athlete-iq) Athlete IQ connects athletes to the brands and events that celebrate them by helping brands maximize their sponsorship value and ROI at the event level. *Founded* 2014 San Diego, United States **$330K** last round Jan 2024
- 28 [**FX1** FX1 is a sports data and technology company that specializes in combat and live sports.](https://millionrounds.com/company/fx1) FX1 is a sports data and technology company that specializes in combat and live sports. *Founded* 2019 San Diego, United States **$250K** last round Aug 2022
- 29 [**Edtera, Inc.** We are an educational and technology company serving the needs of students and educators.](https://millionrounds.com/company/edtera-inc) We are an educational and technology company serving the needs of students and educators. *Founded* 2018 San Diego, United States **$250K** last round Jan 2022
- 30 [**MedlyticsAi** MedlyticsAi is a healthcare AI company based in San Diego, founded in 2020.](https://millionrounds.com/company/medlyticsai) MedlyticsAi is a healthcare AI company based in San Diego, founded in 2020. *Founded* 2020 San Diego, United States **$250K** last round Oct 2021
- 31 [**BWave AI** AI-Powered Enterprise Voice Engine | Automate Your Customer Call Audio Without Human Recording](https://millionrounds.com/company/bwave-ai) AI-Powered Enterprise Voice Engine | Automate Your Customer Call Audio Without Human Recording *Founded* 2023 San Diego, United States **$190K** last round Jul 2025

**Total funding** how the list is ranked

**15 November 2026** updated nightly

**Rounds we track** source: Millionrounds

Companies whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.

## Who backed them?

Open any company for its rounds and investors, or search the investors who back AI startups in San Diego in the app, with filters, lists and exports.

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## More ai lists

[See all](https://millionrounds.com/top-lists?t=AI)

[*O* *A* *X* **AI startups in the United States** 5,656 companies · $718B](https://millionrounds.com/top-lists/ai-startups-united-states)[*O* *A* *B* **AI startups that raised in 2026** 2,922 companies · $540B in 2026](https://millionrounds.com/top-lists/ai-startups-raised-2026)[*MA* *N* *NG* **AI startups in Europe** 2,502 companies · $66B](https://millionrounds.com/top-lists/ai-startups-europe)[*O* *A* *W* **AI startups in the United States that raised in 2026** 1,648 companies · $431B in 2026](https://millionrounds.com/top-lists/ai-startups-united-states-raised-2026)[*O* *D* *TM* **AI startups in San Francisco** 1,276 companies · $321B](https://millionrounds.com/top-lists/ai-startups-san-francisco)[*MA* *MA* *M* **AI startups founded in 2023** 956 companies · $47B](https://millionrounds.com/top-lists/ai-startups-founded-2023)[*H* *IL* *SB* **AI startups founded in 2021** 757 companies · $23B](https://millionrounds.com/top-lists/ai-startups-founded-2021)[*H* *F* *S* **AI startups founded in 2020** 656 companies · $14B](https://millionrounds.com/top-lists/ai-startups-founded-2020)

## More lists for San Diego

[See all](https://millionrounds.com/top-lists?r=San%20Diego)

[*SA* *CT* *AB* **Startups in San Diego** 485 companies · $20B](https://millionrounds.com/top-lists/startups-san-diego)[*CT* *AB* *E* **Biotech startups in San Diego** 154 companies · $9.3B](https://millionrounds.com/top-lists/biotech-startups-san-diego)[*AB* *E* *VT* **Healthcare startups in San Diego** 81 companies · $6.5B](https://millionrounds.com/top-lists/healthcare-startups-san-diego)[*A* *T* *IA* **IT Services startups in San Diego** 39 companies · $396M](https://millionrounds.com/top-lists/it-services-startups-san-diego)[*PT* *ST* *PB* **Pharma startups in San Diego** 22 companies · $904M](https://millionrounds.com/top-lists/pharma-startups-san-diego)[*M* *C* *C* **Big Data & Analytics startups in San Diego** 19 companies · $381M](https://millionrounds.com/top-lists/big-data-startups-san-diego)[*L* *T* *W* **Software startups in San Diego** 14 companies · $811M](https://millionrounds.com/top-lists/software-startups-san-diego)[*AP* *P* *G* **Internet startups in San Diego** 10 companies · $126M](https://millionrounds.com/top-lists/internet-startups-san-diego)