# Top 50 AI Startups Founded in 2021 by Funding (2026)

> The 50 best-funded AI startups founded in 2021, ranked by total funding raised: $23B combined. With founding year, headquarters and each company's rounds.

Source: https://millionrounds.com/top-lists/ai-startups-founded-2021 (Millionrounds; every figure on the page links to its filing or article)

- 1 [**Helsing** Helsing is a German defense technology company based in Munich, founded in 2021.](https://millionrounds.com/company/helsing) Helsing is a German defense technology company based in Munich, founded in 2021. *Founded* 2021 Munich, Germany **$3.7B** last round Jul 2026
- 2 [**Isomorphic Labs** Isomorphic Labs is a London-based artificial intelligence company focused on transforming the drug discovery process.](https://millionrounds.com/company/isomorphic-labs) Isomorphic Labs is a London-based artificial intelligence company focused on transforming the drug discovery process. *Founded* 2021 London, United Kingdom **$3.1B** last round May 2026
- 3 [**Silicon Box** SILICON BOX is a Singapore-based company specializing in advanced semiconductor packaging and chiplet integration.](https://millionrounds.com/company/silicon-box) SILICON BOX is a Singapore-based company specializing in advanced semiconductor packaging and chiplet integration. *Founded* 2021 Singapore, Singapore **$1.4B** last round Jun 2026
- 4 [**MiniMax** MiniMax develops AI technology for social connections and interaction, converting text into visual, audio, and text to text modes.](https://millionrounds.com/company/minimax) MiniMax develops AI technology for social connections and interaction, converting text into visual, audio, and text to text modes. *Founded* 2021 Austin, Singapore **$1.2B** last round Jul 2026
- 5 [**Retro Biosciences** Retro Biosciences is a biotechnology company based in Redwood City, California, founded in May 2021.](https://millionrounds.com/company/retro-biosciences) Retro Biosciences is a biotechnology company based in Redwood City, California, founded in May 2021. *Founded* 2021 Redwood City, United States **$1.2B** last round May 2026
- 6 [**Waabi** Waabi is an artificial intelligence company based in Toronto, Canada, specializing in autonomous self-driving technology for long-haul trucking.](https://millionrounds.com/company/waabi) Waabi is an artificial intelligence company based in Toronto, Canada, specializing in autonomous self-driving technology for long-haul trucking. *Founded* 2021 Toronto, Canada **$1.0B** last round Jan 2026
- 7 [**Luma AI** Luma AI is a generative AI startup that enables users to transform text descriptions into corresponding 3D models.](https://millionrounds.com/company/luma-ai) Luma AI is a generative AI startup that enables users to transform text descriptions into corresponding 3D models. *Founded* 2021 Redwood City, United States **$900M** last round Nov 2025
- 8 [**OpenEvidence** OpenEvidence is an AI-powered medical information platform and clinical decision support tool designed for healthcare professionals.](https://millionrounds.com/company/openevidence) OpenEvidence is an AI-powered medical information platform and clinical decision support tool designed for healthcare professionals. *Founded* 2021 Miami, United States **$775M** last round Sept 2026
- 9 [**Function Health** 100 Healthy Years • Your new routine of 120+ advanced lab tests explained by the world's top doctors](https://millionrounds.com/company/function-health) 100 Healthy Years • Your new routine of 120+ advanced lab tests explained by the world's top doctors *Founded* 2021 Austin, United States **$748M** last round Jul 2026
- 10 [**Bitdeer Technologies Group** Bitdeer is a provider of digital asset mining services for blockchain and high-performance computing.](https://millionrounds.com/company/bitdeer-technologies-group) Bitdeer is a provider of digital asset mining services for blockchain and high-performance computing. *Founded* 2021 Singapore, Singapore **$725M** last round Feb 2026
- 11 [**1KOMMA5°** 1Komma5° is an electricity company offering free electricity to all electric vehicle owners financed through trading using GHG quotas.](https://millionrounds.com/company/1komma5) 1Komma5° is an electricity company offering free electricity to all electric vehicle owners financed through trading using GHG quotas. *Founded* 2021 Hamburg, Germany **$563M** last round Oct 2026
- 12 [**TeraWulf** TeraWulf is a bitcoin mining company that produces zero-carbon energy for crypto mining.](https://millionrounds.com/company/terawulf) TeraWulf is a bitcoin mining company that produces zero-carbon energy for crypto mining. *Founded* 2021 Easton, United States **$500M** last round Oct 2025
- 13 [**Modal Labs** Modal develops machine learning software to help run code in the cloud.](https://millionrounds.com/company/modal-labs) Modal develops machine learning software to help run code in the cloud. *Founded* 2021 New York, United States **$442M** last round Jun 2026
- 14 [**Whop** Whop is a social commerce platform and online marketplace based in Brooklyn, New York.](https://millionrounds.com/company/whop) Whop is a social commerce platform and online marketplace based in Brooklyn, New York. *Founded* 2021 New York, United States **$400M** last round Oct 2026
- 15 [**Panthalassa** Panthalassa is a public-benefit corporation based in Portland, Oregon, founded in 2016.](https://millionrounds.com/company/panthalassa) Panthalassa is a public-benefit corporation based in Portland, Oregon, founded in 2016. *Founded* 2021 Portland, United States **$365M** last round Aug 2026
- 16 [**Antimatter** Antimatter is a data security company that provides cryptographic infrastructure services to B2B SaaS companies.](https://millionrounds.com/company/antimatter) Antimatter is a data security company that provides cryptographic infrastructure services to B2B SaaS companies. *Founded* 2021 Ottawa, Canada **$363M** last round May 2026
- 17 [**Serve Robotics** Serve Robotics develops self-driving robots to deliver food and supplies.](https://millionrounds.com/company/serve-robotics) Serve Robotics develops self-driving robots to deliver food and supplies. *Founded* 2021 Redwood City, United States **$330M** last round May 2026
- 18 [**Nitra** Nitra is overhauling the healthcare industry with radically efficient and transparent solutions - starting with spend management.](https://millionrounds.com/company/nitra) Nitra is overhauling the healthcare industry with radically efficient and transparent solutions - starting with spend management. *Founded* 2021 New York, United States **$302M** last round Mar 2026
- 19 [**Ledgebrook** Ledgebrook is a technology-enabled Managing General Agent (MGA) based in Boston, Massachusetts, specializing in Excess and Surplus (E&S) lines of insurance.](https://millionrounds.com/company/ledgebrook) Ledgebrook is a technology-enabled Managing General Agent (MGA) based in Boston, Massachusetts, specializing in Excess and Surplus (E&S) lines of insurance. *Founded* 2021 Needham, United States **$265M** last round Oct 2026
- 20 [**Covenant** Covenant is an innovative AI law firm focused on serving private market investors.](https://millionrounds.com/company/covenant) Covenant is an innovative AI law firm focused on serving private market investors. *Founded* 2021 New York, United States **$254M** last round Sept 2026
- 21 [**Slide Insurance** SlideCompany is a technology-enabled insurance provider that uses AI and big data to deliver home insurance coverage to consumers.](https://millionrounds.com/company/slide-insurance) SlideCompany is a technology-enabled insurance provider that uses AI and big data to deliver home insurance coverage to consumers. *Founded* 2021 Tampa, United States **$250M** last round May 2025
- 22 [**Tebra** Tebra Technologies, Inc.](https://millionrounds.com/company/tebra) Tebra Technologies, Inc. *Founded* 2021 Newport Beach, United States **$250M** last round Jan 2026
- 23 [**Axelera AI** Axelera AI is a European AI semiconductor company based in Eindhoven, Netherlands.](https://millionrounds.com/company/axelera-ai) Axelera AI is a European AI semiconductor company based in Eindhoven, Netherlands. *Founded* 2021 Eindhoven, Netherlands **$250M** last round Feb 2026
- 24 [**Rivos** Rivos is a high-performance RISC-V system startup targeting integrated system solutions for enterprises.](https://millionrounds.com/company/rivos) Rivos is a high-performance RISC-V system startup targeting integrated system solutions for enterprises. *Founded* 2021 Santa Clara, United States **$250M** last round Aug 2025
- 25 [**Yendo** Yendo issues credit cards secured by customer vehicle equity for lending.](https://millionrounds.com/company/yendo) Yendo issues credit cards secured by customer vehicle equity for lending. *Founded* 2021 Dallas, United States **$250M** last round Feb 2026
- 26 [**Science Corp**](https://millionrounds.com/company/science-corp) *Founded* 2021 United States **$230M** last round Mar 2026
- 27 [**Relay** Relay is a workflow automation tool with a human touch.](https://millionrounds.com/company/relay) Relay is a workflow automation tool with a human touch. *Founded* 2021 San Francisco, United States **$207M** last round Oct 2026
- 28 [**Eliyan** Eliyan manufactures semiconductor interconnects to accelerate chiplet-based systems.](https://millionrounds.com/company/eliyan) Eliyan manufactures semiconductor interconnects to accelerate chiplet-based systems. *Founded* 2021 Santa Clara, United States **$195M** last round Jul 2026
- 29 [**Rillet** Rillet is an AI-native accounting and ERP platform founded in 2021, designed to automate core finance workflows for SaaS, usage-based, high-growth, and public companies.](https://millionrounds.com/company/rillet) Rillet is an AI-native accounting and ERP platform founded in 2021, designed to automate core finance workflows for SaaS, usage-based, high-growth, and public companies. *Founded* 2021 San Francisco, United States **$195M** last round Aug 2026
- 30 [**Savvy Wealth** Savvy Wealth is a technology-enabled wealth management firm.](https://millionrounds.com/company/savvy-wealth) Savvy Wealth is a technology-enabled wealth management firm. *Founded* 2021 New York, United States **$188M** last round Sept 2026
- 31 [**Nourish** Nourish connects people with a Registered Dietitian via telehealth and gets it covered by their health insurance.](https://millionrounds.com/company/nourish) Nourish connects people with a Registered Dietitian via telehealth and gets it covered by their health insurance. *Founded* 2021 New York, United Kingdom **$173M** last round May 2026
- 32 [**Exa** Exa is an applied AI research lab based in San Francisco, founded in 2021.](https://millionrounds.com/company/exa) Exa is an applied AI research lab based in San Francisco, founded in 2021. *Founded* 2021 San Francisco, United States **$170M** last round May 2026
- 33 [**Enigma** We are an open platform with blockchain-based technology and simple tools for artists and creators to grow alongside fans, investors and the entertainment indus](https://millionrounds.com/company/enigma) We are an open platform with blockchain-based technology and simple tools for artists and creators to grow alongside fans, investors and the entertainment indus *Founded* 2021 Saint Petersburg, United States **$166M** last round Jul 2026
- 34 [**Shop Circle** Shop Circle is a technology company that acquires and grows e-commerce software.](https://millionrounds.com/company/shop-circle) Shop Circle is a technology company that acquires and grows e-commerce software. *Founded* 2021 London, Italy **$160M** last round Sept 2025
- 35 [**CHARM Therapeutics** CHARM Therapeutics is a London-based biotechnology company founded in 2021.](https://millionrounds.com/company/charm-therapeutics) CHARM Therapeutics is a London-based biotechnology company founded in 2021. *Founded* 2021 London, United Kingdom **$149M** last round Sept 2025
- 36 [**LiveKit** LiveKit offers open source frameworks and a cloud platform for building voice, video, and physical AI agents.](https://millionrounds.com/company/livekit) LiveKit offers open source frameworks and a cloud platform for building voice, video, and physical AI agents. *Founded* 2021 San Francisco, United States **$145M** last round Jan 2026
- 37 [**Sereact** Sereact is a technology company based in Stuttgart, Germany, founded in 2021.](https://millionrounds.com/company/sereact) Sereact is a technology company based in Stuttgart, Germany, founded in 2021. *Founded* 2021 Stuttgart, Germany **$136M** last round Apr 2026
- 38 [**Loop** LOOP provides an e-commerce platform for online sales and payment processing.](https://millionrounds.com/company/loop) LOOP provides an e-commerce platform for online sales and payment processing. *Founded* 2021 United States **$133M** last round Apr 2026
- 39 [**Convex** Convex is a San Francisco-based company that offers an open-source reactive backend platform designed for web developers.](https://millionrounds.com/company/convex) Convex is a San Francisco-based company that offers an open-source reactive backend platform designed for web developers. *Founded* 2021 San Francisco, United States **$120M** last round Aug 2026
- 40 [**Stepful** Stepful is an AI-powered online training and job placement platform founded in 2021, headquartered in New York, NY, with a corporate office in Detroit, MI.](https://millionrounds.com/company/stepful) Stepful is an AI-powered online training and job placement platform founded in 2021, headquartered in New York, NY, with a corporate office in Detroit, MI. *Founded* 2021 New York, United States **$118M** last round Jun 2026
- 41 [**Miter** Simple, powerful HR + finance software for contractors.](https://millionrounds.com/company/miter) Simple, powerful HR + finance software for contractors. *Founded* 2021 San Francisco, United States **$113M** last round Sept 2026
- 42 [**LayerX** LayerX is a provider of a browser security platform that turns any browser into a secure and manageable workspace.](https://millionrounds.com/company/layerx) LayerX is a provider of a browser security platform that turns any browser into a secure and manageable workspace. *Founded* 2021 Japan **$111M** last round Sept 2025
- 43 [**Tutor Intelligence** Tutor Intelligence is an information technology company that specializes in the fields of robotics, AI, and machine learning.](https://millionrounds.com/company/tutor-intelligence) Tutor Intelligence is an information technology company that specializes in the fields of robotics, AI, and machine learning. *Founded* 2021 Watertown, United States **$109M** last round Nov 2026
- 44 [**Lawhive** Lawhive is a technology-driven consultancy-based law firm based in the United Kingdom.](https://millionrounds.com/company/lawhive) Lawhive is a technology-driven consultancy-based law firm based in the United Kingdom. *Founded* 2021 London, United Kingdom **$107M** last round Feb 2026
- 45 [**lark** Lark is a producer and retailer of CBD, CBG, and CBC sparkling water.](https://millionrounds.com/company/lark) Lark is a producer and retailer of CBD, CBG, and CBC sparkling water. *Founded* 2021 New Albany, United States **$105M** last round Sept 2025
- 46 [**Swap Commerce**](https://millionrounds.com/company/swap-commerce) *Founded* 2021 United Kingdom **$103M** last round Jan 2026
- 47 [**Stream** Stream is an order and menu management solution made simple for restaurants, POS brands, and delivery providers.](https://millionrounds.com/company/stream) Stream is an order and menu management solution made simple for restaurants, POS brands, and delivery providers. *Founded* 2021 Saudi Arabia **$101M** last round Jan 2026
- 48 [**Trajectory** Trajectory is a civil engineering company that offers transport development and railway engineering services.](https://millionrounds.com/company/trajectory) Trajectory is a civil engineering company that offers transport development and railway engineering services. *Founded* 2021 United States **$101M** last round Nov 2026
- 49 [**Gynger** The first AI-powered payments platform with embedded financing, built for buyers and sellers of technology.](https://millionrounds.com/company/gynger) The first AI-powered payments platform with embedded financing, built for buyers and sellers of technology. *Founded* 2021 New York, United States **$100M** last round Jun 2024
- 50 [**Hydra Host** Hydra Host is a Miami-based technology company founded in 2021.](https://millionrounds.com/company/hydra-host) Hydra Host is a Miami-based technology company founded in 2021. *Founded* 2021 Miami, United States **$100M** last round Jun 2026

**Total funding** how the list is ranked

**15 November 2026** updated nightly

**Rounds we track** source: Millionrounds

Companies founded in 2021 whose funding rounds we classed in this sector, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.

## Who backed them?

Open any company for its rounds and investors, or search the investors who back AI startups founded in 2021 in the app, with filters, lists and exports.

[Find their investors](https://millionrounds.com/login?join=1&next=/app/investors)[All top lists](https://millionrounds.com/top-lists)

## More ai lists

[See all](https://millionrounds.com/top-lists?t=AI)

[*O* *A* *X* **AI startups in the United States** 5,656 companies · $718B](https://millionrounds.com/top-lists/ai-startups-united-states)[*O* *A* *B* **AI startups that raised in 2026** 2,922 companies · $540B in 2026](https://millionrounds.com/top-lists/ai-startups-raised-2026)[*MA* *N* *NG* **AI startups in Europe** 2,502 companies · $66B](https://millionrounds.com/top-lists/ai-startups-europe)[*O* *A* *W* **AI startups in the United States that raised in 2026** 1,648 companies · $431B in 2026](https://millionrounds.com/top-lists/ai-startups-united-states-raised-2026)[*O* *D* *TM* **AI startups in San Francisco** 1,276 companies · $321B](https://millionrounds.com/top-lists/ai-startups-san-francisco)[*MA* *MA* *M* **AI startups founded in 2023** 956 companies · $47B](https://millionrounds.com/top-lists/ai-startups-founded-2023)[*H* *F* *S* **AI startups founded in 2020** 656 companies · $14B](https://millionrounds.com/top-lists/ai-startups-founded-2020)[*FT* *P* *C* **AI startups founded in 2019** 652 companies · $51B](https://millionrounds.com/top-lists/ai-startups-founded-2019)

## More lists worldwide

[See all](https://millionrounds.com/top-lists?r=Global)

[*GV* *V* *RP* **Health startups worldwide** 12,811 companies · $81B](https://millionrounds.com/top-lists/health-startups)[*O* *A* *X* **AI startups worldwide** 10,238 companies · $830B](https://millionrounds.com/top-lists/ai-startups)[*GV* *V* *RP* **Biotech startups worldwide** 7,127 companies · $70B](https://millionrounds.com/top-lists/biotech-startups)[*D* *B* *FT* **Big data startups worldwide** 3,812 companies · $220B](https://millionrounds.com/top-lists/big-data-startups)[*AF* *R* *S* **Fintech startups worldwide** 3,200 companies · $94B](https://millionrounds.com/top-lists/fintech-startups)[*FT* *CE* *P* **Energy providers startups worldwide** 2,808 companies · $152B](https://millionrounds.com/top-lists/energy-providers-startups)[*A* *P* *O* **Marketing tech startups worldwide** 2,728 companies · $28B](https://millionrounds.com/top-lists/marketing-tech-startups)[*SA* *C* *D* **Customer service startups worldwide** 2,637 companies · $64B](https://millionrounds.com/top-lists/customer-service-startups)