# Top 45 AI Startups in Chicago by Funding (2026)

> The 45 best-funded AI startups in Chicago, ranked by total funding raised: $912M combined. With founding year, headquarters and each company's rounds.

Source: https://millionrounds.com/top-lists/ai-startups-chicago (Millionrounds; every figure on the page links to its filing or article)

- 1 [**Ocient** Ocient is a data analytics software solutions company based in Chicago, Illinois, founded in 2016.](https://millionrounds.com/company/ocient) Ocient is a data analytics software solutions company based in Chicago, Illinois, founded in 2016. *Founded* 2016 Chicago, United States **$200M** last round Nov 2026
- 2 [**Chowbus** Chowbus is a full-stack restaurant technology company and food delivery platform based in Chicago, Illinois.](https://millionrounds.com/company/chowbus) Chowbus is a full-stack restaurant technology company and food delivery platform based in Chicago, Illinois. *Founded* 2016 Chicago, United States **$105M** last round Mar 2026
- 3 [**Evozyne** Evozyne is a biotechnology company based in Chicago, Illinois, focused on designing and developing innovative protein therapeutics and synthetic proteins.](https://millionrounds.com/company/evozyne) Evozyne is a biotechnology company based in Chicago, Illinois, focused on designing and developing innovative protein therapeutics and synthetic proteins. *Founded* 2020 Chicago, United States **$81M** last round Sept 2023
- 4 [**HealthJoy** HealthJoy is a healthcare technology company based in Chicago, founded in 2014.](https://millionrounds.com/company/healthjoy) HealthJoy is a healthcare technology company based in Chicago, founded in 2014. *Founded* 2014 Chicago, United States **$73M** last round Oct 2022
- 5 [**Threekit** Threekit is an AI-powered Visual Commerce Platform based in Chicago, Illinois.](https://millionrounds.com/company/threekit) Threekit is an AI-powered Visual Commerce Platform based in Chicago, Illinois. *Founded* 2018 Chicago, United States **$65M** last round Nov 2021
- 6 [**Narrative Science** Narrative Science creates software that writes stories from enterprise data to drive understanding and results.](https://millionrounds.com/company/narrative-science) Narrative Science creates software that writes stories from enterprise data to drive understanding and results. *Founded* 2010 Chicago, United States **$49M** last round Apr 2017
- 7 [**Letter AI** Letter AI is an innovative revenue enablement platform founded in 2023 by Ali Akhtar and Armen Forget, based in Chicago, Illinois.](https://millionrounds.com/company/letter-ai) Letter AI is an innovative revenue enablement platform founded in 2023 by Ali Akhtar and Armen Forget, based in Chicago, Illinois. *Founded* 2023 Chicago, United States **$43M** last round Feb 2026
- 8 [**Empirical Security** Empirical builds mathematical models for security data.](https://millionrounds.com/company/empirical-security) Empirical builds mathematical models for security data. *Founded* 2024 Chicago, United States **$37M** last round Jul 2026
- 9 [**Hugo Technologies** Hugo Technologies offers outsourcing for customer support, e-commerce management, fraud prevention, and AI data processing.](https://millionrounds.com/company/hugo-technologies) Hugo Technologies offers outsourcing for customer support, e-commerce management, fraud prevention, and AI data processing. *Founded* - Chicago, United States **$30M** last round Jan 2026
- 10 [**PatientIQ** PatientIQ is a healthcare technology company based in Chicago, founded in 2016.](https://millionrounds.com/company/patientiq) PatientIQ is a healthcare technology company based in Chicago, founded in 2016. *Founded* 2016 Chicago, United States **$30M** last round Sept 2026
- 11 [**KeyCare** KeyCare is a virtual care platform that enhances telehealth solutions for health systems using Epic's infrastructure.](https://millionrounds.com/company/keycare) KeyCare is a virtual care platform that enhances telehealth solutions for health systems using Epic's infrastructure. *Founded* 2022 Chicago, United States **$29M** last round Sept 2026
- 12 [**Prenosis** Prenosis Inc.](https://millionrounds.com/company/prenosis) Prenosis Inc. *Founded* 2014 Chicago, United States **$20M** last round Jan 2026
- 13 [**Waltz Health** Waltz Health is a new digital health company.](https://millionrounds.com/company/waltz-health) Waltz Health is a new digital health company. *Founded* 2021 Chicago, United States **$18M** last round Nov 2024
- 14 [**Nucleai** Nucleai is an AI-powered spatial biology software platform focused on precision medicine.](https://millionrounds.com/company/nucleai) Nucleai is an AI-powered spatial biology software platform focused on precision medicine. *Founded* 2018 Chicago, United States **$14M** last round Apr 2024
- 15 [**Laconic Infrastructure Partners** Laconic Infrastructure Partners specializes in providing integrated environmental intelligence services.](https://millionrounds.com/company/laconic-infrastructure-partners) Laconic Infrastructure Partners specializes in providing integrated environmental intelligence services. *Founded* 2019 Chicago, United States **$12M** last round Jun 2023
- 16 [**Stately Bio** Stately Bio is a biotechnology company based in Palo Alto, founded in 2022.](https://millionrounds.com/company/stately-bio) Stately Bio is a biotechnology company based in Palo Alto, founded in 2022. *Founded* - Chicago, United States **$12M** last round May 2025
- 17 [**Newity** NEWITY, based in Chicago, is a fintech company founded in 2020.](https://millionrounds.com/company/newity) NEWITY, based in Chicago, is a fintech company founded in 2020. *Founded* 2021 Chicago, United States **$11M** last round Feb 2026
- 18 [**StitchStudio** StitchStudio is an AI platform tailored for the insurance industry, aimed at helping carriers, brokers, managing general agents (MGAs), and third-party administ](https://millionrounds.com/company/stitchstudio) StitchStudio is an AI platform tailored for the insurance industry, aimed at helping carriers, brokers, managing general agents (MGAs), and third-party administ *Founded* - Chicago, United States **$8.0M** last round Nov 2026
- 19 [**Technical Paradigm** Technical Paradigm is an IT staffing and recruiting agency based in Chicago, specializing in connecting businesses with qualified IT professionals.](https://millionrounds.com/company/technical-paradigm) Technical Paradigm is an IT staffing and recruiting agency based in Chicago, specializing in connecting businesses with qualified IT professionals. *Founded* 2016 Chicago, United States **$7.5M** last round Aug 2023
- 20 [**Qumis** Qumis is an AI-powered knowledge platform for complex risks.](https://millionrounds.com/company/qumis) Qumis is an AI-powered knowledge platform for complex risks. *Founded* 2022 Chicago, United States **$6.5M** last round Feb 2026
- 21 [**Yourco** Yourco is a B2B SaaS company based in Indianapolis, Indiana, founded in 2021.](https://millionrounds.com/company/yourco) Yourco is a B2B SaaS company based in Indianapolis, Indiana, founded in 2021. *Founded* 2021 Chicago, United States **$6.0M** last round Mar 2026
- 22 [**iAsk Ai** iAsk.Ai is an AI-powered answer engine founded in 2022 and based in Chicago, Illinois.](https://millionrounds.com/company/iask-ai) iAsk.Ai is an AI-powered answer engine founded in 2022 and based in Chicago, Illinois. *Founded* 2013 Chicago, United States **$5.7M** last round Feb 2024
- 23 [**Sibel Health** Sibel Health, Inc.](https://millionrounds.com/company/sibel-health) Sibel Health, Inc. *Founded* 2018 Chicago, United States **$5.5M** last round Apr 2026
- 24 [**SAVVI AI** Savvi AI is a low-code, enterprise-grade AI platform founded in 2021 and based in Chicago, Illinois.](https://millionrounds.com/company/savvi-ai) Savvi AI is a low-code, enterprise-grade AI platform founded in 2021 and based in Chicago, Illinois. *Founded* 2021 Chicago, United States **$5.5M** last round Sept 2023
- 25 [**Monda** Monda is a B2B SaaS data monetization platform founded in 2024 and headquartered in Dover, Delaware, with additional locations in Berlin and Chicago.](https://millionrounds.com/company/monda) Monda is a B2B SaaS data monetization platform founded in 2024 and headquartered in Dover, Delaware, with additional locations in Berlin and Chicago. *Founded* 2024 Chicago, United States **$5.0M** last round Sept 2024
- 26 [**Clearstep** Clinical-grade A.I.](https://millionrounds.com/company/clearstep) Clinical-grade A.I. *Founded* 2018 Chicago, United States **$4.2M** last round Jan 2025
- 27 [**Arvist** Arvist is a logistics technology company based in Chicago, founded in 2021.](https://millionrounds.com/company/arvist) Arvist is a logistics technology company based in Chicago, founded in 2021. *Founded* 2022 Chicago, United States **$4.0M** last round Sept 2025
- 28 [**Responsiv** Responsiv is a legal technology company based in Chicago, founded in 2023.](https://millionrounds.com/company/responsiv) Responsiv is a legal technology company based in Chicago, founded in 2023. *Founded* 2023 Chicago, United States **$3.0M** last round Nov 2023
- 29 [**Classet** Classet is a Chicago-based AI-powered recruiting platform that simplifies the hiring process for skilled trades and blue-collar workers across the United States.](https://millionrounds.com/company/classet) Classet is a Chicago-based AI-powered recruiting platform that simplifies the hiring process for skilled trades and blue-collar workers across the United States. *Founded* 2021 Chicago, United States **$3.0M** last round Dec 2022
- 30 [**Mahalo** Mahalo is an AI-powered post-purchase experience platform designed to help manufacturers with warranty management and customer interactions.](https://millionrounds.com/company/mahalo) Mahalo is an AI-powered post-purchase experience platform designed to help manufacturers with warranty management and customer interactions. *Founded* - Chicago, United States **$2.6M** last round Jun 2025
- 31 [**SafeHill** SafeHill is an AI-powered cybersecurity SaaS company based in Chicago, Illinois, specializing in Continuous Threat Exposure Management (CTEM).](https://millionrounds.com/company/safehill) SafeHill is an AI-powered cybersecurity SaaS company based in Chicago, Illinois, specializing in Continuous Threat Exposure Management (CTEM). *Founded* 2025 Chicago, United States **$2.6M** last round Sept 2025
- 32 [**Nimblemind.ai** Nimblemind.ai is a healthcare technology company based in Chicago, founded in 2024.](https://millionrounds.com/company/nimblemind-ai) Nimblemind.ai is a healthcare technology company based in Chicago, founded in 2024. *Founded* 2024 Chicago, United States **$2.5M** last round Mar 2025
- 33 [**Heretik** Heretik is a legal technology company based in Chicago, founded in 2016.](https://millionrounds.com/company/heretik) Heretik is a legal technology company based in Chicago, founded in 2016. *Founded* 2016 Chicago, United States **$2.4M** last round Jan 2020
- 34 [**Force Equals** Force Equals is a startup based in Tampa, Florida, founded in 2025.](https://millionrounds.com/company/force-equals) Force Equals is a startup based in Tampa, Florida, founded in 2025. *Founded* 2024 Chicago, United States **$2.2M** last round Feb 2026
- 35 [**The Collaboratory** The Collaboratory is a Chicago-based AI company founded in 2020.](https://millionrounds.com/company/the-collaboratory) The Collaboratory is a Chicago-based AI company founded in 2020. *Founded* 2020 Chicago, United States **$1.6M** last round Apr 2022
- 36 [**Brighthive** Brighthive is a Chicago-based AI startup founded in 2018 that offers an agentic data operations (DataOps) platform.](https://millionrounds.com/company/brighthive) Brighthive is a Chicago-based AI startup founded in 2018 that offers an agentic data operations (DataOps) platform. *Founded* 2021 Chicago, United States **$1.3M** last round Jul 2019
- 37 [**ConceptDrop** ConceptDrop matches brands with an invite-only community of creative professionals.](https://millionrounds.com/company/conceptdrop) ConceptDrop matches brands with an invite-only community of creative professionals. *Founded* 2012 Chicago, United States **$1.3M** last round May 2016
- 38 [**RepIQ** Free email tracking for Gmail.](https://millionrounds.com/company/repiq) Free email tracking for Gmail. *Founded* 2016 Chicago, United States **$1.1M** last round Jul 2017
- 39 [**DigsFact** DigsFact is an AI-driven software company based in Crystal Lake, Illinois, founded in 2018.](https://millionrounds.com/company/digsfact) DigsFact is an AI-driven software company based in Crystal Lake, Illinois, founded in 2018. *Founded* 2018 Chicago, United States **$1.0M** last round Mar 2024
- 40 [**Blip Energy** Blip is building a drop-in distributed energy resource to mitigate surging demand, optimize user costs and reduce utility operating costs.](https://millionrounds.com/company/blip-energy) Blip is building a drop-in distributed energy resource to mitigate surging demand, optimize user costs and reduce utility operating costs. *Founded* - Chicago, United States **$500K** last round Nov 2024
- 41 [**GLCTC Corp** GLCTC Corp is a technology company that focuses on creating the next generation of software and hardware.](https://millionrounds.com/company/glctc-corp) GLCTC Corp is a technology company that focuses on creating the next generation of software and hardware. *Founded* 2018 Chicago, United States **$300K** last round Jun 2024
- 42 [**Verboso** Verboso develops an open-source database of impaired speech sounds for children.](https://millionrounds.com/company/verboso) Verboso develops an open-source database of impaired speech sounds for children. *Founded* 2018 Chicago, United States **$250K** last round Aug 2021
- 43 [**TRaiCE** TRaiCE is an AI-based early warning business risk detection and monitoring system for lenders and investors.](https://millionrounds.com/company/traice) TRaiCE is an AI-based early warning business risk detection and monitoring system for lenders and investors. *Founded* 2021 Chicago, United States **$200K** last round Dec 2023
- 44 [**Iris Light Technologies** Iris Light Technologies is a Chicago-based company specializing in nanotechnology and silicon photonics.](https://millionrounds.com/company/iris-light-technologies) Iris Light Technologies is a Chicago-based company specializing in nanotechnology and silicon photonics. *Founded* 2018 Chicago, United States **$120K** last round Sept 2023
- 45 [**SupplyHive** SupplyHiveTM is a Chicago-based enterprise software company founded in 2018, specializing in Supplier Performance Management (SPM) and Supplier Relationship Man](https://millionrounds.com/company/supplyhive) SupplyHiveTM is a Chicago-based enterprise software company founded in 2018, specializing in Supplier Performance Management (SPM) and Supplier Relationship Man *Founded* 2018 Chicago, United States **$10K** last round Dec 2022

**Total funding** how the list is ranked

**15 November 2026** updated nightly

**Rounds we track** source: Millionrounds

Companies whose funding rounds we classed as any of these sectors, ranked by the total they have raised in rounds we hold. Nobody pays to be on a list.

## Who backed them?

Open any company for its rounds and investors, or search the investors who back AI startups in Chicago in the app, with filters, lists and exports.

[Find their investors](https://millionrounds.com/login?join=1&next=/app/investors)[All top lists](https://millionrounds.com/top-lists)

## More artificial intelligence lists

[See all](https://millionrounds.com/top-lists?t=Artificial%20intelligence)

[*O* *D* *W* **AI startups in Bay Area** 1,959 companies · $375B](https://millionrounds.com/top-lists/ai-startups-bay-area)[*F* *VD* *P* **AI startups in New York** 702 companies · $19B](https://millionrounds.com/top-lists/ai-startups-new-york)[*IL* *W* *U* **AI startups in London** 479 companies · $18B](https://millionrounds.com/top-lists/ai-startups-london)[*R* *S* *D* **AI startups in Boston** 197 companies · $12B](https://millionrounds.com/top-lists/ai-startups-boston)[*VA* *F* *S* **AI startups in Los Angeles** 182 companies · $7.8B](https://millionrounds.com/top-lists/ai-startups-los-angeles)[*MA* *M* *P* **AI startups in Paris** 159 companies · $14B](https://millionrounds.com/top-lists/ai-startups-paris)[*S* *O* *H* **AI startups in Seattle** 150 companies · $3.1B](https://millionrounds.com/top-lists/ai-startups-seattle)[*PL* *P* *S* **AI startups in Berlin** 111 companies · $3.7B](https://millionrounds.com/top-lists/ai-startups-berlin)

## More lists for Chicago

[See all](https://millionrounds.com/top-lists?r=Chicago)

[*V* *OH* *O* **Startups in Chicago** 617 companies · $16B](https://millionrounds.com/top-lists/startups-chicago)[*V* *OH* *NF* **Health startups in Chicago** 86 companies · $9.6B](https://millionrounds.com/top-lists/health-startups-chicago)[*V* *OH* *OS* **Healthcare startups in Chicago** 62 companies · $8.7B](https://millionrounds.com/top-lists/healthcare-startups-chicago)[*N* *R* *S* **IT Services startups in Chicago** 48 companies · $948M](https://millionrounds.com/top-lists/it-services-startups-chicago)[*V* *OH* *NF* **Biotech startups in Chicago** 34 companies · $8.5B](https://millionrounds.com/top-lists/biotech-startups-chicago)[*O* *P* *CA* **Big Data & Analytics startups in Chicago** 32 companies · $771M](https://millionrounds.com/top-lists/big-data-startups-chicago)[*D* *T* *LO* **Advertising & Adtech startups in Chicago** 30 companies · $320M](https://millionrounds.com/top-lists/adtech-startups-chicago)[*SA* *A* *S* **Software startups in Chicago** 28 companies · $845M](https://millionrounds.com/top-lists/software-startups-chicago)