# Genespire: Research, Milan, Italy

> Genespire: Genespire is a biotechnology company based in Milan, Italy, focused on developing innovative gene therapies for severe genetic diseases.

Source: https://millionrounds.com/startup/genespire (Millionrounds; every figure on the page links to its filing or article)

Italy · [Research startup](https://millionrounds.com/companies)

# Genespire

Genespire is a biotechnology company based in Milan, Italy, focused on developing innovative gene therapies for severe genetic diseases.

Email

Funding reported Last round: Series A

Research Milan, Italy

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Company summary

- **Founded:** 2020 6 years old
- **Team:** 17 11 to 50 people
- **Funding reported:** 52.2M as listed, currency not stated
- **Last round:** Series A Apr 2020

How sure we are

- ✓ **Listed** We know it exists and what it does
- 2 **Funding reported** A company dataset reports a raise
- 3 **Observed** A filing or a dated announcement confirms a round

No round for Genespire has been confirmed by a filing or an announcement yet, so nothing here counts toward an investor's record. [How we decide](https://millionrounds.com/methodology)

## About Genespire

Genespire is a biotechnology company based in Milan, Italy, focused on developing innovative gene therapies for severe genetic diseases.

Founded in March 2020 as a spin-out from the San Raffaele Telethon Institute for Gene Therapy, Genespire aims to create "off-the-shelf" therapies that can be administered directly into a patient's bloodstream. This approach simplifies treatment by eliminating the need for complex cell extraction and re-infusion procedures. The company utilizes its proprietary Immune Shielded Lentiviral Vectors (ISLVs) to deliver therapeutic genes directly to the liver, ensuring long-term expression and benefits for patients. Genespire is currently advancing its lead candidate, GENE202, targeting methylmalonic acidaemia, with plans to initiate clinical trials by the end of 2026. The company is dedicated to addressing high unmet medical needs in inherited metabolic diseases and primary immunodeficiencies, making gene therapy more accessible for both pediatric and adult patients.

## What company datasets say Genespire raised

Funding, as reported

Reported in all **52.2M** in the source's currency

Rounds **1**

Last round **Series A**

Last round size **51.3M**

Last round date **Apr 2020**

Investors listed **4**

## On 2 portfolio pages

Investors who name them

- [XGEN Venture](https://millionrounds.com/fund/xgen-venture)
- [CDP Venture Capital](https://millionrounds.com/fund/cdp-venture-capital)

Each firm lists Genespire on its own website. That is the firm's claim, a weaker thing than a round we watched, but a named source.

## The company, in detail

What they build

Known for

genetic disease cure health care genetic medicine biotechnology research translational research immune-shielded vectors gene delivery biotechnology innovation cell targeting gene insertion metabolic gene therapy genetic correction hospital & health care gene therapy for children single administration therapy gene transfer

Built with from their website

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+8 more

jQuery RSS Yoast SEO Shutterstock Yoast Divi Wordpress Microsoft Exchange Online

- **Sector:** Research
- **Industry code:** NAICS 541714, SIC 8731
- **Region:** Lombardy
- **Revenue:** 1M a year, as listed
- **Full record:** [Every detail in the company directory](https://millionrounds.com/directory/genespire)

## Research in Italy

Startups like it

- [**Aptadir Therapeutics** Milano](https://millionrounds.com/startup/aptadir-therapeutics)
- [**Resalis Therapeutics** Turin · founded 2021](https://millionrounds.com/startup/resalis-therapeutics)
- [**Sibylla Biotech** Bresso · founded 2017](https://millionrounds.com/startup/sibylla-biotech)
- [**Algorithmiq** Milano · founded 2020](https://millionrounds.com/startup/algorithmiq)
- [**Phononic Vibes** Milan · founded 2018](https://millionrounds.com/startup/phononic-vibes-2)
- [**Contraria Biotech** Siena · founded 2017](https://millionrounds.com/startup/contraria-biotech)
- [**Cellply** Bologna · founded 2013](https://millionrounds.com/startup/cellply)
- [**Altheia Science** Milan · founded 2017](https://millionrounds.com/startup/altheia-science)

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