# Two Sigma Ventures Portfolio Map 2026: 51 Startups by Sector

> Two Sigma Ventures' portfolio mapped: 51 startups it has backed, in 8 sectors from AI, Biotech and Fintech on.

Source: https://millionrounds.com/portfolio-maps/two-sigma-ventures-portfolio-map (Millionrounds; every figure on the page links to its filing or article)

## AI

18

- [xAI](https://millionrounds.com/company/xai)
- [Enveda](https://millionrounds.com/company/enveda)
- [Socure](https://millionrounds.com/company/socure)
- [*R* RADAR](https://millionrounds.com/company/radar)
- [Anki](https://millionrounds.com/company/anki)
- [Terray Therapeutics](https://millionrounds.com/company/terray-therapeutics)
- [Artemis](https://millionrounds.com/company/artemis)
- [Osmo](https://millionrounds.com/company/osmo)
- [Jibo](https://millionrounds.com/company/jibo)
- [Kasisto](https://millionrounds.com/company/kasisto)
- [Verge Genomics](https://millionrounds.com/company/verge-genomics)
- [Pryon](https://millionrounds.com/company/pryon)
- [Formlogic](https://millionrounds.com/company/formlogic)
- [Distributional](https://millionrounds.com/company/distributional)
- [*S* Spell](https://millionrounds.com/company/spell)
- [Hyper](https://millionrounds.com/company/hyper)
- [Objective](https://millionrounds.com/company/objective)
- [Nullify](https://millionrounds.com/company/nullify)

## Biotech

8

- [Zymergen](https://millionrounds.com/company/zymergen)
- [Cajal Neuroscience](https://millionrounds.com/company/cajal-neuroscience)
- [Kallyope](https://millionrounds.com/company/kallyope)
- [Hexagon Bio](https://millionrounds.com/company/hexagon-bio)
- [Exai Bio](https://millionrounds.com/company/exai-bio)
- [Appia Bio](https://millionrounds.com/company/appia-bio)
- [Arda Therapeutics](https://millionrounds.com/company/arda-therapeutics)
- [Isabl Inc.](https://millionrounds.com/company/isabl-inc)

## Fintech

8

- [Nelo](https://millionrounds.com/company/nelo)
- [Highbeam](https://millionrounds.com/company/highbeam)
- [Membrane Labs](https://millionrounds.com/company/membrane-labs)
- [Ansel Health](https://millionrounds.com/company/ansel-health)
- [agentero](https://millionrounds.com/company/agentero)
- [RightRev](https://millionrounds.com/company/rightrev)
- [MonetizeNow](https://millionrounds.com/company/monetizenow)
- [Raincoat](https://millionrounds.com/company/raincoat)

## Big Data & Analytics

5

- [InsightSquared](https://millionrounds.com/company/insightsquared)
- [Anomalo](https://millionrounds.com/company/anomalo)
- [SDF](https://millionrounds.com/company/sdf)
- [Switchboard Software](https://millionrounds.com/company/switchboard-software)
- [Candu](https://millionrounds.com/company/candu)

## Healthtech

3

- [WHOOP](https://millionrounds.com/company/whoop)
- [Canary](https://millionrounds.com/company/canary)
- [Carbon Health](https://millionrounds.com/company/carbon-health)

## Cybersecurity

3

- [SecurityScorecard](https://millionrounds.com/company/securityscorecard)
- [Cerby](https://millionrounds.com/company/cerby)
- [Trustology](https://millionrounds.com/company/trustology)

## Internet

3

- [Pro.com](https://millionrounds.com/company/pro-com)
- [Placed](https://millionrounds.com/company/placed)
- [Spruce Up](https://millionrounds.com/company/spruce-up)

## Cloud

3

- [D2iq](https://millionrounds.com/company/d2iq)
- [Replicated](https://millionrounds.com/company/replicated)
- [Flatfile](https://millionrounds.com/company/flatfile)

## Segment by segment

### AI

18 startups · $82B raised

- [**xAI**](https://millionrounds.com/company/xai) United States $81B
- [**Enveda**](https://millionrounds.com/company/enveda) Enveda Biosciences is a clinical-stage biotechnology company founded in 2019, focused on accelerating drug discovery through an AI United States $461M
- [**Socure**](https://millionrounds.com/company/socure) Socure is a prominent American technology company that specializes in AI-driven digital identity verification, fraud prevention, a United States $273M
- [*R* **RADAR**](https://millionrounds.com/company/radar) United States $269M
- [**Anki**](https://millionrounds.com/company/anki) United States $158M
- [**Terray Therapeutics**](https://millionrounds.com/company/terray-therapeutics) Terray Therapeutics is a biotechnology company that propels drug discovery into the information age. United States $145M
- [**Artemis**](https://millionrounds.com/company/artemis) Artemis operates an intelligence platform for indoor farms. United States $79M
- [**Osmo**](https://millionrounds.com/company/osmo) Osmo is an AI-powered olfactory intelligence company founded in 2022, specializing in digitizing smell. United States $73M

### Biotech

8 startups · $1.3B raised

- [**Zymergen**](https://millionrounds.com/company/zymergen) United States $874M
- [**Cajal Neuroscience**](https://millionrounds.com/company/cajal-neuroscience) Cajal Neuroscience is a drug discovery company focused on neurodegenerative disease. United States $96M
- [**Kallyope**](https://millionrounds.com/company/kallyope) Kallyope uses the science of gut-brain biology to create medicines that transform human health. United States $95M
- [**Hexagon Bio**](https://millionrounds.com/company/hexagon-bio) Hexagon Bio is a biopharmaceutical company based in Menlo Park, California, founded in 2016. United States $77M
- [**Exai Bio**](https://millionrounds.com/company/exai-bio) Exai Bio is a biotechnology company based in Palo Alto, California, founded in 2021. United States $68M
- [**Appia Bio**](https://millionrounds.com/company/appia-bio) Appia Bio was a biotechnology company founded in 2020 and based in Culver City, California. United States $52M
- [**Arda Therapeutics**](https://millionrounds.com/company/arda-therapeutics) Arda Therapeutics is a biotechnology company based in the San Francisco Bay Area, founded in 2021. United States $43M
- [**Isabl Inc.**](https://millionrounds.com/company/isabl-inc) Isabl develops cancer diagnostic tests based on whole genome and RNA sequencing data. United States $2.0M

### Fintech

8 startups · $300M raised

- [**Nelo**](https://millionrounds.com/company/nelo) Nelo increases the buying power for consumers in LatAm. Mexico $200M
- [**Highbeam**](https://millionrounds.com/company/highbeam) Highbeam is a financial technology company based in New York, founded in 2021. United States $30M
- [**Membrane Labs**](https://millionrounds.com/company/membrane-labs) Membrane Labs is a fintech company established in 2019, specializing in digital asset credit infrastructure and prime services for United States $20M
- [**Ansel Health**](https://millionrounds.com/company/ansel-health) Ansel Health is a developer of a health insurance platform intended for employers to enhance their employee benefits. United States $20M
- [**agentero**](https://millionrounds.com/company/agentero) Agentero is an InsurTech and FinTech company founded in 2017 and based in Oakland, California. United States $14M
- [**RightRev**](https://millionrounds.com/company/rightrev) RightRev is a financial technology and enterprise software company founded in 2020 by Jagan Reddy, based in Santa Clara, Californi United States $13M
- [**MonetizeNow**](https://millionrounds.com/company/monetizenow) MonetizeNow is the World's First Unified CPQ, Billing and Usage Platform Built For B2B SaaS United States $3.0M
- [**Raincoat**](https://millionrounds.com/company/raincoat) Raincoat is a technology company that creates an operating system designed to connect insurance providers, reinsurers, distributor Puerto Rico $150K

### Big Data & Analytics

5 startups · $79M raised

- [**InsightSquared**](https://millionrounds.com/company/insightsquared) InsightSquared is a revenue intelligence platform that provides sales intelligence solutions for forecasting, accuracy, and decision-making. United States $50M
- [**Anomalo**](https://millionrounds.com/company/anomalo) Anomalo is a Palo Alto-based company founded in 2018 that specializes in AI-powered data quality and observability. United States $10M
- [**SDF**](https://millionrounds.com/company/sdf) SDF is a compiler and build system that leverages static analysis to comprehensively examine SQL code at a warehouse scale. United States $9.0M
- [**Switchboard Software**](https://millionrounds.com/company/switchboard-software) Switchboard Software is an enterprise-grade data engineering automation platform founded in 2013 and based in San Francisco, California. United States $7.0M
- [**Candu**](https://millionrounds.com/company/candu) Candu is a product experience platform for software teams who want to design, refine, and personalize their application’s user interface. United States $3.0M

### Healthtech

3 startups · $1.5B raised

- [**WHOOP**](https://millionrounds.com/company/whoop) WHOOP is a performance optimization system that tracks athlete recovery, training, and sleeping hours to help boost performance. United States $1.3B
- [**Canary**](https://millionrounds.com/company/canary) Canary is the first partner of choice of the best founders in LatAm. United States $177M
- [**Carbon Health**](https://millionrounds.com/company/carbon-health) Carbon Health is a technology-enabled chain of primary and urgent care clinics founded in 2015 in San Francisco. United States $56M

### Cybersecurity

3 startups · $326M raised

- [**SecurityScorecard**](https://millionrounds.com/company/securityscorecard) SecurityScorecard is a leader in cybersecurity ratings and third-party risk management, providing AI-driven solutions for continuo United States $278M
- [**Cerby**](https://millionrounds.com/company/cerby) Cerby is an identity automation platform founded in 2020 and based in Alameda, California. United States $40M
- [**Trustology**](https://millionrounds.com/company/trustology) Trustology is building a custody platform to safeguard your crypto assets. United Kingdom $8.0M

### Internet

3 startups · $68M raised

- [**Pro.com**](https://millionrounds.com/company/pro-com) Tiberius in a letter to him saith, Haec pro amicitia nostra non occultavi; and the whole senate dedicated an altar to Friendship, United States $51M
- [**Placed**](https://millionrounds.com/company/placed) Placed is a location-driven insights and mobile ad intelligence platform that provides reports on consumers’ offline behaviors. United States $13M
- [**Spruce Up**](https://millionrounds.com/company/spruce-up) Spruce Up from a product to a brand A fresh new perspective can change everything about a brand. United States $4.5M

### Cloud

3 startups · $234M raised

- [**D2iq**](https://millionrounds.com/company/d2iq) D2iQ offers elastically run containers and data services at scale, with complete hybrid cloud portability. United States $125M
- [**Replicated**](https://millionrounds.com/company/replicated) Replicated is a technology company based in Los Angeles, specializing in software distribution for self-hosted and enterprise environments. United States $57M
- [**Flatfile**](https://millionrounds.com/company/flatfile) The Flatfile Data Exchange Platform is the easiest, fastest, and safest way for developers to build the ideal data file import experience. United States $52M

**How this map is made.** Every startup here has raised money in a round we track that names Two Sigma Ventures as an investor, the first in 2013. Each sits under its main sector, read from its rounds, and each shows its best-funded first. Rebuilt nightly; updated 15 November 2026.

## More portfolio maps

[All portfolios](https://millionrounds.com/portfolio-maps)

[Co-investors **Who invests with Two Sigma Ventures** 78 co-investors](https://millionrounds.com/portfolio-maps/two-sigma-ventures-co-investors)[Sector portfolio **Two Sigma Ventures' AI portfolio** 16 startups · $82B](https://millionrounds.com/portfolio-maps/two-sigma-ventures-ai-portfolio)[Portfolio map **Techstars portfolio map** 1,119 startups · $16B](https://millionrounds.com/portfolio-maps/techstars-portfolio-map)[Portfolio map **Alumni Ventures portfolio map** 745 startups · $64B](https://millionrounds.com/portfolio-maps/us-strategic-tech-fund-an-alumni-ventures-fund-portfolio-map)[Portfolio map **Andreessen Horowitz portfolio map** 694 startups · $497B](https://millionrounds.com/portfolio-maps/andreessen-horowitz-portfolio-map)[Portfolio map **Sequoia Capital portfolio map** 651 startups · $677B](https://millionrounds.com/portfolio-maps/sequoia-capital-portfolio-map)

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