# Two Sigma Ventures' AI Investments: 16 Startups in Its Portfolio (2026)

> The 16 AI startups Two Sigma Ventures has backed, by stage: $82B raised between them. From the rounds we track; updated nightly.

Source: https://millionrounds.com/portfolio-maps/two-sigma-ventures-ai-portfolio (Millionrounds; every figure on the page links to its filing or article)

## Stage not reported

5

- [Kasisto](https://millionrounds.com/company/kasisto)
- [Verge Genomics](https://millionrounds.com/company/verge-genomics)
- [Pryon](https://millionrounds.com/company/pryon)
- [Formlogic](https://millionrounds.com/company/formlogic)
- [*S* Spell](https://millionrounds.com/company/spell)

## Series B

4

- [*R* RADAR](https://millionrounds.com/company/radar)
- [Terray Therapeutics](https://millionrounds.com/company/terray-therapeutics)
- [Osmo](https://millionrounds.com/company/osmo)
- [Jibo](https://millionrounds.com/company/jibo)

## Pre-seed and seed

4

- [Artemis](https://millionrounds.com/company/artemis)
- [Hyper](https://millionrounds.com/company/hyper)
- [Objective](https://millionrounds.com/company/objective)
- [Nullify](https://millionrounds.com/company/nullify)

## Series C and later

3

- [xAI](https://millionrounds.com/company/xai)
- [Enveda](https://millionrounds.com/company/enveda)
- [Anki](https://millionrounds.com/company/anki)

## Segment by segment

### Stage not reported

5 startups · $137M raised

- [**Kasisto**](https://millionrounds.com/company/kasisto) Kasisto's enables financial institutions to service, engage, and acquire customers. United States $41M
- [**Verge Genomics**](https://millionrounds.com/company/verge-genomics) Verge Genomics uses machine learning and human genomics to accelerate drug discovery. United States $36M
- [**Pryon**](https://millionrounds.com/company/pryon) Pryon is an enterprise AI company that specializes in enhancing information retrieval through its core product, the Pryon Memory Layer. United States $25M
- [**Formlogic**](https://millionrounds.com/company/formlogic) Formlogic is an autonomous manufacturing company that uses machine learning and physics simulation to precision parts. United States $20M
- [*S* **Spell**](https://millionrounds.com/company/spell) Spell is the MLOps platform built to meet the unique challenges of operationalizing deep learning at scale. United States $15M

### Series B

4 startups · $538M raised

- [*R* **RADAR**](https://millionrounds.com/company/radar) United States $269M
- [**Terray Therapeutics**](https://millionrounds.com/company/terray-therapeutics) Terray Therapeutics is a biotechnology company that propels drug discovery into the information age. United States $145M
- [**Osmo**](https://millionrounds.com/company/osmo) Osmo is an AI-powered olfactory intelligence company founded in 2022, specializing in digitizing smell. United States $73M
- [**Jibo**](https://millionrounds.com/company/jibo) Jibo, Inc. United States $52M

### Pre-seed and seed

4 startups · $118M raised

- [**Artemis**](https://millionrounds.com/company/artemis) Artemis operates an intelligence platform for indoor farms. United States $79M
- [**Hyper**](https://millionrounds.com/company/hyper) Explore HyperBot, HyperDesk, HyperClaw, and HyperBuild. United States $13M
- [**Objective**](https://millionrounds.com/company/objective) Objective provides a browser extension that allows users to personalize priorities, adding filters, and contextualized data. United States $13M
- [**Nullify**](https://millionrounds.com/company/nullify) Nullify is an AI-first application security company that provides an autonomous AI workforce for product security. United States $13M

### Series C and later

3 startups · $81B raised

- [**xAI**](https://millionrounds.com/company/xai) United States $81B
- [**Enveda**](https://millionrounds.com/company/enveda) Enveda Biosciences is a clinical-stage biotechnology company founded in 2019, focused on accelerating drug discovery through an AI United States $461M
- [**Anki**](https://millionrounds.com/company/anki) United States $158M

**How this map is made.** Every startup here works in AI and has raised money in a round we track that names Two Sigma Ventures as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026.

## More portfolio maps

[All portfolios](https://millionrounds.com/portfolio-maps)

[Co-investors **Who invests with Two Sigma Ventures** 78 co-investors](https://millionrounds.com/portfolio-maps/two-sigma-ventures-co-investors)[Portfolio map **Two Sigma Ventures portfolio map** 51 startups · $86B](https://millionrounds.com/portfolio-maps/two-sigma-ventures-portfolio-map)[Sector portfolio **Techstars' AI portfolio** 336 startups · $4.9B](https://millionrounds.com/portfolio-maps/techstars-ai-portfolio)[Sector portfolio **Alumni Ventures' AI portfolio** 302 startups · $36B](https://millionrounds.com/portfolio-maps/us-strategic-tech-fund-an-alumni-ventures-fund-ai-portfolio)[Sector portfolio **Andreessen Horowitz's AI portfolio** 259 startups · $426B](https://millionrounds.com/portfolio-maps/andreessen-horowitz-ai-portfolio)[Sector portfolio **General Catalyst's AI portfolio** 226 startups · $179B](https://millionrounds.com/portfolio-maps/general-catalyst-ai-portfolio)

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