# The Column Group's Biotech Investments: 19 Startups in Its Portfolio (2026)

> The 19 Biotech startups The Column Group has backed, by stage: $1.8B raised between them. From the rounds we track; updated nightly.

Source: https://millionrounds.com/portfolio-maps/the-column-group-biotech-portfolio (Millionrounds; every figure on the page links to its filing or article)

## Series C and later

7

- [Peloton Therapeutics](https://millionrounds.com/company/peloton-therapeutics)
- [*3B* 3-V Biosciences](https://millionrounds.com/company/3-v-biosciences)
- [Aragon Pharmaceuticals](https://millionrounds.com/company/aragon-pharmaceuticals)
- [Effector Therapeutics](https://millionrounds.com/company/effector-therapeutics)
- [Plexium](https://millionrounds.com/company/plexium)
- [*FB* FLX Bio](https://millionrounds.com/company/flx-bio)
- [*O* ORIC](https://millionrounds.com/company/oric)

## Stage not reported

5

- [*ID* Immune Design](https://millionrounds.com/company/immune-design)
- [Ribon Therapeutics](https://millionrounds.com/company/ribon-therapeutics)
- [*I* Igenica](https://millionrounds.com/company/igenica)
- [Flexus Biosciences](https://millionrounds.com/company/flexus-biosciences)
- [Carmot Therapeutics](https://millionrounds.com/company/carmot-therapeutics)

## Series B

4

- [Surrozen](https://millionrounds.com/company/surrozen)
- [Tenaya Therapeutics](https://millionrounds.com/company/tenaya-therapeutics)
- [Kallyope](https://millionrounds.com/company/kallyope)
- [Gritstone](https://millionrounds.com/company/gritstone)

## Series A

3

- [A2 Biotherapeutics](https://millionrounds.com/company/a2-biotherapeutics)
- [Escient](https://millionrounds.com/company/escient)
- [*A* Accent](https://millionrounds.com/company/accent)

## Segment by segment

### Series C and later

7 startups · $755M raised

- [**Peloton Therapeutics**](https://millionrounds.com/company/peloton-therapeutics) Peloton Therapeutics, a biotech company based in Dallas, is involved in discovering and developing novel drugs for cancer treatments. United States $190M
- [*3B* **3-V Biosciences**](https://millionrounds.com/company/3-v-biosciences) United States $146M
- [**Aragon Pharmaceuticals**](https://millionrounds.com/company/aragon-pharmaceuticals) Aragon Pharmaceuticals develops therapeutics for the treatment of hormone-resistant cancers such as prostate and breast cancer. United States $122M
- [**Effector Therapeutics**](https://millionrounds.com/company/effector-therapeutics) Effector Therapeutics is an early-stage company focused on the discovery and development of small molecule cancer therapeutics. United States $99M
- [**Plexium**](https://millionrounds.com/company/plexium) Plexium is a biotechnology company based in San Diego, California, founded in 2018. United States $88M
- [*FB* **FLX Bio**](https://millionrounds.com/company/flx-bio) United States $60M
- [*O* **ORIC**](https://millionrounds.com/company/oric) United States $50M

### Stage not reported

5 startups · $332M raised

- [*ID* **Immune Design**](https://millionrounds.com/company/immune-design) Immune Design develops vaccines and therapeutics for the prevention and treatment of infectious diseases. United States $99M
- [**Ribon Therapeutics**](https://millionrounds.com/company/ribon-therapeutics) Ribon Therapeutics is a biotechnology company focused on the development of therapeutics treatments targeting stress support pathways. United States $90M
- [*I* **Igenica**](https://millionrounds.com/company/igenica) Igenica engages in discovery and development of antibody-based therapeutics for the treatment of cancer. United States $88M
- [**Flexus Biosciences**](https://millionrounds.com/company/flexus-biosciences) Flexus Biosciences is a biotechnology company based in San Carlos, California, founded in 2013. United States $53M
- [**Carmot Therapeutics**](https://millionrounds.com/company/carmot-therapeutics) Carmot Therapeutics provides drugs to treat inflammatory, metabolic, and neurological diseases. United States $2.1M

### Series B

4 startups · $598M raised

- [**Surrozen**](https://millionrounds.com/company/surrozen) Surrozen is a biopharmaceutical that focuses on unlocking the body’s regenerative power to treat injury and disease. United States $258M
- [**Tenaya Therapeutics**](https://millionrounds.com/company/tenaya-therapeutics) Tenaya Therapeutics is a developer of novel therapies designed to offer treatment for heart disease. United States $152M
- [**Kallyope**](https://millionrounds.com/company/kallyope) Kallyope uses the science of gut-brain biology to create medicines that transform human health. United States $95M
- [**Gritstone**](https://millionrounds.com/company/gritstone) A Dallas based sales & marketing firm that specializes in face to face engagements. United States $93M

### Series A

3 startups · $137M raised

- [**A2 Biotherapeutics**](https://millionrounds.com/company/a2-biotherapeutics) A2 Biotherapeutics is an early-stage biotechnology company that develops medicines for serious illnesses. United States $57M
- [**Escient**](https://millionrounds.com/company/escient) Escient specializes in providing business strategies, management consulting, and advisory services for various organizations. United States $40M
- [*A* **Accent**](https://millionrounds.com/company/accent) United States $40M

**How this map is made.** Every startup here works in Biotech and has raised money in a round we track that names The Column Group as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026.

## More portfolio maps

[All portfolios](https://millionrounds.com/portfolio-maps)

[Co-investors **Who invests with The Column Group** 25 co-investors](https://millionrounds.com/portfolio-maps/the-column-group-co-investors)[Sector portfolio **Techstars' AI portfolio** 336 startups · $4.9B](https://millionrounds.com/portfolio-maps/techstars-ai-portfolio)[Sector portfolio **Alumni Ventures' AI portfolio** 302 startups · $36B](https://millionrounds.com/portfolio-maps/us-strategic-tech-fund-an-alumni-ventures-fund-ai-portfolio)[Sector portfolio **Andreessen Horowitz's AI portfolio** 259 startups · $426B](https://millionrounds.com/portfolio-maps/andreessen-horowitz-ai-portfolio)[Sector portfolio **General Catalyst's AI portfolio** 226 startups · $179B](https://millionrounds.com/portfolio-maps/general-catalyst-ai-portfolio)[Sector portfolio **Sequoia Capital's AI portfolio** 209 startups · $543B](https://millionrounds.com/portfolio-maps/sequoia-capital-ai-portfolio)

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