# Small Business Innovation Research Portfolio Map 2026: 51 Startups by Sector

> Small Business Innovation Research's portfolio mapped: 51 startups it has backed, in 8 sectors from Biotech, Healthtech and AI on.

Source: https://millionrounds.com/portfolio-maps/small-business-innovation-research-portfolio-map (Millionrounds; every figure on the page links to its filing or article)

## Biotech

13

- [Cell Microsystems](https://millionrounds.com/company/cell-microsystems)
- [Spirovant](https://millionrounds.com/company/spirovant)
- [Hemex Health](https://millionrounds.com/company/hemex-health)
- [*AT* Avexegen Therapeutics](https://millionrounds.com/company/avexegen-therapeutics)
- [Prolocor](https://millionrounds.com/company/prolocor)
- [Kepley BioSystems](https://millionrounds.com/company/kepley-biosystems)
- [Photonic Pharma](https://millionrounds.com/company/photonic-pharma)
- [Neuroene Therapeutics](https://millionrounds.com/company/neuroene-therapeutics)
- [Pathotrak](https://millionrounds.com/company/pathotrak)
- [HC Simulation](https://millionrounds.com/company/hc-simulation)
- [Cellular Logistics](https://millionrounds.com/company/cellular-logistics)
- [Veana Therapeutics](https://millionrounds.com/company/veana-therapeutics)
- [Kalocyte](https://millionrounds.com/company/kalocyte)

## Healthtech

8

- [SPR Therapeutics](https://millionrounds.com/company/spr-therapeutics)
- [AIQ Solutions](https://millionrounds.com/company/aiq-solutions)
- [GeniPhys](https://millionrounds.com/company/geniphys)
- [Obsidio](https://millionrounds.com/company/obsidio)
- [Ayuda Medical](https://millionrounds.com/company/ayuda-medical)
- [Symple Surgical](https://millionrounds.com/company/symple-surgical)
- [Nucleic Sensing Systems](https://millionrounds.com/company/nucleic-sensing-systems)
- [Secmation](https://millionrounds.com/company/secmation)

## AI

8

- [IAMBIC](https://millionrounds.com/company/iambic)
- [Abstractive Health](https://millionrounds.com/company/abstractive-health)
- [Softhread](https://millionrounds.com/company/softhread)
- [RedShred](https://millionrounds.com/company/redshred)
- [Choosito](https://millionrounds.com/company/choosito)
- [Ada IQ](https://millionrounds.com/company/ada-iq)
- [GIANT BioSystems](https://millionrounds.com/company/giant-biosystems)
- [Oqullo](https://millionrounds.com/company/oqullo)

## Edtech

6

- [*O* Ocupath](https://millionrounds.com/company/ocupath)
- [MathBRIX](https://millionrounds.com/company/mathbrix)
- [Literably](https://millionrounds.com/company/literably)
- [2Sigma School](https://millionrounds.com/company/2sigma-school)
- [Just Physiology](https://millionrounds.com/company/just-physiology)
- [Parametric Studio](https://millionrounds.com/company/parametric-studio)

## Aerospace & Space

6

- [ExoTerra](https://millionrounds.com/company/exoterra)
- [bluShift Aerospace](https://millionrounds.com/company/blushift-aerospace)
- [QubitSolve](https://millionrounds.com/company/qubitsolve)
- [VertiPrime Government Services](https://millionrounds.com/company/vertiprime-government-services)
- [Vestigo Aerospace](https://millionrounds.com/company/vestigo-aerospace)
- [Elemental Coatings](https://millionrounds.com/company/elemental-coatings)

## Big Data & Analytics

4

- [Accrete AI](https://millionrounds.com/company/accrete-ai)
- [FIRMM](https://millionrounds.com/company/firmm)
- [Maalka](https://millionrounds.com/company/maalka)
- [Atheraxon](https://millionrounds.com/company/atheraxon)

## Pharma

3

- [Stem Pharm](https://millionrounds.com/company/stem-pharm)
- [Cytocybernetics](https://millionrounds.com/company/cytocybernetics)
- [*SB* Sonoran Biosciences](https://millionrounds.com/company/sonoran-biosciences)

## Cleantech

3

- [MagDrive Technologies](https://millionrounds.com/company/magdrive-technologies)
- [RiKarbon](https://millionrounds.com/company/rikarbon)
- [Lunexus Space](https://millionrounds.com/company/lunexus-space)

## Segment by segment

### Biotech

13 startups · $21M raised

- [**Cell Microsystems**](https://millionrounds.com/company/cell-microsystems) Cell Microsystems is a biotechnology company based in Durham, North Carolina, founded in 2010. United States $6.5M
- [**Spirovant**](https://millionrounds.com/company/spirovant) Spirovant Sciences is developing novel gene therapies for cystic fibrosis and other pulmonary diseases. - $4.5M
- [**Hemex Health**](https://millionrounds.com/company/hemex-health) Hemex Health is a provider of a diagnostic device designed for populations at risk for malaria and sickle cell disease. United States $3.0M
- [*AT* **Avexegen Therapeutics**](https://millionrounds.com/company/avexegen-therapeutics) Avexegen Therapeutics is a biotechnology company developing therapies for gastrointestinal disorders. - $2.9M
- [**Prolocor**](https://millionrounds.com/company/prolocor) Prolocor is a biotechnology and healthcare startup based in Philadelphia, Pennsylvania, founded in 2020. United States $1.7M
- [**Kepley BioSystems**](https://millionrounds.com/company/kepley-biosystems) Kepley BioSystems offers ocean restorative technology to help stem the continued depletion of wild fish. United States $1.0M
- [**Photonic Pharma**](https://millionrounds.com/company/photonic-pharma) Photonic Pharma is an early phase of drug development - $499K
- [**Neuroene Therapeutics**](https://millionrounds.com/company/neuroene-therapeutics) Developing mitochondrial small molecule drugs for difficult to treat neurological diseases. United States $400K

### Healthtech

8 startups · $114M raised

- [**SPR Therapeutics**](https://millionrounds.com/company/spr-therapeutics) SPR Therapeutics is a medical device company. United States $101M
- [**AIQ Solutions**](https://millionrounds.com/company/aiq-solutions) AIQ Solutions develops a medical device technology platform that revolutionizes the treatment response of patients with complex diseases. United States $3.6M
- [**GeniPhys**](https://millionrounds.com/company/geniphys) GeniPhys is a medical technology company that plans to develop and commercialize its patented technology. United States $3.0M
- [**Obsidio**](https://millionrounds.com/company/obsidio) Obsidio is a medical device company pioneering a biomaterial platform technology to enable minimally-invasive occlusion of blood vessels. - $3.0M
- [**Ayuda Medical**](https://millionrounds.com/company/ayuda-medical) Ayuda Medical is a medical device company that develops wearable devices and sensors to detect an overdose and call for help. United States $2.8M
- [**Symple Surgical**](https://millionrounds.com/company/symple-surgical) Symple Surgical is a medical device company focusing on developing novel therapeutic technologies through controlled microwave ablation. United States $400K
- [**Nucleic Sensing Systems**](https://millionrounds.com/company/nucleic-sensing-systems) Nucleic Sensing Systems is an environmental biotechnology company based in Saint Paul, Minnesota, founded in 2020. United States $175K
- [**Secmation**](https://millionrounds.com/company/secmation) Secmation offers technology, engineering solutions, and tools to integrate information security into industrial and defense products. United States $59K

### AI

8 startups · $171M raised

- [**IAMBIC**](https://millionrounds.com/company/iambic) AI-driven, precision-fit footwear. United States $167M
- [**Abstractive Health**](https://millionrounds.com/company/abstractive-health) Abstractive Health is a New York-based healthcare AI company founded in 2022. United States $1.4M
- [**Softhread**](https://millionrounds.com/company/softhread) Softhread is a blockchain technology company that develops enterprise solutions using a blockchain and AI-enabled platform. United States $1.0M
- [**RedShred**](https://millionrounds.com/company/redshred) RedShred is an artificial intelligence startup. - $894K
- [**Choosito**](https://millionrounds.com/company/choosito) Choosito! United States $325K
- [**Ada IQ**](https://millionrounds.com/company/ada-iq) AI-driven platform assists product managers, designers, and related professionals in having better insights into customers' needs United States $275K
- [**GIANT BioSystems**](https://millionrounds.com/company/giant-biosystems) GIANT BioSystems is a developer of an ultra-fast, next-generation platform for AST and high-throughput drug screening. United States $250K
- [**Oqullo**](https://millionrounds.com/company/oqullo) Oqullo provides property managers with actionable insight into customer traffic. United States $250K

### Edtech

6 startups · $4.7M raised

- [*O* **Ocupath**](https://millionrounds.com/company/ocupath) Ocupath is seeks to modernize job shadowing and job training through augmented and virtual reality. - $1.0M
- [**MathBRIX**](https://millionrounds.com/company/mathbrix) MathBRIX is a highly visual, concept-based approach to teaching math, backed by decades of research. United States $1.0M
- [**Literably**](https://millionrounds.com/company/literably) Literably is a K-8 literacy assessment system that sends results to teachers after students read out loud into a device. United States $1.0M
- [**2Sigma School**](https://millionrounds.com/company/2sigma-school) 2Sigma School provides courses in computer science and data science. United States $1.0M
- [**Just Physiology**](https://millionrounds.com/company/just-physiology) JustPhysiology is an online learning resource composed of interactive experiments powered by HumModTM. - $441K
- [**Parametric Studio**](https://millionrounds.com/company/parametric-studio) Parametric Studio is an Ed-Tech company specialized in developing engineering-centric and project based STEM software products. - $225K

### Aerospace & Space

6 startups · $12M raised

- [**ExoTerra**](https://millionrounds.com/company/exoterra) ExoTerra's mission is to enable more exploration of space by making it affordable to a larger market. United States $8.0M
- [**bluShift Aerospace**](https://millionrounds.com/company/blushift-aerospace) Scalable, reusable propulsion for defense and space. United States $1.3M
- [**QubitSolve**](https://millionrounds.com/company/qubitsolve) QubitSolve is developing a software that helps helps engineers in conducting fast and accurate CFD simulations on quantum computers. United States $1.2M
- [**VertiPrime Government Services**](https://millionrounds.com/company/vertiprime-government-services) VertiPrime Government Services is a service disable veteran owned full spectrum solution provider. - $1.0M
- [**Vestigo Aerospace**](https://millionrounds.com/company/vestigo-aerospace) Vestigo Aerospace provides deorbit capability for cubeSats, small satellites, and launch vehicle stages. United States $375K
- [**Elemental Coatings**](https://millionrounds.com/company/elemental-coatings) Elemental Coatings, based in Houston, Texas, is a chemical manufacturing company founded in 2018. United States $150K

### Big Data & Analytics

4 startups · $49M raised

- [**Accrete AI**](https://millionrounds.com/company/accrete-ai) Dual Use AI for defense, Intelligence and cybersecurity. United States $40M
- [**FIRMM**](https://millionrounds.com/company/firmm) FIRMM is a real-time MRI quality metrics to reduce costs and improve quality. - $6.6M
- [**Maalka**](https://millionrounds.com/company/maalka) Cities, corporations, and large building portfolio owners use Maalka manage sustainability for thousands of buildings at a time. - $1.0M
- [**Atheraxon**](https://millionrounds.com/company/atheraxon) Atheraxon is an Atlanta-based company specializing in industrial location and spatial intelligence. United States $1.0M

### Pharma

3 startups · $3.8M raised

- [**Stem Pharm**](https://millionrounds.com/company/stem-pharm) Stem Pharm's synthetic biomaterials support the optimization of cell expansion. United States $2.6M
- [**Cytocybernetics**](https://millionrounds.com/company/cytocybernetics) Cytocybernetics is a Biotechnology which specializes in cellular electrophysiology United States $1.0M
- [*SB* **Sonoran Biosciences**](https://millionrounds.com/company/sonoran-biosciences) Sonoran Biosciences is an early stage pharmaceutical company that has developed SB Gel, the first viscous sustained release carrier. United States $260K

### Cleantech

3 startups · $4.9M raised

- [**MagDrive Technologies**](https://millionrounds.com/company/magdrive-technologies) MagDrive Technologies is a magnetically actuated valve drive capable of producing torque. United States $3.5M
- [**RiKarbon**](https://millionrounds.com/company/rikarbon) RiKarbon is a green-tech company that develops renewable products using captured carbon emissions by minimizing waste through innovation. United States $1.1M
- [**Lunexus Space**](https://millionrounds.com/company/lunexus-space) Energizing the Circular Economy in Space United States $275K

**How this map is made.** Every startup here has raised money in a round we track that names Small Business Innovation Research as an investor, the first in 2014. Each sits under its main sector, read from its rounds, and each sector shows its best-funded first; sectors with fewer than three companies are left off. Rebuilt nightly; updated 15 November 2026.

## More portfolio maps

[All portfolios](https://millionrounds.com/portfolio-maps)

[Government fund · United States **National Science Foundation** 988 startups · 12 sectors · $10B](https://millionrounds.com/portfolio-maps/nsf-small-business-innovation-research-small-business-techno-portfolio-map)[Government fund · United States **US Department of Energy** 259 startups · 12 sectors · $38B](https://millionrounds.com/portfolio-maps/u-s-department-of-energy-portfolio-map)[Government fund · United States **National Institutes of Health** 232 startups · 7 sectors · $3.3B](https://millionrounds.com/portfolio-maps/national-institutes-of-health-portfolio-map)[Government fund · United States **International Finance Corporation** 134 startups · 12 sectors · $23B](https://millionrounds.com/portfolio-maps/international-finance-corporation-ifc-portfolio-map)[Government fund · United States **Connecticut Innovations** 93 startups · 12 sectors · $2.5B](https://millionrounds.com/portfolio-maps/connecticut-innovations-portfolio-map)[Government fund · United States **Innovation Works** 88 startups · 12 sectors · $1.2B](https://millionrounds.com/portfolio-maps/innovation-works-portfolio-map)

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