# Safeguard Scientifics Portfolio Map 2026: 20 Startups by Sector > Safeguard Scientifics's portfolio mapped: 20 startups it has backed, in 5 sectors from Biotech, Healthtech and Advertising & Adtech on. Source: https://millionrounds.com/portfolio-maps/safeguard-scientifics-portfolio-map (Millionrounds; every figure on the page links to its filing or article) ## Biotech 7 - [NuPathe](https://millionrounds.com/company/nupathe) - [Propeller Health](https://millionrounds.com/company/propeller-health) - [Velano Vascular](https://millionrounds.com/company/velano-vascular) - [Syapse](https://millionrounds.com/company/syapse) - [Quinnova Pharmaceuticals](https://millionrounds.com/company/quinnova-pharmaceuticals) - [*GB* Garnet Biotherapeutics](https://millionrounds.com/company/garnet-biotherapeutics) - [Cellumen](https://millionrounds.com/company/cellumen) ## Healthtech 4 - [Sotera Wireless](https://millionrounds.com/company/sotera-wireless) - [Moxe Health](https://millionrounds.com/company/moxe-health) - [Trice Medical](https://millionrounds.com/company/trice-medical) - [Advantedge Healthcare Solutions](https://millionrounds.com/company/advantedge-healthcare-solutions) ## Advertising & Adtech 3 - [MediaMath](https://millionrounds.com/company/mediamath) - [Spongecell](https://millionrounds.com/company/spongecell) - [Sonobi](https://millionrounds.com/company/sonobi) ## IT Services 3 - [Apprenda](https://millionrounds.com/company/apprenda) - [AppFirst](https://millionrounds.com/company/appfirst) - [Pneuron](https://millionrounds.com/company/pneuron) ## Fintech 3 - [*C* Clutch](https://millionrounds.com/company/clutch) - [Transactis](https://millionrounds.com/company/transactis) - [*TG* T-Rex Group](https://millionrounds.com/company/t-rex-group) ## Segment by segment ### Biotech 7 startups · $317M raised - [**NuPathe**](https://millionrounds.com/company/nupathe) NuPathe is a pharmaceutical company developing solutions for diseases of the CNS, including neurological and psychiatric disorders. United States $93M - [**Propeller Health**](https://millionrounds.com/company/propeller-health) Propeller Health, now operating as Reciprocal Labs Corporation under ResMed, was a digital therapeutics company founded in 2010. United States $70M - [**Velano Vascular**](https://millionrounds.com/company/velano-vascular) Velano Vascular is a medical device innovator committed to enhancing both inpatient blood collection and vascular access United States $58M - [**Syapse**](https://millionrounds.com/company/syapse) Syapse is a real-world evidence company dedicated to extinguishing the fear and burden of serious disease by advancing real-world United States $45M - [**Quinnova Pharmaceuticals**](https://millionrounds.com/company/quinnova-pharmaceuticals) Quinnova Pharmaceuticals is a biotech company engaged in the development and commercialization of prescription drug products. United States $31M - [*GB* **Garnet Biotherapeutics**](https://millionrounds.com/company/garnet-biotherapeutics) Garnet BioTherapeutics is a cell therapy company specializing in dermal-based regenerative therapy. United States $10M - [**Cellumen**](https://millionrounds.com/company/cellumen) Cellumen is an innovator in cellular systems biology solutions that provides an accurate predictions of drug efficacy and safety. United States $10M ### Healthtech 4 startups · $232M raised - [**Sotera Wireless**](https://millionrounds.com/company/sotera-wireless) Sotera Wireless is a medical device company developing wireless vital signs monitoring devices. United States $92M - [**Moxe Health**](https://millionrounds.com/company/moxe-health) Moxe Health streamlines the bi-directional exchange of clinical data between health plans and provider systems. United States $61M - [**Trice Medical**](https://millionrounds.com/company/trice-medical) Trice Medical specializes in providing solutions for orthopedic diagnostics. United States $60M - [**Advantedge Healthcare Solutions**](https://millionrounds.com/company/advantedge-healthcare-solutions) Advantedge Healthcare Solutions designs and develops software for the healthcare industry. United States $20M ### Advertising & Adtech 3 startups · $636M raised - [**MediaMath**](https://millionrounds.com/company/mediamath) Created by MediaMath's industry veterans, the TerminalOneTM Marketing Operating System increases profits and efficiency in digital United States $605M - [**Spongecell**](https://millionrounds.com/company/spongecell) Spongecell helps brands connect with customers wherever they may be. United States $21M - [**Sonobi**](https://millionrounds.com/company/sonobi) Sonobi is an advertising technology company founded in 2012 and based in Winter Park, Florida. United States $10M ### IT Services 3 startups · $88M raised - [**Apprenda**](https://millionrounds.com/company/apprenda) Apprenda was a software company based in Troy, NY, founded in 2007. United States $55M - [**AppFirst**](https://millionrounds.com/company/appfirst) AppFirst is redefining the possibilities afforded by next generation IT infrastructure and investments through unprecedented visibility. United States $20M - [**Pneuron**](https://millionrounds.com/company/pneuron) Pneuron overcomes the time, cost, and complexity associated with traditional enterprise development, deployment and integration approaches. United States $13M ### Fintech 3 startups · $169M raised - [*C* **Clutch**](https://millionrounds.com/company/clutch) United States $122M - [**Transactis**](https://millionrounds.com/company/transactis) Transactis provides banks and merchants with SaaS-based billing, payment, and loyalty products. United States $37M - [*TG* **T-Rex Group**](https://millionrounds.com/company/t-rex-group) United States $10M **How this map is made.** Every startup here has raised money in a round we track that names Safeguard Scientifics as an investor, the first in 2006. Each sits under its main sector, read from its rounds, and each sector shows its best-funded first; sectors with fewer than three companies are left off. Rebuilt nightly; updated 15 November 2026. ## More portfolio maps [All portfolios](https://millionrounds.com/portfolio-maps) [Private equity · United States **Gaingels** 493 startups · 12 sectors · $40B](https://millionrounds.com/portfolio-maps/gaingels-portfolio-map)[Private equity · United States **Goldman Sachs** 294 startups · 12 sectors · $163B](https://millionrounds.com/portfolio-maps/goldman-sachs-portfolio-map)[Private equity · United States **Pioneer Fund** 289 startups · 12 sectors · $5.9B](https://millionrounds.com/portfolio-maps/pioneer-fund-2-portfolio-map)[Private equity · United States **RA Capital Management** 264 startups · 5 sectors · $48B](https://millionrounds.com/portfolio-maps/ra-capital-management-portfolio-map)[Private equity · United States **OrbiMed** 221 startups · 4 sectors · $34B](https://millionrounds.com/portfolio-maps/orbimed-portfolio-map)[Private equity · United States **Cormorant Asset Management** 123 startups · 3 sectors · $25B](https://millionrounds.com/portfolio-maps/cormorant-asset-management-portfolio-map) ## Raising from investors like Safeguard Scientifics? 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