# Pappas Ventures' Biotech Investments: 13 Startups in Its Portfolio (2026) > The 13 Biotech startups Pappas Ventures has backed, by stage: $784M raised between them. From the rounds we track; updated nightly. Source: https://millionrounds.com/portfolio-maps/pappas-ventures-biotech-portfolio (Millionrounds; every figure on the page links to its filing or article) ## Series A 8 - [*MT* Mirum Therapeutics](https://millionrounds.com/company/mirum-therapeutics) - [*RP* Reneo Pharmaceuticals](https://millionrounds.com/company/reneo-pharmaceuticals) - [*C* CuraSen](https://millionrounds.com/company/curasen) - [Envisia Therapeutics](https://millionrounds.com/company/envisia-therapeutics) - [Ribometrix](https://millionrounds.com/company/ribometrix) - [Optherion](https://millionrounds.com/company/optherion) - [*LT* LEAD Therapeutics](https://millionrounds.com/company/lead-therapeutics) - [*B* Boragen](https://millionrounds.com/company/boragen) ## Series B 5 - [Milestone Pharmaceuticals](https://millionrounds.com/company/milestone-pharmaceuticals) - [*4M* 4D Molecular](https://millionrounds.com/company/4d-molecular) - [Lumena Pharmaceuticals](https://millionrounds.com/company/lumena-pharmaceuticals) - [Rotation Medical](https://millionrounds.com/company/rotation-medical) - [Cequent Pharmaceuticals](https://millionrounds.com/company/cequent-pharmaceuticals) ## Segment by segment ### Series A 8 startups · $443M raised - [*MT* **Mirum Therapeutics**](https://millionrounds.com/company/mirum-therapeutics) United States $120M - [*RP* **Reneo Pharmaceuticals**](https://millionrounds.com/company/reneo-pharmaceuticals) Reneo Pharmaceuticals is an operator of a pharmaceutical company used to develop therapies for patients with orphan metabolic diseases. United States $105M - [*C* **CuraSen**](https://millionrounds.com/company/curasen) United States $55M - [**Envisia Therapeutics**](https://millionrounds.com/company/envisia-therapeutics) Envisia Therapeutics is a biotechnology company based in Research Triangle Park, North Carolina, established in 2013 by Liquidia T United States $46M - [**Ribometrix**](https://millionrounds.com/company/ribometrix) Ribometrix is a platform therapeutics company that discovers small molecule drugs to treat human diseases. United States $45M - [**Optherion**](https://millionrounds.com/company/optherion) Optherion, Inc., a biotechnology company, develops diagnostic and disease-modifying therapeutics for the management and treatment United States $42M - [*LT* **LEAD Therapeutics**](https://millionrounds.com/company/lead-therapeutics) LEAD Therapeutics is a drug discovery company developing small molecule IND candidates for the treatment of cancer and infectious diseases. United States $20M - [*B* **Boragen**](https://millionrounds.com/company/boragen) United States $10M ### Series B 5 startups · $342M raised - [**Milestone Pharmaceuticals**](https://millionrounds.com/company/milestone-pharmaceuticals) Milestone Pharmaceuticals is a drug development company developing small molecule therapeutics for the treatment of cardiovascular diseases. Canada $110M - [*4M* **4D Molecular**](https://millionrounds.com/company/4d-molecular) United States $90M - [**Lumena Pharmaceuticals**](https://millionrounds.com/company/lumena-pharmaceuticals) Lumena Pharmaceuticals develops oral therapeutics for rare liver diseases to improve liver function and relieve disease symptoms. United States $71M - [**Rotation Medical**](https://millionrounds.com/company/rotation-medical) Rotation Medical develops treatments for rotator cuff disease by reversing disease progression and restoring long-term shoulder function. United States $59M - [**Cequent Pharmaceuticals**](https://millionrounds.com/company/cequent-pharmaceuticals) Cequent is a biopharmaceutical company pioneering the development of novel therapeutics to prevent and treat a wide range of human diseases. United States $12M **How this map is made.** Every startup here works in Biotech and has raised money in a round we track that names Pappas Ventures as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026. ## More portfolio maps [All portfolios](https://millionrounds.com/portfolio-maps) [Sector portfolio **Techstars' AI portfolio** 336 startups · $4.9B](https://millionrounds.com/portfolio-maps/techstars-ai-portfolio)[Sector portfolio **Alumni Ventures' AI portfolio** 302 startups · $36B](https://millionrounds.com/portfolio-maps/us-strategic-tech-fund-an-alumni-ventures-fund-ai-portfolio)[Sector portfolio **Andreessen Horowitz's AI portfolio** 259 startups · $426B](https://millionrounds.com/portfolio-maps/andreessen-horowitz-ai-portfolio)[Sector portfolio **General Catalyst's AI portfolio** 226 startups · $179B](https://millionrounds.com/portfolio-maps/general-catalyst-ai-portfolio)[Sector portfolio **Sequoia Capital's AI portfolio** 209 startups · $543B](https://millionrounds.com/portfolio-maps/sequoia-capital-ai-portfolio)[Sector portfolio **Khosla Ventures' AI portfolio** 176 startups · $251B](https://millionrounds.com/portfolio-maps/khosla-ventures-ai-portfolio) ## Raising from investors like Pappas Ventures? 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