# National Science Foundation's Biotech Investments: 250 Startups in Its Portfolio (2026)

> The 250 Biotech startups National Science Foundation has backed, by stage: $2.0B raised between them. From the rounds we track; updated nightly.

Source: https://millionrounds.com/portfolio-maps/nsf-small-business-innovation-research-small-business-techno-biotech-portfolio (Millionrounds; every figure on the page links to its filing or article)

## Stage not reported

186

- [Mission Bio](https://millionrounds.com/company/mission-bio)
- [Biomason](https://millionrounds.com/company/biomason)
- [Kytopen](https://millionrounds.com/company/kytopen)
- [Vaxess Technologies](https://millionrounds.com/company/vaxess-technologies)
- [Sonavex](https://millionrounds.com/company/sonavex)
- [Eradivir](https://millionrounds.com/company/eradivir)
- [Primrose Bio](https://millionrounds.com/company/primrose-bio)
- [*PS* Prescient Surgical](https://millionrounds.com/company/prescient-surgical)
- [Ancilia Biosciences](https://millionrounds.com/company/ancilia-biosciences)
- [Triton Algae Innovations](https://millionrounds.com/company/triton-algae-innovations)
- [Zeteo Tech](https://millionrounds.com/company/zeteo-tech)
- [Micro-Leads](https://millionrounds.com/company/micro-leads)
- [Caravel Bio](https://millionrounds.com/company/caravel-bio)
- [Cascade Biocatalysts](https://millionrounds.com/company/cascade-biocatalysts)
- [BiomeSense](https://millionrounds.com/company/biomesense)
- [Imbed Biosciences](https://millionrounds.com/company/imbed-biosciences)
- [FYR Diagnostics](https://millionrounds.com/company/fyr-diagnostics)
- [Rubi Laboratories](https://millionrounds.com/company/rubi-laboratories)
- [Pyran Inc.](https://millionrounds.com/company/pyran-inc)
- [Liberate Medical](https://millionrounds.com/company/liberate-medical)
- [CycloPure](https://millionrounds.com/company/cyclopure)
- [Zymochem](https://millionrounds.com/company/zymochem)
- [Inanovate](https://millionrounds.com/company/inanovate)
- [gel-e](https://millionrounds.com/company/gel-e)

+162 more

## Series A

23

- [Caribou Biosciences](https://millionrounds.com/company/caribou-biosciences)
- [ProLynx](https://millionrounds.com/company/prolynx)
- [Think Bioscience](https://millionrounds.com/company/think-bioscience)
- [Manus Bio](https://millionrounds.com/company/manus-bio)
- [Azitra](https://millionrounds.com/company/azitra)
- [Nabla Bio](https://millionrounds.com/company/nabla-bio)
- [Phase Scientific](https://millionrounds.com/company/phase-scientific)
- [GenEdit](https://millionrounds.com/company/genedit)
- [Hinge Bio](https://millionrounds.com/company/hinge-bio)
- [Ramona](https://millionrounds.com/company/ramona)
- [Tacit Therapeutics](https://millionrounds.com/company/tacit-therapeutics)
- [Molecular Assemblies](https://millionrounds.com/company/molecular-assemblies)
- [VeriSIM Life](https://millionrounds.com/company/verisim-life)
- [Amberstone Biosciences](https://millionrounds.com/company/amberstone-biosciences)
- [Abram Scientific](https://millionrounds.com/company/abram-scientific)
- [NeuroFlow](https://millionrounds.com/company/neuroflow)
- [Pow.bio](https://millionrounds.com/company/pow-bio)
- [Verix Health](https://millionrounds.com/company/verix-health)
- [Mytide Therapeutics](https://millionrounds.com/company/mytide-therapeutics)
- [Invictus Medical](https://millionrounds.com/company/invictus-medical)
- [Kalion](https://millionrounds.com/company/kalion)
- [Trace Biosciences](https://millionrounds.com/company/trace-biosciences)
- [OPAL Therapeutics](https://millionrounds.com/company/opal-therapeutics)

## Pre-seed and seed

22

- [Amphix Bio](https://millionrounds.com/company/amphix-bio)
- [iMicrobes](https://millionrounds.com/company/imicrobes)
- [Abalone Bio](https://millionrounds.com/company/abalone-bio)
- [Partillion Bioscience](https://millionrounds.com/company/partillion-bioscience)
- [UNCAGED Innovations](https://millionrounds.com/company/uncaged-innovations)
- [Auxilium Health](https://millionrounds.com/company/auxilium-health)
- [VerImmune](https://millionrounds.com/company/verimmune)
- [dfusion](https://millionrounds.com/company/dfusion)
- [*AB* Auctus Biologics](https://millionrounds.com/company/auctus-biologics)
- [Trilo Therapeutics](https://millionrounds.com/company/trilo-therapeutics)
- [Qualia Oto](https://millionrounds.com/company/qualia-oto)
- [TheMednet](https://millionrounds.com/company/themednet)
- [Cerillo](https://millionrounds.com/company/cerillo)
- [Xanofi](https://millionrounds.com/company/xanofi)
- [GlucoSentient](https://millionrounds.com/company/glucosentient)
- [Klar Scientific](https://millionrounds.com/company/klar-scientific)
- [Bondwell Technologies](https://millionrounds.com/company/bondwell-technologies)
- [O2 RegenTech](https://millionrounds.com/company/o2-regentech)
- [BioHybrid Solutions](https://millionrounds.com/company/biohybrid-solutions)
- [SeeTrue Technology](https://millionrounds.com/company/seetrue-technology)
- [Plumb Pharmaceuticals](https://millionrounds.com/company/plumb-pharmaceuticals)
- [Astria Biosciences](https://millionrounds.com/company/astria-biosciences)

## Series B

11

- [Lucira Health](https://millionrounds.com/company/lucira-health)
- [GRO Biosciences](https://millionrounds.com/company/gro-biosciences)
- [BreezeBio](https://millionrounds.com/company/breezebio)
- [Lygos](https://millionrounds.com/company/lygos)
- [Nanopath](https://millionrounds.com/company/nanopath)
- [SQZ Biotech](https://millionrounds.com/company/sqz-biotech)
- [HealthMyne](https://millionrounds.com/company/healthmyne)
- [DMC Biotechnologies](https://millionrounds.com/company/dmc-biotechnologies)
- [iotaMotion](https://millionrounds.com/company/iotamotion)
- [iVeena](https://millionrounds.com/company/iveena)
- [Cerahelix](https://millionrounds.com/company/cerahelix)

## Series C and later

8

- [Spero Therapeutics](https://millionrounds.com/company/spero-therapeutics)
- [CoreMap](https://millionrounds.com/company/coremap)
- [Terrestrial Bio](https://millionrounds.com/company/terrestrial-bio)
- [Parse Biosciences](https://millionrounds.com/company/parse-biosciences)
- [Symic Bio](https://millionrounds.com/company/symic-bio)
- [ANEUVO](https://millionrounds.com/company/aneuvo)
- [Maui Imaging](https://millionrounds.com/company/maui-imaging)
- [Halo Labs](https://millionrounds.com/company/halo-labs)

## Segment by segment

### Stage not reported

186 startups · $426M raised

- [**Mission Bio**](https://millionrounds.com/company/mission-bio) Mission Bio is a biotechnology company based in South San Francisco, founded in 2014. United States $40M
- [**Biomason**](https://millionrounds.com/company/biomason) Biomason, Inc. United States $37M
- [**Kytopen**](https://millionrounds.com/company/kytopen) Kytopen is a biotechnology company based in Cambridge, Massachusetts, founded in 2017 as an MIT spin-out. United States $35M
- [**Vaxess Technologies**](https://millionrounds.com/company/vaxess-technologies) Vaxess Technologies engages in developing biomedical innovations with a focus on improving access to vaccines. United States $23M
- [**Sonavex**](https://millionrounds.com/company/sonavex) Sonavex is a developer of an imaging technology designed to visualize and quantify critical data to detect anastomotic blood clots. United States $20M
- [**Eradivir**](https://millionrounds.com/company/eradivir) Eradivir is a clinical-stage biotechnology company based in West Lafayette, Indiana, founded in 2020. United States $20M
- [**Primrose Bio**](https://millionrounds.com/company/primrose-bio) Primrose Bio is a biotechnology company that focuses on discovery, development, and manufacturing of new molecules. United States $17M
- [*PS* **Prescient Surgical**](https://millionrounds.com/company/prescient-surgical) Prescient Surgical, Inc. United States $16M

### Series A

23 startups · $640M raised

- [**Caribou Biosciences**](https://millionrounds.com/company/caribou-biosciences) Caribou Biosciences is a biotechnology company that develops CRISPR technologies and allogenic cell therapies for oncology. United States $139M
- [**ProLynx**](https://millionrounds.com/company/prolynx) Prolynx is a clinical-stage biotechnology company based in the San Francisco Bay Area, founded in 2009. United States $70M
- [**Think Bioscience**](https://millionrounds.com/company/think-bioscience) Think Bioscience is a synthetic biology company located in Boulder, Colorado. United States $55M
- [**Manus Bio**](https://millionrounds.com/company/manus-bio) Manus Bio develops an advanced fermentation technology to recreate plant processes in microorganisms. United States $52M
- [**Azitra**](https://millionrounds.com/company/azitra) Azitra is a clinical-stage medical dermatology company developing microbiome-based novel therapeutics to treat skin conditions and diseases. United States $49M
- [**Nabla Bio**](https://millionrounds.com/company/nabla-bio) Nabla Bio is a biotechnology company founded in 2020 that focuses on developing selective and functional drugs for previously undr United States $37M
- [**Phase Scientific**](https://millionrounds.com/company/phase-scientific) Phase Scientific provides tool for health care industry. Hong Kong SAR China $34M
- [**GenEdit**](https://millionrounds.com/company/genedit) GenEdit develops next generation therapeutics for genetic diseases through safe and efficient CRISPR/Cas9 delivery. United States $33M

### Pre-seed and seed

22 startups · $66M raised

- [**Amphix Bio**](https://millionrounds.com/company/amphix-bio) Amphix Bio is a biotechnology company that develops regenerative medicine therapies using a platform of supramolecular therapeutic peptides. United States $13M
- [**iMicrobes**](https://millionrounds.com/company/imicrobes) iMicrobes, officially known as Industrial Microbes, Inc., is a synthetic biology company based in Alameda, California. United States $10M
- [**Abalone Bio**](https://millionrounds.com/company/abalone-bio) Abalone Bio is a preclinical-stage biotechnology company based in Emeryville, California, founded in 2017. United States $7.6M
- [**Partillion Bioscience**](https://millionrounds.com/company/partillion-bioscience) Partillion Bioscience is an early-stage life science company developing a functional single-cell analysis platform. United States $7.1M
- [**UNCAGED Innovations**](https://millionrounds.com/company/uncaged-innovations) UNCAGED Innovations is a biomaterials company combining the power of nature and technology to reimagine leather. United States $5.6M
- [**Auxilium Health**](https://millionrounds.com/company/auxilium-health) Auxilium Health is creating low-cost, smart biomaterials for difficult-to-heal wounds. United States $4.5M
- [**VerImmune**](https://millionrounds.com/company/verimmune) VerImmune is a biotechnology company founded in 2019, focused on developing innovative cancer immunotherapies. United States $4.5M
- [**dfusion**](https://millionrounds.com/company/dfusion) dfusion, a team of scientists and innovators, develops technology to promote evidence-based, health-related behavioral changes. United States $2.8M

### Series B

11 startups · $385M raised

- [**Lucira Health**](https://millionrounds.com/company/lucira-health) Lucira Health is a biotechnology company that offers disposable test kits to detect RNA and DNA of infectious diseases. United States $95M
- [**GRO Biosciences**](https://millionrounds.com/company/gro-biosciences) GRO Biosciences, also known as GRObio, is a biotechnology company based in Cambridge, Massachusetts, founded in 2016. United States $87M
- [**BreezeBio**](https://millionrounds.com/company/breezebio) BreezeBio, Inc., based in South San Francisco, California, is a biotechnology company founded in 2016 by Dr. United States $60M
- [**Lygos**](https://millionrounds.com/company/lygos) Lygos provides biotechnology solutions for today’s renewable chemical challenges. United States $35M
- [**Nanopath**](https://millionrounds.com/company/nanopath) Nanopath Inc. United States $25M
- [**SQZ Biotech**](https://millionrounds.com/company/sqz-biotech) SQZ Biotech features a cell engineering technology designed to deliver a diverse set of materials into patient cells. United States $23M
- [**HealthMyne**](https://millionrounds.com/company/healthmyne) HealthMyne provides clinicians with evidence-based imaging insights and solutions. United States $20M
- [**DMC Biotechnologies**](https://millionrounds.com/company/dmc-biotechnologies) DMC Biotechnologies produces bio-based chemicals using fermentation. United States $19M

### Series C and later

8 startups · $453M raised

- [**Spero Therapeutics**](https://millionrounds.com/company/spero-therapeutics) Spero Therapeutics develops therapeutics for treatment of gram-negative infections. United States $199M
- [**CoreMap**](https://millionrounds.com/company/coremap) CoreMap is a medical device company founded in 2016, focused on advanced diagnostic technology for electrophysiologists. United States $57M
- [**Terrestrial Bio**](https://millionrounds.com/company/terrestrial-bio) Terrestrial Bio engages in developing biomedical innovations with a focus on improving access to vaccines. United States $50M
- [**Parse Biosciences**](https://millionrounds.com/company/parse-biosciences) Parse Biosciences is a biotechnology startup company that develops single-cell sequencing kit solutions for researchers. United States $50M
- [**Symic Bio**](https://millionrounds.com/company/symic-bio) Symic Bio is a biopharmaceutical company based in San Francisco, California, founded in 2012. United States $41M
- [**ANEUVO**](https://millionrounds.com/company/aneuvo) ANEUVO, based in Los Angeles, California, is a bioelectronic medical device company focused on developing innovative therapies for United States $22M
- [**Maui Imaging**](https://millionrounds.com/company/maui-imaging) MAUI Imaging is a medical imaging company dedicated to enhancing ultrasound technology. United States $21M
- [**Halo Labs**](https://millionrounds.com/company/halo-labs) United States $13M

**How this map is made.** Every startup here works in Biotech and has raised money in a round we track that names National Science Foundation as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026.

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