# Longwood Fund's Biotech Investments: 27 Startups in Its Portfolio (2026)

> The 27 Biotech startups Longwood Fund has backed, by stage: $2.4B raised between them. From the rounds we track; updated nightly.

Source: https://millionrounds.com/portfolio-maps/longwood-fund-biotech-portfolio (Millionrounds; every figure on the page links to its filing or article)

## Series B

11

- [*N* Neomorph](https://millionrounds.com/company/neomorph)
- [Mediar Therapeutics](https://millionrounds.com/company/mediar-therapeutics)
- [AAVantgarde Bio](https://millionrounds.com/company/aavantgarde-bio)
- [Sidewinder Therapeutics](https://millionrounds.com/company/sidewinder-therapeutics)
- [Lassen Therapeutics](https://millionrounds.com/company/lassen-therapeutics)
- [TScan Therapeutics](https://millionrounds.com/company/tscan-therapeutics)
- [XyloCor Therapeutics](https://millionrounds.com/company/xylocor-therapeutics)
- [Avenzo Therapeutics](https://millionrounds.com/company/avenzo-therapeutics)
- [Immunitas Therapeutics](https://millionrounds.com/company/immunitas-therapeutics)
- [*AB* Axial Biotherapeutics](https://millionrounds.com/company/axial-biotherapeutics)
- [*KT* Khartis Therapeutics](https://millionrounds.com/company/khartis-therapeutics)

## Series A

10

- [Tome Biosciences](https://millionrounds.com/company/tome-biosciences)
- [Newleos Therapeutics](https://millionrounds.com/company/newleos-therapeutics)
- [Photys Therapeutics](https://millionrounds.com/company/photys-therapeutics)
- [*2T* 27-8 Therapeutics](https://millionrounds.com/company/27-8-therapeutics)
- [*PT* Progentos Therapeutics](https://millionrounds.com/company/progentos-therapeutics)
- [*WT* Wereworld Therapeutics](https://millionrounds.com/company/wereworld-therapeutics)
- [ImmuneID](https://millionrounds.com/company/immuneid)
- [Solu Therapeutics](https://millionrounds.com/company/solu-therapeutics)
- [Carbon Biosciences](https://millionrounds.com/company/carbon-biosciences)
- [*RM* Recros Medica](https://millionrounds.com/company/recros-medica)

## Series C and later

4

- [ArcherDX](https://millionrounds.com/company/archerdx)
- [Calithera Biosciences](https://millionrounds.com/company/calithera-biosciences)
- [Pulmocide](https://millionrounds.com/company/pulmocide)
- [Channel Medsystems](https://millionrounds.com/company/channel-medsystems)

## Stage not reported

2

- [Evommune](https://millionrounds.com/company/evommune)
- [Werewolf Therapeutics](https://millionrounds.com/company/werewolf-therapeutics)

## Segment by segment

### Series B

11 startups · $1.1B raised

- [*N* **Neomorph**](https://millionrounds.com/company/neomorph) United States $209M
- [**Mediar Therapeutics**](https://millionrounds.com/company/mediar-therapeutics) Mediar Therapeutics is a clinical-stage biotechnology company based in Boston, Massachusetts, founded in 2018-2019. United States $161M
- [**AAVantgarde Bio**](https://millionrounds.com/company/aavantgarde-bio) AAVantgarde Bio is developing gene therapies for inherited retinal disorders. Italy $141M
- [**Sidewinder Therapeutics**](https://millionrounds.com/company/sidewinder-therapeutics) Sidewinder Therapeutics is a biotechnology company that offers life-saving therapies for cancer and rare diseases. United States $137M
- [**Lassen Therapeutics**](https://millionrounds.com/company/lassen-therapeutics) Lassen Therapeutics is a clinical-stage biopharmaceutical company based in San Diego, California. United States $85M
- [**TScan Therapeutics**](https://millionrounds.com/company/tscan-therapeutics) TScan Therapeutics is a biopharmaceutical company focused on the development of immunotherapy treatments for cancer. United States $78M
- [**XyloCor Therapeutics**](https://millionrounds.com/company/xylocor-therapeutics) XyloCor Therapeutics is a bio-pharmaceutical company intended to develop gene therapy for people with advanced coronary artery disease. United States $68M
- [**Avenzo Therapeutics**](https://millionrounds.com/company/avenzo-therapeutics) Developing the next generation of oncology therapies for patients. United States $60M

### Series A

10 startups · $724M raised

- [**Tome Biosciences**](https://millionrounds.com/company/tome-biosciences) Tome Biosciences is a biotechnology company based in Watertown, MA, focused on advancing programmable genomic integration (PGI) to United States $213M
- [**Newleos Therapeutics**](https://millionrounds.com/company/newleos-therapeutics) Newleos Therapeutics is a clinical-stage neuroscience and biotechnology company based in Boston, Massachusetts. United States $94M
- [**Photys Therapeutics**](https://millionrounds.com/company/photys-therapeutics) Photys Therapeutics is a biotechnology and pharmaceutical research company founded in 2021 and based in Waltham, Massachusetts. United States $75M
- [*2T* **27-8 Therapeutics**](https://millionrounds.com/company/27-8-therapeutics) United States $65M
- [*PT* **Progentos Therapeutics**](https://millionrounds.com/company/progentos-therapeutics) Progentos Therapeutics develops an approach to treat multiple sclerosis that stimulates the body's natural repair mechanisms. United States $65M
- [*WT* **Wereworld Therapeutics**](https://millionrounds.com/company/wereworld-therapeutics) United States $56M
- [**ImmuneID**](https://millionrounds.com/company/immuneid) ImmuneID is a precision immunology company. - $50M
- [**Solu Therapeutics**](https://millionrounds.com/company/solu-therapeutics) Solu Therapeutics is a Boston-based clinical-stage biotechnology company focused on developing precision medicines to target and e United States $41M

### Series C and later

4 startups · $427M raised

- [**ArcherDX**](https://millionrounds.com/company/archerdx) ArcherDX is a biotechnology firm specializing in cancer research. United States $150M
- [**Calithera Biosciences**](https://millionrounds.com/company/calithera-biosciences) Calithera Biosciences is a pharmaceutical company developing novel small molecule therapeutics for the treatment of cancer. United States $115M
- [**Pulmocide**](https://millionrounds.com/company/pulmocide) Pulmocide is a private biopharmaceutical company based in London, United Kingdom, founded in 2007. United Kingdom $110M
- [**Channel Medsystems**](https://millionrounds.com/company/channel-medsystems) Channel Medsystems is a medical device company offering cryotherapy devices for endometrial cryoablation. United States $52M

### Stage not reported

2 startups · $175M raised

- [**Evommune**](https://millionrounds.com/company/evommune) Evommune is a biotechnology company that develops therapeutics that halt progressive disease and address their symptoms. United States $125M
- [**Werewolf Therapeutics**](https://millionrounds.com/company/werewolf-therapeutics) Werewolf Therapeutics operates as an oncology biotherapeutics company. United States $50M

**How this map is made.** Every startup here works in Biotech and has raised money in a round we track that names Longwood Fund as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026.

## More portfolio maps

[All portfolios](https://millionrounds.com/portfolio-maps)

[Co-investors **Who invests with Longwood Fund** 27 co-investors](https://millionrounds.com/portfolio-maps/longwood-fund-co-investors)[Sector portfolio **Techstars' AI portfolio** 336 startups · $4.9B](https://millionrounds.com/portfolio-maps/techstars-ai-portfolio)[Sector portfolio **Alumni Ventures' AI portfolio** 302 startups · $36B](https://millionrounds.com/portfolio-maps/us-strategic-tech-fund-an-alumni-ventures-fund-ai-portfolio)[Sector portfolio **Andreessen Horowitz's AI portfolio** 259 startups · $426B](https://millionrounds.com/portfolio-maps/andreessen-horowitz-ai-portfolio)[Sector portfolio **General Catalyst's AI portfolio** 226 startups · $179B](https://millionrounds.com/portfolio-maps/general-catalyst-ai-portfolio)[Sector portfolio **Sequoia Capital's AI portfolio** 209 startups · $543B](https://millionrounds.com/portfolio-maps/sequoia-capital-ai-portfolio)

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