# Janus Henderson Investors' Investments in United States: 111 Startups by Sector (2026)

> The 111 startups in the United States that Janus Henderson Investors has backed, by sector: Biotech, Pharma and AI and more. $23B raised. Updated nightly.

Source: https://millionrounds.com/portfolio-maps/janus-henderson-investors-investments-united-states (Millionrounds; every figure on the page links to its filing or article)

## Biotech

73

- [Tango Therapeutics](https://millionrounds.com/company/tango-therapeutics)
- [Definium Therapeutics](https://millionrounds.com/company/definium-therapeutics)
- [Kymera Therapeutics](https://millionrounds.com/company/kymera-therapeutics)
- [Avidity Biosciences](https://millionrounds.com/company/avidity-biosciences)
- [Structure Therapeutics](https://millionrounds.com/company/structure-therapeutics)
- [Tyra Biosciences](https://millionrounds.com/company/tyra-biosciences)
- [Kailera Therapeutics](https://millionrounds.com/company/kailera-therapeutics)
- [Phathom Pharmaceuticals](https://millionrounds.com/company/phathom-pharmaceuticals)
- [Akero Therapeutics](https://millionrounds.com/company/akero-therapeutics)
- [Nuvalent](https://millionrounds.com/company/nuvalent)
- [Enliven Therapeutics](https://millionrounds.com/company/enliven-therapeutics)
- [Artiva Biotherapeutics](https://millionrounds.com/company/artiva-biotherapeutics)
- [Immunic Therapeutics](https://millionrounds.com/company/immunic-therapeutics)
- [Encoded Therapeutics](https://millionrounds.com/company/encoded-therapeutics)
- [Janux Therapeutics](https://millionrounds.com/company/janux-therapeutics)
- [*DT* Dice Therapeutics](https://millionrounds.com/company/dice-therapeutics)
- [Solid Biosciences](https://millionrounds.com/company/solid-biosciences)
- [Star Therapeutics](https://millionrounds.com/company/star-therapeutics)
- [4D Molecular Therapeutics](https://millionrounds.com/company/4d-molecular-therapeutics)
- [Disc Medicine](https://millionrounds.com/company/disc-medicine)
- [Stoke Therapeutics](https://millionrounds.com/company/stoke-therapeutics)
- [Centessa Pharmaceuticals](https://millionrounds.com/company/centessa-pharmaceuticals)
- [Nkarta Therapeutics](https://millionrounds.com/company/nkarta-therapeutics)
- [CG Oncology](https://millionrounds.com/company/cg-oncology)

+49 more

## Pharma

29

- [Dianthus Therapeutics](https://millionrounds.com/company/dianthus-therapeutics)
- [Vaxcyte](https://millionrounds.com/company/vaxcyte)
- [Korsana Biosciences](https://millionrounds.com/company/korsana-biosciences)
- [Parabilis Medicines](https://millionrounds.com/company/parabilis-medicines)
- [Maze Therapeutics](https://millionrounds.com/company/maze-therapeutics)
- [Compass Therapeutics](https://millionrounds.com/company/compass-therapeutics)
- [Metsera](https://millionrounds.com/company/metsera)
- [Edgewise Therapeutics](https://millionrounds.com/company/edgewise-therapeutics)
- [Jade Biosciences](https://millionrounds.com/company/jade-biosciences)
- [Day One Biopharmaceuticals](https://millionrounds.com/company/day-one-biopharmaceuticals)
- [Ovid Therapeutics](https://millionrounds.com/company/ovid-therapeutics)
- [Ocugen](https://millionrounds.com/company/ocugen)
- [Bicara Therapeutics](https://millionrounds.com/company/bicara-therapeutics)
- [Monopar](https://millionrounds.com/company/monopar)
- [Angitia Biopharmaceuticals](https://millionrounds.com/company/angitia-biopharmaceuticals)
- [Cyteir Therapeutics](https://millionrounds.com/company/cyteir-therapeutics)
- [Diagonal Therapeutics](https://millionrounds.com/company/diagonal-therapeutics)
- [Claris Biotherapeutics](https://millionrounds.com/company/claris-biotherapeutics)
- [Curevo](https://millionrounds.com/company/curevo)
- [Shattuck Labs](https://millionrounds.com/company/shattuck-labs)
- [Attralus](https://millionrounds.com/company/attralus)
- [Entact Bio](https://millionrounds.com/company/entact-bio)
- [Elevation Oncology](https://millionrounds.com/company/elevation-oncology)
- [Caldera Therapeutics](https://millionrounds.com/company/caldera-therapeutics)

+5 more

## AI

3

- [HeartFlow](https://millionrounds.com/company/heartflow)
- [Arbor Biotechnologies](https://millionrounds.com/company/arbor-biotechnologies)
- [Tare](https://millionrounds.com/company/tare)

## Logistics

2

- [Loadsmart](https://millionrounds.com/company/loadsmart)
- [Xos Trucks](https://millionrounds.com/company/xos-trucks)

## Healthtech

2

- [IntelyCare](https://millionrounds.com/company/intelycare)
- [Magnolia Medical Technologies](https://millionrounds.com/company/magnolia-medical-technologies)

## Consumer Goods

2

- [Neuro](https://millionrounds.com/company/neuro)
- [*OB* Owlet Baby Care](https://millionrounds.com/company/owlet-baby-care)

## Segment by segment

### Biotech

73 startups · $17B raised

- [**Tango Therapeutics**](https://millionrounds.com/company/tango-therapeutics) Tango Therapeutics is a biotechnology company that is developing next generation cancer therapies. United States $852M
- [**Definium Therapeutics**](https://millionrounds.com/company/definium-therapeutics) Definium Therapeutics provides psychedelic-inspired medicines and therapies for substance abuse disorders and other mental illnesses. United States $805M
- [**Kymera Therapeutics**](https://millionrounds.com/company/kymera-therapeutics) Kymera Therapeutics is a biotechnology company that specializes in the field of targeted protein degradation. United States $799M
- [**Avidity Biosciences**](https://millionrounds.com/company/avidity-biosciences) Synapse Energy Economics is a consulting firm providing economic and policy analysis for the electric power sector. United States $790M
- [**Structure Therapeutics**](https://millionrounds.com/company/structure-therapeutics) Structure Therapeutics specializes in the discovery and development of drugs against a type of targets called GPCR. United States $748M
- [**Tyra Biosciences**](https://millionrounds.com/company/tyra-biosciences) Tyra Biosciences is a biotechnology company targeting new pathways of acquired resistance in oncology with purpose-built drugs. United States $600M
- [**Kailera Therapeutics**](https://millionrounds.com/company/kailera-therapeutics) Kailera Therapeutics develops next-generation injectable and oral therapies for chronic weight management. United States $600M
- [**Phathom Pharmaceuticals**](https://millionrounds.com/company/phathom-pharmaceuticals) Phathom Pharmaceuticals is a biopharmaceutical company. United States $530M

### Pharma

29 startups · $5.2B raised

- [**Dianthus Therapeutics**](https://millionrounds.com/company/dianthus-therapeutics) Dianthus Therapeutics is a biotech company developing new treatments for serious autoimmune diseases using a more targeted approach. United States $719M
- [**Vaxcyte**](https://millionrounds.com/company/vaxcyte) Vaxcyte focuses on developing vaccines designed to prevent or treat some of the most common and deadly infectious diseases worldwide. United States $633M
- [**Korsana Biosciences**](https://millionrounds.com/company/korsana-biosciences) Korsana Biosciences develops THETA-enabled antibody therapies for neurodegenerative diseases including Alzheimer’s. United States $530M
- [**Parabilis Medicines**](https://millionrounds.com/company/parabilis-medicines) Parabilis Medicines is a Grupo Bugio is a biopharmaceutical firm that specializes in creating medicines. United States $380M
- [**Maze Therapeutics**](https://millionrounds.com/company/maze-therapeutics) Maze Therapeutics is an operator of a biotechnology firm used to focus on translating genetic insights into new medicines. United States $300M
- [**Compass Therapeutics**](https://millionrounds.com/company/compass-therapeutics) Compass Therapeutics is a biopharmaceutical company that focuses on drugging the immune system to treat human diseases. United States $257M
- [**Metsera**](https://millionrounds.com/company/metsera) Metsera operates as a clinical-stage biopharmaceutical company. United States $215M
- [**Edgewise Therapeutics**](https://millionrounds.com/company/edgewise-therapeutics) Edgewise Therapeutics is a clinical-stage biopharmaceutical company focused on the discovery, development and commercialization. United States $200M

### AI

3 startups · $673M raised

- [**HeartFlow**](https://millionrounds.com/company/heartflow) HeartFlow is a medical technology company that provides various methods of diagnosis and treatment of cardiovascular disease. United States $586M
- [**Arbor Biotechnologies**](https://millionrounds.com/company/arbor-biotechnologies) Arbor Biotechnologies is a gene editing company based in Cambridge, Massachusetts, dedicated to developing genomic medicines for a United States $74M
- [**Tare**](https://millionrounds.com/company/tare) Tare is an AI-powered email marketing solution that makes data-driven automation easy for modern e-commerce brands. United States $13M

### Logistics

2 startups · $27M raised

- [**Loadsmart**](https://millionrounds.com/company/loadsmart) Loadsmart is a logistics technology company based in Chicago, founded in 2014. United States $25M
- [**Xos Trucks**](https://millionrounds.com/company/xos-trucks) Xos Trucks specializes in the field of manufacturing fully electric commercial vehicles. United States $2.4M

### Healthtech

2 startups · $195M raised

- [**IntelyCare**](https://millionrounds.com/company/intelycare) IntelyCare is an AI-based healthcare workforce management platform that connects nursing professionals with healthcare facilities United States $126M
- [**Magnolia Medical Technologies**](https://millionrounds.com/company/magnolia-medical-technologies) Magnolia Medical Technologies is a Seattle-based healthcare company focused on improving diagnostic accuracy for sepsis detection United States $69M

### Consumer Goods

2 startups · $254M raised

- [**Neuro**](https://millionrounds.com/company/neuro) Neuro is a functional gum and mint company creating smarter ways to help energize, calm, and focus the mind. United States $200M
- [*OB* **Owlet Baby Care**](https://millionrounds.com/company/owlet-baby-care) Owlet Baby Care offers a health monitor that allows parents to view their child's vital signs in real-time. United States $54M

**How this map is made.** Every startup here has raised money in a round we track that names Janus Henderson Investors as an investor and is based in United States. Each sits under its main sector, read from its rounds, and each shows its best-funded first. Rebuilt nightly; updated 15 November 2026.

## More portfolio maps

[All portfolios](https://millionrounds.com/portfolio-maps)

[Portfolio map **Janus Henderson Investors portfolio map** 128 startups · $28B](https://millionrounds.com/portfolio-maps/janus-henderson-investors-portfolio-map)[Sector portfolio **Janus Henderson Investors' Biotech portfolio** 89 startups · $21B](https://millionrounds.com/portfolio-maps/janus-henderson-investors-biotech-portfolio)[Co-investors **Who invests with Janus Henderson Investors** 80 co-investors](https://millionrounds.com/portfolio-maps/janus-henderson-investors-co-investors)[Sector portfolio **Janus Henderson Investors' Pharma portfolio** 35 startups · $6.2B](https://millionrounds.com/portfolio-maps/janus-henderson-investors-pharma-portfolio)[Investments abroad **DST Global's investments in the United States** 44 startups · $240B](https://millionrounds.com/portfolio-maps/dst-global-investments-united-states)[Investments abroad **3i Group's investments in the United States** 24 startups · $1.8B](https://millionrounds.com/portfolio-maps/3i-group-investments-united-states)

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