# Essence VC's AI Investments: 22 Startups in Its Portfolio (2026)

> The 22 AI startups Essence VC has backed, by stage: $566M raised between them. From the rounds we track; updated nightly.

Source: https://millionrounds.com/portfolio-maps/essence-vc-ai-portfolio (Millionrounds; every figure on the page links to its filing or article)

## Series A

10

- [Kite](https://millionrounds.com/company/kite)
- [Cline](https://millionrounds.com/company/cline)
- [Restate](https://millionrounds.com/company/restate)
- [*T* Teleskope](https://millionrounds.com/company/teleskope)
- [HumanSignal](https://millionrounds.com/company/humansignal)
- [Distributional](https://millionrounds.com/company/distributional)
- [Nuon](https://millionrounds.com/company/nuon)
- [Clarify](https://millionrounds.com/company/clarify)
- [Continual](https://millionrounds.com/company/continual)
- [Magic Patterns](https://millionrounds.com/company/magic-patterns)

## Pre-seed and seed

7

- [*SK* Standard Kernel](https://millionrounds.com/company/standard-kernel)
- [Letta](https://millionrounds.com/company/letta)
- [OpenInfer](https://millionrounds.com/company/openinfer)
- [Log10](https://millionrounds.com/company/log10)
- [Fearn](https://millionrounds.com/company/fearn)
- [Superframe](https://millionrounds.com/company/superframe)
- [Mixpeek](https://millionrounds.com/company/mixpeek)

## Stage not reported

3

- [Devron](https://millionrounds.com/company/devron)
- [Graft](https://millionrounds.com/company/graft)
- [Elotl](https://millionrounds.com/company/elotl)

## Series B

2

- [*Y* Yurts](https://millionrounds.com/company/yurts)
- [ComfyUI](https://millionrounds.com/company/comfyui)

## Segment by segment

### Series A

10 startups · $411M raised

- [**Kite**](https://millionrounds.com/company/kite) Kite augments coding environment with the use of internet’s programming knowledge and machine learning. United States $236M
- [**Cline**](https://millionrounds.com/company/cline) Cline is an open-source AI coding agent company based in San Francisco, California, founded in 2024 by Saoud Rizwan. United States $27M
- [**Restate**](https://millionrounds.com/company/restate) Restate is a modern mortgage platform for mortgage loan officers and their clients. Germany $27M
- [*T* **Teleskope**](https://millionrounds.com/company/teleskope) United States $25M
- [**HumanSignal**](https://millionrounds.com/company/humansignal) HumanSignal is a software development company based in San Francisco, founded in 2019 and formerly known as Heartex. United States $25M
- [**Distributional**](https://millionrounds.com/company/distributional) Distributional is an enterprise technology company focused on creating a modern platform for safe and reliable AI. United States $19M
- [**Nuon**](https://millionrounds.com/company/nuon) Nuon Medical, founded in 2010 by Alain Dijkstra, is a technology partner that enhances conventional cosmetic packaging by integrat United States $17M
- [**Clarify**](https://millionrounds.com/company/clarify) Clarify is an AI-native, autonomous CRM platform designed for modern revenue teams. United States $15M

### Pre-seed and seed

7 startups · $56M raised

- [*SK* **Standard Kernel**](https://millionrounds.com/company/standard-kernel) United States $20M
- [**Letta**](https://millionrounds.com/company/letta) Letta is a San Francisco-based AI startup founded in 2024, specializing in an operating system for building stateful AI agents. United States $10M
- [**OpenInfer**](https://millionrounds.com/company/openinfer) OpenInfer is an AI inference infrastructure company based in San Mateo, California, founded in 2024. United States $8.0M
- [**Log10**](https://millionrounds.com/company/log10) Log10 is a food safety testing and quality services company. United States $7.2M
- [**Fearn**](https://millionrounds.com/company/fearn) Fearn was founded by leading patent professionals from top-tier law firms, and PhDs in artificial intelligence. United States $5.5M
- [**Superframe**](https://millionrounds.com/company/superframe) Superframe is an AI software company based in San Francisco, California, founded in 2023. United States $5.0M
- [**Mixpeek**](https://millionrounds.com/company/mixpeek) Mixpeek is a multimodal search and indexing platform that processes unstructured data, including videos, images, audio, documents, and text. United States $650K

### Stage not reported

3 startups · $29M raised

- [**Devron**](https://millionrounds.com/company/devron) Devron is a federated data science platform that helps teams build and train AI models on distributed and private data without the United States $14M
- [**Graft**](https://millionrounds.com/company/graft) Our Modern AI platform enables anyone to build production-ready AI apps in a few clicks. United States $10M
- [**Elotl**](https://millionrounds.com/company/elotl) Elotl is a San Francisco-based company that specializes in developing a nodeless Kubernetes platform and AI infrastructure engine. United States $5.0M

### Series B

2 startups · $70M raised

- [*Y* **Yurts**](https://millionrounds.com/company/yurts) United States $40M
- [**ComfyUI**](https://millionrounds.com/company/comfyui) ComfyUI is a San Francisco-based startup founded in 2023, focusing on an open-source, node-based AI creation engine. United States $30M

**How this map is made.** Every startup here works in AI and has raised money in a round we track that names Essence VC as an investor. Each sits under the stage of its latest round. Rebuilt nightly; updated 15 November 2026.

## More portfolio maps

[All portfolios](https://millionrounds.com/portfolio-maps)

[Co-investors **Who invests with Essence VC** 20 co-investors](https://millionrounds.com/portfolio-maps/essence-vc-co-investors)[Sector portfolio **Techstars' AI portfolio** 336 startups · $4.9B](https://millionrounds.com/portfolio-maps/techstars-ai-portfolio)[Sector portfolio **Alumni Ventures' AI portfolio** 302 startups · $36B](https://millionrounds.com/portfolio-maps/us-strategic-tech-fund-an-alumni-ventures-fund-ai-portfolio)[Sector portfolio **Andreessen Horowitz's AI portfolio** 259 startups · $426B](https://millionrounds.com/portfolio-maps/andreessen-horowitz-ai-portfolio)[Sector portfolio **General Catalyst's AI portfolio** 226 startups · $179B](https://millionrounds.com/portfolio-maps/general-catalyst-ai-portfolio)[Sector portfolio **Sequoia Capital's AI portfolio** 209 startups · $543B](https://millionrounds.com/portfolio-maps/sequoia-capital-ai-portfolio)

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